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Items: 1 to 20 of 100

1.
Unveiling the methionine cycle: a key metabolic signature and NR4A2 as a methionine-responsive oncogene in esophageal squamous cell carcinoma
Xing Jin, Lei Liu, Dan Liu, Jia Wu, Congcong Wang, Siliang Wang, Fengying Wang, Guanzhen Yu, Xiaoxia Jin, Yu-Wen Xue, Dan Jiang, Yan Ni, Xi Yang, Ming-Song Wang, Zhi-Wei Wang, Yuriy L. Orlov, Wei Jia, Gerry Melino, Ji-Bin Liu, Wen-Lian Chen
Cell Death Differ. 2024 May; 31(5): 558–573. Published online 2024 Apr 3. doi: 10.1038/s41418-024-01285-7
PMCID:
PMC11094133
AbstractArticlePDF–7.3M
2.
Mechanisms of NURR1 Regulation: Consequences for Its Biological Activity and Involvement in Pathology
Ángel Juan García-Yagüe, Antonio Cuadrado
Int J Mol Sci. 2023 Aug; 24(15): 12280. Published online 2023 Jul 31. doi: 10.3390/ijms241512280
PMCID:
PMC10419244
AbstractArticlePDF–1.9M
3.
Recruitment of the CoREST transcription repressor complexes by Nerve Growth factor IB-like receptor (Nurr1/NR4A2) mediates silencing of HIV in microglial cells
Fengchun Ye, David Alvarez-Carbonell, Kien Nguyen, Konstantin Leskov, Yoelvis Garcia-Mesa, Sheetal Sreeram, Saba Valadkhan, Jonathan Karn
PLoS Pathog. 2022 Jul; 18(7): e1010110. Published online 2022 Jul 7. doi: 10.1371/journal.ppat.1010110
PMCID:
PMC9295971
AbstractArticlePDF–6.3M
4.
NURR1 expression regulates retinal pigment epithelial–mesenchymal transition and age-related macular degeneration phenotypes
Pei-Li Yao, Vipul M. Parmar, Mayur Choudhary, Goldis Malek
Proc Natl Acad Sci U S A. 2022 Jul 12; 119(28): e2202256119. Published online 2022 Jul 8. doi: 10.1073/pnas.2202256119
PMCID:
PMC9282432
AbstractArticlePDF–4.3M
5.
The role of NURR1 in metabolic abnormalities of Parkinson’s disease
Murad Al-Nusaif, Yuting Yang, Song Li, Cheng Cheng, Weidong Le
Mol Neurodegener. 2022; 17: 46. Published online 2022 Jun 27. doi: 10.1186/s13024-022-00544-w
PMCID:
PMC9235236
AbstractArticlePDF–1.1M
6.
Nuclear Receptor 4A2 (NR4A2/NURR1) Regulates Autophagy and Chemoresistance in Pancreatic Ductal Adenocarcinoma
Mehrdad Zarei, Rupesh Shrestha, Sneha Johnson, Zuhua Yu, Keshav Karki, Ali Vaziri-Gohar, Jessica Epps, Heng Du, Larry Suva, Mahsa Zarei, Stephen Safe
Cancer Res Commun. 2021 Nov; 1(2): 65–78. Published online 2021 Nov 3. doi: 10.1158/2767-9764.CRC-21-0073
PMCID:
PMC9109828
AbstractArticlePDF–6.5M
7.
NR4A2 expression is not altered in placentas from cases of growth restriction or preeclampsia, but is reduced in hypoxic cytotrophoblast
Natasha de Alwis, Sally Beard, Natalie K. Binder, Natasha Pritchard, Tu’uhevaha J. Kaitu’u-Lino, Susan P. Walker, Owen Stock, Katie M. Groom, Scott Petersen, Amanda Henry, Joanne M. Said, Sean Seeho, Stefan C. Kane, Stephen Tong, Natalie J. Hannan
Sci Rep. 2021; 11: 20670. Published online 2021 Oct 19. doi: 10.1038/s41598-021-00192-y
PMCID:
PMC8526588
AbstractArticlePDF–1.5M
8.
