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Select item 108384481.

Recent advances of NFATc1 in rheumatoid arthritis-related bone destruction: mechanisms and potential therapeutic targets

Hao Zheng, Yuexuan Liu, Yasi Deng, Yunzhe Li, Shiqi Liu, Yong Yang, Yun Qiu, Bin Li, Wenbing Sheng, Jinzhi Liu, Caiyun Peng, Wei Wang, Huanghe Yu

Mol Med. 2024; 30: 20. Published online 2024 Feb 3. doi: 10.1186/s10020-024-00788-w

PMCID:: PMC10838448

Abstract Article PDF–3.3M

Select item 90186232.

DNA methylation of Nuclear Factor of Activated T Cells 1 mediates the prospective relation between exposure to different traumatic event types and post-traumatic stress disorder

James R. Occean, Agaz H. Wani, Janelle Donglasan, Allison E. Aiello, Sandro Galea, Karestan C. Koenen, Annie Qu, Derek E. Wildman, Monica Uddin

Psychiatry Res. Author manuscript; available in PMC 2023 May 1.

Published in final edited form as: Psychiatry Res. 2022 May; 311: 114510. Published online 2022 Mar 19. doi: 10.1016/j.psychres.2022.114510

PMCID:: PMC9018623

Abstract Article PDF–605K

Select item 84577093.

Genetic and functional analyses detect one pathological NFATC1 mutation in a Chinese tricuspid atresia family.

Bojian Li, Tingting Li, Tian Pu, Chunjie Liu, Sun Chen, Kun Sun, Rang Xu

Mol Genet Genomic Med. 2021 Sep; 9(9): e1771. Published online 2021 Aug 7. doi: 10.1002/mgg3.1771

PMCID:: PMC8457709

Abstract Article PDF–586K

Select item 70771724.

The elevated serum levels of calcineurin and nuclear factor of activated T-cells 1 in children with Kawasaki disease

Yameng Sun, Jingjing Liu, Zhimin Geng, Yijing Tao, Fenglei Zheng, Ying Wang, Songling Fu, Wei Wang, Chunhong Xie, Yiying Zhang, Fangqi Gong

Pediatr Rheumatol Online J. 2020; 18: 23. Published online 2020 Mar 17. doi: 10.1186/s12969-020-0420-8

PMCID:: PMC7077172

Abstract Article PDF–705K

Select item 61439405.

NFATc1 is a tumor suppressor in hepatocellular carcinoma and induces tumor cell apoptosis by activating the FasL‐mediated extrinsic signaling pathway

Sanrong Xu, Penghao Shu, Song Zou, Xiaofeng Shen, Yuanqian Qu, Yong Zhang, Kang Sun, Jin Zhang

Cancer Med. 2018 Sep; 7(9): 4701–4717. Published online 2018 Aug 7. doi: 10.1002/cam4.1716

PMCID:: PMC6143940

Abstract Article PDF–1.5M

Select item 56581446.

Src-family kinases negatively regulate NFAT signaling in resting human T cells

Alan Baer, Winston Colon-Moran, Jinhua Xiang, Jack T. Stapleton, Nirjal Bhattarai

PLoS One. 2017; 12(10): e0187123. Published online 2017 Oct 26. doi: 10.1371/journal.pone.0187123

PMCID:: PMC5658144

Abstract Article PDF–3.5M

Select item 49429857.

The role of nuclear factor of activated T cells during phorbol myristate acetate-induced cardiac differentiation of mesenchymal stem cells

Hyang-Hee Seo, Chang Youn Lee, Jiyun Lee, Soyeon Lim, Eunhyun Choi, Jong-Chul Park, Seahyoung Lee, Ki-Chul Hwang

Stem Cell Res Ther. 2016; 7: 90. Published online 2016 Jul 12. doi: 10.1186/s13287-016-0348-6

PMCID:: PMC4942985

Abstract Article PDF–1.3M

Select item 44561648.

