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Select item 81210961.

PHF20 inhibition promotes apoptosis and cisplatin chemosensitivity via the OCT4-p-STAT3-MCL1 signaling pathway in hypopharyngeal squamous cell carcinoma

Xiuxiu Liu, Zhancheng Zhang, Shifeng Kan, Zhenghua Lv, Shengli Zhou, Xianfang Liu, Peihang Jing, Wei Xu

Int J Oncol. 2021 Jul; 59(1): 38. Published online 2021 May 7. doi: 10.3892/ijo.2021.5218

PMCID:: PMC8121096

Abstract Article PDF–2.0M

Select item 23660632.

Increased Seroreactivity to Glioma-Expressed Antigen 2 in Brain Tumor Patients under Radiation

Sabrina M. Heisel, Ralf Ketter, Andreas Keller, Veronika Klein, Christian P. Pallasch, Hans-Peter Lenhof, Eckart Meese

PLoS One. 2008; 3(5): e2164. Published online 2008 May 14. doi: 10.1371/journal.pone.0002164

PMCID:: PMC2366063

Abstract Article PDF–219K

Select item 19061873.

Glioma-expressed antigen 2 (GLEA2): a novel protein that can elicit immune responses in glioblastoma patients and some controls

U Fischer, A-K Struss, D Hemmer, C P Pallasch, W-I Steudel, E Meese

Clin Exp Immunol. 2001 Nov; 126(2): 206–213. doi: 10.1046/j.1365-2249.2001.01635.x

PMCID:: PMC1906187

Abstract Article PDF–1.7M

Select item 93863234.

N6‐methyladenosine demethylase ALKBH5 suppresses colorectal cancer progression potentially by decreasing PHF20 mRNA methylation

Zhen Zhang, Ling Wang, Long Zhao, Quan Wang, Changjiang Yang, Mengmeng Zhang, Bo Wang, Kewei Jiang, Yingjiang Ye, Shan Wang, Zhanlong Shen

Clin Transl Med. 2022 Aug; 12(8): e940. Published online 2022 Aug 17. doi: 10.1002/ctm2.940

PMCID:: PMC9386323

Abstract Article PDF–6.1M

Select item 51257285.

PHF20 Readers Link Methylation of Histone H3K4 and p53 with H4K16 Acetylation

Brianna J. Klein, Xiaoyan Wang, Gaofeng Cui, Chao Yuan, Maria Victoria Botuyan, Kevin Lin, Yue Lu, Xiaolu Wang, Yue Zhao, Christiane J. Bruns, Georges Mer, Xiaobing Shi, Tatiana G. Kutateladze

Cell Rep. Author manuscript; available in PMC 2016 Nov 28.

Published in final edited form as: Cell Rep. 2016 Oct 18; 17(4): 1158–1170. doi: 10.1016/j.celrep.2016.09.056

PMCID:: PMC5125728

Abstract Article PDF–2.1M

Select item 46803496.

Expression of PHF20 protein contributes to good prognosis of NSCLC and is associated with Bax expression

Na Tang, Lin Ma, Xu-Yong Lin, Yong Zhang, Da-Lei Yang, En-Hua Wang, Xue-Shan Qiu

Int J Clin Exp Pathol. 2015; 8(10): 12198–12206. Published online 2015 Oct 1.

PMCID:: PMC4680349

Abstract Article PDF–1.5M

Select item 39428847.

PHF20 regulates NF-κB signalling by disrupting recruitment of PP2A to p65

Tiejun Zhang, Kyeong Ah Park, Yuwen Li, Hee Sun Byun, Juhee Jeon, Yoonjung Lee, Jang Hee Hong, Jin Man Kim, Song-Mei Huang, Seung-Won Choi, Sun-Hwan Kim, Kyung-Cheol Sohn, Hyunju Ro, Ji Hoon Lee, Tao Lu, George R. Stark, Han-Ming Shen, Zheng-gang Liu, Jongsun Park, Gang Min Hur

Nat Commun. Author manuscript; available in PMC 2014 Mar 5.

Published in final edited form as: Nat Commun. 2013; 4: 2062. doi: 10.1038/ncomms3062

PMCID:: PMC3942884

Abstract Article PDF–5.2M

Select item 34545138.

PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53

Gaofeng Cui, Sungman Park, Aimee I Badeaux, Donghwa Kim, Joseph Lee, James R Thompson, Fei Yan, Satoshi Kaneko, Zengqiang Yuan, Maria Victoria Botuyan, Mark T Bedford, Jin Q Cheng, Georges Mer

Nat Struct Mol Biol. Author manuscript; available in PMC 2013 Mar 1.

Published in final edited form as: Nat Struct Mol Biol. 2012 Sep; 19(9): 916–924. Published online 2012 Aug 5. doi: 10.1038/nsmb.2353

PMCID:: PMC3454513

Abstract Article PDF–3.2M

Select item 59511219.

