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Select item 99390521.

Delineation of the clinical profile of CNOT2 haploinsufficiency and overview of the IDNADFS phenotype

Marcello Niceta, Simone Pizzi, Francesca Inzana, Angela Peron, Somayeh Bakhtiari, Mathilde Nizon, Jonathan Levy, Cecilia Mancini, Benjamin Cogné, Francesca Clementina Radio, Emanuele Agolini, Dario Cocciadiferro, Antonio Novelli, Mustafa A. Salih, Maria Paola Recalcati, Rosangela Arancio, Marianne Besnard, Anne‐Claude Tabet, Michael C. Kruer, Manuela Priolo, Bruno Dallapiccola, Marco Tartaglia

Clin Genet. 2023 Feb; 103(2): 156–166. Published online 2022 Nov 24. doi: 10.1111/cge.14247

PMCID:: PMC9939052

Abstract Article PDF–2.4M

Select item 69847792.

CCR4-NOT transcription complex subunit 2 regulates TRAIL sensitivity in non-small-cell lung cancer cells via the STAT3 pathway

Eun-Ok Kim, Shi-Eun Kang, Minji Choi, Ki-Jong Rhee, Miyong Yun

Int J Mol Med. 2020 Feb; 45(2): 324–332. Published online 2019 Dec 12. doi: 10.3892/ijmm.2019.4425

PMCID:: PMC6984779

Abstract Article PDF–1.1M

Select item 55422463.

CNOT2 promotes degradation of p62/SQSTM1 as a negative regulator in ATG5 dependent autophagy

Kwon Jeong, Hee Young Kwon, Myoung Seok Jeong, Eun Jung Sohn, Sung-Hoon Kim

Oncotarget. 2017 Jul 11; 8(28): 46034–46046. Published online 2017 May 8. doi: 10.18632/oncotarget.17682

Correction in:: Oncotarget. 2019 Sep 17; 10(53): 5571.

PMCID:: PMC5542246

Abstract Article PDF–4.9M

Select item 85336954.

Inhibition of CNOT2 Induces Apoptosis via MID1IP1 in Colorectal Cancer Cells by Activating p53

Ji Hoon Jung, Duckgue Lee, Hyun Min Ko, Hyeung-Jin Jang

Biomolecules. 2021 Oct; 11(10): 1492. Published online 2021 Oct 10. doi: 10.3390/biom11101492

PMCID:: PMC8533695

Abstract Article PDF–1.4M

Select item 54712375.

The CCR4-NOT complex contributes to repression of Major Histocompatibility Complex class II transcription

Alfonso Rodríguez-Gil, Olesja Ritter, Vera V. Saul, Jochen Wilhelm, Chen-Yuan Yang, Rudolf Grosschedl, Yumiko Imai, Keiji Kuba, Michael Kracht, M. Lienhard Schmitz

Sci Rep. 2017; 7: 3547. Published online 2017 Jun 14. doi: 10.1038/s41598-017-03708-7

PMCID:: PMC5471237

Abstract Article PDF–5.3M

Select item 15594716.

Involvement of the SMRT/NCoR–HDAC3 complex in transcriptional repression by the CNOT2 subunit of the human Ccr4–Not complex

Sandrine Jayne, Carin G. M. Zwartjes, Frederik M. A. Van Schaik, H. Th. Marc Timmers

Biochem J. 2006 Sep 15; 398(Pt 3): 461–467. Prepublished online 2006 May 19. Published online 2006 Aug 29. doi: 10.1042/BJ20060406

PMCID:: PMC1559471

Abstract Article PDF–425K

Select item 37877177.

Cnot1, Cnot2, and Cnot3 Maintain Mouse and Human ESC Identity and Inhibit Extraembryonic Differentiation

Xiaofeng Zheng, Raluca Dumitru, Brad L. Lackford, Johannes M. Freudenberg, Ajeet P. Singh, Trevor K. Archer, Raja Jothi, Guang Hu

Stem Cells. Author manuscript; available in PMC 2013 Oct 1.

Published in final edited form as: Stem Cells. 2012 May; 30(5): 910–922. doi: 10.1002/stem.1070

PMCID:: PMC3787717

Abstract Article PDF–3.4M

Select item 63628128.

A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4–NOT complex

Csilla Keskeny, Tobias Raisch, Annamaria Sgromo, Cátia Igreja, Dipankar Bhandari, Oliver Weichenrieder, Elisa Izaurralde

Genes Dev. 2019 Feb 1; 33(3-4): 236–252. doi: 10.1101/gad.320952.118

PMCID:: PMC6362812

Abstract Article PDF–2.5M

Select item 15009869.

Human Ccr4-Not complex is a ligand-dependent repressor of nuclear receptor-mediated transcription

G Sebastiaan Winkler, Klaas W Mulder, Vivian J Bardwell, Eric Kalkhoven, H Th Marc Timmers

EMBO J. 2006 Jul 12; 25(13): 3089–3099. Published online 2006 Jun 15. doi: 10.1038/sj.emboj.7601194

PMCID:: PMC1500986

Abstract Article PDF–583K

Select item 10256010.

Isolation and characterization of human orthologs of yeast CCR4–NOT complex subunits

Thomas K. Albert, Marc Lemaire, Nynke L. van Berkum, Reiner Gentz, Martine A. Collart, H. Th. Marc Timmers

Nucleic Acids Res. 2000 Feb 1; 28(3): 809–817. doi: 10.1093/nar/28.3.809

PMCID:: PMC102560

Abstract Article PDF–445K

Select item 663933111.

