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Select item 89800721.

Partitioning defective 6 homolog alpha (PARD6A) promotes epithelial–mesenchymal transition via integrin β1-ILK-SNAIL1 pathway in ovarian cancer

Ziwen Lu, Sirui Yuan, Lingling Ruan, Zhigang Tu, Hanqing Liu

Cell Death Dis. 2022 Apr; 13(4): 304. Published online 2022 Apr 5. doi: 10.1038/s41419-022-04756-2

PMCID:: PMC8980072

Abstract Article PDF–5.0M

Select item 66747302.

mPar6α Controls Neuronal Migration

David J. Solecki, Eve-Ellen Govek, Mary E. Hatten

J Neurosci. 2006 Oct 18; 26(42): 10624–10625. doi: 10.1523/JNEUROSCI.4060-06.2006

PMCID:: PMC6674730

Abstract Article PDF–78K

Select item 43859603.

TGFβ-induced phosphorylation of Par6 promotes migration and invasion in prostate cancer cells

Y Mu, G Zang, U Engström, C Busch, M Landström

Br J Cancer. 2015 Mar 31; 112(7): 1223–1231. Published online 2015 Mar 10. doi: 10.1038/bjc.2015.71

PMCID:: PMC4385960

Abstract Article PDF–2.2M

Select item 29487554.

The Polarity Protein Par6 Induces Cell Proliferation and Is Overexpressed in Breast Cancer

Marissa E. Nolan, Victoria Aranda, Sangjun Lee, Balasubramanian Lakshmi, Srinjan Basu, D. Craig Allred, Senthil K. Muthuswamy

Cancer Res. Author manuscript; available in PMC 2010 Oct 3.

Published in final edited form as: Cancer Res. 2008 Oct 15; 68(20): 8201–8209. doi: 10.1158/0008-5472.CAN-07-6567

PMCID:: PMC2948755

Abstract Article PDF–1.8M

Select item 21750815.

Rit Mutants Confirm Role of MEK/ERK Signaling in Neuronal Differentiation and Reveal Novel Par6 Interaction

Jennifer L. Rudolph, Geng-Xian Shi, Eda Erdogan, Alan P. Fields, Douglas A. Andres

Biochim Biophys Acta. Author manuscript; available in PMC 2008 Jan 7.

Published in final edited form as: Biochim Biophys Acta. 2007 Dec; 1773(12): 1793–1800. Published online 2007 Oct 9. doi: 10.1016/j.bbamcr.2007.09.008

PMCID:: PMC2175081

Abstract Article PDF–750K

Select item 19000686.

Characterization of Mammalian Par 6 as a Dual-Location Protein

Erin G. Cline, W. James Nelson

Mol Cell Biol. 2007 Jun; 27(12): 4431–4443. Published online 2007 Apr 9. doi: 10.1128/MCB.02235-06

PMCID:: PMC1900068

Abstract Article PDF–2.7M

Select item 111054187.

PAR3–PAR6–atypical PKC polarity complex proteins in neuronal polarization

Sophie M. Hapak, Carla V. Rothlin, Sourav Ghosh

Cell Mol Life Sci. 2018 Aug; 75(15): 2735–2761. Published online 2018 Apr 25. doi: 10.1007/s00018-018-2828-6

PMCID:: PMC11105418

Abstract Article PDF–2.5M

Select item 62240918.

A Tuba/Cdc42/Par6A complex is required to ensure singularity in apical domain formation during enterocyte polarization

Lucas J. M. Bruurs, Mirjam C. van der Net, Susan Zwakenberg, Fried J. T. Zwartkruis, Johannes L. Bos

PLoS One. 2018; 13(11): e0207159. Published online 2018 Nov 8. doi: 10.1371/journal.pone.0207159

PMCID:: PMC6224091

Abstract Article PDF–2.3M

Select item 36230799.

Atypical Protein Kinase C Phosphorylates Par6 and Facilitates Transforming Growth Factor β-Induced Epithelial-to-Mesenchymal Transition

Adrian Gunaratne, Boun L. Thai, Gianni M. Di Guglielmo

Mol Cell Biol. 2013 Mar; 33(5): 874–886. doi: 10.1128/MCB.00837-12

PMCID:: PMC3623079

Abstract Article PDF–2.5M

Select item 367512910.