PHF20 collaborates with PARP1 to promote stemness and aggressiveness of neuroblastoma cells through activation of SOX2 and OCT4

Wenyong Long, Wei Zhao, Bo Ning, Jing Huang, Junjun Chu, Linfeng Li, Qianquan Ma, Changsheng Xing, Helen Y Wang, Qing Liu, Rong-Fu Wang

J Mol Cell Biol. 2018 Apr; 10(2): 147–160. Published online 2018 Mar 12. doi: 10.1093/jmcb/mjy007

PMCID:: PMC5951121

Abstract Article PDF–1.6M

Select item 479292610.

G9a-mediated methylation of ERα links the PHF20/MOF histone acetyltransferase complex to hormonal gene expression

Xi Zhang, Danni Peng, Yuanxin Xi, Chao Yuan, Cari A. Sagum, Brianna J. Klein, Kaori Tanaka, Hong Wen, Tatiana G. Kutateladze, Wei Li, Mark T. Bedford, Xiaobing Shi

Nat Commun. 2016; 7: 10810. Published online 2016 Mar 10. doi: 10.1038/ncomms10810

PMCID:: PMC4792926

Abstract Article PDF–1.9M

Select item 382813311.

Crosstalk between NSL Histone Acetyltransferase and MLL/SET Complexes: NSL Complex Functions in Promoting Histone H3K4 Di-Methylation Activity by MLL/SET Complexes

Xiaoming Zhao, Jiaming Su, Fei Wang, Da Liu, Jian Ding, Yang Yang, Joan W. Conaway, Ronald C. Conaway, Lingling Cao, Donglu Wu, Min Wu, Yong Cai, Jingji Jin

PLoS Genet. 2013 Nov; 9(11): e1003940. Published online 2013 Nov 14. doi: 10.1371/journal.pgen.1003940

PMCID:: PMC3828133

Abstract Article PDF–1.6M

Select item 758520312.

The histone and non-histone methyllysine reader activities of the UHRF1 tandem Tudor domain are dispensable for the propagation of aberrant DNA methylation patterning in cancer cells

Robert M. Vaughan, Ariana Kupai, Caroline A. Foley, Cari A. Sagum, Bailey M. Tibben, Hope E. Eden, Rochelle L. Tiedemann, Christine A. Berryhill, Varun Patel, Kevin M. Shaw, Krzysztof Krajewski, Brian D. Strahl, Mark T. Bedford, Stephen V. Frye, Bradley M. Dickson, Scott B. Rothbart

Epigenetics Chromatin. 2020; 13: 44. Published online 2020 Oct 23. doi: 10.1186/s13072-020-00366-4

PMCID:: PMC7585203

Abstract Article PDF–5.8M

Select item 289756213.

MOF and Histone H4 Acetylation at Lysine 16 Are Critical for DNA Damage Response and Double-Strand Break Repair

Girdhar G. Sharma, Sairei So, Arun Gupta, Rakesh Kumar, Christelle Cayrou, Nikita Avvakumov, Utpal Bhadra, Raj K. Pandita, Matthew H. Porteus, David J. Chen, Jacques Cote, Tej K. Pandita

Mol Cell Biol. 2010 Jul; 30(14): 3582–3595. Published online 2010 May 17. doi: 10.1128/MCB.01476-09

PMCID:: PMC2897562

Abstract Article PDF–2.0M

Select item 405988914.

MOF-associated complexes ensure stem cell identity and Xist repression

Tomasz Chelmicki, Friederike Dündar, Matthew James Turley, Tasneem Khanam, Tugce Aktas, Fidel Ramírez, Anne-Valerie Gendrel, Patrick Rudolf Wright, Pavankumar Videm, Rolf Backofen, Edith Heard, Thomas Manke, Asifa Akhtar

eLife. 2014; 3: e02024. Published online 2014 May 19. doi: 10.7554/eLife.02024

PMCID:: PMC4059889

Abstract Article PDF–9.7M

Select item 283603015.

Subunit Composition and Substrate Specificity of a MOF-containing Histone Acetyltransferase Distinct from the Male-specific Lethal (MSL) Complex

Yong Cai, Jingji Jin, Selene K. Swanson, Michael D. Cole, Seung Hyuk Choi, Laurence Florens, Michael P. Washburn, Joan W. Conaway, Ronald C. Conaway

J Biol Chem. 2010 Feb 12; 285(7): 4268–4272. Published online 2009 Dec 14. doi: 10.1074/jbc.C109.087981

PMCID:: PMC2836030

Abstract Article PDF–1.2M

Select item 145690216.

Tudor, MBT and chromo domains gauge the degree of lysine methylation

Jeesun Kim, Jeremy Daniel, Alexsandra Espejo, Aimee Lake, Murli Krishna, Li Xia, Yi Zhang, Mark T Bedford

EMBO Rep. 2006 Apr; 7(4): 397–403. Published online 2006 Jan 13. doi: 10.1038/sj.embor.7400625

PMCID:: PMC1456902

Abstract Article PDF–199K

Select item 404112317.

