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Items: 1 to 20 of 129

1.
Transcription recycling assays identify PAF1 as a driver for RNA Pol II recycling
Zhong Chen, William Hankey, Yue Zhao, Jeff Groth, Furong Huang, Hongyan Wang, Alexandre Rosa Campos, Jiaoti Huang, Robert G. Roeder, Qianben Wang
Nat Commun. 2021; 12: 6318. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26604-1
PMCID:
PMC8566496
AbstractArticlePDF–2.9M
2.
PAF1 Regulates Stem Cell Features of Pancreatic Cancer Cells, Independently of the PAF1 Complex, via Interactions with PHF5A and DDX3
Saswati Karmakar, Sanchita Rauth, Palanisamy Nallasamy, Naveenkumar Perumal, Rama Krishna Nimmakalaya, Frank Leon, Rohitesh Gupta, Srikanth Barkeer, Ramakanth Chirravuri Venkata, Venu Raman, Satyanarayana Rachagani, Moorthy P. Ponnusamy, Surinder K. Batra
Gastroenterology. Author manuscript; available in PMC 2021 Nov 1.
Published in final edited form as: Gastroenterology. 2020 Nov; 159(5): 1898–1915.e6. Published online 2020 Aug 8. doi: 10.1053/j.gastro.2020.07.053
PMCID:
PMC7680365
AbstractArticlePDF–3.1M
3.
PAF1 Regulation of Promoter-Proximal Pause Release via Enhancer Activation
Fei Xavier Chen, Peng Xie, Clayton K Collings, Kaixiang Cao, Yuki Aoi, Stacy A. Marshall, Emily J. Rendleman, Michal Ugarenko, Patrick A. Ozark, Anda Zhang, Ramin Shiekhattar, Edwin R. Smith, Michael Q. Zhang, Ali Shilatifard
Science. Author manuscript; available in PMC 2018 Jul 23.
Published in final edited form as: Science. 2017 Sep 22; 357(6357): 1294–1298. Published online 2017 Aug 31. doi: 10.1126/science.aan3269
PMCID:
PMC6055228
AbstractArticlePDF–760K
4.
Emerging Insights into the Roles of the Paf1 Complex in Gene Regulation
S. Branden Van Oss, Christine E. Cucinotta, Karen M. Arndt
Trends Biochem Sci. Author manuscript; available in PMC 2018 Oct 1.
Published in final edited form as: Trends Biochem Sci. 2017 Oct; 42(10): 788–798. Published online 2017 Sep 1. doi: 10.1016/j.tibs.2017.08.003
PMCID:
PMC5658044
AbstractArticlePDF–699K
5.
Overexpression of PD2 leads to increased tumorigenicity and metastasis in pancreatic ductal adenocarcinoma
Arokia Priyanka Vaz, Shonali Deb, Satyanarayana Rachagani, Parama Dey, Sakthivel Muniyan, Imayavaramban Lakshmanan, Saswati Karmakar, Lynette Smith, Sonny Johansson, Subodh Lele, Michel Ouellette, Moorthy P. Ponnusamy, Surinder K. Batra
Oncotarget. 2016 Jan 19; 7(3): 3317–3331. Published online 2015 Dec 12. doi: 10.18632/oncotarget.6580
PMCID:
PMC4823108
AbstractArticlePDF–5.8M
6.
Novel role of pancreatic differentiation 2 in facilitating self-renewal and drug resistance of pancreatic cancer stem cells
A P Vaz, M P Ponnusamy, S Rachagani, P Dey, A K Ganti, S K Batra
Br J Cancer. 2014 Jul 29; 111(3): 486–496. Published online 2014 Jul 8. doi: 10.1038/bjc.2014.152
PMCID:
PMC4119968
AbstractArticlePDF–3.1M
7.
PAFc, a Key Player in MLL-rearranged Leukemogenesis
Jiaying Tan, Andrew G. Muntean, Jay L. Hess
Oncotarget. 2010 Oct; 1(6): 461–465. Published online 2010 Oct 5. doi: 10.18632/oncotarget.181
PMCID:
PMC2965052
AbstractArticlePDF–589K
8.
