PMC Links for Gene (Select 54933) - PMC

Select item 30900191.

Mammalian EGF receptor activation by the rhomboid protease RHBDL2

Colin Adrain, Kvido Strisovsky, Markus Zettl, Landian Hu, Marius K Lemberg, Matthew Freeman

EMBO Rep. 2011 May 1; 12(5): 421–427. Published online 2011 Apr 15. doi: 10.1038/embor.2011.50

PMCID:: PMC3090019

Select item 96467332.

RHBDL2 promotes the proliferation, migration, and invasion of pancreatic cancer by stabilizing the N1ICD via the OTUD7B and activating the Notch signaling pathway

Shiyu Chen, Kun Cai, Dijie Zheng, Yanqing Liu, Lin Li, Zhiwei He, Chengyi Sun, Chao Yu

Cell Death Dis. 2022 Nov; 13(11): 945. Published online 2022 Nov 9. doi: 10.1038/s41419-022-05379-3

PMCID:: PMC9646733

Abstract Article PDF–9.0M

Select item 32886423.

Meta-analyses identify 13 novel loci associated with age at menopause and highlights DNA repair and immune pathways

Lisette Stolk, John RB Perry, Daniel I Chasman, Chunyan He, Massimo Mangino, Patrick Sulem, Maja Barbalic, Linda Broer, Enda M Byrne, Florian Ernst, Tõnu Esko, Nora Franceschini, Daniel F Gudbjartsson, Jouke-Jan Hottenga, Peter Kraft, Patick F McArdle, Eleonora Porcu, So-Youn Shin, Albert V Smith, Sophie van Wingerden, Guangju Zhai, Wei V Zhuang, Eva Albrecht, Behrooz Z Alizadeh, Thor Aspelund, Stefania Bandinelli, Lovorka Barac Lauc, Jacques S Beckmann, Mladen Boban, Eric Boerwinkle, Frank J Broekmans, Andrea Burri, Harry Campbell, Stephen J Chanock, Constance Chen, Marilyn C Cornelis, Tanguy Corre, Andrea D Coviello, Pio d’Adamo, Gail Davies, Ulf de Faire, Eco JC de Geus, Ian J Deary, George VZ Dedoussis, Panagiotis Deloukas, Shah Ebrahim, Gudny Eiriksdottir, Valur Emilsson, Johan G Eriksson, Bart CJM Fauser, Liana Ferreli, Luigi Ferrucci, Krista Fischer, Aaron R Folsom, Melissa E Garcia, Paolo Gasparini, Christian Gieger, Nicole Glazer, Diederick E Grobbee, Per Hall, Toomas Haller, Susan E Hankinson, Merli Hass, Caroline Hayward, Andrew C Heath, Albert Hofman, Erik Ingelsson, A Cecile JW Janssens, Andrew D Johnson, David Karasik, Sharon LR Kardia, Jules Keyzer, Douglas P Kiel, Ivana Kolcic, Zoltán Kutalik, Jari Lahti, Sandra Lai, Triin Laisk, Joop SE Laven, Debbie A Lawlor, Jianjun Liu, Lorna M Lopez, Yvonne V Louwers, Patrik KE Magnusson, Mara Marongiu, Nicholas G Martin, Irena Martinovic Klaric, Corrado Masciullo, Barbara McKnight, Sarah E Medland, David Melzer, Vincent Mooser, Pau Navarro, Anne B Newman, Dale R Nyholt, N. Charlotte Onland-Moret, Aarno Palotie, Guillaume Paré, Alex N Parker, Nancy L Pedersen, Petra HM Peeters, Giorgio Pistis, Andrew S Plump, Ozren Polasek, Victor JM Pop, Bruce M Psaty, Katri Räikkönen, Emil Rehnberg, Jerome I Rotter, Igor Rudan, Cinzia Sala, Andres Salumets, Angelo Scuteri, Andrew Singleton, Jennifer A Smith, Harold Snieder, Nicole Soranzo, Simon N Stacey, John M Starr, Maria G Stathopoulou, Kathleen Stirrups, Ronald P Stolk, Unnur Styrkarsdottir, Yan V Sun, Albert Tenesa, Barbara Thorand, Daniela Toniolo, Laufey Tryggvadottir, Kim Tsui, Sheila Ulivi, Rob M van Dam, Yvonne T van der Schouw, Carla H van Gils, Peter van Nierop, Jacqueline M Vink, Peter M Visscher, Marlies Voorhuis, Gérard Waeber, Henri Wallaschofski, H Erich Wichmann, Elisabeth Widen, Colette JM Wijnands-van Gent, Gonneke Willemsen, James F Wilson, Bruce HR Wolffenbuttel, Alan F Wright, Laura M Yerges-Armstrong, Tatijana Zemunik, Lina Zgaga, M. Carola Zillikens, Marek Zygmunt, The LifeLines Cohort Study, Alice M Arnold, Dorret I Boomsma, Julie E. Buring, Laura Crisponi, Ellen W Demerath, Vilmundur Gudnason, Tamara B Harris, Frank B Hu, David J Hunter, Lenore J Launer, Andres Metspalu, Grant W Montgomery, Ben A Oostra, Paul M Ridker, Serena Sanna, David Schlessinger, Tim D Spector, Kari Stefansson, Elizabeth A Streeten, Unnur Thorsteinsdottir, Manuela Uda, André G Uitterlinden, Cornelia M van Duijn, Henry Völzke, Anna Murray, Joanne M Murabito, Jenny A Visser, Kathryn L Lunetta

Nat Genet. Author manuscript; available in PMC 2012 Sep 1.

Published in final edited form as: Nat Genet. 2012 Mar; 44(3): 260–268. Published online 2012 Jan 22. doi: 10.1038/ng.1051

PMCID:: PMC3288642

Abstract Article PDF–523K

Select item 28366984.

Inherited genetic variant predisposes to aggressive but not indolent prostate cancer

Jianfeng Xu, Siqun Lilly Zheng, Sarah D. Isaacs, Kathleen E. Wiley, Fredrik Wiklund, Jielin Sun, A. Karim Kader, Ge Li, Lina D. Purcell, Seong-Tae Kim, Fang-Chi Hsu, Pär Stattin, Jonas Hugosson, Jan Adolfsson, Patrick C. Walsh, Jeffrey M. Trent, David Duggan, John Carpten, Henrik Grönberg, William B. Isaacs

Proc Natl Acad Sci U S A. 2010 Feb 2; 107(5): 2136–2140. Published online 2010 Jan 11. doi: 10.1073/pnas.0914061107

PMCID:: PMC2836698

Abstract Article PDF–260K

Select item 27686675.

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene

Ji Luo, Michael J. Emanuele, Danan Li, Chad J. Creighton, Michael R. Schlabach, Thomas F. Westbrook, Kwok-kin Wong, Stephen J. Elledge

Cell. Author manuscript; available in PMC 2009 Nov 29.

Published in final edited form as: Cell. 2009 May 29; 137(5): 835–848. doi: 10.1016/j.cell.2009.05.006

PMCID:: PMC2768667

Abstract Article PDF–4.0M

Select item 33337686.

The rhomboid protease family: a decade of progress on function and mechanism

Sinisa Urban, Seth W Dickey

Genome Biol. 2011; 12(10): 231. Published online 2011 Oct 27. doi: 10.1186/gb-2011-12-10-231

PMCID:: PMC3333768

Abstract Article PDF–2.4M

Select item 61666827.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 13561298.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Abstract Article PDF–438K

Select item 71699839.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x