Working memory deficits in schizophrenia are associated with the rs34884856 variant and expression levels of the NR4A2 gene in a sample Mexican population: a case control study
Elizabeth Ruiz-Sánchez, Janet Jiménez-Genchi, Yessica M. Alcántara-Flores, Carlos J. Castañeda-González, Carlos L. Aviña-Cervantes, Petra Yescas, María del Socorro González-Valadez, Nancy Martínez-Rodríguez, Antonio Ríos-Ortiz, Martha González-González, María E. López-Navarro, Patricia Rojas
BMC Psychiatry. 2021; 21: 86. Published online 2021 Feb 9. doi: 10.1186/s12888-021-03081-w
PMCID:
PMC7871565
AbstractArticlePDF–950K
9.
De novo variants of NR4A2 are associated with neurodevelopmental disorder and epilepsy
Sakshi Singh, Aditi Gupta, Michael Zech, Ashley N. Sigafoos, Karl J. Clark, Yasemin Dincer, Matias Wagner, Jennifer B. Humberson, Sarah Green, Koen van Gassen, Tracy Brandt, Rhonda E. Schnur, Francisca Millan, Yue Si, Volker Mall, Juliane Winkelmann, Ralitza H. Gavrilova, Eric W. Klee, Kendra Engleman, Nicole P. Safina, Rachel Slaugh, Emily M. Bryant, Wen-Hann Tan, Jorge Granadillo, Sunita N. Misra, G. Bradley Schaefer, Shelley Towner, Eva H. Brilstra, Bobby P. C. Koeleman
Genet Med. 2020; 22(8): 1413–1417. Published online 2020 May 5. doi: 10.1038/s41436-020-0815-4
PMCID:
PMC7394879
AbstractArticlePDF–489K
10.
Genome-Wide Analysis Identifies NURR1-Controlled Network of New Synapse Formation and Cell Cycle Arrest in Human Neural Stem Cells
Soo Min Kim, Soo Young Cho, Min Woong Kim, Seung Ryul Roh, Hee Sun Shin, Young Ho Suh, Dongho Geum, Myung Ae Lee
Mol Cells. 2020 Jun 30; 43(6): 551–571. Published online 2020 Jun 10. doi: 10.14348/molcells.2020.0071
PMCID:
PMC7332357
AbstractArticlePDF–2.6M
11.
Structural basis of binding of homodimers of the nuclear receptor NR4A2 to selective Nur-responsive DNA elements
Longying Jiang, Shuyan Dai, Jun Li, Xujun Liang, Lingzhi Qu, Xiaojuan Chen, Ming Guo, Zhuchu Chen, Lin Chen, Hudie Wei, Yongheng Chen
J Biol Chem. 2019 Dec 20; 294(51): 19795–19803. Published online 2019 Nov 13. doi: 10.1074/jbc.RA119.010730
PMCID:
PMC6926456
AbstractArticlePDF–1.8M
12.
Heterozygous loss of function of NR4A2 is associated with intellectual deficiency, rolandic epilepsy, and language impairment
Luiza L. P. Ramos, Fabiola P. Monteiro, Leticia P. B. Sampaio, Larissa A. Costa, Mara D. O. Ribeiro, Erika L. Freitas, Joao P. Kitajima, Fernando Kok
Clin Case Rep. 2019 Aug; 7(8): 1582–1584. Published online 2019 Jul 11. doi: 10.1002/ccr3.2260
PMCID:
PMC6693049
AbstractArticlePDF–157K
13.
