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Select item 67950791.

SAR1B GTPase is necessary to protect intestinal cells from disorders of lipid homeostasis, oxidative stress, and inflammation

Alain Sané, Lena Ahmarani, Edgard Delvin, Nikolas Auclair, Schohraya Spahis, Emile Levy

J Lipid Res. 2019 Oct; 60(10): 1755–1764. Published online 2019 Aug 13. doi: 10.1194/jlr.RA119000119

PMCID:: PMC6795079

Abstract Article PDF–1.1M

Select item 39242882.

The Endoplasmic Reticulum Coat Protein II Transport Machinery Coordinates Cellular Lipid Secretion and Cholesterol Biosynthesis

Lee G. D. Fryer, Bethan Jones, Emma J. Duncan, Claire E. Hutchison, Tozen Ozkan, Paul A. Williams, Olivia Alder, Max Nieuwdorp, Anna K. Townley, Arjen R. Mensenkamp, David J. Stephens, Geesje M. Dallinga-Thie, Carol C. Shoulders

J Biol Chem. 2014 Feb 14; 289(7): 4244–4261. Published online 2013 Dec 13. doi: 10.1074/jbc.M113.479980

PMCID:: PMC3924288

Abstract Article PDF–1.4M

Select item 73072103.

Small sequence variations between two mammalian paralogs of the small GTPase SAR1 underlie functional differences in coat protein complex II assembly

David B. Melville, Sean Studer, Randy Schekman

J Biol Chem. 2020 Jun 19; 295(25): 8401–8412. Published online 2020 May 1. doi: 10.1074/jbc.RA120.012964

PMCID:: PMC7307210

Abstract Article PDF–3.9M

Select item 61684164.

Small GTPases SAR1A and SAR1B regulate the trafficking of the cardiac sodium channel Na_v1.5

Zhijie Wang, Gang Yu, Yinan Liu, Shiyong Liu, Meir Aridor, Yuan Huang, Yushuang Hu, Longfei Wang, Sisi Li, Hongbo Xiong, Bo Tang, Xia Li, Chen Cheng, Susmita Chakrabarti, Fan Wang, Qingyu Wu, Sadashiva S. Karnik, Chengqi Xu, Qiuyun Chen, Qing K. Wang

Biochim Biophys Acta Mol Basis Dis. Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2018 Nov; 1864(11): 3672–3684. Published online 2018 Sep 6. doi: 10.1016/j.bbadis.2018.09.003

PMCID:: PMC6168416

Abstract Article PDF–1.9M

Select item 59775215.

Identification and Characterization of Nine Novel Human Small GTPases Showing Variable Expressions in Liver Cancer Tissues

Hua He, Fangyan Dai, Long Yu, Xingyu She, Yong Zhao, Jianmin Jiang, Xiaosong Chen, Shouyuan Zhao

Gene Expr. 2002; 10(5-6): 231–242. Published online 2018 May 31. doi: 10.3727/000000002783992406

PMCID:: PMC5977521

Abstract Article PDF–1.3M

Select item 58530806.

Complex genetic architecture in severe hypobetalipoproteinemia

Linda R. Wang, Adam D. McIntyre, Robert A. Hegele

Lipids Health Dis. 2018; 17: 48. Published online 2018 Mar 14. doi: 10.1186/s12944-018-0680-1

PMCID:: PMC5853080

Abstract Article PDF–674K

Select item 47816437.

Secretory protein trafficking and organelle dynamics in living cells.

J Lippincott-Schwartz, T H Roberts, K Hirschberg

Annu Rev Cell Dev Biol. 2000; 16: 557–589. doi: 10.1146/annurev.cellbio.16.1.557

PMCID:: PMC4781643

Abstract Article

Select item 111718018.

Identification of an FMNL2 Interactome by Quantitative Mass Spectrometry

Sarah Fox, Antoine Gaudreau-LaPierre, Ryan Reshke, Irina Podinic, Derrick J. Gibbings, Laura Trinkle-Mulcahy, John W. Copeland

Int J Mol Sci. 2024 Jun; 25(11): 5686. Published online 2024 May 23. doi: 10.3390/ijms25115686

PMCID:: PMC11171801

Abstract Article PDF–3.1M

Select item 48607749.

A genome-wide IR-induced RAD51 foci RNAi screen identifies CDC73 involved in chromatin remodeling for DNA repair

Patrick Herr, Cecilia Lundin, Bastiaan Evers, Daniel Ebner, Christina Bauerschmidt, Guy Kingham, Timea Palmai-Pallag, Oliver Mortusewicz, Oliver Frings, Erik Sonnhammer, Thomas Helleday

Cell Discov. 2015; 1: 15034. Published online 2015 Dec 1. doi: 10.1038/celldisc.2015.34

PMCID:: PMC4860774

Abstract Article PDF–4.1M

Select item 791045910.

