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Select item 111738921.

The Human Paraoxonase 2: An Optimized Procedure for Refolding and Stabilization Facilitates Enzyme Analyses and a Proteomics Approach

Eros A. Lampitella, Maria Marone, Nagendra S. K. Achanta, Elena Porzio, Francesco Trepiccione, Giuseppe Manco

Molecules. 2024 Jun; 29(11): 2434. Published online 2024 May 22. doi: 10.3390/molecules29112434

PMCID:: PMC11173892

Abstract Article PDF–3.7M

Select item 108867632.

Contribution of the Paraoxonase-2 Enzyme to Cancer Cell Metabolism and Phenotypes

Roberto Campagna, Emma Nicol Serritelli, Eleonora Salvolini, Valentina Schiavoni, Monia Cecati, Davide Sartini, Valentina Pozzi, Monica Emanuelli

Biomolecules. 2024 Feb; 14(2): 208. Published online 2024 Feb 9. doi: 10.3390/biom14020208

PMCID:: PMC10886763

Abstract Article PDF–1.7M

Select item 98487043.

Interactome of Paraoxonase PON2 Reveals New Pathways for Tumor Growth Regulation

V. D. Karlov, N. B. Pestov, M. I. Shakhparonov, T. V. Korneenko

Dokl Biochem Biophys. 2023; 508(1): 31–36. Published online 2023 Jan 18. doi: 10.1134/S1607672922700089

PMCID:: PMC9848704

Abstract Article PDF–603K

Select item 98204984.

Role Played by Paraoxonase-2 Enzyme in Cell Viability, Proliferation and Sensitivity to Chemotherapy of Oral Squamous Cell Carcinoma Cell Lines

Roberto Campagna, Alessia Belloni, Valentina Pozzi, Alessia Salvucci, Valentina Notarstefano, Lucrezia Togni, Marco Mascitti, Davide Sartini, Elisabetta Giorgini, Eleonora Salvolini, Andrea Santarelli, Lorenzo Lo Muzio, Monica Emanuelli

Int J Mol Sci. 2023 Jan; 24(1): 338. Published online 2022 Dec 25. doi: 10.3390/ijms24010338

PMCID:: PMC9820498

Abstract Article PDF–2.2M

Select item 89201965.

Airway epithelial Paraoxonase-2 in obese asthma

Daniel Efrain Winnica, Anthony Monzon, Shuyu Ye, Eszter K. Vladar, Maxwell Saal, Riley Cooney, Cuining Liu, Sunita Sharma, Fernando Holguin

PLoS One. 2022; 17(3): e0261504. Published online 2022 Mar 14. doi: 10.1371/journal.pone.0261504

PMCID:: PMC8920196

Abstract Article PDF–2.0M

Select item 87211876.

Insights into the role of paraoxonase 2 in human pathophysiology

Fauzia Parween, Rinkoo Devi Gupta

J Biosci. 2022; 47(1): 4. Published online 2022 Jan 3. doi: 10.1007/s12038-021-00234-7

PMCID:: PMC8721187

Abstract Article PDF–1.8M

Select item 69530217.

Effect of High Glucose-Induced Oxidative Stress on Paraoxonase 2 Expression and Activity in Caco-2 Cells

Camilla Morresi, Laura Cianfruglia, Davide Sartini, Monia Cecati, Stefania Fumarola, Monica Emanuelli, Tatiana Armeni, Gianna Ferretti, Tiziana Bacchetti

Cells. 2019 Dec; 8(12): 1616. Published online 2019 Dec 11. doi: 10.3390/cells8121616

PMCID:: PMC6953021

Abstract Article PDF–1.5M

Select item 58475608.

Paraoxonase 2 overexpression inhibits tumor development in a mouse model of ovarian cancer

Asokan Devarajan, Feng Su, Victor Grijalva, Meghna Yalamanchi, Ashna Yalamanchi, Feng Gao, Hannah Trost, Josephine Nwokedi, Gina Farias-Eisner, Robin Farias-Eisner, Alan M. Fogelman, Srinivasa T Reddy

Cell Death Dis. 2018 Mar; 9(3): 392. Published online 2018 Mar 12. doi: 10.1038/s41419-018-0395-2

PMCID:: PMC5847560

Abstract Article PDF–1.6M

Select item 54386919.

Exploring the role of Paraoxonase-2 in bladder cancer: analyses performed on tissue samples, urines and cell culturess

Tiziana Bacchetti, Davide Sartini, Valentina Pozzi, Tiziana Cacciamani, Gianna Ferretti, Monica Emanuelli

Oncotarget. 2017 Apr 25; 8(17): 28785–28795. Published online 2017 Feb 24. doi: 10.18632/oncotarget.15674

PMCID:: PMC5438691

Abstract Article PDF–2.4M

Select item 523946010.

The anti-apoptotic PON2 protein is Wnt/β-catenin-regulated and correlates with radiotherapy resistance in OSCC patients

Maximilian Krüger, Julianna Amort, Petra Wilgenbus, Johanna P. Helmstädter, Irina Grechowa, Julia Ebert, Stefan Tenzer, Maximilian Moergel, Ines Witte, Sven Horke

Oncotarget. 2016 Aug 9; 7(32): 51082–51095. Published online 2016 Apr 26. doi: 10.18632/oncotarget.9013

PMCID:: PMC5239460

Abstract Article PDF–1.8M

Select item 502785911.