Reconstitution of recombinant human CCR4-NOT reveals molecular insights into regulated deadenylation

Tobias Raisch, Chung-Te Chang, Yevgen Levdansky, Sowndarya Muthukumar, Stefan Raunser, Eugene Valkov

Nat Commun. 2019; 10: 3173. Published online 2019 Jul 18. doi: 10.1038/s41467-019-11094-z

PMCID:: PMC6639331

Abstract Article PDF–3.8M

Select item 195148912.

Depletion of Mammalian CCR4b Deadenylase Triggers Elevation of the p27^Kip1 mRNA Level and Impairs Cell Growth

Masahiro Morita, Toru Suzuki, Takahisa Nakamura, Kazumasa Yokoyama, Takashi Miyasaka, Tadashi Yamamoto

Mol Cell Biol. 2007 Jul; 27(13): 4980–4990. Published online 2007 Apr 23. doi: 10.1128/MCB.02304-06

PMCID:: PMC1951489

Abstract Article PDF–1.1M

Select item 866080013.

RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation

Fabian Poetz, Joshua Corbo, Yevgen Levdansky, Alexander Spiegelhalter, Doris Lindner, Vera Magg, Svetlana Lebedeva, Jörg Schweiggert, Johanna Schott, Eugene Valkov, Georg Stoecklin

Nat Commun. 2021; 12: 7175. Published online 2021 Dec 9. doi: 10.1038/s41467-021-27471-6

PMCID:: PMC8660800

Abstract Article PDF–5.3M

Select item 383923414.

Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1

The ALSGEN Consortium

Neurobiol Aging. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: Neurobiol Aging. 2013 Jan; 34(1): 10.1016/j.neurobiolaging.2012.07.017. Published online 2012 Sep 5. doi: 10.1016/j.neurobiolaging.2012.07.017

PMCID:: PMC3839234

Abstract Article PDF–1.3M

Select item 1115897715.

Interaction of antiproliferative protein Tob with the CCR4‐NOT deadenylase complex

Takashi Miyasaka, Masahiro Morita, Kentaro Ito, Toru Suzuki, Hiroyuki Fukuda, Shizu Takeda, Jun‐Ichiro Inoue, Kentaro Semba, Tadashi Yamamoto

Cancer Sci. 2008 Apr; 99(4): 755–761. Published online 2008 Mar 28. doi: 10.1111/j.1349-7006.2008.00746.x

PMCID:: PMC11158977

Abstract Article PDF–210K

Select item 646459316.

DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169

Vijay R. Menon, Varsha Ananthapadmanabhan, Selene Swanson, Siddharth Saini, Fatmata Sesay, Vasily Yakovlev, Laurence Florens, James A. DeCaprio, Michael P. Washburn, Mikhail Dozmorov, Larisa Litovchick

Cell Cycle. 2019; 18(5): 531–551. Published online 2019 Feb 17. doi: 10.1080/15384101.2019.1577525

PMCID:: PMC6464593

Abstract Article PDF–2.8M

Select item 451071117.

RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway

Yasuhiro Murakawa, Michael Hinz, Janina Mothes, Anja Schuetz, Michael Uhl, Emanuel Wyler, Tomoharu Yasuda, Guido Mastrobuoni, Caroline C. Friedel, Lars Dölken, Stefan Kempa, Marc Schmidt-Supprian, Nils Blüthgen, Rolf Backofen, Udo Heinemann, Jana Wolf, Claus Scheidereit, Markus Landthaler

Nat Commun. 2015; 6: 7367. Published online 2015 Jul 14. doi: 10.1038/ncomms8367

PMCID:: PMC4510711

Abstract Article PDF–3.2M

Select item 356134318.

VCP Phosphorylation-Dependent Interaction Partners Prevent Apoptosis in Helicobacter pylori-Infected Gastric Epithelial Cells

Cheng-Chou Yu, Jyh-Chin Yang, Yen-Ching Chang, Jiing-Guang Chuang, Chung-Wu Lin, Ming-Shiang Wu, Lu-Ping Chow

PLoS One. 2013; 8(1): e55724. Published online 2013 Jan 31. doi: 10.1371/journal.pone.0055724

PMCID:: PMC3561343

Abstract Article PDF–1.9M

Select item 636858419.

The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer

Weimei Tang, Weijie Zhou, Li Xiang, Xiaosheng Wu, Pei Zhang, Jing Wang, Guangnan Liu, Wenjing Zhang, Ying Peng, Xiaoting Huang, Jianqun Cai, Yang Bai, Lan Bai, Wei Zhu, Hongxiang Gu, Jing Xiong, Chen Ye, Aimin Li, Side Liu, Jide Wang

Nat Commun. 2019; 10: 663. Published online 2019 Feb 8. doi: 10.1038/s41467-018-08225-3

PMCID:: PMC6368584

Abstract Article PDF–6.8M

Select item 31093420.

Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells

Qing-Hua Zhang, Min Ye, Xin-Yan Wu, Shuang-Xi Ren, Meng Zhao, Chun-Jun Zhao, Gang Fu, Yu Shen, Hui-Yong Fan, Gang Lu, Ming Zhong, Xiang-Ru Xu, Ze-Guang Han, Ji-Wang Zhang, Jiong Tao, Qiu-Hua Huang, Jun Zhou, Geng-Xi Hu, Jian Gu, Sai-Juan Chen, Zhu Chen

Genome Res. 2000 Oct; 10(10): 1546–1560. doi: 10.1101/gr.140200

PMCID:: PMC310934

Abstract Article PDF–1.3M

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PMC Links for Gene (Select 4848) (56)
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CCR4-NOT transcription complex subunit 2 isoform X1 [Homo sapiens]
CCR4-NOT transcription complex subunit 2 isoform X1 [Homo sapiens]
gi|1034579707|ref|XP_016874837.1|

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