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Items: 1 to 20 of 45

1.
Elevated FAM134B expression induces radiation-sensitive in hepatocellular carcinoma
Binhui Xie, Yuankang Xie, Cuifu Fang, Baiyin Zhong, Rong Ye, Jianhong Zhang, Qingquan Liu, Heping Li
BMC Cancer. 2023; 23: 671. Published online 2023 Jul 17. doi: 10.1186/s12885-023-11030-x
PMCID:
PMC10353116
AbstractArticlePDF–3.1M
2.
FAM134B-Mediated ER-phagy Upregulation Attenuates AGEs-Induced Apoptosis and Senescence in Human Nucleus Pulposus Cells
Rongjin Luo, Shuai Li, Gaocai Li, Saideng Lu, Weifeng Zhang, Hui Liu, Jie Lei, Liang Ma, Wencan Ke, Zhiwei Liao, Bingjin Wang, Yu Song, Kun Wang, Yukun Zhang, Cao Yang
Oxid Med Cell Longev. 2021; 2021: 3843145. Published online 2021 Aug 5. doi: 10.1155/2021/3843145
PMCID:
PMC8363461
AbstractArticlePDF–4.0M
3.
Overexpression of family with sequence similarity 134, member B (FAM134B) in colon cancers and its tumor suppressive properties in vitro
Katherine Ting-Wei Lee, Farhadul Islam, Jelena Vider, Jeremy Martin, Anna Chruścik, Cu-Tai Lu, Vinod Gopalan, Alfred King-yin Lam
Cancer Biol Ther. 2020; 21(10): 954–962. Published online 2020 Aug 28. doi: 10.1080/15384047.2020.1810535
PMCID:
PMC7583494
AbstractArticlePDF–2.1M
4.
Excessive ER-phagy mediated by the autophagy receptor FAM134B results in ER stress, the unfolded protein response, and cell death in HeLa cells
Yangjie Liao, Bo Duan, Yufei Zhang, Xinmin Zhang, Bin Xia
J Biol Chem. 2019 Dec 27; 294(52): 20009–20023. Published online 2019 Nov 20. doi: 10.1074/jbc.RA119.008709
PMCID:
PMC6937584
AbstractArticlePDF–5.4M
5.
Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy
Ramachandra M. Bhaskara, Paolo Grumati, Javier Garcia-Pardo, Sissy Kalayil, Adriana Covarrubias-Pinto, Wenbo Chen, Mikhail Kudryashev, Ivan Dikic, Gerhard Hummer
Nat Commun. 2019; 10: 2370. Published online 2019 May 30. doi: 10.1038/s41467-019-10345-3
PMCID:
PMC6542808
AbstractArticlePDF–7.1M
6.
FAM134B induces tumorigenesis and epithelial‐to‐mesenchymal transition via Akt signaling in hepatocellular carcinoma
Zhao‐qi Zhang, Jin Chen, Wan‐qiu Huang, Deng Ning, Qiu‐meng Liu, Chao Wang, Long Zhang, Li Ren, Liang Chu, Hui‐fang Liang, Hai‐ning Fan, Bi‐xiang Zhang, Xiao‐ping Chen
Mol Oncol. 2019 Apr; 13(4): 792–810. Published online 2019 Jan 24. doi: 10.1002/1878-0261.12429
PMCID:
PMC6441892
AbstractArticlePDF–2.4M
7.
Dengue and Zika viruses subvert reticulophagy by NS2B3-mediated cleavage of FAM134B
Nicholas J. Lennemann, Carolyn B. Coyne
Autophagy. 2017; 13(2): 322–332. Published online 2017 Jan 19. doi: 10.1080/15548627.2016.1265192
PMCID:
PMC5324851
AbstractArticlePDF–1.2M
8.
Identification of Novel FAM134B (JK1) Mutations in Oesophageal Squamous Cell Carcinoma
Md. Hakimul Haque, Vinod Gopalan, Kwok-wah Chan, Muhammad J. A. Shiddiky, Robert Anthony Smith, Alfred King-yin Lam
Sci Rep. 2016; 6: 29173. Published online 2016 Jul 4. doi: 10.1038/srep29173
PMCID:
PMC4931577
AbstractArticlePDF–807K
9.
