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Select item 110433761.

ATF3 characterizes aggressive drug-tolerant persister cells in HGSOC

Kathrin Böpple, Yaara Oren, Whitney S. Henry, Meng Dong, Sandra Weller, Julia Thiel, Markus Kleih, Andrea Gaißler, Damaris Zipperer, Hans-Georg Kopp, Yael Aylon, Moshe Oren, Frank Essmann, Chunguang Liang, Walter E. Aulitzky

Cell Death Dis. 2024 Apr; 15(4): 290. Published online 2024 Apr 24. doi: 10.1038/s41419-024-06674-x

PMCID:: PMC11043376

Abstract Article PDF–3.4M

Select item 108049302.

Activating transcription factor 3 is a new biomarker correlation with renal clear cell carcinoma progression

Zhicong Yang, Yongwang Hou, Jingqi Li, Dandan Xu, Zhichao Yang, Xinsheng Wang

Int J Immunopathol Pharmacol. 2024 Jan-Dec; 38: 03946320241227320. Published online 2024 Jan 22. doi: 10.1177/03946320241227320

PMCID:: PMC10804930

Abstract Article PDF–2.0M

Select item 105760323.

Identification of ATF3 as a novel protective signature of quiescent colorectal tumor cells

Xi Lu, Lei Zhong, Emma Lindell, Margus Veanes, Jing Guo, Miao Zhao, Maede Salehi, Fredrik J. Swartling, Xingqi Chen, Tobias Sjöblom, Xiaonan Zhang

Cell Death Dis. 2023 Oct; 14(10): 676. Published online 2023 Oct 13. doi: 10.1038/s41419-023-06204-1

PMCID:: PMC10576032

Abstract Article PDF–4.9M

Select item 100761834.

Activating transcription factor 3, glucolipid metabolism, and metabolic diseases

Shuwei Hu, Xiaojie Zhao, Rui Li, Chencheng Hu, Huijuan Wu, Jing Li, Yanqiao Zhang, Yanyong Xu

J Mol Cell Biol. 2022 Oct; 14(10): mjac067. Published online 2022 Dec 6. doi: 10.1093/jmcb/mjac067

PMCID:: PMC10076183

Abstract Article PDF–924K

Select item 98111575.

ATF3 Reprograms the Bone Marrow Niche in Response to Early Breast Cancer Transformation

Milena Perrone, Claudia Chiodoni, Mara Lecchi, Laura Botti, Barbara Bassani, Annamaria Piva, Elena Jachetti, Matteo Milani, Daniele Lecis, Elda Tagliabue, Paolo Verderio, Sabina Sangaletti, Mario P. Colombo

Cancer Res. 2023 Jan 4; 83(1): 117–129. Published online 2022 Nov 1. doi: 10.1158/0008-5472.CAN-22-0651

PMCID:: PMC9811157

Abstract Article PDF–39M

Select item 88063246.

Activating transcription factor 3 (ATF3) regulates cell growth, apoptosis, invasion and collagen synthesis in keloid fibroblast through transforming growth factor beta (TGF-beta)/SMAD signaling pathway

Xue-Ming Wang, Xiu-Mei Liu, Yuting Wang, Zhen-Yu Chen

Bioengineered. 2021; 12(1): 117–126. Published online 2020 Dec 23. doi: 10.1080/21655979.2020.1860491

PMCID:: PMC8806324

Abstract Article PDF–4.2M

Select item 87566757.

ATF3 Modulates the Resistance of Breast Cancer Cells to Tamoxifen through an N⁶‑Methyladenosine-Based Epitranscriptomic Mechanism

Xiaochuan Liu, Jun Yuan, Xudong Zhang, Lin Li, Xiaoxia Dai, Qi Chen, Yinsheng Wang

Chem Res Toxicol. Author manuscript; available in PMC 2022 Jul 19.

Published in final edited form as: Chem Res Toxicol. 2021 Jul 19; 34(7): 1814–1821. Published online 2021 Jul 2. doi: 10.1021/acs.chemrestox.1c00206

PMCID:: PMC8756675

Abstract Article PDF–1.2M

Select item 86397508.

