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Select item 107896681.

Mineralocorticoid receptor overactivation: targeting systemic impact with non-steroidal mineralocorticoid receptor antagonists

Gianluigi Savarese, Felix Lindberg, Gerasimos Filippatos, Javed Butler, Stefan D. Anker

Diabetologia. 2024; 67(2): 246–262. Published online 2023 Dec 21. doi: 10.1007/s00125-023-06031-1

PMCID:: PMC10789668

Abstract Article PDF–989K

Select item 106942942.

Effects of environmental and genetic interactions on job burnout in coal miners: interactions between occupational stress, coping styles, and NR3C2 gene polymorphisms

Xin Lin, Xiaofan Ma, Xiaoting Yi, Chao Qu, Fuye Li

Front Public Health. 2023; 11: 1237843. Published online 2023 Nov 20. doi: 10.3389/fpubh.2023.1237843

PMCID:: PMC10694294

Abstract Article PDF–245K

Select item 101786373.

Mineralocorticoid Receptor Antagonists for Preventing Chronic Kidney Disease Progression: Current Evidence and Future Challenges

Wataru Fujii, Shigeru Shibata

Int J Mol Sci. 2023 May; 24(9): 7719. Published online 2023 Apr 23. doi: 10.3390/ijms24097719

PMCID:: PMC10178637

Abstract Article PDF–750K

Select item 100983004.

NR3C2 inhibits the proliferation of colorectal cancer via regulating glucose metabolism and phosphorylating AMPK

Hui Liu, Wenqi Lei, Zhigui Li, Xiaodong Wang, Liming Zhou

J Cell Mol Med. 2023 Apr; 27(8): 1069–1082. Published online 2023 Mar 23. doi: 10.1111/jcmm.17706

PMCID:: PMC10098300

Abstract Article PDF–5.0M

Select item 99022175.

Emerging vascular cell-specific roles for mineralocorticoid receptor: implications for understanding sex differences in cardiovascular disease

Nicole L. Wolter, Iris Z. Jaffe

Am J Physiol Cell Physiol. 2023 Jan 1; 324(1): C193–C204. Published online 2022 Nov 28. doi: 10.1152/ajpcell.00372.2022

PMCID:: PMC9902217

Abstract Article

Select item 98198246.

Impact of Mineralocorticoid Receptor Gene NR3C2 on the Prediction of Functional Classification of Left Ventricular Remodeling and Arrhythmia after Acute Myocardial Infarction

Rima Braukyliene, Ali Aldujeli, Ayman Haq, Laurynas Maciulevicius, Darija Jankauskaite, Martynas Jurenas, Ramunas Unikas, Vytautas Zabiela, Vaiva Lesauskaite, Sandrita Simonyte, Diana Zaliaduonytė

Int J Environ Res Public Health. 2023 Jan; 20(1): 12. Published online 2022 Dec 20. doi: 10.3390/ijerph20010012

PMCID:: PMC9819824

Abstract Article PDF–810K

Select item 89083467.

NR3C2 suppresses the proliferation, migration, invasion and angiogenesis of colon cancer cells by inhibiting the AKT/ERK signaling pathway

Jia Li, Zhao Xu

Mol Med Rep. 2022 Apr; 25(4): 133. Published online 2022 Feb 18. doi: 10.3892/mmr.2022.12649

PMCID:: PMC8908346

Abstract Article PDF–7.6M

Select item 82748088.

The Cardiac Mineralocorticoid Receptor (MR): A Therapeutic Target Against Ventricular Arrhythmias

Michel F. Rossier

Front Endocrinol (Lausanne) 2021; 12: 694758. Published online 2021 Jun 28. doi: 10.3389/fendo.2021.694758

PMCID:: PMC8274808

Abstract Article PDF–728K

Select item 78674509.

Jianjun Lu, Fang Hu, Yingling Zhou

Biomed Res Int. 2021; 2021: 9025481. Published online 2021 Jan 28. doi: 10.1155/2021/9025481

PMCID:: PMC7867450

Abstract Article PDF–15M

Select item 750701310.

Functional polymorphisms of the mineralocorticoid receptor gene NR3C2 are associated with diminished memory decline: Results from a longitudinal general‐population study

Jan Terock, Sandra Van der Auwera, Deborah Janowitz, Katharina Wittfeld, Alexander Teumer, Hans J. Grabe

Mol Genet Genomic Med. 2020 Sep; 8(9): e1345. Published online 2020 Jun 18. doi: 10.1002/mgg3.1345

PMCID:: PMC7507013

Abstract Article PDF–1014K

Select item 692258911.