The Human RNA Polymerase II-Associated Factor 1 (hPaf1): A New Regulator of Cell-Cycle Progression
Nicolas Moniaux, Christophe Nemos, Shonali Deb, Bing Zhu, Irena Dornreiter, Michael A. Hollingsworth, Surinder K. Batra
PLoS One. 2009; 4(9): e7077. Published online 2009 Sep 22. doi: 10.1371/journal.pone.0007077
PMCID:
PMC2740866
AbstractArticlePDF–1.3M
9.
NELF and PAF1C complexes are core transcriptional machineries controlling colon cancer stemness
Koji Aoki, Akari Nitta, Ayumi Igarashi
Oncogene. 2024; 43(8): 566–577. Published online 2024 Jan 5. doi: 10.1038/s41388-023-02930-0
PMCID:
PMC10873196
AbstractArticlePDF–8.0M
10.
Elevated PAF1-RAD52 axis confers chemoresistance to human cancers
Sanchita Rauth, Koelina Ganguly, Pranita Atri, Seema Parte, Rama Krishna Nimmakayala, Venkatesh Varadharaj, Palanisamy Nallasamy, Raghupathy Vengoji, Ayoola O. Ogunleye, Imayavaramban Lakshmanan, Ramakanth Chirravuri, Mika Bessho, Jesse L. Cox, Jason M. Foster, Geoffrey A. Talmon, Tadayoshi Bessho, Apar Kishor Ganti, Surinder K. Batra, Moorthy P. Ponnusamy
Cell Rep. Author manuscript; available in PMC 2023 Oct 23.
Published in final edited form as: Cell Rep. 2023 Feb 28; 42(2): 112043. Published online 2023 Jan 28. doi: 10.1016/j.celrep.2023.112043
PMCID:
PMC10374878
AbstractArticlePDF–3.9M
11.
PAF1 cooperates with YAP1 in metaplastic ducts to promote pancreatic cancer
Rama Krishna Nimmakayala, Ayoola O. Ogunleye, Seema Parte, Nivedeta Krishna Kumar, Pratima Raut, Venkatesh Varadharaj, Naveen Kumar Perumal, Palanisamy Nallasamy, Sanchita Rauth, Jesse L. Cox, Subodh M. Lele, Surinder K. Batra, Moorthy P. Ponnusamy
Cell Death Dis. 2022 Oct; 13(10): 839. Published online 2022 Oct 1. doi: 10.1038/s41419-022-05258-x
PMCID:
PMC9525575
AbstractArticlePDF–11M
12.
SUMO Modification of PAF1/PD2 Enables PML Interaction and Promotes Radiation Resistance in Pancreatic Ductal Adenocarcinoma
Sanchita Rauth, Saswati Karmakar, Ashu Shah, Parthasarathy Seshacharyulu, Rama Krishna Nimmakayala, Koelina Ganguly, Rakesh Bhatia, Sakthivel Muniyan, Sushil Kumar, Samikshan Dutta, Chi Lin, Kaustubh Datta, Surinder K. Batra, Moorthy P. Ponnusamy
Mol Cell Biol. 2021 Dec; 41(12): e00135-21. Prepublished online 2021 Sep 27. Published online 2021 Nov 22. doi: 10.1128/MCB.00135-21
PMCID:
PMC8608017
AbstractArticlePDF–6.8M
13.
A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair
Diana van den Heuvel, Cornelia G. Spruijt, Román González-Prieto, Angela Kragten, Michelle T. Paulsen, Di Zhou, Haoyu Wu, Katja Apelt, Yana van der Weegen, Kevin Yang, Madelon Dijk, Lucia Daxinger, Jurgen A. Marteijn, Alfred C. O. Vertegaal, Mats Ljungman, Michiel Vermeulen, Martijn S. Luijsterburg
Nat Commun. 2021; 12: 1342. Published online 2021 Feb 26. doi: 10.1038/s41467-021-21520-w
PMCID:
PMC7910549
AbstractArticlePDF–5.6M
14.
