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Select item 109071641.

Bulky hydrophobic side chains in the β1-sandwich of microsomal triglyceride transfer protein are critical for the transfer of both triglycerides and phospholipids

Narasimha Anaganti, Swati Valmiki, Rosario Recacha, Shahidul Islam, Steven Farber, Lloyd Ruddock, M. Mahmood Hussain

J Biol Chem. 2024 Mar; 300(3): 105726. Published online 2024 Feb 5. doi: 10.1016/j.jbc.2024.105726

PMCID:: PMC10907164

Abstract Article PDF–5.6M

Select item 105078312.

Association between MTTP genotype (-493G/T) polymorphism and hepatic steatosis in hepatitis C: a systematic review and meta-analysis

Xiaoxia Wang, Yu Cao, Jia Guo, Dezhao Li, Haitao Zhang, Qingkun Song, Jun Lu

Lipids Health Dis. 2023; 22: 154. Published online 2023 Sep 19. doi: 10.1186/s12944-023-01916-x

PMCID:: PMC10507831

Abstract Article PDF–2.3M

Select item 94243423.

Effect of MTTP -493G/T, I128T, Q95H and Q244E polymorphisms on hepatic steatosis in patients with chronic hepatitis

Thamiris Vaz Gago Prata, Caroline Manchiero, Bianca Peixoto Dantas, Arielle Karen da Silva Nunes, Fátima Mitiko Tengan, Mariana Cavalheiro Magri

Clinics (Sao Paulo) 2022 Jan-Dec; 77: 100094. Published online 2022 Aug 23. doi: 10.1016/j.clinsp.2022.100094

PMCID:: PMC9424342

Abstract Article PDF–385K

Select item 85695534.

An improved assay to measure the phospholipid transfer activity of microsomal triglyceride transport protein

Narasimha Anaganti, Sujith Rajan, M. Mahmood Hussain

J Lipid Res. 2021; 62: 100136. Published online 2021 Oct 18. doi: 10.1016/j.jlr.2021.100136

PMCID:: PMC8569553

Abstract Article PDF–1.8M

Select item 83046455.

17β-Estradiol-Induced Conformational Changes of Human Microsomal Triglyceride Transfer Protein: A Computational Molecular Modelling Study

Yong-Xiao Yang, Peng Li, Pan Wang, Bao-Ting Zhu

Cells. 2021 Jul; 10(7): 1566. Published online 2021 Jun 22. doi: 10.3390/cells10071566

PMCID:: PMC8304645

Abstract Article PDF–5.1M

Select item 79579826.

A novel p.Gly417Valfs*12 mutation in the MTTP gene causing abetalipoproteinemia: Presentation of the first patient in Mexico and analysis of the previously reported cases

Perla Graciela Rodríguez Gutiérrez, Juan Ramón González García, Yolanda Alicia Castillo De León, Juan Rafael Zárate Guerrero, María Teresa Magaña Torres

J Clin Lab Anal. 2021 Mar; 35(3): e23672. Published online 2020 Nov 30. doi: 10.1002/jcla.23672

PMCID:: PMC7957982

Abstract Article PDF–443K

Select item 73992727.

MTP Gene Variants and Response to Lomitapide in Patients with Homozygous Familial Hypercholesterolemia

Genovefa D Kolovou, Vana Kolovou, Anna Papadopoulou, Gerald F Watts

J Atheroscler Thromb. 2016 Jul 1; 23(7): 878–883. doi: 10.5551/jat.34777

PMCID:: PMC7399272

Abstract Article PDF–91K

Select item 67950828.

In search of a genetic explanation for LDLc variability in an FH family: common SNPs and a rare mutation in MTTP explain only part of LDL variability in an FH family

Michael Winther, Shoshi Shpitzen, Or Yaacov, Jakob Landau, Limor Oren, Linda Foroozan-Rosenberg, Naama Lev Cohain, Daniel Schurr, Vardiela Meiner, Auryan Szalat, Shai Carmi, Michael R. Hayden, Eran Leitersdorf, Ronen Durst

J Lipid Res. 2019 Oct; 60(10): 1733–1740. Published online 2019 Aug 6. doi: 10.1194/jlr.M092049

PMCID:: PMC6795082

Abstract Article PDF–696K

Select item 67173009.

