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Items: 1 to 20 of 62

1.
HERC5 downregulation in non-small cell lung cancer is associated with altered energy metabolism and metastasis
Svenja Schneegans, Jana Löptien, Angelika Mojzisch, Desirée Loreth, Oliver Kretz, Christoph Raschdorf, Annkathrin Hanssen, Antonia Gocke, Bente Siebels, Karthikeyan Gunasekaran, Yi Ding, Leticia Oliveira-Ferrer, Laura Brylka, Thorsten Schinke, Hartmut Schlüter, Ilkka Paatero, Hannah Voß, Stefan Werner, Klaus Pantel, Harriet Wikman
J Exp Clin Cancer Res. 2024; 43: 110. Published online 2024 Apr 11. doi: 10.1186/s13046-024-03020-z
PMCID:
PMC11008035
AbstractArticlePDF–6.4M
2.
HERC5 and the ISGylation Pathway: Critical Modulators of the Antiviral Immune Response
Nicholas A. Mathieu, Ermela Paparisto, Stephen D. Barr, Donald E. Spratt
Viruses. 2021 Jun; 13(6): 1102. Published online 2021 Jun 9. doi: 10.3390/v13061102
PMCID:
PMC8228270
AbstractArticlePDF–1.0M
3.
Rapid Evolution of HERC6 and Duplication of a Chimeric HERC5/6 Gene in Rodents and Bats Suggest an Overlooked Role of HERCs in Mammalian Immunity
Stéphanie Jacquet, Dominique Pontier, Lucie Etienne
Front Immunol. 2020; 11: 605270. Published online 2020 Dec 18. doi: 10.3389/fimmu.2020.605270
PMCID:
PMC7775381
AbstractArticlePDF–4.2M
4.
Evolution-Guided Structural and Functional Analyses of the HERC Family Reveal an Ancient Marine Origin and Determinants of Antiviral Activity
Ermela Paparisto, Matthew W. Woods, Macon D. Coleman, Seyed A. Moghadasi, Divjyot S. Kochar, Sean K. Tom, Hinissan P. Kohio, Richard M. Gibson, Taryn J. Rohringer, Nina R. Hunt, Eric J. Di Gravio, Jonathan Y. Zhang, Meijuan Tian, Yong Gao, Eric J. Arts, Stephen D. Barr
J Virol. 2018 Jul 1; 92(13): e00528-18. Prepublished online 2018 Apr 18. Published online 2018 Jun 13. doi: 10.1128/JVI.00528-18
PMCID:
PMC6002735
AbstractArticlePDF–3.9M
5.
HERC5 is a prognostic biomarker for post-liver transplant recurrent human hepatocellular carcinoma
Feng Xue, Brandon W. Higgs, Jiaqi Huang, Chris Morehouse, Wei Zhu, Xin Yao, Philip Brohawn, Zhan Xiao, Yinong Sebastian, Zheng Liu, Yun Xia, Dong Shen, Mike Kuziora, Zhengwei Dong, Hulin Han, Yi Gu, Jianren Gu, Qiang Xia, Yihong Yao
J Transl Med. 2015; 13: 379. Published online 2015 Dec 11. doi: 10.1186/s12967-015-0743-2
PMCID:
PMC4676172
AbstractArticlePDF–3.4M
6.
Antiviral activity of ISG15 against classical swine fever virus replication in porcine alveolar macrophages via inhibition of autophagy by ISGylating BECN1
Cheng Li, Yifan Wang, Hongqing Zheng, Wang Dong, Huifang Lv, Jihui Lin, Kangkang Guo, Yanming Zhang
Vet Res. 2020; 51: 22. Published online 2020 Feb 24. doi: 10.1186/s13567-020-00753-5
PMCID:
PMC7038623
AbstractArticlePDF–4.4M
7.
CYP1B1 Activates Wnt/β-Catenin Signaling through Suppression of Herc5-Mediated ISGylation for Protein Degradation on β-Catenin in HeLa Cells
Young-Shin Park, Yeo-Jung Kwon, Young-Jin Chun
Toxicol Res. 2017 Jul; 33(3): 211–218. Published online 2017 Jul 15. doi: 10.5487/TR.2017.33.3.211
PMCID:
PMC5523555
AbstractArticlePDF–1.7M
8.
Inhibition of hepatitis C virus RNA replication by ISG15 does not require its conjugation to protein substrates by the HERC5 E3 ligase
Patricia Domingues, Connor G. G. Bamford, Chris Boutell, John McLauchlan
J Gen Virol. 2015 Nov; 96(Pt 11): 3236–3242. doi: 10.1099/jgv.0.000283
PMCID:
PMC4806579
AbstractArticlePDF–282K
9.
Paternal lifestyle as a potential source of germline mutations transmitted to offspring
Joost O. Linschooten, Nicole Verhofstad, Kristine Gutzkow, Ann-Karin Olsen, Carole Yauk, Yvonne Oligschläger, Gunnar Brunborg, Frederik J. van Schooten, Roger W. L. Godschalk
FASEB J. 2013 Jul; 27(7): 2873–2879. doi: 10.1096/fj.13-227694
PMCID:
PMC3688758
AbstractArticle
10.
