PMC Links for Gene (Select 50833) - PMC

Select item 87147771.

TAS2R16 Activation Suppresses LPS-Induced Cytokine Expression in Human Gingival Fibroblasts

Zhiyan Zhou, Ranhui Xi, Jiaxin Liu, Xian Peng, Lei Zhao, Xuedong Zhou, Jiyao Li, Xin Zheng, Xin Xu

Front Immunol. 2021; 12: 726546. Published online 2021 Dec 15. doi: 10.3389/fimmu.2021.726546

PMCID:: PMC8714777

Abstract Article PDF–7.6M

Select item 75827252.

Suppression of hTAS2R16 Signaling by Umami Substances

Mee-Ra Rhyu, Yiseul Kim, Takumi Misaka

Int J Mol Sci. 2020 Oct; 21(19): 7045. Published online 2020 Sep 24. doi: 10.3390/ijms21197045

PMCID:: PMC7582725

Abstract Article PDF–2.0M

Select item 65601323.

Dual binding mode of “bitter sugars” to their human bitter taste receptor target

Fabrizio Fierro, Alejandro Giorgetti, Paolo Carloni, Wolfgang Meyerhof, Mercedes Alfonso-Prieto

Sci Rep. 2019; 9: 8437. Published online 2019 Jun 11. doi: 10.1038/s41598-019-44805-z

PMCID:: PMC6560132

Abstract Article PDF–1.9M

Select item 56030474.

Association between polymorphisms of TAS2R16 and susceptibility to colorectal cancer

Jonathan Barontini, Marco Antinucci, Sergio Tofanelli, Maurizio Cammalleri, Massimo Dal Monte, Federica Gemignani, Pavel Vodicka, Roberto Marangoni, Ludmila Vodickova, Juozas Kupcinskas, Veronika Vymetalkova, Asta Forsti, Federico Canzian, Angelika Stein, Victor Moreno, Nicola Mastrodonato, Francesca Tavano, Anna Panza, Roberto Barale, Stefano Landi, Daniele Campa

BMC Gastroenterol. 2017; 17: 104. Published online 2017 Sep 15. doi: 10.1186/s12876-017-0659-9

PMCID:: PMC5603047

Abstract Article PDF–386K

Select item 42830635.

Principal Component Analysis of Binding Energies for Single-Point Mutants of hT2R16 Bound to an Agonist Correlate with Experimental Mutant Cell Response

Derek E. Chen, Darryl L. Willick, Joseph B. Ruckel, Wely B. Floriano

J Comput Biol. 2015 Jan 1; 22(1): 37–53. doi: 10.1089/cmb.2014.0192

PMCID:: PMC4283063

Abstract Article PDF–1.5M

Select item 40751716.

Limited Evidence for Adaptive Evolution and Functional Effect of Allelic Variation at rs702424 in the Promoter of the TAS2R16 Bitter Taste Receptor Gene in Africa

Michael C. Campbell, Alessia Ranciaro, Daniel Zinshteyn, Renata Rawlings-Goss, Jibril Hirbo, Simon Thompson, Dawit Woldemeskel, Alain Froment, Sabah A. Omar, Jean-Marie Bodo, Thomas Nyambo, Gurja Belay, Dennis Drayna, Paul A.S. Breslin, Sarah A. Tishkoff

J Hum Genet. Author manuscript; available in PMC 2014 Dec 1.

Published in final edited form as: J Hum Genet. 2014 Jun; 59(6): 349–352. Published online 2014 May 1. doi: 10.1038/jhg.2014.29

PMCID:: PMC4075171

Abstract Article PDF–411K

Select item 39070567.

Origin and Differential Selection of Allelic Variation at TAS2R16 Associated with Salicin Bitter Taste Sensitivity in Africa

Michael C. Campbell, Alessia Ranciaro, Daniel Zinshteyn, Renata Rawlings-Goss, Jibril Hirbo, Simon Thompson, Dawit Woldemeskel, Alain Froment, Joseph B. Rucker, Sabah A. Omar, Jean-Marie Bodo, Thomas Nyambo, Gurja Belay, Dennis Drayna, Paul A.S. Breslin, Sarah A. Tishkoff

Mol Biol Evol. 2014 Feb; 31(2): 288–302. Published online 2013 Oct 30. doi: 10.1093/molbev/mst211

PMCID:: PMC3907056

Abstract Article PDF–1.0M

Select item 34877258.

Bitter Taste Receptor Polymorphisms and Human Aging

Daniele Campa, Francesco De Rango, Maura Carrai, Paolina Crocco, Alberto Montesanto, Federico Canzian, Giuseppina Rose, Cosmeri Rizzato, Giuseppe Passarino, Roberto Barale

PLoS One. 2012; 7(11): e45232. Published online 2012 Nov 2. doi: 10.1371/journal.pone.0045232

PMCID:: PMC3487725

Abstract Article PDF–532K

Select item 29347019.

Characterization of the β-d-Glucopyranoside Binding Site of the Human Bitter Taste Receptor hTAS2R16

Takanobu Sakurai, Takumi Misaka, Masaji Ishiguro, Katsuyoshi Masuda, Taishi Sugawara, Keisuke Ito, Takuya Kobayashi, Shinji Matsuo, Yoshiro Ishimaru, Tomiko Asakura, Keiko Abe

J Biol Chem. 2010 Sep 3; 285(36): 28373–28378. Published online 2010 Jul 6. doi: 10.1074/jbc.M110.144444

PMCID:: PMC2934701

Abstract Article PDF–1.2M

Select item 138020710.

Functional Variant in a Bitter-Taste Receptor (hTAS2R16) Influences Risk of Alcohol Dependence

Anthony L. Hinrichs, Jen C. Wang, Bernd Bufe, Jennifer M. Kwon, John Budde, Rebecca Allen, Sarah Bertelsen, Whitney Evans, Danielle Dick, John Rice, Tatiana Foroud, John Nurnberger, Jay A. Tischfield, Samuel Kuperman, Raymond Crowe, Victor Hesselbrock, Marc Schuckit, Laura Almasy, Bernice Porjesz, Howard J. Edenberg, Henri Begleiter, Wolfgang Meyerhof, Laura J. Bierut, Alison M. Goate

Am J Hum Genet. 2006 Jan; 78(1): 103–111. Published online 2005 Nov 21. doi: 10.1086/499253