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Select item 111586861.

Frequent silencing of a putative tumor suppressor gene melatonin receptor 1 A (MTNR1A) in oral squamous‐cell carcinoma

Erina Nakamura, Ken‐ichi Kozaki, Hitoshi Tsuda, Emina Suzuki, Atiphan Pimkhaokham, Gou Yamamoto, Tarou Irie, Tetsuhiko Tachikawa, Teruo Amagasa, Johji Inazawa, Issei Imoto

Cancer Sci. 2008 Jul; 99(7): 1390–1400. Published online 2008 Apr 30. doi: 10.1111/j.1349-7006.2008.00838.x

PMCID:: PMC11158686

Abstract Article PDF–316K

Select item 109729582.

Rs4862705 in the melatonin receptor 1A gene is associated with renal function decline in type 1 diabetes individuals

Gustavo Daher, Daniele Pereira Santos-Bezerra, Ana Mercedes Cavaleiro, Tatiana Souza Pelaes, Sharon Nina Admoni, Ricardo Vessoni Perez, Cleide Guimarães Machado, Fernanda Gaspar do Amaral, José Cipolla-Neto, Maria Lúcia Correa-Giannella

Front Endocrinol (Lausanne) 2024; 15: 1331012. Published online 2024 Mar 14. doi: 10.3389/fendo.2024.1331012

PMCID:: PMC10972958

Abstract Article PDF–499K

Select item 93217703.

Melatonin Reverses the Warburg-Type Metabolism and Reduces Mitochondrial Membrane Potential of Ovarian Cancer Cells Independent of MT1 Receptor Activation

Maira Smaniotto Cucielo, Roberta Carvalho Cesário, Henrique Spaulonci Silveira, Letícia Barbosa Gaiotte, Sérgio Alexandre Alcantara dos Santos, Debora Aparecida Pires de Campos Zuccari, Fábio Rodrigues Ferreira Seiva, Russel J. Reiter, Luiz Gustavo de Almeida Chuffa

Molecules. 2022 Jul; 27(14): 4350. Published online 2022 Jul 7. doi: 10.3390/molecules27144350

PMCID:: PMC9321770

Abstract Article PDF–4.8M

Select item 69820644.

Age Associated Decrease of MT-1 Melatonin Receptor in Human Dermal Skin Fibroblasts Impairs Protection Against UV-Induced DNA Damage

Kelly Dong, Earl Goyarts, Antonella Rella, Edward Pelle, Yung Hou Wong, Nadine Pernodet

Int J Mol Sci. 2020 Jan; 21(1): 326. Published online 2020 Jan 3. doi: 10.3390/ijms21010326

PMCID:: PMC6982064

Abstract Article PDF–1.8M

Select item 66969385.

Structural basis for ligand recognition at the human MT₁ melatonin receptor

Benjamin Stauch, Linda C. Johansson, John D. McCorvy, Nilkanth Patel, Gye Won Han, Xi-Ping Huang, Cornelius Gati, Alexander Batyuk, Samuel T. Slocum, Andrii Ishchenko, Wolfgang Brehm, Thomas A. White, Nairie Michaelian, Caleb Madsen, Lan Zhu, Thomas D. Grant, Jessica M. Grandner, Anna Shiriaeva, Reid H.J. Olsen, Alexandra R. Tribo, Saïd Yous, Raymond C. Stevens, Uwe Weierstall, Vsevolod Katritch, Bryan L. Roth, Wei Liu, Vadim Cherezov

Nature. Author manuscript; available in PMC 2019 Oct 24.

Published in final edited form as: Nature. 2019 May; 569(7755): 284–288. Published online 2019 Apr 24. doi: 10.1038/s41586-019-1141-3

Correction in:: Nature. 2019 May 3

PMCID:: PMC6696938

Abstract Article PDF–2.8M

Select item 60474346.

Melatonin receptor type 1A gene linked to Alzheimer’s disease in old age

Sonja Sulkava, Pranuthi Muggalla, Raimo Sulkava, Hanna M Ollila, Terhi Peuralinna, Liisa Myllykangas, Karri Kaivola, David J Stone, Bryan J Traynor, Alan E Renton, Alberto M Rivera, Seppo Helisalmi, Hilkka Soininen, Tuomo Polvikoski, Mikko Hiltunen, Pentti J Tienari, Henri J Huttunen, Tiina Paunio

Sleep. 2018 Jul; 41(7): zsy103. Published online 2018 Jul 6. doi: 10.1093/sleep/zsy103

PMCID:: PMC6047434

Abstract Article PDF–1.4M

Select item 58124627.

Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies

A. Demirkan, J. Lahti, N. Direk, A. Viktorin, K. L. Lunetta, A. Terracciano, M. A. Nalls, T. Tanaka, K. Hek, M. Fornage, J. Wellmann, M. C. Cornelis, H. M. Ollila, L. Yu, J. A. Smith, L. C. Pilling, A. Isaacs, A. Palotie, W. V. Zhuang, A. Zonderman, J. D. Faul, A. Sutin, O. Meirelles, A. Mulas, A. Hofman, A. Uitterlinden, F. Rivadeneira, M. Perola, W. Zhao, V. Salomaa, K. Yaffe, A. I. Luik, NABEC, UKBEC, Y. Liu, J. Ding, P. Lichtenstein, M. Landén, E. Widen, D. R. Weir, D. J. Llewellyn, A. Murray, S. L. R. Kardia, J. G. Eriksson, K. Koenen, P. K. E. Magnusson, L. Ferrucci, T. H. Mosley, F. Cucca, B. A. Oostra, D. A. Bennett, T. Paunio, K. Berger, T. B. Harris, N. L. Pedersen, J. M. Murabito, H. Tiemeier, C. M. van Duijn, K. Räikkönen

Psychol Med. Author manuscript; available in PMC 2018 Feb 14.

Published in final edited form as: Psychol Med. 2016 Jun; 46(8): 1613–1623. Published online 2016 Mar 21. doi: 10.1017/S0033291715002081

PMCID:: PMC5812462

Abstract Article PDF–344K

Select item 58065578.

Common Genetic Variation Near Melatonin Receptor 1A Gene Linked to Job-Related Exhaustion in Shift Workers

Sonja Sulkava, Hanna M. Ollila, Jukka Alasaari, Sampsa Puttonen, Mikko Härmä, Katriina Viitasalo, Alexandra Lahtinen, Jaana Lindström, Auli Toivola, Raimo Sulkava, Mika Kivimäki, Jussi Vahtera, Timo Partonen, Kaisa Silander, Tarja Porkka-Heiskanen, Tiina Paunio

Sleep. 2017 Jan 1; 40(1): zsw011. Published online 2017 Feb 9. doi: 10.1093/sleep/zsw011

PMCID:: PMC5806557

Abstract Article PDF–683K

Select item 56665449.

Genetic Variations of Melatonin Receptor Type 1A are Associated with the Clinicopathologic Development of Urothelial Cell Carcinoma

Yung-Wei Lin, Shian-Shiang Wang, Yu-Ching Wen, Min-Che Tung, Liang-Ming Lee, Shun-Fa Yang, Ming-Hsien Chien

Int J Med Sci. 2017; 14(11): 1130–1135. Published online 2017 Sep 4. doi: 10.7150/ijms.20629

PMCID:: PMC5666544

Abstract Article PDF–300K

Select item 437372310.

Interactions between Environmental Factors and Melatonin Receptor Type 1A Polymorphism in Relation to Oral Cancer Susceptibility and Clinicopathologic Development

Feng-Yan Lin, Chiao-Wen Lin, Shun-Fa Yang, Wei-Jiunn Lee, Yung-Wei Lin, Liang-Ming Lee, Junn-Liang Chang, Wei-Chun Weng, Chien-Huang Lin, Ming-Hsien Chien

PLoS One. 2015; 10(3): e0121677. Published online 2015 Mar 25. doi: 10.1371/journal.pone.0121677

PMCID:: PMC4373723

Abstract Article PDF–385K

Select item 428475511.

Expression of the MT1 Melatonin Receptor in Ovarian Cancer Cells

Karolina Jablonska, Bartosz Pula, Agata Zemla, Christopher Kobierzycki, Witold Kedzia, Ewa Nowak-Markwitz, Marek Spaczynski, Maciej Zabel, Marzenna Podhorska-Okolow, Piotr Dziegiel

Int J Mol Sci. 2014 Dec; 15(12): 23074–23089. Published online 2014 Dec 12. doi: 10.3390/ijms151223074

PMCID:: PMC4284755

Abstract Article PDF–1.5M

Select item 355235912.