Decreased expression of ATF3, orchestrated by β-catenin/TCF3, miR-17-5p and HOXA11-AS, promoted gastric cancer progression via increased β-catenin and CEMIP

Guohua Xie, Ping Dong, Hui Chen, Ling Xu, Yi Liu, Yanhui Ma, Yingxia Zheng, Junyao Yang, Yunlan Zhou, Lei Chen, Lisong Shen

Exp Mol Med. 2021 Nov; 53(11): 1706–1722. Published online 2021 Nov 2. doi: 10.1038/s12276-021-00694-9

PMCID:: PMC8639750

Abstract Article PDF–7.9M

Select item 84910989.

ATF3 promotes the serine synthesis pathway and tumor growth under dietary serine restriction

Xingyao Li, Daniel Gracilla, Lun Cai, Mingyi Zhang, Xiaolin Yu, Xiaoguang Chen, Junran Zhang, Xiaochun Long, Han-Fei Ding, Chunhong Yan

Cell Rep. Author manuscript; available in PMC 2021 Oct 5.

Published in final edited form as: Cell Rep. 2021 Sep 21; 36(12): 109706. doi: 10.1016/j.celrep.2021.109706

PMCID:: PMC8491098

Abstract Article PDF–2.2M

Select item 846353410.

ATF3 contributes to brucine-triggered glioma cell ferroptosis via promotion of hydrogen peroxide and iron

Shan Lu, Xuan-zhong Wang, Chuan He, Lei Wang, Shi-peng Liang, Chong-cheng Wang, Chen Li, Tian-fei Luo, Chun-sheng Feng, Zhen-chuan Wang, Guang-fan Chi, Peng-fei Ge

Acta Pharmacol Sin. 2021 Oct; 42(10): 1690–1702. Published online 2021 Jun 10. doi: 10.1038/s41401-021-00700-w

PMCID:: PMC8463534

Abstract Article PDF–7.4M

Select item 845214911.

ATF3 COORDINATES SERINE AND NUCLEOTIDE METABOLISM TO DRIVE CELL CYCLE PROGRESSION IN ACUTE MYELOID LEUKEMIA

Daniela Di Marcantonio, Esteban Martinez, Joice S. Kanefsky, Jacklyn M. Huhn, Rashid Gabbasov, Anushk Gupta, John J. Krais, Suraj Peri, YinFei Tan, Tomasz Skorski, Adrienne Dorrance, Ramiro Garzon, Aaron R. Goldman, Hsin-Yao Tang, Neil Johnson, Stephen M. Sykes

Mol Cell. Author manuscript; available in PMC 2022 Jul 1.

Published in final edited form as: Mol Cell. 2021 Jul 1; 81(13): 2752–2764.e6. Published online 2021 Jun 2. doi: 10.1016/j.molcel.2021.05.008

PMCID:: PMC8452149

Abstract Article PDF–2.6M

Select item 831728712.

Research on the correlation between activating transcription factor 3 expression in the human coronary artery and atherosclerotic plaque stability

J. Peng, C. Y. Le, B. Xia, J. W. Wang, J. J. Liu, Z. Li, Q. J. Zhang, Q. Zhang, J. Wang, C. W. Wan

BMC Cardiovasc Disord. 2021; 21: 356. Published online 2021 Jul 28. doi: 10.1186/s12872-021-02161-9

PMCID:: PMC8317287

Abstract Article PDF–5.0M

Select item 818608213.

Induction of ferroptosis by ATF3 elevation alleviates cisplatin resistance in gastric cancer by restraining Nrf2/Keap1/xCT signaling

Dazhi Fu, Chunxiao Wang, Lei Yu, Rui Yu

Cell Mol Biol Lett. 2021; 26: 26. Published online 2021 Jun 7. doi: 10.1186/s11658-021-00271-y

PMCID:: PMC8186082

Abstract Article PDF–1.5M

Select item 809196714.

