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Items: 1 to 20 of 101

1.
Causal Role for Neutrophil Elastase in Thoracic Aortic Dissection in Mice
Mei Yang, Xinmiao Zhou, Stuart W.A. Pearce, Zhisheng Yang, Qishan Chen, Kaiyuan Niu, Chenxin Liu, Jun Luo, Dan Li, Yue Shao, Cheng Zhang, Dan Chen, Qingchen Wu, Pedro R. Cutillas, Lin Zhao, Qingzhong Xiao, Li Zhang
Arterioscler Thromb Vasc Biol. 2023 Oct; 43(10): 1900–1920. Published online 2023 Aug 17. doi: 10.1161/ATVBAHA.123.319281
PMCID:
PMC10521802
AbstractArticlePDF–1.5M
2.
Viral mimetic triggers cerebral arteriopathy in juvenile brain via neutrophil elastase and NETosis
Aditya Rayasam, Amandine Jullienne, Tetyana Chumak, Joel Faustino, Jenny Szu, Mary Hamer, C Joakim Ek, Carina Mallard, Andre Obenaus, Zinaida S Vexler
J Cereb Blood Flow Metab. 2021 Dec; 41(12): 3171–3186. Published online 2021 Jul 22. doi: 10.1177/0271678X211032737
PMCID:
PMC8669290
AbstractArticlePDF–3.0M
3.
Neutrophil-Derived Proteases Contribute to the Pathogenesis of Early Diabetic Retinopathy
Emma M. Lessieur, Haitao Liu, Aicha Saadane, Yunpeng Du, Jie Tang, Jianying Kiser, Timothy S. Kern
Invest Ophthalmol Vis Sci. 2021 Oct; 62(13): 7. Published online 2021 Oct 13. doi: 10.1167/iovs.62.13.7
PMCID:
PMC8525836
AbstractArticlePDF–2.1M
4.
Development of an improved murine model of necrotizing enterocolitis shows the importance of neutrophils in NEC pathogenesis
Michaela Klinke, Deirdre Vincent, Magdalena Trochimiuk, Birgit Appl, Bastian Tiemann, Konrad Reinshagen, Laia Pagerols Raluy, Michael Boettcher
Sci Rep. 2020; 10: 8049. Published online 2020 May 15. doi: 10.1038/s41598-020-65120-y
PMCID:
PMC7229036
AbstractArticlePDF–1.6M
5.
Stromal Cells Covering Omental Fat-Associated Lymphoid Clusters Trigger Formation of Neutrophil Aggregates to Capture Peritoneal Contaminants
Lucy Helen Jackson-Jones, Peter Smith, Jordan Raymond Portman, Marlène Sophie Magalhaes, Katie Jude Mylonas, Matthieu Marie Vermeren, Mark Nixon, Beth Emily Pollot Henderson, Ross Dobie, Sonja Vermeren, Laura Denby, Neil Cowan Henderson, Damian James Mole, Cécile Bénézech
Immunity. 2020 Apr 14; 52(4): 700–715.e6. doi: 10.1016/j.immuni.2020.03.011
PMCID:
PMC7156918
AbstractArticle
6.
Neutrophil elastase plays a non‐redundant role in remodeling the venular basement membrane and neutrophil diapedesis post‐ischemia/reperfusion injury
Mathieu‐Benoit Voisin, Giovanna Leoni, Abigail Woodfin, Laure Loumagne, Nimesh SA Patel, Rosanna Di Paola, Salvatore Cuzzocrea, Christoph Thiemermann, Mauro Perretti, Sussan Nourshargh
J Pathol. 2019 May; 248(1): 88–102. Published online 2019 Mar 22. doi: 10.1002/path.5234
PMCID:
PMC6850085
AbstractArticlePDF–2.7M
7.
Neutrophil Elastase Subverts the Immune Response by Cleaving Toll-Like Receptors and Cytokines in Pneumococcal Pneumonia
Hisanori Domon, Kosuke Nagai, Tomoki Maekawa, Masataka Oda, Daisuke Yonezawa, Wataru Takeda, Takumi Hiyoshi, Hikaru Tamura, Masaya Yamaguchi, Shigetada Kawabata, Yutaka Terao
Front Immunol. 2018; 9: 732. Published online 2018 Apr 25. doi: 10.3389/fimmu.2018.00732
PMCID:
PMC5996908
AbstractArticlePDF–2.1M
8.
