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Select item 105632301.

Unveiling poly(rC)-binding protein 2 as the target protein for curcusone C against prostate cancer: mechanism validation through click chemistry-activity based proteomics profiling approach

Lan Huang, Buqing Ma, Chong Zhang, Jiaqi Shi, Rui Shen, Erci Zhang, Chenlei Lian, Cuifang Wang, Jieqing Liu

BMC Cancer. 2023; 23: 957. Published online 2023 Oct 9. doi: 10.1186/s12885-023-11467-0

PMCID:: PMC10563230

Abstract Article PDF–2.3M

Select item 54931272.

Heterogeneous ribonuclear protein E2 (hnRNP E2) is associated with TDP-43-immunoreactive neurites in Semantic Dementia but not with other TDP-43 pathological subtypes of Frontotemporal Lobar Degeneration

Yvonne S. Davidson, Andrew C. Robinson, Louis Flood, Sara Rollinson, Bridget C. Benson, Yasmine T. Asi, Anna Richardson, Matthew Jones, Julie S. Snowden, Stuart Pickering-Brown, Tammaryn Lashley, David M. A. Mann

Acta Neuropathol Commun. 2017; 5: 54. Published online 2017 Jun 30. doi: 10.1186/s40478-017-0454-4

PMCID:: PMC5493127

Abstract Article PDF–841K

Select item 39579573.

Inhibition of Poliovirus-Induced Cleavage of Cellular Protein PCBP2 Reduces the Levels of Viral RNA Replication

Amanda J. Chase, Sarah Daijogo, Bert L. Semler

J Virol. 2014 Mar; 88(6): 3192–3201. doi: 10.1128/JVI.02503-13

PMCID:: PMC3957957

Abstract Article PDF–1.4M

Select item 36139914.

Iron Homeostasis Regulates the Activity of the MicroRNA Pathway through Poly(C)-Binding Protein 2

Yujing Li, Li Lin, Zigang Li, Xuecheng Ye, Ke Xiong, Baikuntha Aryal, Zihui Xu, Zain Paroo, Qinghua Liu, Chuan He, Peng Jin

Cell Metab. Author manuscript; available in PMC 2013 Jun 6.

Published in final edited form as: Cell Metab. 2012 Jun 6; 15(6): 895–904. Published online 2012 May 24. doi: 10.1016/j.cmet.2012.04.021

PMCID:: PMC3613991

Abstract Article PDF–4.2M

Select item 31479985.

Poly(C)-Binding Protein 2 Interacts with Sequences Required for Viral Replication in the Hepatitis C Virus (HCV) 5′ Untranslated Region and Directs HCV RNA Replication through Circularizing the Viral Genome

Linya Wang, King-Song Jeng, Michael M. C. Lai

J Virol. 2011 Aug; 85(16): 7954–7964. doi: 10.1128/JVI.00339-11

PMCID:: PMC3147998

Abstract Article PDF–1.5M

Select item 27021776.

Protein-RNA Tethering: The Role of Poly(C) Binding Protein 2 in Poliovirus RNA Replication

Allyn Spear, Nidhi Sharma, James Bert Flanegan

Virology. Author manuscript; available in PMC 2009 Jun 26.

Published in final edited form as: Virology. 2008 May 10; 374(2): 280–291. Published online 2008 Feb 5. doi: 10.1016/j.virol.2007.12.039

PMCID:: PMC2702177

Abstract Article PDF–1.0M

Select item 25951387.

The linker domain of poly(rC) binding protein 2 is a major determinant in poliovirus cap-independent translation

Polen Sean, Joseph H. C. Nguyen, Bert L. Semler

Virology. Author manuscript; available in PMC 2009 Sep 1.

Published in final edited form as: Virology. 2008 Sep 1; 378(2): 243–253. Published online 2008 Jul 25. doi: 10.1016/j.virol.2008.05.007

PMCID:: PMC2595138

Abstract Article PDF–3.0M

Select item 25689038.