The crystal structure of human microsomal triglyceride transfer protein

Ekaterina I. Biterova, Michail N. Isupov, Ronan M. Keegan, Andrey A. Lebedev, Anil A. Sohail, Inam Liaqat, Heli I. Alanen, Lloyd W. Ruddock

Proc Natl Acad Sci U S A. 2019 Aug 27; 116(35): 17251–17260. Published online 2019 Aug 8. doi: 10.1073/pnas.1903029116

PMCID:: PMC6717300

Abstract Article PDF–2.5M

Select item 561720310.

Association of MTTP gene variants with pediatric NAFLD: A candidate-gene-based analysis of single nucleotide variations in obese children

Dongling Dai, Feiqiu Wen, Shaoming Zhou, Zhe Su, Guosheng Liu, Mingbang Wang, Jianli Zhou, Fusheng He

PLoS One. 2017; 12(9): e0185396. Published online 2017 Sep 27. doi: 10.1371/journal.pone.0185396

PMCID:: PMC5617203

Abstract Article PDF–1.3M

Select item 555507811.

Lack of MTTP protein in pluripotent stem cell-derived hepatocytes/cardiomyocytes abolishes apoB secretion and increases cell stress

Ying Liu, Donna M. Conlon, Xin Bi, Katherine J. Slovik, Jianting Shi, Hailey I. Edelstein, John S. Millar, Ali Javaheri, Marina Cuchel, Evanthia E. Pashos, Jahangir Iqbal, M. Mahmood Hussain, Robert A. Hegele, Wenli Yang, Stephen A. Duncan, Daniel J. Rader, Edward E. Morrisey

Cell Rep. Author manuscript; available in PMC 2018 May 16.

Published in final edited form as: Cell Rep. 2017 May 16; 19(7): 1456–1466. doi: 10.1016/j.celrep.2017.04.064

PMCID:: PMC5555078

Abstract Article PDF–1.2M

Select item 537231712.

Genetic variation in the microsomal triglyceride transfer protein (−493G/T) is associated with hepatic steatosis in patients infected with hepatitis C virus

Mariana Cavalheiro Magri, Thamiris Vaz Gago Prata, Caroline Manchiero, Bianca Peixoto Dantas, Celso Carmo Mazza, Fátima Mitiko Tengan

BMC Infect Dis. 2017; 17: 235. Published online 2017 Mar 29. doi: 10.1186/s12879-017-2340-x

PMCID:: PMC5372317

Abstract Article PDF–486K

Select item 489167213.

Discovery of Novel Splice Variants and Regulatory Mechanisms for Microsomal Triglyceride Transfer Protein in Human Tissues

Takashi Suzuki, Larry L. Swift

Sci Rep. 2016; 6: 27308. Published online 2016 Jun 3. doi: 10.1038/srep27308

PMCID:: PMC4891672

Abstract Article PDF–998K

Select item 460334014.

MTTP-297H polymorphism reduced serum cholesterol but increased risk of non-alcoholic fatty liver disease-a cross-sectional study

Pi-Jung Hsiao, Mei-Yueh Lee, Yeng-Tseng Wang, He-Jiun Jiang, Pi-Chen Lin, Yi-Hsin Connie Yang, Kung-Kai Kuo

BMC Med Genet. 2015; 16: 93. Published online 2015 Oct 12. doi: 10.1186/s12881-015-0242-6

PMCID:: PMC4603340

Abstract Article PDF–1.0M

Select item 421545315.

A Polymorphism in the Microsomal Triglyceride Transfer Protein Can Predict the Response to Antiviral Therapy in Egyptian Patients with Chronic Hepatitis C Virus Genotype 4 Infection

Yasmin Saad, Olfat Shaker, Yasser Nassar, Lama Ahmad, Mohamed Said, Gamal Esmat

Gut Liver. 2014 Nov; 8(6): 655–661. Prepublished online 2014 Oct 7. Published online 2014 Nov 1. doi: 10.5009/gnl13374

PMCID:: PMC4215453

Abstract Article PDF–248K

Select item 385413916.

MTP -493G/T gene polymorphism is associated with steatosis in hepatitis C-infected patients

E.R.F. Siqueira, C.P.M.S. Oliveira, M.L. Correa-Giannella, J.T. Stefano, A.M. Cavaleiro, M.A.H.Z. Fortes, M.T.C. Muniz, F.S. Silva, L.M.M.B. Pereira, F.J. Carrilho

Braz J Med Biol Res. 2012 Jan; 45(1): 72–77. Published online 2011 Dec 9. doi: 10.1590/S0100-879X2011007500160

PMCID:: PMC3854139

Abstract Article PDF–311K

Select item 366838717.

Distinguishing Between Longevity and Buffered-Deleterious Genotypes for Exceptional Human Longevity: The Case of the MTP Gene

Derek M. Huffman, Joris Deelen, Kenny Ye, Aviv Bergman, Eline P. Slagboom, Nir Barzilai, Gil Atzmon

J Gerontol A Biol Sci Med Sci. 2012 Nov; 67(11): 1153–1160. Published online 2012 Apr 10. doi: 10.1093/gerona/gls103

PMCID:: PMC3668387

Abstract Article PDF–491K

Select item 363248918.

Molecular characterization of Tunisian families with abetalipoproteinemia and identification of a novel mutation in MTTP gene

Mohamed Najah, Sarraj Mohamed Youssef, Hrira Mohamed Yahia, Slimani Afef, Jelassi Awatef, Hammami Saber, Najjar Mohamed Fadhel, Agnès Sassolas, Slimane Mohamed Naceur

Diagn Pathol. 2013; 8: 54. Published online 2013 Apr 4. doi: 10.1186/1746-1596-8-54

PMCID:: PMC3632489

Abstract Article PDF–638K

Select item 356596319.

Microsomal triglyceride transfer protein -164 T > C gene polymorphism and risk of cardiovascular disease: results from the EPIC-Potsdam case-cohort study

Romina di Giuseppe, Sonali Pechlivanis, Eva Fisher, Maria Arregui, Beate Weikert, Sven Knüppel, Brian Buijsse, Andreas Fritsche, Stefan N Willich, Hans-Georg Joost, Heiner Boeing, Susanne Moebus, Cornelia Weikert

BMC Med Genet. 2013; 14: 19. Published online 2013 Jan 29. doi: 10.1186/1471-2350-14-19

PMCID:: PMC3565963

Abstract Article PDF–241K

Select item 355448420.

Microsomal triglyceride transfer protein gene -493G/T polymorphism and its association with serum lipid levels in Bama Zhuang long-living families in China

Shang-Ling Pan, Xiao-Qiu Luo, Ze-Ping Lu, Shao-Hua Lu, Huan Luo, Cheng-Wu Liu, Cai-You Hu, Ming Yang, Li-Li Du, Zhen Song, Guo-Fang Pang, Hua-Yu Wu, Jin-Bo Huang, Jun-Hua Peng, Rui-Xing Yin

Lipids Health Dis. 2012; 11: 177. Published online 2012 Dec 28. doi: 10.1186/1476-511X-11-177

PMCID:: PMC3554484

Abstract Article PDF–940K

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PMC Links for Gene (Select 4547) (65)
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microsomal triglyceride transfer protein large subunit isoform 1 precursor [Homo...
microsomal triglyceride transfer protein large subunit isoform 1 precursor [Homo sapiens]
gi|1887447763|ref|NP_001373069.1|

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