Expression of melatonin receptors in triple negative breast cancer (TNBC) in African American and Caucasian women: relation to survival

Gabriela Oprea-Ilies, Erhard Haus, Linda Sackett-Lundeen, Yuan Liu, Lauren McLendon, Robert Busch, Amy Adams, Cynthia Cohen

Breast Cancer Res Treat. 2013; 137(3): 677–687. Published online 2012 Dec 19. doi: 10.1007/s10549-012-2371-3

PMCID:: PMC3552359

Abstract Article PDF–445K

Select item 314424813.

piR_015520 Belongs to Piwi-Associated RNAs Regulates Expression of the Human Melatonin Receptor 1A Gene

Teresa Esposito, Sara Magliocca, Daniela Formicola, Fernando Gianfrancesco

PLoS One. 2011; 6(7): e22727. Published online 2011 Jul 26. doi: 10.1371/journal.pone.0022727

PMCID:: PMC3144248

Abstract Article PDF–652K

Select item 878693914.

Structural basis of the ligand binding and signaling mechanism of melatonin receptors

Qinggong Wang, Qiuyuan Lu, Qiong Guo, Maikun Teng, Qingguo Gong, Xu Li, Yang Du, Zheng Liu, Yuyong Tao

Nat Commun. 2022; 13: 454. Published online 2022 Jan 24. doi: 10.1038/s41467-022-28111-3

PMCID:: PMC8786939

Abstract Article PDF–2.1M

Select item 639003415.

Genetic polymorphisms of melatonin receptors 1A and 1B may result in disordered lipid metabolism in obese patients with polycystic ovary syndrome

Xiu-Hua Xu, Lian-Cui Kou, Hai-Mei Wang, Chun-Mei Bo, Xiao-Cui Song

Mol Med Rep. 2019 Mar; 19(3): 2220–2230. Published online 2019 Jan 17. doi: 10.3892/mmr.2019.9872

PMCID:: PMC6390034

Abstract Article PDF–1.0M

Select item 584351016.

Nocturnal activation of melatonin receptor type 1 signaling modulates diurnal insulin sensitivity via regulation of PI3K activity

Sharon Owino, Aida Sánchez-Bretaño, Cynthia Tchio, Erika Cecon, Angeliki Karamitri, Julie Dam, Ralf Jockers, Giuseppe Piccione, Hye Lim Noh, Taekyoon Kim, Jason K. Kim, Kenkichi Baba, Gianluca Tosini

J Pineal Res. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: J Pineal Res. 2018 Apr; 64(3): 10.1111/jpi.12462. Published online 2018 Jan 9. doi: 10.1111/jpi.12462

PMCID:: PMC5843510

Abstract Article PDF–2.6M

Select item 437886017.

Human Gastroenteropancreatic Expression of Melatonin and Its Receptors MT1 and MT2

Fanny Söderquist, Per M. Hellström, Janet L. Cunningham

PLoS One. 2015; 10(3): e0120195. Published online 2015 Mar 30. doi: 10.1371/journal.pone.0120195

PMCID:: PMC4378860

Abstract Article PDF–2.2M

Select item 387470618.

Melatonin MT₁ and MT₂ receptors display different molecular pharmacologies only in the G-protein coupled state

Céline Legros, Séverine Devavry, Sarah Caignard, Clémence Tessier, Philippe Delagrange, Christine Ouvry, Jean A Boutin, Olivier Nosjean

Br J Pharmacol. 2014 Jan; 171(1): 186–201. Published online 2013 Dec 10. doi: 10.1111/bph.12457

PMCID:: PMC3874706

Abstract Article PDF–2.9M

Select item 377738519.

Melatonin Pathway Genes and Breast Cancer risk among Chinese women

Sandra L.Deming, Wei Lu, Alicia Beeghly-Fadiel, Ying Zheng, Qiuyin Cai, Jirong Long, Xiao-Ou Shu, Yu-Tang Gao, Wei Zheng

Breast Cancer Res Treat. Author manuscript; available in PMC 2013 Sep 19.

Published in final edited form as: Breast Cancer Res Treat. 2012 Apr; 132(2): 693–699. Published online 2011 Dec 3. doi: 10.1007/s10549-011-1884-5

PMCID:: PMC3777385

Abstract Article PDF–51K

Select item 321369620.

The Melatonin MT1 Receptor Axis Modulates Mutant Huntingtin-Mediated Toxicity

Xin Wang, Ana Sirianni, Zhijuan Pei, Kerry Cormier, Karen Smith, Jiying Jiang, Shuanhu Zhou, Hui Wang, Rong Zhao, Hiroko Yano, Jeong Eun Kim, Wei Li, Bruce S. Kristal, Robert J. Ferrante, Robert M. Friedlander

J Neurosci. 2011 Oct 12; 31(41): 14496–14507. doi: 10.1523/JNEUROSCI.3059-11.2011

PMCID:: PMC3213696

Abstract Article PDF–3.0M

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