Structure of a Construct of a Human Poly(C)-binding Protein Containing the First and Second KH Domains Reveals Insights into Its Regulatory Mechanisms

Zhihua Du, Sebastian Fenn, Richard Tjhen, Thomas L. James

J Biol Chem. 2008 Oct 17; 283(42): 28757–28766. doi: 10.1074/jbc.M803046200

PMCID:: PMC2568903

Abstract Article PDF–939K

Select item 22482649.

Identification of PCBP2, a facilitator of IRES-mediated translation, as a novel constituent of stress granules and processing bodies

Ken Fujimura, Fumi Kano, Masayuki Murata

RNA. 2008 Mar; 14(3): 425–431. doi: 10.1261/rna.780708

PMCID:: PMC2248264

Abstract Article PDF–567K

Select item 195142510.

Cellular Protein Modification by Poliovirus: the Two Faces of Poly(rC)-Binding Protein

Rushika Perera, Sarah Daijogo, Brandon L. Walter, Joseph H. C. Nguyen, Bert L. Semler

J Virol. 2007 Sep; 81(17): 8919–8932. Published online 2007 Jun 20. doi: 10.1128/JVI.01013-07

PMCID:: PMC1951425

Abstract Article PDF–591K

Select item 189492811.

X-ray crystallographic and NMR studies of protein–protein and protein–nucleic acid interactions involving the KH domains from human poly(C)-binding protein-2

Zhihua Du, John K. Lee, Sebastian Fenn, Richard Tjhen, Robert M. Stroud, Thomas L. James

RNA. 2007 Jul; 13(7): 1043–1051. doi: 10.1261/rna.410107

PMCID:: PMC1894928

Abstract Article PDF–630K

Select item 188566112.

Crystal structure of the third KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.6 Å resolution

Sebastian Fenn, Zhihua Du, John K. Lee, Richard Tjhen, Robert M. Stroud, Thomas L. James

Nucleic Acids Res. 2007 Apr; 35(8): 2651–2660. Published online 2007 Apr 10. doi: 10.1093/nar/gkm139

PMCID:: PMC1885661

Abstract Article PDF–1.0M

Select item 19189213.

Requirement of poly(rC) binding protein 2 for translation of poliovirus RNA.

L B Blyn, J S Towner, B L Semler, E Ehrenfeld

J Virol. 1997 Aug; 71(8): 6243–6246. doi: 10.1128/jvi.71.8.6243-6246.1997

PMCID:: PMC191892

Summary PDF–1.3M

Select item 1071156514.

Binding of microRNA-122 to the hepatitis C virus 5′ untranslated region modifies interactions with poly(C) binding protein 2 and the NS5B viral polymerase

Seth Scott, You Li, Oya Bermek, Jack D Griffith, Stanley M Lemon, Kyung H Choi

Nucleic Acids Res. 2023 Dec 11; 51(22): 12397–12413. Published online 2023 Nov 6. doi: 10.1093/nar/gkad1000

PMCID:: PMC10711565

Abstract Article PDF–2.1M

Select item 894320615.

PCBP2 maintains antiviral signaling homeostasis by regulating cGAS enzymatic activity via antagonizing its condensation

Haiyan Gu, Jing Yang, Jiayu Zhang, Ying Song, Yao Zhang, Pengfei Xu, Yuanxiang Zhu, Liangliang Wang, Pengfei Zhang, Lin Li, Dahua Chen, Qinmiao Sun

Nat Commun. 2022; 13: 1564. Published online 2022 Mar 23. doi: 10.1038/s41467-022-29266-9

PMCID:: PMC8943206

Abstract Article PDF–4.1M

Select item 870800516.

Poly(C)-binding Protein 2 Regulates the p53 Expression via Interactions with the 5′-Terminal Region of p53 mRNA

Damian M. Janecki, Agata Swiatkowska, Joanna Szpotkowska, Anna Urbanowicz, Martyna Kabacińska, Kamil Szpotkowski, Jerzy Ciesiołka

Int J Mol Sci. 2021 Dec; 22(24): 13306. Published online 2021 Dec 10. doi: 10.3390/ijms222413306

PMCID:: PMC8708005

Abstract Article PDF–4.4M

Select item 744348917.

PCBP1 and PCBP2 both bind heavily oxidized RNA but cause opposing outcomes, suppressing or increasing apoptosis under oxidative conditions

Takashi Ishii, Tatsuhiro Igawa, Hiroshi Hayakawa, Tsugumi Fujita, Mutsuo Sekiguchi, Yusaku Nakabeppu

J Biol Chem. 2020 Aug 21; 295(34): 12247–12261. Published online 2020 Jul 9. doi: 10.1074/jbc.RA119.011870

Correction in:: J Biol Chem. 2021 Dec; 297(6): 101447.

PMCID:: PMC7443489

Abstract Article PDF–3.6M

Select item 718322118.

The T1D-associated lncRNA Lnc13 modulates human pancreatic β cell inflammation by allele-specific stabilization of STAT1 mRNA

Itziar Gonzalez-Moro, Ane Olazagoitia-Garmendia, Maikel L. Colli, Nadia Cobo-Vuilleumier, Thomas S. Postler, Lorella Marselli, Piero Marchetti, Sankar Ghosh, Benoit R. Gauthier, Decio L. Eizirik, Ainara Castellanos-Rubio, Izortze Santin

Proc Natl Acad Sci U S A. 2020 Apr 21; 117(16): 9022–9031. Published online 2020 Apr 13. doi: 10.1073/pnas.1914353117

PMCID:: PMC7183221

Abstract Article PDF–1.2M

Select item 718239719.

Nutlin-Induced Apoptosis Is Specified by a Translation Program Regulated by PCBP2 and DHX30

Dario Rizzotto, Sara Zaccara, Annalisa Rossi, Matthew D. Galbraith, Zdenek Andrysik, Ahwan Pandey, Kelly D. Sullivan, Alessandro Quattrone, Joaquín M. Espinosa, Erik Dassi, Alberto Inga

Cell Rep. Author manuscript; available in PMC 2020 Apr 24.

Published in final edited form as: Cell Rep. 2020 Mar 31; 30(13): 4355–4369.e6. doi: 10.1016/j.celrep.2020.03.011

PMCID:: PMC7182397

Abstract Article PDF–2.4M

Select item 501612920.

Iron Export through the Transporter Ferroportin 1 Is Modulated by the Iron Chaperone PCBP2

Izumi Yanatori, Des R. Richardson, Kiyoshi Imada, Fumio Kishi

J Biol Chem. 2016 Aug 12; 291(33): 17303–17318. Published online 2016 Jun 14. doi: 10.1074/jbc.M116.721936

PMCID:: PMC5016129

Abstract Article PDF–3.9M

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PMC Links for Gene (Select 5094) (224)
PMC
PREDICTED: Xenopus laevis scribbled planar cell polarity protein S homeolog (scr...
PREDICTED: Xenopus laevis scribbled planar cell polarity protein S homeolog (scrib.S), transcript variant X1, mRNA
gi|2038243082|ref|XM_041568062.1|

Nucleotide
protein scribble homolog isoform X10 [Xenopus laevis]
protein scribble homolog isoform X10 [Xenopus laevis]
gi|2038243123|ref|XP_041424006.1|

Protein
PREDICTED: Xenopus laevis scribbled planar cell polarity protein S homeolog (scr...
PREDICTED: Xenopus laevis scribbled planar cell polarity protein S homeolog (scrib.S), transcript variant X31, misc_RNA
gi|2038243202|ref|XR_005962331.1|

Nucleotide
protein scribble homolog isoform X13 [Xenopus laevis]
protein scribble homolog isoform X13 [Xenopus laevis]
gi|2038243135|ref|XP_041424009.1|

Protein

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