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Select item 73396381.

Septin4 regulates endoplasmic reticulum stress and apoptosis in melatonin-induced osteoblasts

Lin Tao, Sichao Zhao, Zhengbo Tao, Kaicheng Wen, Siming Zhou, Wacili Da, Yue Zhu

Mol Med Rep. 2020 Aug; 22(2): 1179–1186. Published online 2020 Jun 15. doi: 10.3892/mmr.2020.11228

PMCID:: PMC7339638

Abstract Article PDF–907K

Select item 60382922.

Untangling the Tauopathy for Alzheimer’s disease and parkinsonism

Hui-Yun Chang, Tzu-Kang Sang, Ann-Shyn Chiang

J Biomed Sci. 2018; 25: 54. Published online 2018 Jul 10. doi: 10.1186/s12929-018-0457-x

PMCID:: PMC6038292

Abstract Article PDF–985K

Select item 43407373.

Septin4_i1 Regulates Apoptosis in Hepatic Stellate Cells through Peroxisome Proliferator-Activated Receptor-γ/Akt/B-Cell Lymphoma 2 Pathway

Dandan Zhu, Jianxin Wang, Xiaolei Sun, Jinling Chen, Yinong Duan, Jing Pan, Tianhua Xu, Yongwei Qin, Xingxin He, Caiqun Huang

J Histochem Cytochem. 2015 Mar; 63(3): 163–169. doi: 10.1369/0022155414567230

PMCID:: PMC4340737

Abstract Article PDF–555K

Select item 100530234.

The ARTS of p53-dependent mitochondrial apoptosis

Qian Hao, Jiaxiang Chen, Hua Lu, Xiang Zhou

J Mol Cell Biol. 2022 Oct; 14(10): mjac074. Published online 2022 Dec 24. doi: 10.1093/jmcb/mjac074

PMCID:: PMC10053023

Abstract Article PDF–642K

Select item 79047755.

p53 induces ARTS to promote mitochondrial apoptosis

Qian Hao, Jiaxiang Chen, Junming Liao, Yingdan Huang, Yu Gan, Sarit Larisch, Shelya X. Zeng, Hua Lu, Xiang Zhou

Cell Death Dis. 2021 Feb; 12(2): 204. Published online 2021 Feb 24. doi: 10.1038/s41419-021-03463-8

PMCID:: PMC7904775

Abstract Article PDF–2.4M

Select item 82606626.

Septin4 promotes cardiomyocytes apoptosis by enhancing the VHL-mediated degradation of HIF-1α

Shaojun Wu, Ying Zhang, Shilong You, Saien Lu, Naijin Zhang, Yingxian Sun

Cell Death Discov. 2021; 7: 172. Published online 2021 Jul 6. doi: 10.1038/s41420-021-00563-4

PMCID:: PMC8260662

Abstract Article PDF–3.6M

Select item 69510917.

Role of WW domain E3 ubiquitin protein ligase 2 in modulating ubiquitination and Degradation of Septin4 in oxidative stress endothelial injury

Naijin Zhang, Ying Zhang, Boquan Wu, Shilong You, Yingxian Sun

Redox Biol. 2020 Feb; 30: 101419. Published online 2020 Jan 2. doi: 10.1016/j.redox.2019.101419

PMCID:: PMC6951091

Abstract Article PDF–4.2M

Select item 43616208.

SEPT12/SPAG4/LAMINB1 Complexes Are Required for Maintaining the Integrity of the Nuclear Envelope in Postmeiotic Male Germ Cells

Chung-Hsin Yeh, Pao-Lin Kuo, Ya-Yun Wang, Ying-Yu Wu, Mei-Feng Chen, Ding-Yen Lin, Tsung-Hsuan Lai, Han-Sun Chiang, Ying-Hung Lin

PLoS One. 2015; 10(3): e0120722. Published online 2015 Mar 16. doi: 10.1371/journal.pone.0120722

PMCID:: PMC4361620

Abstract Article PDF–690K

Select item 11339539.

Human septin–septin interactions as a prerequisite for targeting septin complexes in the cytosol

Constantino Martínez, Miguel A. Sanjuan, Judith A. Dent, Lars Karlsson, Jerry Ware

Biochem J. 2004 Sep 15; 382(Pt 3): 783–791. Prepublished online 2004 Jun 23. Published online 2004 Sep 7. doi: 10.1042/BJ20040372

PMCID:: PMC1133953

Abstract Article PDF–485K

Select item 301764410.

