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Select item 101077811.

MBNL‐dependent impaired development within the neuromuscular system in myotonic dystrophy type 1

Julie Tahraoui‐Bories, Antoine Mérien, Anchel González‐Barriga, Jeanne Lainé, Céline Leteur, Hélène Polvèche, Alexandre Carteron, Juliette Duchesne De Lamotte, Camille Nicoleau, Jérome Polentes, Margot Jarrige, Mário Gomes‐Pereira, Erwann Ventre, Pauline Poydenot, Denis Furling, Laurent Schaeffer, Claire Legay, Cécile Martinat

Neuropathol Appl Neurobiol. 2023 Feb; 49(1): e12876. Published online 2023 Jan 17. doi: 10.1111/nan.12876

PMCID:: PMC10107781

Article PDF–6.2M

Select item 97809712.

Cognate RNA-Binding Modes by the Alternative-Splicing Regulator MBNL1 Inferred from Molecular Dynamics

Àlex L. González, Daniel Fernández-Remacha, José Ignacio Borrell, Jordi Teixidó, Roger Estrada-Tejedor

Int J Mol Sci. 2022 Dec; 23(24): 16147. Published online 2022 Dec 18. doi: 10.3390/ijms232416147

PMCID:: PMC9780971

Article PDF–5.0M

Select item 81263363.

Altered Expression of MBNL Family of Alternative Splicing Factors in Colorectal Cancer

NAZILA NAVVABI, PAVLA KOLIKOVA, PETR HOSEK, FRANTISEK ZITRICKY, AZITA NAVVABI, ONDREJ VYCITAL, JAN BRUHA, RICHARD PALEK, JACHYM ROSENDORF, VACLAV LISKA, PAVEL PITULE

Cancer Genomics Proteomics. 2021 May-Jun; 18(3): 295–306. Published online 2021 May 3. doi: 10.21873/cgp.20260

PMCID:: PMC8126336

Article PDF–750K

Select item 80853674.

MBNL1 Suppressed Cancer Metastatic of Skin Squamous Cell Carcinoma Via by TIAL1/MYOD1/Caspase-9/3 Signaling Pathways

Jiaorong Chen, Jiaqi Wang, Jingyi Qian, Mengying Bao, Xin Zhang, Zheng Huang

Technol Cancer Res Treat. 2021; 20: 1533033820960755. Published online 2021 Apr 26. doi: 10.1177/1533033820960755

PMCID:: PMC8085367

Article PDF–1.1M

Select item 76421705.

The Alternative Splicing Factor MBNL1 Inhibits Glioblastoma Tumor Initiation and Progression by Reducing Hypoxia-induced Stemness

Dillon M. Voss, Anthony Sloan, Raffaella Spina, Heather M. Ames, Eli E. Bar

Cancer Res. Author manuscript; available in PMC 2021 May 1.

Published in final edited form as: Cancer Res. 2020 Nov 1; 80(21): 4681–4692. Published online 2020 Sep 14. doi: 10.1158/0008-5472.CAN-20-1233

PMCID:: PMC7642170

Article PDF–1.8M

Select item 73688616.

MBNL1 reverses the proliferation defect of skeletal muscle satellite cells in myotonic dystrophy type 1 by inhibiting autophagy via the mTOR pathway

Kai-Yi Song, Xiu-Ming Guo, Hui-Qi Wang, Lei Zhang, Si-Yuan Huang, Ying-Chao Huo, Gang Zhang, Jin-Zhou Feng, Rong-Rong Zhang, Yue Ma, Qing-Zhe Hu, Xin-Yue Qin

Cell Death Dis. 2020 Jul; 11(7): 545. Published online 2020 Jul 18. doi: 10.1038/s41419-020-02756-8

PMCID:: PMC7368861

Article PDF–5.5M

Select item 61585047.

MBNL splicing activity depends on RNA binding site structural context

Katarzyna Taylor, Łukasz J Sznajder, Piotr Cywoniuk, James D Thomas, Maurice S Swanson, Krzysztof Sobczak

Nucleic Acids Res. 2018 Sep 28; 46(17): 9119–9133. Published online 2018 Jun 28. doi: 10.1093/nar/gky565

PMCID:: PMC6158504

Article PDF–898K

Select item 57860168.

MBNL expression in autoregulatory feedback loops

Patryk Konieczny, Ewa Stepniak-Konieczna, Krzysztof Sobczak

RNA Biol. 2018; 15(1): 1–8. Published online 2017 Nov 13. doi: 10.1080/15476286.2017.1384119

PMCID:: PMC5786016

Article PDF–735K

Select item 47624249.

Muscleblind-like 1 suppresses breast cancer metastatic colonization and stabilizes metastasis suppressor transcripts

Lisa Fish, Nora Pencheva, Hani Goodarzi, Hien Tran, Mitsukuni Yoshida, Sohail F. Tavazoie

Genes Dev. 2016 Feb 15; 30(4): 386–398. doi: 10.1101/gad.270645.115

PMCID:: PMC4762424

Article PDF–1.1M

Select item 468932210.

Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1

Marianna Teplova, Dinshaw J. Patel

Nat Struct Mol Biol. Author manuscript; available in PMC 2015 Dec 23.

