PMC Links for Gene (Select 5078) - PMC

Links from Gene

Items: 1 to 20 of 28

<< First< Prev

Page of 2

Select item 105423691.

PAX4 loss of function increases diabetes risk by altering human pancreatic endocrine cell development

Hwee Hui Lau, Nicole A. J. Krentz, Fernando Abaitua, Marta Perez-Alcantara, Jun-Wei Chan, Jila Ajeian, Soumita Ghosh, Yunkyeong Lee, Jing Yang, Swaraj Thaman, Benoite Champon, Han Sun, Alokkumar Jha, Shawn Hoon, Nguan Soon Tan, Daphne Su-Lyn Gardner, Shih Ling Kao, E. Shyong Tai, Anna L. Gloyn, Adrian Kee Keong Teo

Nat Commun. 2023; 14: 6119. Published online 2023 Sep 30. doi: 10.1038/s41467-023-41860-z

PMCID:: PMC10542369

Abstract Article PDF–2.2M

Select item 101794552.

Pax4 in Health and Diabetes

Jenna Ko, Vivian A. Fonseca, Hongju Wu

Int J Mol Sci. 2023 May; 24(9): 8283. Published online 2023 May 5. doi: 10.3390/ijms24098283

PMCID:: PMC10179455

Abstract Article PDF–716K

Select item 60113263.

The rs10229583 polymorphism near paired box gene 4 is associated with gestational diabetes mellitus in Chinese women

Tianyi Xu, Yiru Shi, Jiangbo Liu, Yun Liu, Ailin Zhu, Cui Xie, Yan Zhang, Yan Chen, Lirong Ren

J Int Med Res. 2018 Jan; 46(1): 115–121. Published online 2017 Jul 21. doi: 10.1177/0300060517714934

PMCID:: PMC6011326

Abstract Article PDF–155K

Select item 45941994.

Overexpression of PAX4 reduces glucagon expression in differentiating hESCs

Blair K Gage, Robert K Baker, Timothy J Kieffer

Islets. 2014; 6(2): e29236. Published online 2014 Jun 17. doi: 10.4161/isl.29236

PMCID:: PMC4594199

Abstract Article PDF–3.3M

Select item 22621355.

PAX4 Enhances Beta-Cell Differentiation of Human Embryonic Stem Cells

Chee Gee Liew, Nadia N. Shah, Sarah J. Briston, Ruth M. Shepherd, Cheen Peen Khoo, Mark J. Dunne, Harry D. Moore, Karen E. Cosgrove, Peter W. Andrews

PLoS One. 2008; 3(3): e1783. Published online 2008 Mar 12. doi: 10.1371/journal.pone.0001783

PMCID:: PMC2262135

Abstract Article PDF–533K

Select item 10512756.

Organisation of the human PAX4 gene and its exclusion as a candidate for the Wolcott-Rallison syndrome.

D T Bonthron, N Dunlop, D G Barr, A A El Sanousi, L I Al-Gazali

J Med Genet. 1998 Apr; 35(4): 288–292. doi: 10.1136/jmg.35.4.288

PMCID:: PMC1051275

Summary Page Browse PDF–1.3M

Select item 61451787.

PAX4 gene variations predispose to ketosis-prone diabetes

Franck Mauvais-Jarvis, Stuart B. Smith, Cédric Le May, Suzanne M. Leal, Jean-François Gautier, Mariam Molokhia, Jean-Pierre Riveline, Arun S. Rajan, Jean-Philippe Kevorkian, Sumei Zhang, Patrick Vexiau, Michael S. German, Christian Vaisse

Hum Mol Genet. Author manuscript; available in PMC 2018 Sep 19.

Published in final edited form as: Hum Mol Genet. 2004 Dec 15; 13(24): 3151–3159. Published online 2004 Oct 27. doi: 10.1093/hmg/ddh341

PMCID:: PMC6145178

Abstract Article PDF–476K

Select item 28042618.

No association of the IRS1 and PAX4 genes with type I diabetes

R Bergholdt, C Brorsson, B Boehm, G Morahan, F Pociot, the Type I Diabetes Genetics Consortium

Genes Immun. Author manuscript; available in PMC 2010 Jan 11.

