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Select item 40322951.

The PDZ Domain of the Guanine Nucleotide Exchange Factor PDZGEF Directs Binding to Phosphatidic Acid during Brush Border Formation

Sarah V. Consonni, Patricia M. Brouwer, Eleonora S. van Slobbe, Johannes L. Bos

PLoS One. 2014; 9(5): e98253. Published online 2014 May 23. doi: 10.1371/journal.pone.0098253

PMCID:: PMC4032295

Abstract Article PDF–2.3M

Select item 29545872.

BAG3 directly associates with guanine nucleotide exchange factor of Rap1, PDZGEF2, and regulates cell adhesion

Masahiro Iwasaki, Ryoichi Tanaka, Akinori Hishiya, Sachiko Homma, John C. Reed, Shinichi Takayama

Biochem Biophys Res Commun. Author manuscript; available in PMC 2011 Sep 24.

Published in final edited form as: Biochem Biophys Res Commun. 2010 Sep 24; 400(3): 413–418. Published online 2010 Aug 26. doi: 10.1016/j.bbrc.2010.08.092

PMCID:: PMC2954587

Abstract Article PDF–252K

Select item 27469133.

Interaction between Interleukin 3 and Dystrobrevin-Binding Protein 1 in Schizophrenia

Todd L Edwards, Xu Wang, Qi Chen, Brandon Wormly, Brien Riley, F. Anthony O’Neill, Dermot Walsh, Marylyn D. Ritchie, Kenneth S. Kendler, Xiangning Chen

Schizophr Res. Author manuscript; available in PMC 2009 Dec 1.

Published in final edited form as: Schizophr Res. 2008 Dec; 106(2-3): 208–217. Published online 2008 Sep 18. doi: 10.1016/j.schres.2008.07.022

PMCID:: PMC2746913

Abstract Article PDF–886K

Select item 26639254.

Junctional Adhesion Molecule A Interacts with Afadin and PDZ-GEF2 to Activate Rap1A, Regulate β1 Integrin Levels, and Enhance Cell Migration

Eric A. Severson, Winston Y. Lee, Christopher T. Capaldo, Asma Nusrat, Charles A. Parkos

Mol Biol Cell. 2009 Apr 1; 20(7): 1916–1925. doi: 10.1091/mbc.E08-10-1014

PMCID:: PMC2663925

Abstract Article PDF–631K

Select item 37719475.

JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and regulate epithelial barrier function

Ana C. Monteiro, Ronen Sumagin, Carl R. Rankin, Giovanna Leoni, Michael J. Mina, Dirk M. Reiter, Thilo Stehle, Terence S. Dermody, Stacy A. Schaefer, Randy A. Hall, Asma Nusrat, Charles A. Parkos

Mol Biol Cell. 2013 Sep 15; 24(18): 2849–2860. doi: 10.1091/mbc.E13-06-0298

PMCID:: PMC3771947

Abstract Article PDF–1.6M

Select item 60477366.

Deubiquitinating Enzyme USP9X Suppresses Tumor Growth via LATS kinase and Core Components of the Hippo pathway

Aleksandra Toloczko, Fusheng Guo, Hiu-Fung Yuen, Qing Wen, Stephen A. Wood, Yan Shan Ong, Pei Yi Chan, Asfa Alli Shaik, Jayantha Gunaratne, Mark J. Dunne, Wanjin Hong, Siew Wee Chan

Cancer Res. Author manuscript; available in PMC 2018 Jul 16.

Published in final edited form as: Cancer Res. 2017 Sep 15; 77(18): 4921–4933. Published online 2017 Jul 18. doi: 10.1158/0008-5472.CAN-16-3413

PMCID:: PMC6047736

Abstract Article PDF–2.3M

Select item 68841407.

USP9X Deubiquitylates DVL2 to Regulate WNT Pathway Specification

Casey P. Nielsen, Kristin K. Jernigan, Nicole L. Diggins, Donna J. Webb, Jason A. MacGurn

Cell Rep. Author manuscript; available in PMC 2019 Nov 29.