Published in final edited form as: Nat Struct Mol Biol. 2008 Dec; 15(12): 1343–1351. Published online 2008 Nov 30. doi: 10.1038/nsmb.1519

PMCID:: PMC4689322

Article PDF–1.7M

Select item 389043811.

MBNL1-RNA Recognition: Contributions of MBNL1 Sequence and RNA Conformation

Yuan Fu, Dr. Sreenivasa Rao Ramisetty, Nejmun Hussain, Anne M. Baranger

Chembiochem. Author manuscript; available in PMC 2014 Jan 14.

Published in final edited form as: Chembiochem. 2012 Jan 2; 13(1): 112–119. Published online 2011 Nov 22. doi: 10.1002/cbic.201100487

PMCID:: PMC3890438

Article PDF–1.8M

Select item 388058812.

Dissecting domains necessary for activation and repression of splicing by muscleblind-like protein 1

Christopher Edge, Clare Gooding, Christopher WJ Smith

BMC Mol Biol. 2013; 14: 29. Published online 2013 Dec 27. doi: 10.1186/1471-2199-14-29

PMCID:: PMC3880588

Article PDF–3.1M

Select item 379434113.

Muscleblind-like1 Undergoes Ectopic Relocation in the Nuclei of Skeletal Muscles in Myotonic Dystrophy and Sarcopenia

M. Malatesta, M. Giagnacovo, M. Costanzo, B. Cisterna, R. Cardani, G. Meola

Eur J Histochem. 2013 Apr 15; 57(2): e15. Published online 2013 Apr 22. doi: 10.4081/ejh.2013.e15

PMCID:: PMC3794341

Article PDF–194K

Select item 349951114.

RNA Splicing Is Responsive to MBNL1 Dose

Sonali P. Jog, Sharan Paul, Warunee Dansithong, Stephanie Tring, Lucio Comai, Sita Reddy

PLoS One. 2012; 7(11): e48825. Published online 2012 Nov 15. doi: 10.1371/journal.pone.0048825

PMCID:: PMC3499511

Article PDF–763K

Select item 345733415.

Combinatorial Mutagenesis of MBNL1 Zinc Fingers Elucidates Distinct Classes of Regulatory Events

Jamie Purcell, Julia C. Oddo, Eric T. Wang, J. Andrew Berglund

Mol Cell Biol. 2012 Oct; 32(20): 4155–4167. doi: 10.1128/MCB.00274-12

PMCID:: PMC3457334

Article PDF–2.3M

Select item 319076516.

Autoregulated Splicing of muscleblind-like 1 (MBNL1) Pre-mRNA

Devika P. Gates, Leslie A. Coonrod, J. Andrew Berglund

J Biol Chem. 2011 Sep 30; 286(39): 34224–34233. Published online 2011 Aug 9. doi: 10.1074/jbc.M111.236547

PMCID:: PMC3190765

Article PDF–1.3M

Select item 310343117.

The four Zn fingers of MBNL1 provide a flexible platform for recognition of its RNA binding elements

Danielle Cass, Rachel Hotchko, Paul Barber, Kimberly Jones, Devika P Gates, J Andrew Berglund

BMC Mol Biol. 2011; 12: 20. Published online 2011 May 6. doi: 10.1186/1471-2199-12-20

PMCID:: PMC3103431

Article PDF–4.4M

Select item 309124918.

Analysis of Exonic Regions Involved in Nuclear Localization, Splicing Activity, and Dimerization of Muscleblind-like-1 Isoforms

Hélène Tran, Nathalie Gourrier, Camille Lemercier-Neuillet, Claire-Marie Dhaenens, Audrey Vautrin, Francisco José Fernandez-Gomez, Ludovic Arandel, Céline Carpentier, Hélène Obriot, Sabiha Eddarkaoui, Lucie Delattre, Edwige Van Brussels, Ian Holt, Glenn E. Morris, Bernard Sablonnière, Luc Buée, Nicolas Charlet-Berguerand, Susanna Schraen-Maschke, Denis Furling, Isabelle Behm-Ansmant, Christiane Branlant, Marie-Laure Caillet-Boudin, Nicolas Sergeant

J Biol Chem. 2011 May 6; 286(18): 16435–16446. Published online 2011 Mar 18. doi: 10.1074/jbc.M110.194928

PMCID:: PMC3091249

Article PDF–2.0M

Select item 291910619.

Muscleblind-like 1 (Mbnl1) Promotes Insulin Receptor Exon 11 Inclusion via Binding to a Downstream Evolutionarily Conserved Intronic Enhancer

Supriya Sen, Indrani Talukdar, Ying Liu, Joseph Tam, Sita Reddy, Nicholas J. G. Webster

J Biol Chem. 2010 Aug 13; 285(33): 25426–25437. Published online 2010 Jun 2. doi: 10.1074/jbc.M109.095224

PMCID:: PMC2919106

Article PDF–1.6M

Select item 275252220.

A simple ligand that selectively targets CUG trinucleotide repeats and inhibits MBNL protein binding

Jonathan F. Arambula, Sreenivasa Rao Ramisetty, Anne M. Baranger, Steven C. Zimmerman

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16068–16073. Published online 2009 Sep 8. doi: 10.1073/pnas.0901824106

PMCID:: PMC2752522

Article PDF–1.0M

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