Neutrophil Elastase Regulates Emergency Myelopoiesis Preceding Systemic Inflammation in Diet-induced Obesity
Jun-Yuan Huang, Qiong Lin Zhou, Chun-Hong Huang, Ye Song, Andria G. Sharma, Zhangping Liao, Kavin Zhu, Miles W. Massidda, Ryan R. Jamieson, Jun-Yuan Zhang, Daniel G. Tenen, Zhen Y. Jiang
J Biol Chem. 2017 Mar 24; 292(12): 4770–4776. Published online 2017 Feb 15. doi: 10.1074/jbc.C116.758748
PMCID:
PMC5377793
AbstractArticlePDF–1.0M
9.
Neutrophil elastase promotes myofibroblast differentiation in lung fibrosis
Alyssa D. Gregory, Corrine R. Kliment, Heather E. Metz, Kyoung-Hee Kim, Julia Kargl, Brittani A. Agostini, Lauren T. Crum, Elizabeth A. Oczypok, Tim A. Oury, A. McGarry Houghton
J Leukoc Biol. 2015 Aug; 98(2): 143–152. Published online 2015 Mar 5. doi: 10.1189/jlb.3HI1014-493R
PMCID:
PMC4763951
AbstractArticle
10.
Neutrophil elastase mediates acute pathogenesis and is a determinant of long-term behavioral recovery after traumatic injury to the immature brain
Bridgette D Semple, Alpa Trivedi, Kayleen Gimlin, Linda J Noble-Haeusslein
Neurobiol Dis. Author manuscript; available in PMC 2016 Feb 1.
Published in final edited form as: Neurobiol Dis. 2015 Feb; 74: 263–280. Published online 2014 Dec 9. doi: 10.1016/j.nbd.2014.12.003
PMCID:
PMC4323771
AbstractArticlePDF–2.4M
11.
Neutrophils Increase or Reduce Parasite Burden in Trypanosoma cruzi-Infected Macrophages, Depending on Host Strain: Role of Neutrophil Elastase
Tatiana Luna-Gomes, Alessandra A. Filardy, Juliana Dutra B. Rocha, Debora Decote-Ricardo, Isabel Ferreira LaRocque-de-Freitas, Alexandre Morrot, Patrícia T. Bozza, Hugo C. Castro-Faria-Neto, George A. DosReis, Marise P. Nunes, Célio G. Freire-de-Lima
PLoS One. 2014; 9(3): e90582. Published online 2014 Mar 5. doi: 10.1371/journal.pone.0090582
PMCID:
PMC3944110
AbstractArticlePDF–485K
12.
Anti-inflammatory and immunomodulatory properties of α1-antitrypsin without inhibition of elastase
Danny Jonigk, Mariam Al-Omari, Lavinia Maegel, Meike Müller, Nicole Izykowski, Jaewoo Hong, Kwangwon Hong, Soo-Hyun Kim, Martina Dorsch, Ravi Mahadeva, Florian Laenger, Hans Kreipe, Armin Braun, Galit Shahaf, Eli C. Lewis, Tobias Welte, Charles A. Dinarello, Sabina Janciauskiene
Proc Natl Acad Sci U S A. 2013 Sep 10; 110(37): 15007–15012. Published online 2013 Aug 23. doi: 10.1073/pnas.1309648110
PMCID:
PMC3773761
AbstractArticlePDF–345K
13.
Neutrophils mediate insulin resistance in high fat diet fed mice via secreted elastase
Saswata Talukdar, Da Young Oh, Gautam Bandyopadhyay, Dongmei Li, Jianfeng Xu, Joanne McNelis, Min Lu, Pingping Li, Qingyun Yan, Yimin Zhu, Jachelle Ofrecio, Michael Lin, Martin B Brenner, Jerrold M Olefsky
Nat Med. Author manuscript; available in PMC 2013 Mar 1.
Published in final edited form as: Nat Med. 2012 Sep; 18(9): 1407–1412. doi: 10.1038/nm.2885
PMCID:
PMC3491143
ArticlePDF–701K
14.