Linkage Analysis in Autoimmune Addison’s Disease: NFATC1 as a Potential Novel Susceptibility Locus

Anna L. Mitchell, Anette Bøe Wolff, Katie MacArthur, Jolanta U. Weaver, Bijay Vaidya, Sophie Bensing on behalf of The Swedish Addison Registry Study Group, Martina M. Erichsen, Rebecca Darlay, Eystein S. Husebye, Heather J. Cordell, Simon H. S. Pearce

PLoS One. 2015; 10(6): e0123550. Published online 2015 Jun 4. doi: 10.1371/journal.pone.0123550

Correction in:: PLoS One. 2015; 10(9): e0138844.

PMCID:: PMC4456164

Abstract Article PDF–439K

Select item 43553569.

Attenuation of microglial activation in a mouse model of Alzheimer’s disease via NFAT inhibition

Lalida Rojanathammanee, Angela M Floden, Gunjan D Manocha, Colin K Combs

J Neuroinflammation. 2015; 12: 42. Published online 2015 Mar 4. doi: 10.1186/s12974-015-0255-2

PMCID:: PMC4355356

Abstract Article PDF–1.6M

Select item 350751910.

Oxytocin-Stimulated NFAT Transcriptional Activation in Human Myometrial Cells

Jason N. A. Pont, Craig A. McArdle, Andrés López Bernal

Mol Endocrinol. 2012 Oct; 26(10): 1743–1756. Published online 2012 Aug 17. doi: 10.1210/me.2012-1057

PMCID:: PMC3507519

Abstract Article

Select item 306243211.

DNA binding sites target nuclear NFATc1 to heterochromatin regions in adult skeletal muscle fibers

Tiansheng Shen, Yewei Liu, Minerva Contreras, Erick O. Hernández-Ochoa, William R. Randall, Martin F. Schneider

Histochem Cell Biol. Author manuscript; available in PMC 2011 Oct 1.

Published in final edited form as: Histochem Cell Biol. 2010 Oct; 134(4): 387–402. Published online 2010 Sep 24. doi: 10.1007/s00418-010-0744-4

PMCID:: PMC3062432

Abstract Article PDF–1.5M

Select item 298154212.

An epigenetic chromatin remodeling role for NFATc1 in transcriptional regulation of growth and survival genes in diffuse large B-cell lymphomas

Lan V. Pham, Archito T. Tamayo, Changping Li, Carlos Bueso-Ramos, Richard J. Ford

Blood. 2010 Nov 11; 116(19): 3899–3906. Prepublished online 2010 Jul 27. doi: 10.1182/blood-2009-12-257378

PMCID:: PMC2981542

Abstract Article

Select item 269782013.

Crystal structure of NFAT bound to the HIV-1 LTR tandem kappaB enhancer element

Darren L. Bates, Kristen K. B. Barthel, Yongqing Wu, Reza Kalhor, James C. Stroud, Michael J. Giffin, Lin Chen

Structure. Author manuscript; available in PMC 2009 Jun 17.

Published in final edited form as: Structure. 2008 May; 16(5): 684–694. doi: 10.1016/j.str.2008.01.020

PMCID:: PMC2697820

Abstract Article PDF–4.5M

Select item 269591614.

Aberrant activation of nuclear factor of activated T cell 2 in lamina propria mononuclear cells in ulcerative colitis

Tsung-Chieh Shih, Sen-Yung Hsieh, Yi-Yueh Hsieh, Tse-Chin Chen, Chien-Yu Yeh, Chun-Jung Lin, Deng-Yn Lin, Cheng-Tang Chiu

World J Gastroenterol. 2008 Mar 21; 14(11): 1759–1767. Published online 2008 Mar 21. doi: 10.3748/wjg.14.1759

PMCID:: PMC2695916

Abstract Article PDF–2.6M

Select item 267198215.

NFAT regulates induction of COX-2 and apoptosis of keratinocytes in response to ultraviolet radiation exposure

R. J. Flockhart, B. L. Diffey, P. M. Farr, J. Lloyd, N. J. Reynolds

FASEB J. 2008 Dec; 22(12): 4218–4227. doi: 10.1096/fj.08-113076

PMCID:: PMC2671982

Abstract Article

Select item 141532616.