Mutation in FAM134B causing severe hereditary sensory neuropathy
Sinead M Murphy, Gabrielle L Davidson, Sebastian Brandner, Henry Houlden, Mary M Reilly
J Neurol Neurosurg Psychiatry. Author manuscript; available in PMC 2013 Jul 24.
Published in final edited form as: J Neurol Neurosurg Psychiatry. 2012 Jan; 83(1): 119–120. Published online 2010 Nov 28. doi: 10.1136/jnnp.2010.228965
PMCID:
PMC3721196
AbstractArticlePDF–607K
10.
A regulatory circuit comprising the CBP and SIRT7 regulates FAM134B-mediated ER-phagy
Xinyi Wang, Xiao Jiang, Boran Li, Jiahua Zheng, Jiansheng Guo, Lei Gao, Mengjie Du, Xialian Weng, Lin Li, She Chen, Jingzi Zhang, Lei Fang, Ting Liu, Liang Wang, Wei Liu, Dante Neculai, Qiming Sun
J Cell Biol. 2023 May 1; 222(5): e202201068. Published online 2023 Apr 12. doi: 10.1083/jcb.202201068
PMCID:
PMC10103787
AbstractArticlePDF–6.2M
11.
Differential expression of full-length and NH2 terminally truncated FAM134B isoforms in normal physiology and cancer
Umur Keles, Evin Iscan, Huriye Erbak Yilmaz, Gökhan Karakülah, Aslı Suner, Erhan Bal, Nilgun Tasdemir, Ayse Derya Cavga, Umut Ekin, Zeynep Mutlu, Sila Kahyaoglu, Muhittin A. Serdar, Nese Atabey, Mehmet Ozturk
Am J Physiol Gastrointest Liver Physiol. 2020 Dec 1; 319(6): G733–G747. Published online 2020 Oct 14. doi: 10.1152/ajpgi.00094.2020
PMCID:
PMC7864244
AbstractArticle
12.
Novel exomic rare variants associated with venous thrombosis
Hiroshi Deguchi, Meenal Shukla, Mohammed Hayat, Ali Torkamani, Darlene J. Elias, John H. Griffin
Br J Haematol. Author manuscript; available in PMC 2020 Dec 11.
Published in final edited form as: Br J Haematol. 2020 Sep; 190(5): 783–786. Published online 2020 Mar 30. doi: 10.1111/bjh.16613
PMCID:
PMC7732677
AbstractArticlePDF–108K
13.
FAM134B oligomerization drives endoplasmic reticulum membrane scission for ER‐phagy
Xiao Jiang, Xinyi Wang, Xianming Ding, Mengjie Du, Boran Li, Xialian Weng, Jingzi Zhang, Lin Li, Rui Tian, Qi Zhu, She Chen, Liang Wang, Wei Liu, Lei Fang, Dante Neculai, Qiming Sun
EMBO J. 2020 Mar 2; 39(5): e102608. Published online 2020 Jan 13. doi: 10.15252/embj.2019102608
PMCID:
PMC7049798
AbstractArticlePDF–3.1M
14.
A selective ER‐phagy exerts procollagen quality control via a Calnexin‐FAM134B complex
Alison Forrester, Chiara De Leonibus, Paolo Grumati, Elisa Fasana, Marilina Piemontese, Leopoldo Staiano, Ilaria Fregno, Andrea Raimondi, Alessandro Marazza, Gemma Bruno, Maria Iavazzo, Daniela Intartaglia, Marta Seczynska, Eelco van Anken, Ivan Conte, Maria Antonietta De Matteis, Ivan Dikic, Maurizio Molinari, Carmine Settembre
EMBO J. 2019 Jan 15; 38(2): e99847. Published online 2018 Dec 17. doi: 10.15252/embj.201899847
PMCID:
PMC6331724
AbstractArticlePDF–3.6M
15.