Published in final edited form as: Genes Immun. 2009 Dec; 10(Suppl 1): S49–S53. doi: 10.1038/gene.2009.91

PMCID:: PMC2804261

Abstract Article PDF–720K

Select item 21726189.

The diabetes-linked transcription factor PAX4 promotes β-cell proliferation and survival in rat and human islets

Thierry Brun, Isobel Franklin, Luc St-Onge, Anna Biason-Lauber, Eugene J. Schoenle, Claes B. Wollheim, Benoit R. Gauthier

J Cell Biol. 2004 Dec 20; 167(6): 1123–1135. doi: 10.1083/jcb.200405148

PMCID:: PMC2172618

Abstract Article PDF–2.3M

Select item 904412610.

Evaluation of Evidence for Pathogenicity Demonstrates That BLK, KLF11, and PAX4 Should Not Be Included in Diagnostic Testing for MODY

Thomas W. Laver, Matthew N. Wakeling, Olivia Knox, Kevin Colclough, Caroline F. Wright, Sian Ellard, Andrew T. Hattersley, Michael N. Weedon, Kashyap A. Patel

Diabetes. 2022 May; 71(5): 1128–1136. Published online 2022 Feb 2. doi: 10.2337/db21-0844

PMCID:: PMC9044126

Abstract Article PDF–875K

Select item 826631511.

Transcription factor PAX4 facilitates gastric cancer progression through interacting with miR-27b-3p/Grb2 axis

Yan Zhang, Li Ding, Qingfeng Ni, Ran Tao, Jun Qin

Aging (Albany NY) 2021 Jun 30; 13(12): 16786–16803. Published online 2021 Jun 23. doi: 10.18632/aging.203214

PMCID:: PMC8266315

Abstract Article PDF–1.4M

Select item 375496812.

Both PAX4 and MAFA Are Expressed in a Substantial Proportion of Normal Human Pancreatic Alpha Cells and Deregulated in Patients with Type 2 Diabetes

Rémy Bonnavion, Rami Jaafar, Julie Kerr-Conte, Fouzia Assade, Esther van Stralen, Emmanuelle Leteurtre, Célio Pouponnot, Sofia Gargani, François Pattou, Philippe Bertolino, Martine Cordier-Bussat, Jieli Lu, Chang Xian Zhang

PLoS One. 2013; 8(8): e72194. Published online 2013 Aug 27. doi: 10.1371/journal.pone.0072194

PMCID:: PMC3754968

Abstract Article PDF–23M

Select item 364868713.

Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4

R. C. W. Ma, C. Hu, C. H. Tam, R. Zhang, P. Kwan, T. F. Leung, G. N. Thomas, M. J. Go, K. Hara, X. Sim, J. S. K. Ho, C. Wang, H. Li, L. Lu, Y. Wang, J. W. Li, Y. Wang, V. K. L. Lam, J. Wang, W. Yu, Y. J. Kim, D. P. Ng, H. Fujita, K. Panoutsopoulou, A. G. Day-Williams, H. M. Lee, A. C. W. Ng, Y-J. Fang, A. P. S. Kong, F. Jiang, X. Ma, X. Hou, S. Tang, J. Lu, T. Yamauchi, S. K. W. Tsui, J. Woo, P. C. Leung, X. Zhang, N. L. S. Tang, H. Y. Sy, J. Liu, T. Y. Wong, J. Y. Lee, S. Maeda, G. Xu, S. S. Cherny, T. F. Chan, M. C. Y. Ng, K. Xiang, A. P. Morris, DIAGRAM Consortium, S. Keildson, The MuTHER Consortium, R. Hu, L. Ji, X. Lin, Y. S. Cho, T. Kadowaki, E. S. Tai, E. Zeggini, M. I. McCarthy, K. L. Hon, L. Baum, B. Tomlinson, W. Y. So, Y. Bao, J. C. N. Chan, W. Jia

Diabetologia. 2013; 56(6): 1291–1305. Published online 2013 Mar 27. doi: 10.1007/s00125-013-2874-4

PMCID:: PMC3648687

Abstract Article PDF–379K

Select item 278873114.