Novel role of PAF1 in attenuating radiosensitivity in cervical cancer by inhibiting IER5 transcription
Jing-Jie Zheng, Yue He, Yang Liu, Feng-Shuang Li, Zhen Cui, Xiao-Meng Du, Chun-Peng Wang, Yu-Mei Wu
Radiat Oncol. 2020; 15: 131. Published online 2020 May 29. doi: 10.1186/s13014-020-01580-w
PMCID:
PMC7257241
AbstractArticlePDF–4.5M
15.
A peptide encoded by circular form of LINC-PINT suppresses oncogenic transcriptional elongation in glioblastoma
Maolei Zhang, Kun Zhao, Xiaoping Xu, Yibing Yang, Sheng Yan, Ping Wei, Hui Liu, Jianbo Xu, Feizhe Xiao, Huangkai Zhou, Xuesong Yang, Nunu Huang, Jinglei Liu, Kejun He, Keping Xie, Gong Zhang, Suyun Huang, Nu Zhang
Nat Commun. 2018; 9: 4475. Published online 2018 Oct 26. doi: 10.1038/s41467-018-06862-2
PMCID:
PMC6203777
AbstractArticlePDF–4.1M
16.
hPaf1/PD2 interacts with OCT3/4 to promote self-renewal of ovarian cancer stem cells
Saswati Karmakar, Parthasarathy Seshacharyulu, Imayavaramban Lakshmanan, Arokia P. Vaz, Seema Chugh, Yuri M. Sheinin, Sidharth Mahapatra, Surinder K. Batra, Moorthy P. Ponnusamy
Oncotarget. 2017 Feb 28; 8(9): 14806–14820. Published online 2017 Jan 20. doi: 10.18632/oncotarget.14775
PMCID:
PMC5362445
AbstractArticlePDF–8.8M
17.
Structural insights into Paf1 complex assembly and histone binding
Xinlei Chu, Xiaohong Qin, Huisha Xu, Lei Li, Zheng Wang, Fengzhi Li, Xingqiao Xie, Hao Zhou, Yuequan Shen, Jiafu Long
Nucleic Acids Res. 2013 Dec; 41(22): 10619–10629. Published online 2013 Sep 14. doi: 10.1093/nar/gkt819
PMCID:
PMC3905892
AbstractArticlePDF–5.0M
18.
Viral Retasking of hBre1/RNF20 to Recruit hPaf1 for Transcriptional Activation
Gregory J. Fonseca, Michael J. Cohen, Anthony C. Nichols, John W. Barrett, Joe S. Mymryk
PLoS Pathog. 2013 Jun; 9(6): e1003411. Published online 2013 Jun 13. doi: 10.1371/journal.ppat.1003411
PMCID:
PMC3681745
AbstractArticlePDF–1.0M
19.
Suppression of the antiviral response by an influenza histone mimic
Ivan Marazzi, Jessica S. Y. Ho, Jaehoon Kim, Balaji Manicassamy, Scott Dewell, Randy A. Albrecht, Chris W. Seibert, Uwe Schaefer, Kate L. Jeffrey, Rab K. Prinjha, Kevin Lee, Adolfo García-Sastre, Robert G. Roeder, Alexander Tarakhovsky
Nature. Author manuscript; available in PMC 2013 Mar 22.
Published in final edited form as: Nature. 2012 Mar 14; 483(7390): 428–433. Published online 2012 Mar 14. doi: 10.1038/nature10892
PMCID:
PMC3598589
AbstractArticlePDF–2.4M
20.
A role for the RNA pol II–associated PAF complex in AID-induced immune diversification
Katharina L. Willmann, Sara Milosevic, Siim Pauklin, Kerstin-Maike Schmitz, Gopinath Rangam, Maria T. Simon, Sarah Maslen, Mark Skehel, Isabelle Robert, Vincent Heyer, Ebe Schiavo, Bernardo Reina-San-Martin, Svend K. Petersen-Mahrt
J Exp Med. 2012 Oct 22; 209(11): 2099–2111. doi: 10.1084/jem.20112145
PMCID:
PMC3478926
AbstractArticlePDF–2.8M

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