Genetic analysis of an allergic rhinitis cohort reveals an intercellular epistasis between FAM134B and CD39
Rossella Melchiotti, Kia Joo Puan, Anand Kumar Andiappan, Tuang Yeow Poh, Mireille Starke, Li Zhuang, Kerstin Petsch, Tuck Siong Lai, Fook Tim Chew, Anis Larbi, De Yun Wang, Michael Poidinger, Olaf Rotzschke
BMC Med Genet. 2014; 15: 73. Published online 2014 Jun 27. doi: 10.1186/1471-2350-15-73
PMCID:
PMC4094447
AbstractArticlePDF–1.0M
16.
SARS-CoV-2 ORF3a induces RETREG1/FAM134B-dependent reticulophagy and triggers sequential ER stress and inflammatory responses during SARS-CoV-2 infection
Xiaolin Zhang, Ziwei Yang, Ting Pan, Xubing Long, Qinqin Sun, Pei-Hui Wang, Xiaojuan Li, Ersheng Kuang
Autophagy. 2022; 18(11): 2576–2592. Published online 2022 Mar 3. doi: 10.1080/15548627.2022.2039992
PMCID:
PMC9629087
AbstractArticlePDF–2.4M
17.
Genomics Links Inflammation With Neurocognitive Impairment in Children Living With Human Immunodeficiency Virus Type-1
Pratima Rawat, Sean S Brummel, Kumud K Singh, Jihoon Kim, Kelly A Frazer, Sharon Nichols, George R Seage, III, Paige L Williams, Russell B Van Dyke, Olivier Harismendy, Rodney N Trout, Stephen A Spector
J Infect Dis. 2021 Sep 1; 224(5): 870–880. Published online 2020 Dec 29. doi: 10.1093/infdis/jiaa792
PMCID:
PMC8408770
AbstractArticlePDF–2.3M
18.
RETREG1/FAM134B mediated autophagosomal degradation of AMFR/GP78 and OPA1 —a dual organellar turnover mechanism
Debdatto Mookherjee, Subhrangshu Das, Rukmini Mukherjee, Manindra Bera, Swadhin Chandra Jana, Saikat Chakrabarti, Oishee Chakrabarti
Autophagy. 2021; 17(7): 1729–1752. Published online 2020 Jul 1. doi: 10.1080/15548627.2020.1783118
PMCID:
PMC8354597
AbstractArticlePDF–25M
19.
MiT/TFE factors control ER‐phagy via transcriptional regulation of FAM134B
Laura Cinque, Chiara De Leonibus, Maria Iavazzo, Natalie Krahmer, Daniela Intartaglia, Francesco Giuseppe Salierno, Rossella De Cegli, Chiara Di Malta, Maria Svelto, Carmela Lanzara, Marianna Maddaluno, Luca Giorgio Wanderlingh, Antje K Huebner, Marcella Cesana, Florian Bonn, Elena Polishchuk, Christian A Hübner, Ivan Conte, Ivan Dikic, Matthias Mann, Andrea Ballabio, Francesca Sacco, Paolo Grumati, Carmine Settembre
EMBO J. 2020 Sep 1; 39(17): e105696. Published online 2020 Jul 27. doi: 10.15252/embj.2020105696
PMCID:
PMC7459426
AbstractArticlePDF–4.1M
20.
Repurposing Brigatinib for the Treatment of Colorectal Cancer Based on Inhibition of ER-phagy
Zhe Zhang, Wei Gao, Li Zhou, Yan Chen, Siyuan Qin, Lu Zhang, Jiayang Liu, Yujia He, Yunlong Lei, Hai-Ning Chen, Junhong Han, Zong-Guang Zhou, Edouard C. Nice, Changlong Li, Canhua Huang, Xiawei Wei
Theranostics. 2019; 9(17): 4878–4892. Published online 2019 Jul 9. doi: 10.7150/thno.36254
PMCID:
PMC6691391
AbstractArticlePDF–3.5M

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