NR3C2 gene polymorphism is associated with risk of gestational hypertension in Han Chinese women

Zhenghui Cui, Jianyun Xu, Wenying Jiang

Medicine (Baltimore) 2019 Dec; 98(50): e18215. Published online 2019 Dec 16. doi: 10.1097/MD.0000000000018215

PMCID:: PMC6922589

Abstract Article PDF–666K

Select item 584710812.

Association of a Haplotype in the NR3C2 Gene, Encoding the Mineralocorticoid Receptor, With Chronic Central Serous Chorioretinopathy

Elon H. C. van Dijk, Rosa L. Schellevis, Maaike G. J. M. van Bergen, Myrte B. Breukink, Lebriz Altay, Paula Scholz, Sascha Fauser, Onno C. Meijer, Carel B. Hoyng, Anneke I. den Hollander, Camiel J. F. Boon, Eiko K. de Jong

JAMA Ophthalmol. 2017 May; 135(5): 446–451. Published online 2017 Mar 23. doi: 10.1001/jamaophthalmol.2017.0245

PMCID:: PMC5847108

Abstract Article

Select item 568759613.

A Haplotype Associated with Enhanced Mineralocorticoid Receptor Expression Facilitates the Stress-Induced Shift from “Cognitive” to “Habit” Learning

Lisa Wirz, Martin Reuter, Jan Wacker, Andrea Felten, Lars Schwabe

eNeuro. 2017 Nov-Dec; 4(6): ENEURO.0359-17.2017. Prepublished online 2017 Nov 13. Published online 2017 Nov 15. doi: 10.1523/ENEURO.0359-17.2017

PMCID:: PMC5687596

Abstract Article PDF–783K

Select item 568168814.

Modulation of transcriptional mineralocorticoid receptor activity by casein kinase 2

Stefanie Ruhs, Nicole Strätz, Katja Quarch, Antonia Masch, Mike Schutkowski, Michael Gekle, Claudia Grossmann

Sci Rep. 2017; 7: 15340. Published online 2017 Nov 10. doi: 10.1038/s41598-017-15418-1

PMCID:: PMC5681688

Abstract Article PDF–4.3M

Select item 541739515.

Conformation of the Mineralocorticoid Receptor N-terminal Domain: Evidence for Induced and Stable Structure

Katharina Fischer, Sharon M. Kelly, Kate Watt, Nicholas C. Price, Iain J. McEwan

Mol Endocrinol. October 1, 2010; 24(10): 1935–1948. doi: 10.1210/me.2010-0005

PMCID:: PMC5417395

Abstract Article

Select item 541019016.

Role of mineralocorticoid receptor activation in cardiac diastolic dysfunction

Guanghong Jia, Yan Jia, James R. Sowers

Biochim Biophys Acta. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Biochim Biophys Acta. 2017 Aug; 1863(8): 2012–2018. Published online 2016 Oct 29. doi: 10.1016/j.bbadis.2016.10.025

PMCID:: PMC5410190

Abstract Article PDF–1.1M

Select item 509541617.

Mineralocorticoid Receptor (MR) trans-Activation of Inflammatory AP-1 Signaling: DEPENDENCE ON DNA SEQUENCE, MR CONFORMATION, AND AP-1 FAMILY MEMBER EXPRESSION

Edward J. Dougherty, Jason M. Elinoff, Gabriela A. Ferreyra, Angela Hou, Rongman Cai, Junfeng Sun, Kevin P. Blaine, Shuibang Wang, Robert L. Danner

J Biol Chem. 2016 Nov 4; 291(45): 23628–23644. Published online 2016 Sep 20. doi: 10.1074/jbc.M116.732248

PMCID:: PMC5095416

Abstract Article PDF–1.8M

Select item 483947418.

Renal mineralocorticoid receptor and electrolyte homeostasis

Andrew S. Terker, David H. Ellison

Am J Physiol Regul Integr Comp Physiol. 2015 Nov 1; 309(9): R1068–R1070. Published online 2015 Jul 1. doi: 10.1152/ajpregu.00135.2015

PMCID:: PMC4839474

Abstract Article

Select item 471524419.

Associations of Renin–Angiotensin–Aldosterone System Genes With Blood Pressure Changes and Hypertension Incidence

William J. He, Changwei Li, Dabeeru C. Rao, James E. Hixson, Jianfeng Huang, Jie Cao, Treva K. Rice, Lawrence C. Shimmin, Dongfeng Gu, Tanika N. Kelly

Am J Hypertens. 2015 Nov; 28(11): 1310–1315. Published online 2015 Mar 28. doi: 10.1093/ajh/hpv033