Heroin Abuse Is Characterized by Discrete Mesolimbic Dopamine and Opioid Abnormalities and Exaggerated Nuclear Receptor-Related 1 Transcriptional Decline with Age
Monika Cs. Horvath, Gabor G. Kovacs, Viktor Kovari, Katalin Majtenyi, Yasmin L. Hurd, Eva Keller
J Neurosci. 2007 Dec 5; 27(49): 13371–13375. doi: 10.1523/JNEUROSCI.2398-07.2007
PMCID:
PMC6673104
AbstractArticlePDF–169K
14.
cDNA microarray analysis identifies NR4A2 as a novel molecule involved in the pathogenesis of Sjögren's syndrome
H. Takahashi, H. Tsuboi, H. Asashima, T. Hirota, Y. Kondo, M. Moriyama, I. Matsumoto, S. Nakamura, T. Sumida
Clin Exp Immunol. 2017 Oct; 190(1): 96–109. Published online 2017 Jul 21. doi: 10.1111/cei.13000
PMCID:
PMC5588759
AbstractArticlePDF–888K
15.
Identification of a Binding Site for Unsaturated Fatty Acids in the Orphan Nuclear Receptor Nurr1
Ian Mitchelle S. de Vera, Pankaj K. Giri, Paola Munoz-Tello, Richard Brust, Jakob Fuhrmann, Edna Matta-Camacho, Jinsai Shang, Sean Campbell, Henry D. Wilson, Juan Granados, William J. Gardner, Jr, Trevor P. Creamer, Laura. A. Solt, Douglas J. Kojetin
ACS Chem Biol. Author manuscript; available in PMC 2017 Jul 15.
Published in final edited form as: ACS Chem Biol. 2016 Jul 15; 11(7): 1795–1799. Published online 2016 Apr 29. doi: 10.1021/acschembio.6b00037
PMCID:
PMC4946999
AbstractArticlePDF–1.2M
16.
Nuclear Receptor Nr4a2 Promotes Alternative Polarization of Macrophages and Confers Protection in Sepsis
Sahil Mahajan, Ankita Saini, Vemika Chandra, Ravikanth Nanduri, Rashi Kalra, Ella Bhagyaraj, Neeraj Khatri, Pawan Gupta
J Biol Chem. 2015 Jul 24; 290(30): 18304–18314. Published online 2015 May 7. doi: 10.1074/jbc.M115.638064
PMCID:
PMC4513091
AbstractArticlePDF–2.0M
17.
The NR4A2 Nuclear Receptor Is Recruited to Novel Nuclear Foci in Response to UV Irradiation and Participates in Nucleotide Excision Repair
Kasturee Jagirdar, Kelvin Yin, Matthew Harrison, Wen Lim, George E. O. Muscat, Richard A. Sturm, Aaron G. Smith
PLoS One. 2013; 8(11): e78075. Published online 2013 Nov 6. doi: 10.1371/journal.pone.0078075
PMCID:
PMC3819332
AbstractArticlePDF–1.8M
18.
Chemoprevention of Skin Cancer with 1,1-Bis (3′-Indolyl)-1-(Aromatic) Methane Analog through Induction of the Orphan Nuclear Receptor, NR4A2 (Nurr1)
Cedar H. A. Boakye, Ravi Doddapaneni, Punit P. Shah, Apurva R. Patel, Chandraiah Godugu, Stephen Safe, Santosh K. Katiyar, Mandip Singh
PLoS One. 2013; 8(8): e69519. Published online 2013 Aug 7. doi: 10.1371/journal.pone.0069519
PMCID:
PMC3737220
AbstractArticlePDF–974K
19.
NR4A2: Effects of an “Orphan” Receptor on Sustained Attention in a Schizophrenic Population
Inés Ancín, José A. Cabranes, Blanca Vázquez-Álvarez, José Luis Santos, Eva Sánchez-Morla, Maaike Alaerts, Jurgen Del-Favero, Ana Barabash
Schizophr Bull. 2013 May; 39(3): 555–563. Published online 2012 Jan 31. doi: 10.1093/schbul/sbr176
PMCID:
PMC3627752
AbstractArticlePDF–761K
20.
Dichotomous roles for the orphan nuclear receptor NURR1 in breast cancer
Shawn Llopis, Brittany Singleton, Tamika Duplessis, Latonya Carrier, Brian Rowan, Christopher Williams
BMC Cancer. 2013; 13: 139. Published online 2013 Mar 21. doi: 10.1186/1471-2407-13-139
PMCID:
PMC3617898
AbstractArticlePDF–6.3M

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