Activity- and Calcineurin-independent Nuclear Shuttling of NFATc1, but Not NFATc3, in Adult Skeletal Muscle Fibers

Tiansheng Shen, Yewei Liu, Zoltán Cseresnyés, Arie Hawkins, William R. Randall, Martin F. Schneider

Mol Biol Cell. 2006 Apr; 17(4): 1570–1582. doi: 10.1091/mbc.E05-08-0780

PMCID:: PMC1415326

Abstract Article PDF–822K

Select item 1064343617.

Exosome-targeted delivery of METTL14 regulates NFATc1 m6A methylation levels to correct osteoclast-induced bone resorption

Jin-Gang Yang, Bao Sun, Zheng Wang, Xing Li, Jia-hui Gao, Jia-jun Qian, Jiang Li, Wen-jia Wei, Ping Zhang, Wei Wang

Cell Death Dis. 2023 Nov; 14(11): 738. Published online 2023 Nov 13. doi: 10.1038/s41419-023-06263-4

PMCID:: PMC10643436

Abstract Article PDF–8.2M

Select item 1046507818.

Risk Variants in or Near ZBTB40 AND NFATC1 Increase the Risk of Both IBD and Adverse Bone Health Outcomes Highlighting Common Genetic Underpinnings Across Both Diseases

Kelly C Cushing, Yanhua Chen, Xiaomeng Du, Vincent Chen, Annapurna Kuppa, Peter Higgins, Elizabeth K Speliotes

Inflamm Bowel Dis. 2023 Jun; 29(6): 938–945. Published online 2023 Jan 21. doi: 10.1093/ibd/izac273

PMCID:: PMC10465078

Abstract Article PDF–1.1M

Select item 1022803919.

Human bone marrow-derived mesenchymal stem overexpressing microRNA-124-3p inhibit DLBCL progression by downregulating the NFATc1/cMYC pathway

Xiaoxuan Zhao, Mingxi Xu, Xuemeng Hu, Xiaolei Ding, Xian Zhang, Liye Xu, Li Li, Xiuhua Sun, Jincheng Song

Stem Cell Res Ther. 2023; 14: 148. Published online 2023 May 29. doi: 10.1186/s13287-023-03373-w

PMCID:: PMC10228039

Abstract Article PDF–7.7M

Select item 991424020.

NFATc1 Regulation of Dexamethasone-Induced TGFB2 Expression Is Cell Cycle Dependent in Trabecular Meshwork Cells

Mark S. Filla, Jennifer A. Faralli, Caleigh R. Dunn, Haania Khan, Donna M. Peters

Cells. 2023 Feb; 12(3): 504. Published online 2023 Feb 3. doi: 10.3390/cells12030504

PMCID:: PMC9914240

Abstract Article PDF–46M

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PMC Links for Gene (Select 4772) (138)
PMC
Homo sapiens hydroxysteroid 11-beta dehydrogenase 1 like (HSD11B1L), transcript ...
Homo sapiens hydroxysteroid 11-beta dehydrogenase 1 like (HSD11B1L), transcript variant h, mRNA
gi|1677537326|ref|NM_001267870.2|

Nucleotide
Homo sapiens Rho GTPase activating protein 4 (ARHGAP4), transcript variant 2, mR...
Homo sapiens Rho GTPase activating protein 4 (ARHGAP4), transcript variant 2, mRNA
gi|1677531354|ref|NM_001666.5|

Nucleotide
Homo sapiens ribosomal protein L36 (RPL36), transcript variant 1, mRNA
Homo sapiens ribosomal protein L36 (RPL36), transcript variant 1, mRNA
gi|1519242556|ref|NM_033643.3|

Nucleotide
Homo sapiens jumonji domain containing 2B, mRNA (cDNA clone IMAGE:30389696), com...
Homo sapiens jumonji domain containing 2B, mRNA (cDNA clone IMAGE:30389696), complete cds
gi|39645660|gb|BC063889.1|

Nucleotide

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