B–helper neutrophils stimulate immunoglobulin diversification and production in the marginal zone of the spleen
Irene Puga, Montserrat Cols, Carolina M. Barra, Bing He, Linda Cassis, Maurizio Gentile, Laura Comerma, Alejo Chorny, Meimei Shan, Weifeng Xu, Giuliana Magri, Daniel M. Knowles, Wayne Tam, April Chiu, James B Bussel, Sergi Serrano, José Antonio Lorente, Beatriz Bellosillo, Josep Lloreta, Nuria Juanpere, Francesc Alameda, Teresa Baró, Cristina Díaz de Heredia, Núria Torán, Albert Català, Montserrat Torrebadell, Claudia Fortuny, Victoria Cusi, Carmen Carreras, George A. Diaz, J. Magarian Blander, Claire-Michèle Farber, Guido Silvestri, Charlotte Cunningham-Rundles, Michaela Calvillo, Carlo Dufour, Lucia Dora Notarangelo, Vassilios Lougaris, Alessandro Plebani, Jean-Laurent Casanova, Stephanie C. Ganal, Andreas Diefenbach, Juan Ignacio Aróstegui, Manel Juan, Jordi Yagüe, Nizar Mahlaoui, Jean Donadieu, Kang Chen, Andrea Cerutti
Nat Immunol. Author manuscript; available in PMC 2012 Aug 1.
Published in final edited form as: Nat Immunol. 2012 Feb; 13(2): 170–180. Published online 2011 Dec 25. doi: 10.1038/ni.2194
Correction in:
volume 15 on page 205
PMCID:
PMC3262910
AbstractArticlePDF–1.9M
15.
Leishmania inhibitor of serine peptidase prevents TLR4 activation by neutrophil elastase promoting parasite survival in murine macrophages
Marilia S. Faria, Flavia C. G. Reis, Ricardo L. Azevedo-Pereira, Lesley S. Morrison, Jeremy C. Mottram, Ana Paula C. A. Lima
J Immunol. Author manuscript; available in PMC 2011 Jul 1.
Published in final edited form as: J Immunol. 2011 Jan 1; 186(1): 411–422. Published online 2010 Nov 22. doi: 10.4049/jimmunol.1002175
PMCID:
PMC3119636
AbstractArticlePDF–816K
16.
Neutrophil Elastase Contributes to Acute Lung Injury Induced by Bilateral Nephrectomy
Tomoko Ishii, Kent Doi, Koji Okamoto, Mitsuru Imamura, Makoto Dohi, Kazuhiko Yamamoto, Toshiro Fujita, Eisei Noiri
Am J Pathol. 2010 Oct; 177(4): 1665–1673. doi: 10.2353/ajpath.2010.090793
PMCID:
PMC2947264
AbstractArticlePDF–490K
17.
Venular basement membranes contain specific matrix protein low expression regions that act as exit points for emigrating neutrophils
Shijun Wang, Mathieu-Benoit Voisin, Karen Y. Larbi, John Dangerfield, Christoph Scheiermann, Maxine Tran, Patrick H. Maxwell, Lydia Sorokin, Sussan Nourshargh
J Exp Med. 2006 Jun 12; 203(6): 1519–1532. doi: 10.1084/jem.20051210
PMCID:
PMC2118318
AbstractArticlePDF–5.2M
18.
Mice Lacking Neutrophil Elastase Are Resistant to Bleomycin-Induced Pulmonary Fibrosis
Felix Chua, Sarah E. Dunsmore, Peter H. Clingen, Steven E. Mutsaers, Steven D. Shapiro, Anthony W. Segal, Jürgen Roes, Geoffrey J. Laurent
Am J Pathol. 2007 Jan; 170(1): 65–74. doi: 10.2353/ajpath.2007.060352
PMCID:
PMC1762691
AbstractArticlePDF–1.1M
19.
Is neutrophil elastase the missing link between emphysema and fibrosis? Evidence from two mouse models
Monica Lucattelli, Barbara Bartalesi, Eleonora Cavarra, Silvia Fineschi, Benedetta Lunghi, Piero A Martorana, Giuseppe Lungarella
Respir Res. 2005; 6(1): 83. Published online 2005 Jul 26. doi: 10.1186/1465-9921-6-83
PMCID:
PMC1184102
AbstractArticlePDF–1.9M
20.
Degradation of EGFR on lung epithelial cells by neutrophil elastase contributes to the aggravation of pneumococcal pneumonia
Toshihito Isono, Satoru Hirayama, Hisanori Domon, Tomoki Maekawa, Hikaru Tamura, Takumi Hiyoshi, Kridtapat Sirisereephap, Shoji Takenaka, Yuichiro Noiri, Yutaka Terao
J Biol Chem. 2023 Jun; 299(6): 104760. Published online 2023 Apr 27. doi: 10.1016/j.jbc.2023.104760
PMCID:
PMC10220274
AbstractArticlePDF–3.0M

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