Candidate gene polymorphisms for diabetes mellitus, cardiovascular disease and cancer are associated with longevity in Koreans

Ji Wan Park, Yong Ick Ji, Yoon-Ho Choi, Mi-Yeon Kang, Eunhyun Jung, Se Young Cho, Hee-Youn Cho, Byung Kyu Kang, Yoo Sook Joung, Duk-Hwan Kim, Sang Chul Park, Joobae Park

Exp Mol Med. 2009 Nov 30; 41(11): 772–781. Published online 2009 Nov 30. doi: 10.3858/emm.2009.41.11.083

PMCID:: PMC2788731

Abstract Article PDF–618K

Select item 267109615.

A−β− Subtype of Ketosis-Prone Diabetes Is Not Predominantly a Monogenic Diabetic Syndrome

Wade C. Haaland, Diane I. Scaduto, Mario R. Maldonado, Dena L. Mansouri, Ramaswami Nalini, Dinakar Iyer, Sanjeet Patel, Anu Guthikonda, Christiane S. Hampe, Ashok Balasubramanyam, Michael L. Metzker

Diabetes Care. 2009 May; 32(5): 873–877. Published online 2009 Feb 19. doi: 10.2337/dc08-1529

PMCID:: PMC2671096

Abstract Article PDF–83K

Select item 358239816.

Meta-analysis of genome-wide association studies identifies 8 new loci for type 2 diabetes in East Asians

Yoon Shin Cho, Chien-Hsiun Chen, Cheng Hu, Jirong Long, Rick Twee Hee Ong, Xueling Sim, Fumihiko Takeuchi, Ying Wu, Min Jin Go, Toshimasa Yamauchi, Yi-Cheng Chang, Soo Heon Kwak, Ronald C.W. Ma, Ken Yamamoto, Linda S. Adair, Tin Aung, Qiuyin Cai, Li-Ching Chang, Yuan-Tsong Chen, Yutang Gao, Frank B. Hu, Hyung-Lae Kim, Sangsoo Kim, Young Jin Kim, Jeannette Jen-Mai Lee, Nanette R. Lee, Yun Li, Jian Jun Liu, Wei Lu, Jiro Nakamura, Eitaro Nakashima, Daniel Peng-Keat Ng, Wan Ting Tay, Fuu-Jen Tsai, Tien Yin Wong, Mitsuhiro Yokota, Wei Zheng, Rong Zhang, Congrong Wang, Wing Yee So, Keizo Ohnaka, Hiroshi Ikegami, Kazuo Hara, Young Min Cho, Nam H Cho, Tien-Jyun Chang, Yuqian Bao, Åsa K. Hedman, Andrew P. Morris, Mark I. McCarthy, DIAGRAM consortium, MuTHER consortium, Ryoichi Takayanagi, Kyong Soo Park, Weiping Jia, Lee-Ming Chuang, Juliana C.N. Chan, Shiro Maeda, Takashi Kadowaki, Jong-Young Lee, Jer-Yuarn Wu, Yik Ying Teo, E Shyong Tai, Xiao Ou Shu, Karen L. Mohlke, Norihiro Kato, Bok-Ghee Han, Mark Seielstad

Nat Genet. Author manuscript; available in PMC 2013 Feb 26.

Published in final edited form as: Nat Genet. 2011 Dec 11; 44(1): 67–72. Published online 2011 Dec 11. doi: 10.1038/ng.1019

PMCID:: PMC3582398

Abstract Article PDF–2.4M

Select item 533762117.

Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis

M Kamran, Z-J Long, D Xu, S-S Lv, B Liu, C-L Wang, J Xu, E W-F Lam, Q Liu

Oncogenesis. 2017 Feb; 6(2): e298. Published online 2017 Feb 20. doi: 10.1038/oncsis.2016.80

PMCID:: PMC5337621

Abstract Article PDF–2.8M

Select item 288296118.