Published in final edited form as: Cell Rep. 2019 Jul 23; 28(4): 1074–1089.e5. doi: 10.1016/j.celrep.2019.06.083

PMCID:: PMC6884140

Abstract Article PDF–2.6M

Select item 67941588.

LZTR1 is a regulator of RAS ubiquitination and signaling

Johannes W. Bigenzahn, Giovanna M. Collu, Felix Kartnig, Melanie Pieraks, Gregory I. Vladimer, Leonhard X. Heinz, Vitaly Sedlyarov, Fiorella Schischlik, Astrid Fauster, Manuele Rebsamen, Katja Parapatics, Vincent A. Blomen, André C. Müller, Georg E. Winter, Robert Kralovics, Thijn R. Brummelkamp, Marek Mlodzik, Giulio Superti-Furga

Science. Author manuscript; available in PMC 2019 Oct 15.

Published in final edited form as: Science. 2018 Dec 7; 362(6419): 1171–1177. Published online 2018 Nov 15. doi: 10.1126/science.aap8210

PMCID:: PMC6794158

Abstract Article PDF–1.9M

Select item 11902559.

WW Domains Provide a Platform for the Assembly of Multiprotein Networks

Robert J. Ingham, Karen Colwill, Caley Howard, Sabine Dettwiler, Caesar S. H. Lim, Joanna Yu, Kadija Hersi, Judith Raaijmakers, Gerald Gish, Geraldine Mbamalu, Lorne Taylor, Benny Yeung, Galina Vassilovski, Manish Amin, Fu Chen, Liudmila Matskova, Gösta Winberg, Ingemar Ernberg, Rune Linding, Paul O'Donnell, Andrei Starostine, Walter Keller, Pavel Metalnikov, Chris Stark, Tony Pawson

Mol Cell Biol. 2005 Aug; 25(16): 7092–7106. doi: 10.1128/MCB.25.16.7092-7106.2005

PMCID:: PMC1190255

Abstract Article PDF–1.1M

Select item 646186410.

LncRNAs-directed PTEN enzymatic switch governs epithelial–mesenchymal transition

Qingsong Hu, Chunlai Li, Shouyu Wang, Yajuan Li, Bo Wen, Yanyan Zhang, Ke Liang, Jun Yao, Youqiong Ye, Heidi Hsiao, Tina K. Nguyen, Peter K. Park, Sergey D. Egranov, David H. Hawke, Jeffrey R. Marks, Leng Han, Mien-Chie Hung, Bing Zhang, Chunru Lin, Liuqing Yang

Cell Res. 2019 Apr; 29(4): 286–304. Published online 2019 Jan 10. doi: 10.1038/s41422-018-0134-3

PMCID:: PMC6461864

Abstract Article PDF–11M

Select item 999012011.

Interactomes of Glycogen Synthase Kinase-3 Isoforms

Kevin W. Cormier, Brett Larsen, Anne-Claude Gingras, James R. Woodgett

J Proteome Res. 2023 Mar 3; 22(3): 977–989. Published online 2023 Feb 13. doi: 10.1021/acs.jproteome.2c00825

PMCID:: PMC9990120

Abstract Article PDF–3.7M

Select item 274057212.

A Genome-wide Short Hairpin RNA Screening of Jurkat T-cells for Human Proteins Contributing to Productive HIV-1 Replication

Man Lung Yeung, Laurent Houzet, Venkat S. R. K. Yedavalli, Kuan-Teh Jeang

J Biol Chem. 2009 Jul 17; 284(29): 19463–19473. Published online 2009 May 20. doi: 10.1074/jbc.M109.010033

PMCID:: PMC2740572

Abstract Article PDF–2.5M

Select item 619728713.

Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II

Yujing Li, Yunhua Liu, Hanchen Xu, Guanglong Jiang, Kevin Van der Jeught, Yuanzhang Fang, Zhuolong Zhou, Lu Zhang, Michael Frieden, Lifei Wang, Zhenhua Luo, Milan Radovich, Bryan P. Schneider, Yibin Deng, Yunlong Liu, Kun Huang, Bin He, Jin Wang, Xiaoming He, Xinna Zhang, Guang Ji, Xiongbin Lu

Nat Commun. 2018; 9: 4394. Published online 2018 Oct 22. doi: 10.1038/s41467-018-06811-z

PMCID:: PMC6197287

Abstract Article PDF–1.9M

Select item 761053514.

PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase

Bikash Adhikari, Jelena Bozilovic, Mathias Diebold, Jessica Denise Schwarz, Julia Hofstetter, Martin Schröder, Marek Wanior, Ashwin Narain, Markus Vogt, Nevenka Dudvarski Stankovic, Apoorva Baluapuri, Lars Schönemann, Lorenz Eing, Pranjali Bhandare, Bernhard Kuster, Andreas Schlosser, Stephanie Heinzlmeir, Christoph Sotriffer, Stefan Knapp, Elmar Wolf

Nat Chem Biol. Author manuscript; available in PMC 2021 Apr 6.

Published in final edited form as: Nat Chem Biol. 2020 Nov 1; 16(11): 1179–1188. Published online 2020 Sep 28. doi: 10.1038/s41589-020-00652-y

PMCID:: PMC7610535

Abstract Article PDF–5.1M

Select item 808827415.

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch

Agnieszka T. Kawashima, Cassandra Wong, Gema Lordén, Charles C. King, Pablo Lara-Gonzalez, Arshad Desai, Anne-Claude Gingras, Alexandra C. Newton

Mol Cell Biol. 2021 Mar; 41(3): e00333-20. Prepublished online 2021 Jan 4. Published online 2021 Feb 23. doi: 10.1128/MCB.00333-20

PMCID:: PMC8088274

Abstract Article PDF–3.1M

Select item 401998116.

Interaction proteome of human Hippo signaling: modular control of the co‐activator YAP1

Simon Hauri, Alexander Wepf, Audrey van Drogen, Markku Varjosalo, Nic Tapon, Ruedi Aebersold, Matthias Gstaiger

Mol Syst Biol. 2013; 9: 713. Published online 2013 Dec 20. doi: 10.1002/msb.201304750

PMCID:: PMC4019981

Abstract Article PDF–915K

Select item 1094246717.

Mitochondrial Raf1 Regulates Glutamine Catabolism

Ronald L. Shanderson, Ian D. Ferguson, Zurab Siprashvili, Luca Ducoli, Albert M. Li, Weili Miao, Suhas Srinivasan, Mary Grace Velasco, Yang Li, Jiangbin Ye, Paul A. Khavari

Version 1. bioRxiv. Preprint. 2024 Mar 9. doi: 10.1101/2024.03.08.581297

PMCID:: PMC10942467

Abstract Article PDF–6.5M

Select item 831454718.

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation

Ruona Shi, Xue Shi, Dajiang Qin, Shibing Tang, Michiel Vermeulen, Xiaofei Zhang

Cell Biosci. 2021; 11: 146. Published online 2021 Jul 27. doi: 10.1186/s13578-021-00659-5

PMCID:: PMC8314547

Abstract Article PDF–3.7M

Select item 876907219.

Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584

PMCID:: PMC8769072

Abstract Article PDF–2.9M

Select item 876331720.

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation

Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley

Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h

PMCID:: PMC8763317

Abstract Article

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PMC Links for Gene (Select 51735) (40)
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Homo sapiens Rap guanine nucleotide exchange factor 6 (RAPGEF6), transcript vari...
Homo sapiens Rap guanine nucleotide exchange factor 6 (RAPGEF6), transcript variant 6, mRNA
gi|1677538655|ref|NM_001164390.2|

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