ARTS and Siah Collaborate in a Pathway for XIAP Degradation

Jason B. Garrison, Ricardo G. Correa, Motti Gerlic, Kenneth W. Yip, Andreas Krieg, Craig M. Tamble, Ranxin Shi, Kate Welsh, Srinivas Duggineni, Ziwei Huang, Keqin Ren, Chunying Du, John C. Reed

Mol Cell. Author manuscript; available in PMC 2012 Jan 7.

Published in final edited form as: Mol Cell. 2011 Jan 7; 41(1): 107–116. Published online 2010 Dec 23. doi: 10.1016/j.molcel.2010.12.002

PMCID:: PMC3017644

Abstract Article PDF–1.4M

Select item 326349211.

The IAP-antagonist ARTS initiates caspase activation upstream of cytochrome C and SMAC/Diablo

N Edison, D Zuri, I Maniv, B Bornstein, T Lev, Y Gottfried, S Kemeny, M Garcia-Fernandez, J Kagan, S Larisch

Cell Death Differ. 2012 Feb; 19(2): 356–368. Published online 2011 Aug 26. doi: 10.1038/cdd.2011.112

PMCID:: PMC3263492

Abstract Article PDF–1005K

Select item 39106512.

The mitochondrial ARTS protein promotes apoptosis through targeting XIAP

Yossi Gottfried, Asaf Rotem, Rona Lotan, Hermann Steller, Sarit Larisch

EMBO J. 2004 Apr 7; 23(7): 1627–1635. Published online 2004 Mar 18. doi: 10.1038/sj.emboj.7600155

PMCID:: PMC391065

Abstract Article PDF–404K

Select item 363688713.

Identification of a Novel Anti-apoptotic E3 Ubiquitin Ligase That Ubiquitinates Antagonists of Inhibitor of Apoptosis Proteins SMAC, HtrA2, and ARTS

Jung-bin Kim, So Youn Kim, Byeong Mo Kim, Hunjin Lee, Insook Kim, Jeanho Yun, Yejin Jo, Taeheun Oh, Yongsam Jo, Hee-Don Chae, Deug Y. Shin

J Biol Chem. 2013 Apr 26; 288(17): 12014–12021. Published online 2013 Mar 11. doi: 10.1074/jbc.M112.436113

PMCID:: PMC3636887

Abstract Article PDF–1.8M

Select item 566755514.

Degradation of Bcl-2 by XIAP and ARTS promotes apoptosis

Natalia Edison, Yael Curtz, Nicole Paland, Dana Mamriev, Nicolas Chorubczyk, Tali Haviv Reingewertz, Nir Kfir, David Morgenstern, Meital Kupervaser, Juliana Kagan, Hyoung Tae Kim, Sarit Larisch

Cell Rep. Author manuscript; available in PMC 2017 Nov 2.

Published in final edited form as: Cell Rep. 2017 Oct 10; 21(2): 442–454. doi: 10.1016/j.celrep.2017.09.052

PMCID:: PMC5667555

Abstract Article PDF–2.7M

Select item 372393015.

Meta-analysis identifies four new loci associated with testicular germ cell tumor

Charles C. Chung, Peter A. Kanetsky, Zhaoming Wang, Michelle A. T. Hildebrandt, Roelof Koster, Rolf I. Skotheim, Christian P. Kratz, Clare Turnbull, Victoria K. Cortessis, Anne C. Bakken, D. Timothy Bishop, Michael B. Cook, R. Loren Erickson, Sophie D. Fosså, Kevin B. Jacobs, Larissa A. Korde, Sigrid M. Kraggerud, Ragnhild A. Lothe, Jennifer T. Loud, Nazneen Rahman, Eila C. Skinner, Duncan C. Thomas, Xifeng Wu, Meredith Yeager, Fredrick R. Schumacher, Mark H. Greene, Stephen M. Schwartz, Katherine A. McGlynn, Stephen J. Chanock, Katherine L. Nathanson

Nat Genet. Author manuscript; available in PMC 2013 Dec 1.

Published in final edited form as: Nat Genet. 2013 Jun; 45(6): 680–685. Published online 2013 May 12. doi: 10.1038/ng.2634

PMCID:: PMC3723930

Abstract Article PDF–1.0M

Select item 541782516.

Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome

Xiaorong Wang, Peter Cimermancic, Clinton Yu, Andreas Schweitzer, Nikita Chopra, James L. Engel, Charles Greenberg, Alexander S. Huszagh, Florian Beck, Eri Sakata, Yingying Yang, Eric J. Novitsky, Alexander Leitner, Paolo Nanni, Abdullah Kahraman, Xing Guo, Jack E. Dixon, Scott D. Rychnovsky, Ruedi Aebersold, Wolfgang Baumeister, Andrej Sali, Lan Huang

Mol Cell Proteomics. 2017 May; 16(5): 840–854. Published online 2017 Mar 14. doi: 10.1074/mcp.M116.065326

PMCID:: PMC5417825

Abstract Article PDF–3.2M

Select item 261043417.

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage

Michael C. Zody, Manuel Garber, David J. Adams, Ted Sharpe, Jennifer Harrow, James R. Lupski, Christine Nicholson, Steven M. Searle, Laurens Wilming, Sarah K. Young, Amr Abouelleil, Nicole R. Allen, Weimin Bi, Toby Bloom, Mark L. Borowsky, Boris E. Bugalter, Jonathan Butler, Jean L. Chang, Chao-Kung Chen, April Cook, Benjamin Corum, Christina A. Cuomo, Pieter J. de Jong, David DeCaprio, Ken Dewar, Michael FitzGerald, James Gilbert, Richard Gibson, Sante Gnerre, Steven Goldstein, Darren V. Grafham, Russell Grocock, Nabil Hafez, Daniel S. Hagopian, Elizabeth Hart, Catherine Hosage Norman, Sean Humphray, David B. Jaffe, Matt Jones, Michael Kamal, Varsha K. Khodiyar, Kurt LaButti, Gavin Laird, Jessica Lehoczky, Xiaohong Liu, Tashi Lokyitsang, Jane Loveland, Annie Lui, Pendexter Macdonald, John E. Major, Lucy Matthews, Evan Mauceli, Steven A. McCarroll, Atanas H. Mihalev, Jonathan Mudge, Cindy Nguyen, Robert Nicol, Sinéad B. O'Leary, Kazutoyo Osoegawa, David C. Schwartz, Charles Shaw-Smith, Pawel Stankiewicz, Charles Steward, David Swarbreck, Vijay Venkataraman, Charles A. Whittaker, Xiaoping Yang, Andrew R. Zimmer, Allan Bradley, Tim Hubbard, Bruce W. Birren, Jane Rogers, Eric S. Lander, Chad Nusbaum

Nature. Author manuscript; available in PMC 2008 Dec 29.

Published in final edited form as: Nature. 2006 Apr 20; 440(7087): 1045–1049. doi: 10.1038/nature04689

PMCID:: PMC2610434

Abstract Article PDF–947K

Select item 722681218.

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex

Marissa M. Minor, F. Blaine Hollinger, Adrienne L. McNees, Sung Yun Jung, Antrix Jain, Joseph M. Hyser, Karl-Dimiter Bissig, Betty L. Slagle

Cells. 2020 Apr; 9(4): 834. Published online 2020 Mar 30. doi: 10.3390/cells9040834

PMCID:: PMC7226812

Abstract Article PDF–2.3M

Select item 316943219.

Protein interactome reveals converging molecular pathways among autism disorders

Yasunari Sakai, Chad A. Shaw, Brian C. Dawson, Diana V. Dugas, Zaina Al-Mohtaseb, David E. Hill, Huda Y. Zoghbi

Sci Transl Med. Author manuscript; available in PMC 2011 Dec 8.

Published in final edited form as: Sci Transl Med. 2011 Jun 8; 3(86): 86ra49. doi: 10.1126/scitranslmed.3002166

PMCID:: PMC3169432

Abstract Article PDF–6.0M

Select item 294347620.

Genetic Variants in Nuclear-Encoded Mitochondrial Genes Influence AIDS Progression

Sher L. Hendrickson, James A. Lautenberger, Leslie Wei Chinn, Michael Malasky, Efe Sezgin, Lawrence A. Kingsley, James J. Goedert, Gregory D. Kirk, Edward D. Gomperts, Susan P. Buchbinder, Jennifer L. Troyer, Stephen J. O'Brien

PLoS One. 2010; 5(9): e12862. Published online 2010 Sep 21. doi: 10.1371/journal.pone.0012862

PMCID:: PMC2943476

Abstract Article PDF–461K

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