Human Chromosome 7: DNA Sequence and Biology

Stephen W. Scherer, Joseph Cheung, Jeffrey R. MacDonald, Lucy R. Osborne, Kazuhiko Nakabayashi, Jo-Anne Herbrick, Andrew R. Carson, Layla Parker-Katiraee, Jennifer Skaug, Razi Khaja, Junjun Zhang, Alexander K. Hudek, Martin Li, May Haddad, Gavin E. Duggan, Bridget A. Fernandez, Emiko Kanematsu, Simone Gentles, Constantine C. Christopoulos, Sanaa Choufani, Dorota Kwasnicka, Xiangqun H. Zheng, Zhongwu Lai, Deborah Nusskern, Qing Zhang, Zhiping Gu, Fu Lu, Susan Zeesman, Malgorzata J. Nowaczyk, Ikuko Teshima, David Chitayat, Cheryl Shuman, Rosanna Weksberg, Elaine H. Zackai, Theresa A. Grebe, Sarah R. Cox, Susan J. Kirkpatrick, Nazneen Rahman, Jan M. Friedman, Henry H. Q. Heng, Pier Giuseppe Pelicci, Francesco Lo-Coco, Elena Belloni, Lisa G. Shaffer, Barbara Pober, Cynthia C. Morton, James F. Gusella, Gail A. P. Bruns, Bruce R. Korf, Bradley J. Quade, Azra H. Ligon, Heather Ferguson, Anne W. Higgins, Natalia T. Leach, Steven R. Herrick, Emmanuelle Lemyre, Chantal G. Farra, Hyung-Goo Kim, Anne M. Summers, Karen W. Gripp, Wendy Roberts, Peter Szatmari, Elizabeth J. T. Winsor, Karl-Heinz Grzeschik, Ahmed Teebi, Berge A. Minassian, Juha Kere, Lluis Armengol, Miguel Angel Pujana, Xavier Estivill, Michael D. Wilson, Ben F. Koop, Sabrina Tosi, Gudrun E. Moore, Andrew P. Boright, Eitan Zlotorynski, Batsheva Kerem, Peter M. Kroisel, Erwin Petek, David G. Oscier, Sarah J. Mould, Hartmut Döhner, Konstanze Döhner, Johanna M. Rommens, John B. Vincent, J. Craig Venter, Peter W. Li, Richard J. Mural, Mark D. Adams, Lap-Chee Tsui

Science. Author manuscript; available in PMC 2010 Jun 9.

Published in final edited form as: Science. 2003 May 2; 300(5620): 767–772. Published online 2003 Apr 10. doi: 10.1126/science.1083423

PMCID:: PMC2882961

Abstract Article PDF–1.2M

Select item 800904819.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 444121520.

Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders

Nidhi Sahni, Song Yi, Mikko Taipale, Juan I. Fuxman Bass, Jasmin Coulombe-Huntington, Fan Yang, Jian Peng, Jochen Weile, Georgios I. Karras, Yang Wang, István A. Kovács, Atanas Kamburov, Irina Krykbaeva, Mandy H. Lam, George Tucker, Vikram Khurana, Amitabh Sharma, Yang-Yu Liu, Nozomu Yachie, Quan Zhong, Yun Shen, Alexandre Palagi, Adriana San-Miguel, Changyu Fan, Dawit Balcha, Amelie Dricot, Daniel M. Jordan, Jennifer M. Walsh, Akash A. Shah, Xinping Yang, Ani Stoyanova, Alex Leighton, Michael A. Calderwood, Yves Jacob, Michael E. Cusick, Kourosh Salehi-Ashtiani, Luke J. Whitesell, Shamil Sunyaev, Bonnie Berger, Albert-László Barabási, Benoit Charloteaux, David E. Hill, Tong Hao, Frederick P. Roth, Yu Xia, Albertha J.M. Walhout, Susan Lindquist, Marc Vidal

Cell. Author manuscript; available in PMC 2016 Apr 23.

Published in final edited form as: Cell. 2015 Apr 23; 161(3): 647–660. doi: 10.1016/j.cell.2015.04.013

PMCID:: PMC4441215

Abstract Article PDF–1.2M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from Gene

Items: 1 to 20 of 28

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity