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Select item 88170071.

NPY1R exerts inhibitory action on estradiol-stimulated growth and predicts endocrine sensitivity and better survival in ER-positive breast cancer

Raksha Bhat, Hariprasad Thangavel, Noor Mazin Abdulkareem, Suhas Vasaikar, Carmine De Angelis, Leon Bae, Maria Letizia Cataldo, Sarmistha Nanda, Xiaoyong Fu, Bing Zhang, Rachel Schiff, Meghana V. Trivedi

Sci Rep. 2022; 12: 1972. Published online 2022 Feb 4. doi: 10.1038/s41598-022-05949-7

PMCID:: PMC8817007

Abstract Article PDF–5.9M

Select item 59207362.

Structural basis of ligand binding modes at the neuropeptide Y Y₁ receptor

Zhenlin Yang, Shuo Han, Max Keller, Anette Kaiser, Brian J. Bender, Mathias Bosse, Kerstin Burkert, Lisa M. Kögler, David Wifling, Guenther Bernhardt, Nicole Plank, Timo Littmann, Peter Schmidt, Cuiying Yi, Beibei Li, Sheng Ye, Rongguang Zhang, Bo Xu, Dan Larhammar, Raymond C. Stevens, Daniel Huster, Jens Meiler, Qiang Zhao, Annette G. Beck-Sickinger, Armin Buschauer, Beili Wu

Nature. Author manuscript; available in PMC 2018 Oct 18.

Published in final edited form as: Nature. 2018 Apr; 556(7702): 520–524. Published online 2018 Apr 18. doi: 10.1038/s41586-018-0046-x

PMCID:: PMC5920736

Abstract Article PDF–1.7M

Select item 27926363.

Neuropeptide Y₁ receptor NPY1R: Discovery of naturally occurring human genetic variants governing gene expression in cella as well as pleiotropic effects on autonomic activity and blood pressure in vivo

Lei Wang, Fangwen Rao, Kuixing Zhang, Manjula Mahata, Juan L. Rodriguez-Flores, Maple M. Fung, Jill Waalen, Myles G. Cockburn, Bruce A. Hamilton, Sushil K. Mahata, Daniel T. O'Connor.

J Am Coll Cardiol. Author manuscript; available in PMC 2010 Sep 1.

Published in final edited form as: J Am Coll Cardiol. 2009 Sep 1; 54(10): 944–954. doi: 10.1016/j.jacc.2009.05.035

Correction in:: volume 54 on page 1482

PMCID:: PMC2792636

Abstract Article PDF–1.4M

Select item 26622614.

The Third Intracellular Loop Stabilizes the Inactive State of the Neuropeptide Y1 Receptor

Melissa J. S. Chee, Karin Mörl, Diana Lindner, Nicole Merten, Gerald W. Zamponi, Peter E. Light, Annette G. Beck-Sickinger, William F. Colmers

J Biol Chem. 2008 Nov 28; 283(48): 33337–33346. doi: 10.1074/jbc.M804671200

PMCID:: PMC2662261

Abstract Article PDF–552K

Select item 4110385.

A case of autism with an interstitial deletion on 4q leading to hemizygosity for genes encoding for glutamine and glycine neurotransmitter receptor sub-units (AMPA 2, GLRA3, GLRB) and neuropeptide receptors NPY1R, NPY5R

Subhadra Ramanathan, Abigail Woodroffe, Pamela L Flodman, Lee Z Mays, Mona Hanouni, Charlotte B Modahl, Robin Steinberg-Epstein, Maureen E Bocian, M Anne Spence, Moyra Smith

BMC Med Genet. 2004; 5: 10. Published online 2004 Apr 16. doi: 10.1186/1471-2350-5-10

PMCID:: PMC411038

Abstract Article PDF–289K

Select item 88611196.

Expression of hypoxia inducible factor–dependent neuropeptide Y receptors Y1 and Y5 sensitizes hypoxic cells to NPY stimulation

Philip J. Medeiros, Sydney A. Pascetta, Sarah M. Kirsh, Baraa K. Al-Khazraji, James Uniacke

J Biol Chem. 2022 Mar; 298(3): 101645. Published online 2022 Jan 27. doi: 10.1016/j.jbc.2022.101645

PMCID:: PMC8861119

Abstract Article PDF–2.7M

Select item 88440757.

Structural basis of neuropeptide Y signaling through Y1 receptor

Chaehee Park, Jinuk Kim, Seung-Bum Ko, Yeol Kyo Choi, Hyeongseop Jeong, Hyeonuk Woo, Hyunook Kang, Injin Bang, Sang Ah Kim, Tae-Young Yoon, Chaok Seok, Wonpil Im, Hee-Jung Choi

Nat Commun. 2022; 13: 853. Published online 2022 Feb 14. doi: 10.1038/s41467-022-28510-6

Correction in:: Nat Commun. 2022; 13: 1126.

PMCID:: PMC8844075

Abstract Article PDF–2.8M

Select item 54398878.

Expression of Neuropeptide Y, Substance P, and Their Receptors in the Right Atrium of Diabetic Patients

Asma Ejaz, Frank W. LoGerfo, Kamal Khabbaz, Leena Pradhan

Clin Transl Sci. 2011 Oct; 4(5): 346–350. Published online 2011 Oct 26. doi: 10.1111/j.1752-8062.2011.00318.x

PMCID:: PMC5439887

Abstract Article PDF–39M

Select item 14246859.

Genome Scan for Loci Predisposing to Anxiety Disorders Using a Novel Multivariate Approach: Strong Evidence for a Chromosome 4 Risk Locus

Belhassen Kaabi, Joel Gelernter, Scott W. Woods, Andrew Goddard, Grier P. Page, Robert C. Elston

Am J Hum Genet. 2006 Apr; 78(4): 543–553. Published online 2006 Jan 26. doi: 10.1086/501072

PMCID:: PMC1424685

Abstract Article PDF–223K

Select item 898644110.

Integrative Analysis of Exosomal miR-452 and miR-4713 Downregulating NPY1R for the Prevention of Childhood Obesity

Xiaoyan Feng, Ye Ding, Min Zhou, Na Song, Yanhong Ding

Dis Markers. 2022; 2022: 2843353. Published online 2022 Mar 30. doi: 10.1155/2022/2843353

PMCID:: PMC8986441

Abstract Article PDF–1.3M

Select item 645213111.

A Dysregulation in CES1, APOE and Other Lipid Metabolism-Related Genes Is Associated to Cardiovascular Risk Factors Linked to Obesity

M. Pilar Marrades, Pedro González-Muniesa, J. Alfredo Martínez, María J. Moreno-Aliaga

Obes Facts. 2010 Oct; 3(5): 312–318. Published online 2010 Oct 15. doi: 10.1159/000321451

PMCID:: PMC6452131

Abstract Article PDF–350K

Select item 379387512.

Fluorescence correlation spectroscopy, combined with bimolecular fluorescence complementation, reveals the effects of β-arrestin complexes and endocytic targeting on the membrane mobility of neuropeptide Y receptors

Laura E. Kilpatrick, Stephen J. Briddon, Nicholas D. Holliday

Biochim Biophys Acta. 2012 Jun; 1823(6): 1068–1081. doi: 10.1016/j.bbamcr.2012.03.002

PMCID:: PMC3793875

Abstract Article

Select item 274087013.

Variants in Neuropeptide Y Receptor 1 and 5 Are Associated with Nutrient-Specific Food Intake and Are Under Recent Selection in Europeans

Clara C. Elbers, Carolien G. F. de Kovel, Yvonne T. van der Schouw, Juliaan R. Meijboom, Florianne Bauer, Diederick E. Grobbee, Gosia Trynka, Jana V. van Vliet-Ostaptchouk, Cisca Wijmenga, N. Charlotte Onland-Moret

PLoS One. 2009; 4(9): e7070. Published online 2009 Sep 17. doi: 10.1371/journal.pone.0007070

PMCID:: PMC2740870

Abstract Article PDF–558K

Select item 157326714.

Neuropeptide Y, Y₁, Y₂ and Y₄ receptors mediate Y agonist responses in isolated human colon mucosa

Helen M Cox, Iain R Tough

Br J Pharmacol. 2002 Mar; 135(6): 1505–1512. doi: 10.1038/sj.bjp.0704604

PMCID:: PMC1573267

Abstract Article PDF–225K

Select item 40210415.

Cloned human neuropeptide Y receptor couples to two different second messenger systems.

H Herzog, Y J Hort, H J Ball, G Hayes, J Shine, L A Selbie

Proc Natl Acad Sci U S A. 1992 Jul 1; 89(13): 5794–5798. doi: 10.1073/pnas.89.13.5794

PMCID:: PMC402104

Summary Page Browse PDF–1.0M

Select item 748797516.

Further evidence for the association of GAL, GALR1 and NPY1R variants with opioid dependence

Matthew Randesi, Orna Levran, Wim van den Brink, Peter Blanken, Jan M van Ree, Jurg Ott, Mary J Kreek

Pharmacogenomics. 2020 Aug; 21(13): 903–917. Published online 2020 Aug 6. doi: 10.2217/pgs-2020-0045

PMCID:: PMC7487975

Abstract Article PDF–704K

Select item 265044117.

Neuropeptide Y Receptor Genes Are Associated with Alcohol Dependence, Alcohol Withdrawal Phenotypes and Cocaine Dependence

Leah Wetherill, Marc A. Schuckit, Victor Hesselbrock, Xiaoling Xuei, Tiebing Liang, Danielle M. Dick, John Kramer, John I. Nurnberger, Jr., Jay A. Tischfield, Bernice Porjesz, Howard J. Edenberg, Tatiana Foroud

Alcohol Clin Exp Res. Author manuscript; available in PMC 2009 Dec 1.

Published in final edited form as: Alcohol Clin Exp Res. 2008 Dec; 32(12): 2031–2040. Published online 2008 Sep 25. doi: 10.1111/j.1530-0277.2008.00790.x

PMCID:: PMC2650441

Abstract Article PDF–398K

Select item 412805118.

NPY/Y₁ receptor-mediated vasoconstrictory and proliferative effects in pulmonary hypertension

S Crnkovic, B Egemnazarov, P Jain, U Seay, N Gattinger, L M Marsh, Z Bálint, G Kovacs, B Ghanim, W Klepetko, R T Schermuly, N Weissmann, A Olschewski, G Kwapiszewska

Br J Pharmacol. 2014 Aug; 171(16): 3895–3907. Published online 2014 Jul 25. doi: 10.1111/bph.12751

PMCID:: PMC4128051

Abstract Article PDF–1.6M

Select item 286831219.

NOVEL GENETIC VARIANTS CONTRIBUTING TO LEFT VENTRICULAR HYPERTROPHY: THE HYPERGEN STUDY: Genetic variants for LV hypertrophy

Donna K. Arnett, Richard B. Devereux, DC Rao, Na Li, Weihong Tang, Rachel Kraemer, Steven A. Claas, Joanlise M. Leon, Ulrich Broeckel

J Hypertens. Author manuscript; available in PMC 2010 Aug 1.

Published in final edited form as: J Hypertens. 2009 Aug; 27(8): 1585–1593. doi: 10.1097/HJH.0b013e32832be612

PMCID:: PMC2868312

Abstract Article PDF–629K

Select item 288055820.

Use of Genome-Wide Expression Data to Mine the “Gray Zone” of GWA Studies Leads to Novel Candidate Obesity Genes

Jussi Naukkarinen, Ida Surakka, Kirsi H. Pietiläinen, Aila Rissanen, Veikko Salomaa, Samuli Ripatti, Hannele Yki-Järvinen, Cornelia M. van Duijn, H.-Erich Wichmann, Jaakko Kaprio, Marja-Riitta Taskinen, Leena Peltonen, ENGAGE Consortium

PLoS Genet. 2010 Jun; 6(6): e1000976. Published online 2010 Jun 3. doi: 10.1371/journal.pgen.1000976

PMCID:: PMC2880558

Abstract Article PDF–216K

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PMC Links for Gene (Select 4886) (31)
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RecName: Full=Neuropeptide Y receptor type 1; Short=NPY1-R
RecName: Full=Neuropeptide Y receptor type 1; Short=NPY1-R
gi|128997|sp|P25929.1|NPY1R_HUMAN

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