ATF-3 expression inhibits melanoma growth by downregulating ERK and AKT pathways

Tingjian Zu, Diana Wang, Shuyun Xu, Catherine A. A. Lee, Ellen Zhen, Charles H. Yoon, Phammela Abarzua, Shuangshuang Wang, Natasha Y. Frank, Xunwei Wu, Christine G. Lian, George F. Murphy

Lab Invest. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: Lab Invest. 2021 May; 101(5): 636–647. Published online 2020 Dec 9. doi: 10.1038/s41374-020-00516-y

PMCID:: PMC8091967

Abstract Article PDF–2.0M

Select item 804190215.

ATF3 deficiency impairs the proliferative–secretory phase transition and decidualization in RIF patients

Zhilong Wang, Yang Liu, Jingyu Liu, Na Kong, Yue Jiang, Ruiwei Jiang, Xin Zhen, Jidong Zhou, Chaojun Li, Haixiang Sun, Guijun Yan

Cell Death Dis. 2021 Apr; 12(4): 387. Published online 2021 Apr 12. doi: 10.1038/s41419-021-03679-8

PMCID:: PMC8041902

Abstract Article PDF–4.9M

Select item 796333516.

ATF3 drives senescence by reconstructing accessible chromatin profiles

Chao Zhang, Xuebin Zhang, Li Huang, Yiting Guan, Xiaoke Huang, Xiao‐Li Tian, Lijun Zhang, Wei Tao

Aging Cell. 2021 Mar; 20(3): e13315. Published online 2021 Feb 4. doi: 10.1111/acel.13315

PMCID:: PMC7963335

Abstract Article PDF–2.8M

Select item 722627917.

Epstein‐Barr virus‐positive gastric cancer involves enhancer activation through activating transcription factor 3

Yuta Asakawa, Atsushi Okabe, Masaki Fukuyo, Wenzhe Li, Eriko Ikeda, Yasunobu Mano, Sayaka Funata, Hiroe Namba, Takahiro Fujii, Kazuko Kita, Keisuke Matsusaka, Atsushi Kaneda

Cancer Sci. 2020 May; 111(5): 1818–1828. Published online 2020 Mar 20. doi: 10.1111/cas.14370

PMCID:: PMC7226279

Abstract Article PDF–1.5M

Select item 698119818.

Defective transcription of ATF3 responsive genes, a marker for Cockayne Syndrome

Alexey Epanchintsev, Marc-Alexander Rauschendorf, Federico Costanzo, Nadege Calmels, Cathy Obringer, Alain Sarasin, Frederic Coin, Vincent Laugel, Jean-Marc Egly

Sci Rep. 2020; 10: 1105. Published online 2020 Jan 24. doi: 10.1038/s41598-020-57999-4

PMCID:: PMC6981198

Abstract Article PDF–1.7M

Select item 684879319.

Mitochondrial oxidative stress-induced transcript variants of ATF3 mediate lipotoxic brain microvascular injury

Tun Nyunt, Monica Britton, Kwanjeera Wanichthanarak, Madhu Budamagunta, John C. Voss, Dennis W. Wilson, John C. Rutledge, Hnin H. Aung

Free Radic Biol Med. Author manuscript; available in PMC 2020 Nov 1.

Published in final edited form as: Free Radic Biol Med. 2019 Nov 1; 143: 25–46. Published online 2019 Jul 26. doi: 10.1016/j.freeradbiomed.2019.07.024

PMCID:: PMC6848793

Abstract Article PDF–4.2M

Select item 632320420.

Overexpression of activating transcription factor 3 exerts suppressive effects in HepG2 cells

Xiaoyan Li, Shengbing Zang, Haili Cheng, Jiasi Li, Aimin Huang

Mol Med Rep. 2019 Feb; 19(2): 869–876. Published online 2018 Nov 29. doi: 10.3892/mmr.2018.9707

PMCID:: PMC6323204

Abstract Article PDF–1.7M

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