Association Between Paraoxonase 2 Ser311Cys Polymorphism and Coronary Heart Disease Risk: A Meta-Analysis

Min-Li Chen, Hua Zhao, Ning Liao, Zheng-Fu Xie

Med Sci Monit. 2016; 22: 3196–3201. Published online 2016 Sep 9. doi: 10.12659/MSM.896601

PMCID:: PMC5027859

Abstract Article PDF–428K

Select item 468434012.

An Engineered Version of Human PON2 Opens the Way to Understand the Role of Its Post-Translational Modifications in Modulating Catalytic Activity

Luigi Mandrich, Mariangela Cerreta, Giuseppe Manco

PLoS One. 2015; 10(12): e0144579. Published online 2015 Dec 10. doi: 10.1371/journal.pone.0144579

PMCID:: PMC4684340

Abstract Article PDF–1.2M

Select item 453467113.

Novel Paraoxonase 2-Dependent Mechanism Mediating the Biological Effects of the Pseudomonas aeruginosa Quorum-Sensing Molecule N-(3-Oxo-Dodecanoyl)-l-Homoserine Lactone

Sven Horke, Junhui Xiao, Eva-Maria Schütz, Gerald L. Kramer, Petra Wilgenbus, Ines Witte, Moritz Selbach, John F. Teiber

Infect Immun. 2015 Sep; 83(9): 3369–3380. Prepublished online 2015 Jun 8. Published online 2015 Aug 12. doi: 10.1128/IAI.00141-15

PMCID:: PMC4534671

Abstract Article PDF–2.2M

Select item 401601914.

Paraoxonase 2 Protein Is Spatially Expressed in the Human Placenta and Selectively Reduced in Labour

Samy Alwarfaly, Akrem Abdulsid, Kevin Hanretty, Fiona Lyall

PLoS One. 2014; 9(5): e96754. Published online 2014 May 9. doi: 10.1371/journal.pone.0096754

PMCID:: PMC4016019

Abstract Article PDF–1.0M

Select item 346855615.

Antioxidative properties of paraoxonase 2 in intestinal epithelial cells

Louis-Philippe Précourt, Valérie Marcil, Thierry Ntimbane, Rame Taha, Jean-Claude Lavoie, Edgard Delvin, Ernest G. Seidman, Jean-François Beaulieu, Emile Levy

Am J Physiol Gastrointest Liver Physiol. 2012 Sep 1; 303(5): G623–G634. Published online 2012 Jun 28. doi: 10.1152/ajpgi.00039.2012

PMCID:: PMC3468556

Abstract Article

Select item 307728716.

Beyond reduction of atherosclerosis: PON2 provides apoptosis resistance and stabilizes tumor cells

I Witte, S Altenhöfer, P Wilgenbus, J Amort, A M Clement, A Pautz, H Li, U Förstermann, S Horke

Cell Death Dis. 2011 Jan; 2(1): e112. Published online 2011 Jan 13. doi: 10.1038/cddis.2010.91

PMCID:: PMC3077287

Abstract Article PDF–922K

Select item 303052817.

Association analysis of PON2 genetic variants with serum paraoxonase activity and systemic lupus erythematosus

Sudeshna Dasgupta, F Yesim Demirci, Amy S Dressen, Amy H Kao, Elisa Y Rhew, Rosalind Ramsey-Goldman, Susan Manzi, Candace M Kammerer, M Ilyas Kamboh

BMC Med Genet. 2011; 12: 7. Published online 2011 Jan 11. doi: 10.1186/1471-2350-12-7

PMCID:: PMC3030528

Abstract Article PDF–357K

Select item 291567518.

One Enzyme, Two Functions: PON2 PREVENTS MITOCHONDRIAL SUPEROXIDE FORMATION AND APOPTOSIS INDEPENDENT FROM ITS LACTONASE ACTIVITY

Sebastian Altenhöfer, Ines Witte, John F. Teiber, Petra Wilgenbus, Andrea Pautz, Huige Li, Andreas Daiber, Heidrun Witan, Albrecht M. Clement, Ulrich Förstermann, Sven Horke

J Biol Chem. 2010 Aug 6; 285(32): 24398–24403. Published online 2010 Jun 8. doi: 10.1074/jbc.M110.118604

PMCID:: PMC2915675

Abstract Article PDF–834K

Select item 279098619.

A Common Mutation in Paraoxonase-2 Results in Impaired Lactonase Activity

David A. Stoltz, Egon A. Ozer, Thomas J. Recker, Miriam Estin, Xia Yang, Diana M. Shih, Aldons J. Lusis, Joseph Zabner

J Biol Chem. 2009 Dec 18; 284(51): 35564–35571. Published online 2009 Oct 19. doi: 10.1074/jbc.M109.051706

PMCID:: PMC2790986

Abstract Article PDF–1.7M

Select item 276915920.

Effect of Quercetin on Paraoxonase 2 Levels in RAW264.7 Macrophages and in Human Monocytes––Role of Quercetin Metabolism

Christine Boesch-Saadatmandi, Renata Toedter Pospissil, Anne-Christin Graeser, Raffaella Canali, Inka Boomgaarden, Frank Doering, Siegfried Wolffram, Sarah Egert, Manfred James Mueller, Gerald Rimbach

Int J Mol Sci. 2009 Sep; 10(9): 4168–4177. Published online 2009 Sep 23. doi: 10.3390/ijms10094168