Combinatorial CRISPR screen identifies fitness effects of gene paralogues

Nicola A. Thompson, Marco Ranzani, Louise van der Weyden, Vivek Iyer, Victoria Offord, Alastair Droop, Fiona Behan, Emanuel Gonçalves, Anneliese Speak, Francesco Iorio, James Hewinson, Victoria Harle, Holly Robertson, Elizabeth Anderson, Beiyuan Fu, Fengtang Yang, Guido Zagnoli-Vieira, Phil Chapman, Martin Del Castillo Velasco-Herrera, Mathew J. Garnett, Stephen P. Jackson, David J. Adams

Nat Commun. 2021; 12: 1302. Published online 2021 Feb 26. doi: 10.1038/s41467-021-21478-9

PMCID:: PMC7910459

Abstract Article PDF–3.3M

Select item 913694311.

Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy

Bhaskar Saha, Michelle Salemi, Geneva L. Williams, Seeun Oh, Michael L. Paffett, Brett Phinney, Michael A. Mandell

Cell Rep. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell Rep. 2022 May 10; 39(6): 110797. doi: 10.1016/j.celrep.2022.110797

PMCID:: PMC9136943

Abstract Article PDF–3.2M

Select item 760600812.

BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A

Chun‐guo Mao, Sha‐sha Jiang, Cheng Shen, Tan Long, Hua Jin, Qun‐You Tan, Bo Deng

Thorac Cancer. 2020 Nov; 11(11): 3326–3336. Published online 2020 Oct 1. doi: 10.1111/1759-7714.13676

PMCID:: PMC7606008

Abstract Article PDF–2.5M

Select item 655126613.

FAM105A/OTULINL is a pseudodebuiquitinase of the OTU-class that localizes to the ER membrane

Derek F. Ceccarelli, Sofiia Ivantsiv, Amber Anne Mullin, Etienne Coyaud, Noah Manczyk, Pierre Maisonneuve, Igor Kurinov, Liang Zhao, Chris Go, Anne-Claude Gingras, Brian Raught, Sabine Cordes, Frank Sicheri

Structure. Author manuscript; available in PMC 2020 Jun 4.

Published in final edited form as: Structure. 2019 Jun 4; 27(6): 1000–1012.e6. Published online 2019 May 2. doi: 10.1016/j.str.2019.03.022

PMCID:: PMC6551266

Abstract Article PDF–3.4M

Select item 673723014.

Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant

Ana M. Matos, Francisco R. Pinto, Patrícia Barros, Margarida D. Amaral, Rainer Pepperkok, Paulo Matos

J Biol Chem. 2019 Sep 6; 294(36): 13396–13410. Published online 2019 Jul 19. doi: 10.1074/jbc.RA119.008738

PMCID:: PMC6737230

Abstract Article PDF–2.6M

Select item 903755415.

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy

Bing-Ru Yan, Taoyingnan Li, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Yuhuan Zhou, Peter K. Kim, Brian Raught, John H. Brumell

Autophagy. 2022; 18(4): 829–840. Published online 2021 Aug 25. doi: 10.1080/15548627.2021.1960116

PMCID:: PMC9037554

Abstract Article PDF–4.1M

Select item 1064152416.

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis

Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley

J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295

PMCID:: PMC10641524

Abstract Article PDF–3.8M

Select item 790504017.

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer

Hantao Wang, Junjie Xing, Wei Wang, Guifen Lv, Haiyan He, Yeqing Lu, Mei Sun, Haiyan Chen, Xu Li

Front Cell Dev Biol. 2020; 8: 601502. Published online 2021 Feb 11. doi: 10.3389/fcell.2020.601502

PMCID:: PMC7905040

Abstract Article PDF–3.2M

Select item 943393818.

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB

Fu‐Long Li, Zhengming Wu, Yong‐Qi Gao, Forrest Z Bowling, J Matthew Franklin, Chongze Hu, Raymond T Suhandynata, Michael A Frohman, Michael V Airola, Huilin Zhou, Kun‐Liang Guan

EMBO J. 2022 Sep; 41(17): e110698. Published online 2022 Jul 17. doi: 10.15252/embj.2022110698

PMCID:: PMC9433938

Abstract Article PDF–9.3M

Select item 752370619.

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis

Katrin Tiemann, Carolina Garri, Sang Bok Lee, Paymaneh D. Malihi, Mincheol Park, Ruth M. Alvarez, Li Peng Yap, Parag Mallick, Jonathan E. Katz, Mitchell E. Gross, Kian Kani

Oncogene. Author manuscript; available in PMC 2020 Sep 29.

Published in final edited form as: Oncogene. 2019 Apr; 38(16): 3003–3018. Published online 2018 Dec 21. doi: 10.1038/s41388-018-0638-9

PMCID:: PMC7523706

Abstract Article PDF–2.3M

Select item 905602620.

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis

Fenglong Jiao, Clinton Yu, Andrew Wheat, Xiaorong Wang, Scott D. Rychnovsky, Lan Huang

Anal Chem. Author manuscript; available in PMC 2022 Apr 30.

Published in final edited form as: Anal Chem. 2022 Mar 15; 94(10): 4236–4242. Published online 2022 Mar 2. doi: 10.1021/acs.analchem.1c04485

PMCID:: PMC9056026

Abstract Article PDF–1.0M

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