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Items: 1 to 20 of 55

1.
PHF2 regulates homology-directed DNA repair by controlling the resection of DNA double strand breaks
Ignacio Alonso-de Vega, Maria Cristina Paz-Cabrera, Magdalena B Rother, Wouter W Wiegant, Cintia Checa-Rodríguez, Juan Ramón Hernández-Fernaud, Pablo Huertas, Raimundo Freire, Haico van Attikum, Veronique A J Smits
Nucleic Acids Res. 2020 May 21; 48(9): 4915–4927. Published online 2020 Mar 30. doi: 10.1093/nar/gkaa196
PMCID:
PMC7229830
AbstractArticlePDF–8.7M
2.
Palmitoylation-driven PHF2 ubiquitination remodels lipid metabolism through the SREBP1c axis in hepatocellular carcinoma
Do-Won Jeong, Jong-Wan Park, Kyeong Seog Kim, Jiyoung Kim, June Huh, Jieun Seo, Ye Lee Kim, Joo-Youn Cho, Kwang-Woong Lee, Junji Fukuda, Yang-Sook Chun
Nat Commun. 2023; 14: 6370. Published online 2023 Oct 12. doi: 10.1038/s41467-023-42170-0
PMCID:
PMC10570296
AbstractArticlePDF–3.7M
3.
MiR-221 Promotes Hepatocellular Carcinoma Cells Migration via Targeting PHF2
Yi Fu, Mingyan Liu, Fengxia Li, Li Qian, Ping Zhang, Fengwei Lv, Wenting Cheng, Ruixing Hou
Biomed Res Int. 2019; 2019: 4371405. Published online 2019 May 12. doi: 10.1155/2019/4371405
PMCID:
PMC6535842
AbstractArticlePDF–3.0M
4.
Plant homeodomain finger protein 2 as a novel IKAROS target in acute lymphoblastic leukemia
Zheng Ge, Yan Gu, Qi Han, Justin Sloane, Qinyu Ge, Goufeng Gao, Jinlong Ma, Huihui Song, Jiaojiao Hu, Baoan Chen, Sinisa Dovat, Chunhua Song
Epigenomics. 2018 Jan; 10(1): 59–69. Published online 2017 Oct 10. doi: 10.2217/epi-2017-0092
PMCID:
PMC5992565
AbstractArticlePDF–1.0M
5.
HIF-1α-mediated augmentation of miRNA-18b-5p facilitates proliferation and metastasis in osteosarcoma through attenuation PHF2
Peng Luo, Yan-dong Zhang, Feng He, Chang-jun Tong, Kai Liu, He Liu, Shi-zhuang Zhu, Jian-zhou Luo, Bing Yuan
Sci Rep. 2022; 12: 10398. Published online 2022 Jun 21. doi: 10.1038/s41598-022-13660-w
PMCID:
PMC9213540
AbstractArticlePDF–6.6M
6.
PHD Finger Protein 2 (PHF2) Represses Ribosomal RNA Gene Transcription by Antagonizing PHF Finger Protein 8 (PHF8) and Recruiting Methyltransferase SUV39H1
Guang Shi, Meng Wu, Lan Fang, Fang Yu, Shimeng Cheng, Jiwen Li, James X. Du, Jiemin Wong
J Biol Chem. 2014 Oct 24; 289(43): 29691–29700. Published online 2014 Sep 9. doi: 10.1074/jbc.M114.571653
PMCID:
PMC4207983
AbstractArticlePDF–1.5M
7.
Recognition of Histone H3K4 Trimethylation by the Plant Homeodomain of PHF2 Modulates Histone Demethylation
Hong Wen, Jingzhi Li, Tanjing Song, Ming Lu, Pu-Yeh Kan, Min Gyu Lee, Bingdong Sha, Xiaobing Shi
J Biol Chem. 2010 Mar 26; 285(13): 9322–9326. Published online 2010 Feb 2. doi: 10.1074/jbc.C109.097667
PMCID:
PMC2843180
AbstractArticlePDF–1.3M
8.
Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders
Chris Eijsbouts, Tenghao Zheng, Nicholas A. Kennedy, Ferdinando Bonfiglio, Carl A. Anderson, Loukas Moutsianas, Joanne Holliday, Jingchunzi Shi, Suyash Shringarpure, 23andMe Research Team, Alexandru-Ioan Voda, The Bellygenes Initiative, Gianrico Farrugia, Andre Franke, Matthias Hübenthal, Gonçalo Abecasis, Matthew Zawistowski, Anne Heidi Skogholt, Eivind Ness-Jensen, Kristian Hveem, Tõnu Esko, Maris Teder-Laving, Alexandra Zhernakova, Michael Camilleri, Guy Boeckxstaens, Peter J. Whorwell, Robin Spiller, Gil McVean, Mauro D’Amato, Luke Jostins, Miles Parkes
Nat Genet. 2021; 53(11): 1543–1552. Published online 2021 Nov 5. doi: 10.1038/s41588-021-00950-8
PMCID:
PMC8571093
AbstractArticlePDF–7.4M
9.
Alterations in candidate genes PHF2, FANCC, PTCH1 and XPA at chromosomal 9q22.3 region: Pathological significance in early- and late-onset breast carcinoma
Satyabrata Sinha, Ratnesh K Singh, Neyaz Alam, Anup Roy, Susanta Roychoudhury, Chinmay Kumar Panda
Mol Cancer. 2008; 7: 84. Published online 2008 Nov 6. doi: 10.1186/1476-4598-7-84
PMCID:
PMC2633285
AbstractArticlePDF–1.6M
10.
HCF-1 regulates de novo lipogenesis through a nutrient sensitive complex with ChREBP
Elizabeth A. Lane, Dong Wook Choi, Luisa Garcia-Haro, Zebulon G. Levine, Meghan Tedoldi, Suzanne Walker, Nika N. Danial
Mol Cell. Author manuscript; available in PMC 2020 Jul 25.
Published in final edited form as: Mol Cell. 2019 Jul 25; 75(2): 357–371.e7. Published online 2019 Jun 18. doi: 10.1016/j.molcel.2019.05.019
PMCID:
PMC6744259
AbstractArticlePDF–2.9M
11.
De novo genic mutations among a Chinese autism spectrum disorder cohort
Tianyun Wang, Hui Guo, Bo Xiong, Holly A.F. Stessman, Huidan Wu, Bradley P. Coe, Tychele N. Turner, Yanling Liu, Wenjing Zhao, Kendra Hoekzema, Laura Vives, Lu Xia, Meina Tang, Jianjun Ou, Biyuan Chen, Yidong Shen, Guanglei Xun, Min Long, Janice Lin, Zev N. Kronenberg, Yu Peng, Ting Bai, Honghui Li, Xiaoyan Ke, Zhengmao Hu, Jingping Zhao, Xiaobing Zou, Kun Xia, Evan E. Eichler
Nat Commun. 2016; 7: 13316. Published online 2016 Nov 8. doi: 10.1038/ncomms13316
PMCID:
PMC5105161
AbstractArticlePDF–584K
12.
Structural basis for human PHF2 Jumonji domain interaction with metal ions
John R. Horton, Anup K. Upadhyay, Hideharu Hashimoto, Xing Zhang, Xiaodong Cheng
J Mol Biol. Author manuscript; available in PMC 2012 Feb 11.
Published in final edited form as: J Mol Biol. 2011 Feb 11; 406(1): 1–8. Published online 2010 Dec 15. doi: 10.1016/j.jmb.2010.12.013
PMCID:
PMC3030633
AbstractArticlePDF–1.3M
13.
A phospho/methyl switch at histone H3 regulates TFIID association with mitotic chromosomes
Radhika A Varier, Nikolay S Outchkourov, Petra de Graaf, Frederik M A van Schaik, Henk Jan L Ensing, Fangwei Wang, Jonathan M G Higgins, Geert J P L Kops, HTh Marc Timmers
EMBO J. 2010 Dec 1; 29(23): 3967–3978. Published online 2010 Oct 15. doi: 10.1038/emboj.2010.261
PMCID:
PMC3020634
AbstractArticlePDF–1.1M
14.
Identification and Characterization of Nardilysin as a Novel Dimethyl H3K4-binding Protein Involved in Transcriptional Regulation
Jing Li, Mingyue Chu, Shanshan Wang, Doug Chan, Shankang Qi, Meng Wu, Zhongliang Zhou, Jiwen Li, Eiichiro Nishi, Jun Qin, Jiemin Wong
J Biol Chem. 2012 Mar 23; 287(13): 10089–10098. Published online 2012 Jan 30. doi: 10.1074/jbc.M111.313965
PMCID:
PMC3323043
AbstractArticlePDF–1.6M
15.