ISG15 conjugation system targets the viral NS1 protein in influenza A virus–infected cells
Chen Zhao, Tien-Ying Hsiang, Rei-Lin Kuo, Robert M. Krug
Proc Natl Acad Sci U S A. 2010 Feb 2; 107(5): 2253–2258. Published online 2010 Jan 19. doi: 10.1073/pnas.0909144107
PMCID:
PMC2836655
AbstractArticlePDF–508K
11.
90K Glycoprotein Promotes Degradation of Mutant β-Catenin Lacking the ISGylation or Phosphorylation Sites in the N-terminus
So-Yeon Park, Somy Yoon, Hangun Kim, Kyung Keun Kim
Neoplasia. 2016 Oct; 18(10): 618–625. Published online 2016 Sep 23. doi: 10.1016/j.neo.2016.08.006
PMCID:
PMC5037265
AbstractArticlePDF–987K
12.
Covalent ISG15 conjugation positively regulates the ubiquitin E3 ligase activity of parkin
Eunju Im, Lang Yoo, Minju Hyun, Woo Hyun Shin, Kwang Chul Chung
Open Biol. 2016 Aug; 6(8): 160193. Published online 2016 Aug 17. doi: 10.1098/rsob.160193
PMCID:
PMC5008018
AbstractArticlePDF–1.4M
13.
Oncogene-mediated regulation of p53 ISGylation and functions
Yi-Fu Huang, Dmitry V. Bulavin
Oncotarget. 2014 Jul; 5(14): 5808–5818. Published online 2014 Jul 11. doi: 10.18632/oncotarget.2199
PMCID:
PMC4170631
AbstractArticlePDF–1.4M
14.
Human HERC5 restricts an early stage of HIV-1 assembly by a mechanism correlating with the ISGylation of Gag
Matthew W Woods, Jenna N Kelly, Clayton J Hattlmann, Jessica GK Tong, Li S Xu, Macon D Coleman, Graeme R Quest, James R Smiley, Stephen D Barr
Retrovirology. 2011; 8: 95. Published online 2011 Nov 17. doi: 10.1186/1742-4690-8-95
PMCID:
PMC3228677
AbstractArticlePDF–3.2M
15.
Posttranslational ISGylation of NLRP3 by HERC enzymes facilitates inflammasome activation in models of inflammation
Ying Qin, Xintong Meng, Mengge Wang, Wenbo Liang, Rong Xu, Jingchunyu Chen, Hui Song, Yue Fu, Jingxin Li, Chengjiang Gao, Mutian Jia, Chunyuan Zhao, Wei Zhao
J Clin Invest. 2023 Oct 16; 133(20): e161935. Published online 2023 Oct 16. doi: 10.1172/JCI161935
PMCID:
PMC10575725
AbstractArticlePDF–10M
16.
ISG15 Modulates Type I Interferon Signaling and the Antiviral Response during Hepatitis E Virus Replication
Harini Sooryanarain, Adam J. Rogers, Dianjun Cao, Mary Etna R. Haac, Yogesh A. Karpe, Xiang-Jin Meng
J Virol. 2017 Oct 1; 91(19): e00621-17. Prepublished online 2017 Jul 19. Published online 2017 Sep 12. doi: 10.1128/JVI.00621-17
PMCID:
PMC5599768
AbstractArticlePDF–1.7M
17.
Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 1 Interacts with a Member of the Interferon-Stimulated Gene 15 Pathway
Sarah R. Jacobs, Charles M. Stopford, John A. West, Christopher L. Bennett, Louise Giffin, Blossom Damania
J Virol. 2015 Nov 15; 89(22): 11572–11583. Published online 2015 Sep 9. doi: 10.1128/JVI.01482-15
PMCID:
PMC4645652
AbstractArticlePDF–1.9M
18.
Positive Regulation of Interferon Regulatory Factor 3 Activation by Herc5 via ISG15 Modification
He-Xin Shi, Kai Yang, Xing Liu, Xin-Yi Liu, Bo Wei, Yu-Fei Shan, Lian-Hui Zhu, Chen Wang
Mol Cell Biol. 2010 May; 30(10): 2424–2436. Published online 2010 Mar 22. doi: 10.1128/MCB.01466-09
PMCID:
PMC2863703
AbstractArticlePDF–2.5M
19.
Negative Feedback Regulation of RIG-I-Mediated Antiviral Signaling by Interferon-Induced ISG15 Conjugation
Min-Jung Kim, Sun-Young Hwang, Tadaatsu Imaizumi, Joo-Yeon Yoo
J Virol. 2008 Feb; 82(3): 1474–1483. Published online 2007 Dec 5. doi: 10.1128/JVI.01650-07
PMCID:
PMC2224411
AbstractArticlePDF–894K
20.
Interferon-induced HERC5 is evolving under positive selection and inhibits HIV-1 particle production by a novel mechanism targeting Rev/RRE-dependent RNA nuclear export
Matthew William Woods, Jessica Gayle Tong, Sean Kevin Tom, Peter Anthony Szabo, Peter Craig Cavanagh, Jimmy Dimitrios Dikeakos, SM Mansour Haeryfar, Stephen Dominic Barr
Retrovirology. 2014; 11: 27. Published online 2014 Apr 3. doi: 10.1186/1742-4690-11-27
PMCID:
PMC4021598
AbstractArticlePDF–3.4M

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