A Genome-Wide Screen of CREB Occupancy Identifies the RhoA Inhibitors Par6C and Rnd3 as Regulators of BDNF-Induced Synaptogenesis

Adam Lesiak, Carl Pelz, Hideaki Ando, Mingyan Zhu, Monika Davare, Talley J. Lambert, Katelin F. Hansen, Karl Obrietan, Suzanne M. Appleyard, Soren Impey, Gary A. Wayman

PLoS One. 2013; 8(6): e64658. Published online 2013 Jun 6. doi: 10.1371/journal.pone.0064658

PMCID:: PMC3675129

Abstract Article PDF–11M

Select item 301834911.

Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6

Cristina Hidalgo-Carcedo, Steven Hooper, Shahid I. Chaudhry, Peter Williamson, Kevin Harrington, Birgit Leitinger, Erik Sahai

Nat Cell Biol. Author manuscript; available in PMC 2011 Jul 1.

Published in final edited form as: Nat Cell Biol. 2011 Jan; 13(1): 49–58. Published online 2010 Dec 19. doi: 10.1038/ncb2133

PMCID:: PMC3018349

Abstract Article PDF–2.7M

Select item 502194212.

Hook2, a microtubule-binding protein, interacts with Par6α and controls centrosome orientation during polarized cell migration

Emilie Pallesi-Pocachard, Elsa Bazellieres, Annelise Viallat-Lieutaud, Marie-Hélène Delgrossi, Magali Barthelemy-Requin, André Le Bivic, Dominique Massey-Harroche

Sci Rep. 2016; 6: 33259. Published online 2016 Sep 14. doi: 10.1038/srep33259

PMCID:: PMC5021942

Abstract Article PDF–1.6M

Select item 491946313.

Protein Scaffolds Control Localized Protein Kinase Cζ Activity

Irene S. Tobias, Alexandra C. Newton

J Biol Chem. 2016 Jun 24; 291(26): 13809–13822. Published online 2016 May 3. doi: 10.1074/jbc.M116.729483

PMCID:: PMC4919463

Abstract Article PDF–2.0M

Select item 272901414.

A role for the TGFβ-Par6 polarity pathway in breast cancer progression

Alicia M. Viloria-Petit, Laurent David, Jun Yong Jia, Tuba Erdemir, Anita L. Bane, Dushanthi Pinnaduwage, Luba Roncari, Masahiro Narimatsu, Rohit Bose, Jason Moffat, John W. Wong, Robert S. Kerbel, Frances P. O'Malley, Irene L. Andrulis, Jeffrey L. Wrana

Proc Natl Acad Sci U S A. 2009 Aug 18; 106(33): 14028–14033. Published online 2009 Aug 10. doi: 10.1073/pnas.0906796106

PMCID:: PMC2729014

Abstract Article PDF–1.8M

Select item 36313715.

CRB3 Binds Directly to Par6 and Regulates the Morphogenesis of the Tight Junctions in Mammalian Epithelial Cells

Céline Lemmers, Didier Michel, Lydie Lane-Guermonprez, Marie-Hélène Delgrossi, Emmanuelle Médina, Jean-Pierre Arsanto, André Le Bivic

Mol Biol Cell. 2004 Mar; 15(3): 1324–1333. doi: 10.1091/mbc.E03-04-0235

PMCID:: PMC363137

Abstract Article PDF–730K

Select item 15034316.

Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6

Sarah M. Garrard, Christopher T. Capaldo, Lin Gao, Michael K. Rosen, Ian G. Macara, Diana R. Tomchick

EMBO J. 2003 Mar 3; 22(5): 1125–1133. doi: 10.1093/emboj/cdg110

PMCID:: PMC150343

Abstract Article PDF–383K

Select item 448602017.

Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFa in glioblastoma

Yael Kusne, Eugenio A. Carrera-Silva, Anthony S. Perry, Elisabeth J. Rushing, Edward K. Mandell, Justin D. Dietrich, Andrea E. Errasti, Daniel Gibbs, Michael E. Berens, Joseph C. Loftus, Christopher Hulme, Weiwei Yang, Zhimin Lu, Kenneth Aldape, Nader Sanai, Carla V. Rothlin, Sourav Ghosh

Sci Signal. Author manuscript; available in PMC 2015 Jun 30.

Published in final edited form as: Sci Signal. 2014 Aug 12; 7(338): ra75. Published online 2014 Aug 12. doi: 10.1126/scisignal.2005196