The contribution of de novo coding mutations to autism spectrum disorder
Ivan Iossifov, Brian J. O’Roak, Stephan J. Sanders, Michael Ronemus, Niklas Krumm, Dan Levy, Holly A. Stessman, Kali Witherspoon, Laura Vives, Karynne E. Patterson, Joshua D. Smith, Bryan Paeper, Deborah A. Nickerson, Jeanselle Dea, Shan Dong, Luis E. Gonzalez, Jefferey D. Mandell, Shrikant M. Mane, Michael T. Murtha, Catherine A. Sullivan, Michael F. Walker, Zainulabedin Waqar, Liping Wei, A. Jeremy Willsey, Boris Yamrom, Yoon-ha Lee, Ewa Grabowska, Ertugrul Dalkic, Zihua Wang, Steven Marks, Peter Andrews, Anthony Leotta, Jude Kendall, Inessa Hakker, Julie Rosenbaum, Beicong Ma, Linda Rodgers, Jennifer Troge, Giuseppe Narzisi, Seungtai Yoon, Michael C. Schatz, Kenny Ye, W. Richard McCombie, Jay Shendure, Evan E. Eichler, Matthew W. State, Michael Wigler
Nature. Author manuscript; available in PMC 2015 May 13.
Published in final edited form as: Nature. 2014 Nov 13; 515(7526): 216–221. Published online 2014 Oct 29. doi: 10.1038/nature13908
PMCID:
PMC4313871
AbstractArticlePDF–377K
16.
CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism
Andrea Piunti, Edwin R. Smith, Marc A. J. Morgan, Michal Ugarenko, Natalia Khaltyan, Kathryn A. Helmin, Caila A. Ryan, David C. Murray, Ryan A. Rickels, Bahar D. Yilmaz, Emily J. Rendleman, Jeffrey N. Savas, Benjamin D. Singer, Serdar E. Bulun, Ali Shilatifard
Sci Adv. 2019 Jul; 5(7): eaax2887. Published online 2019 Jul 3. doi: 10.1126/sciadv.aax2887
PMCID:
PMC6609211
AbstractArticlePDF–1.1M
17.
Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM
Alan S. L. Wong, Gigi C. G. Choi, Cheryl H. Cui, Gabriela Pregernig, Pamela Milani, Miriam Adam, Samuel D. Perli, Samuel W. Kazer, Aleth Gaillard, Mario Hermann, Alex K. Shalek, Ernest Fraenkel, Timothy K. Lu
Proc Natl Acad Sci U S A. 2016 Mar 1; 113(9): 2544–2549. Published online 2016 Feb 10. doi: 10.1073/pnas.1517883113
PMCID:
PMC4780610
AbstractArticlePDF–918K
18.
The Protein Composition of Mitotic Chromosomes Determined Using Multiclassifier Combinatorial Proteomics
Shinya Ohta, Jimi-Carlo Bukowski-Wills, Luis Sanchez-Pulido, Flavia de Lima Alves, Laura Wood, Zhuo A. Chen, Melpi Platani, Lutz Fischer, Damien F. Hudson, Chris P. Ponting, Tatsuo Fukagawa, William C. Earnshaw, Juri Rappsilber
Cell. 2010 Sep 3; 142(5): 810–821. doi: 10.1016/j.cell.2010.07.047
PMCID:
PMC2982257
AbstractArticle
19.
ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation
Yana van der Weegen, Klaas de Lint, Diana van den Heuvel, Yuka Nakazawa, Tycho E.T. Mevissen, Janne J.M. van Schie, Marta San Martin Alonso, Daphne E.C. Boer, Román González-Prieto, Ishwarya V. Narayanan, Noud H.M. Klaassen, Annelotte P. Wondergem, Khashayar Roohollahi, Josephine C. Dorsman, Yuichiro Hara, Alfred C.O. Vertegaal, Job de Lange, Johannes C. Walter, Sylvie M. Noordermeer, Mats Ljungman, Tomoo Ogi, Rob M.F. Wolthuis, Martijn S. Luijsterburg
Nat Cell Biol. Author manuscript; available in PMC 2022 Jun 9.
Published in final edited form as: Nat Cell Biol. 2021 Jun; 23(6): 595–607. Published online 2021 Jun 9. doi: 10.1038/s41556-021-00688-9
PMCID:
PMC8890769
AbstractArticlePDF–7.4M
20.
Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage
Sanna Abbasi, Laila Bayat, Caroline Schild-Poulter
Int J Mol Sci. 2023 Apr; 24(8): 7041. Published online 2023 Apr 11. doi: 10.3390/ijms24087041
PMCID:
PMC10138931
AbstractArticlePDF–4.0M

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