Genome-wide meta-analysis identifies new susceptibility loci for migraine

Verneri Anttila, Bendik S. Winsvold, Padhraig Gormley, Tobias Kurth, Francesco Bettella, George McMahon, Mikko Kallela, Rainer Malik, Boukje de Vries, Gisela Terwindt, Sarah E. Medland, Unda Todt, Wendy L. McArdle, Lydia Quaye, Markku Koiranen, M. Arfan Ikram, Terho Lehtimäki, Anine H. Stam, Lannie Ligthart, Juho Wedenoja, Ian Dunham, Benjamin M. Neale, Priit Palta, Eija Hamalainen, Markus Schürks, Lynda M Rose, Julie E. Buring, Paul M. Ridker, Stacy Steinberg, Hreinn Stefansson, Finnbogi Jakobsson, Debbie A. Lawlor, David M. Evans, Susan M. Ring, Markus Färkkilä, Ville Artto, Mari A Kaunisto, Tobias Freilinger, Jean Schoenen, Rune R. Frants, Nadine Pelzer, Claudia M. Weller, Ronald Zielman, Andrew C. Heath, Pamela A.F. Madden, Grant W. Montgomery, Nicholas G. Martin, Guntram Borck, Hartmut Göbel, Axel Heinze, Katja Heinze-Kuhn, Frances M.K. Williams, Anna-Liisa Hartikainen, Anneli Pouta, Joyce van den Ende, Andre G. Uitterlinden, Albert Hofman, Najaf Amin, Jouke-Jan Hottenga, Jacqueline M. Vink, Kauko Heikkilä, Michael Alexander, Bertram Muller-Myhsok, Stefan Schreiber, Thomas Meitinger, Heinz Erich Wichmann, Arpo Aromaa, Johan G. Eriksson, Bryan Traynor, Daniah Trabzuni, North American Brain Expression Consortium, UK Brain Expression Consortium, Elizabeth Rossin, Kasper Lage, Suzanne B.R. Jacobs, J. Raphael Gibbs, Ewan Birney, Jaakko Kaprio, Brenda W. Penninx, Dorret I. Boomsma, Cornelia van Duijn, Olli Raitakari, Marjo-Riitta Jarvelin, John-Anker Zwart, Lynn Cherkas, David P. Strachan, Christian Kubisch, Michel D. Ferrari, Arn M.J.M. van den Maagdenberg, Martin Dichgans, Maija Wessman, George Davey Smith, Kari Stefansson, Mark J. Daly, Dale R. Nyholt, Daniel Chasman, Aarno Palotie

Nat Genet. Author manuscript; available in PMC 2014 Jun 2.

Published in final edited form as: Nat Genet. 2013 Aug; 45(8): 912–917. Published online 2013 Jun 23. doi: 10.1038/ng.2676

PMCID:: PMC4041123

Article PDF–571K

Select item 642009718.

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination in sister chromatids

Kyosuke Nakamura, Giulia Saredi, Jordan R. Becker, Benjamin M. Foster, Nhuong V. Nguyen, Tracey Beyer, Laura C. Cesa, Peter A. Faull, Saulius Lukauskas, Thomas Frimurer, J. Ross Chapman, Till Bartke, Anja Groth

Nat Cell Biol. Author manuscript; available in PMC 2019 Aug 25.

Published in final edited form as: Nat Cell Biol. 2019 Mar; 21(3): 311–318. Published online 2019 Feb 25. doi: 10.1038/s41556-019-0282-9

PMCID:: PMC6420097

Article PDF–1.7M

Select item 298946119.

Systematic Characterization of Human Protein Complexes Identifies Chromosome Segregation Proteins

James R.A. Hutchins, Yusuke Toyoda, Björn Hegemann, Ina Poser, Jean-Karim Hériché, Martina M. Sykora, Martina Augsburg, Otto Hudecz, Bettina A. Buschhorn, Jutta Bulkescher, Christian Conrad, David Comartin, Alexander Schleiffer, Mihail Sarov, Andrei Pozniakovsky, Mikolaj Michal Slabicki, Siegfried Schloissnig, Ines Steinmacher, Marit Leuschner, Andrea Ssykor, Steffen Lawo, Laurence Pelletier, Holger Stark, Kim Nasmyth, Jan Ellenberg, Richard Durbin, Frank Buchholz, Karl Mechtler, Anthony A. Hyman, Jan-Michael Peters

Science. Author manuscript; available in PMC 2010 Nov 22.

Published in final edited form as: Science. 2010 Apr 30; 328(5978): 593–599. Published online 2010 Apr 1. doi: 10.1126/science.1181348

PMCID:: PMC2989461

Abstract Article PDF–2.2M

Select item 732206720.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

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