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Items: 1 to 20 of 39

1.
A Rare Mutation in SMAD9 Associated With High Bone Mass Identifies the SMAD‐Dependent BMP Signaling Pathway as a Potential Anabolic Target for Osteoporosis
Celia L Gregson, Dylan J. M. Bergen, Paul Leo, Richard B Sessions, Lawrie Wheeler, April Hartley, Scott Youlten, Peter I Croucher, Aideen M McInerney‐Leo, William Fraser, Jonathan CY Tang, Lisa Anderson, Mhairi Marshall, Leon Sergot, Lavinia Paternoster, George Davey Smith, The AOGC Consortium, Matthew A Brown, Chrissy Hammond, John P Kemp, Jon H Tobias, Emma L Duncan
J Bone Miner Res. 2020 Jan; 35(1): 92–105. Published online 2019 Nov 14. doi: 10.1002/jbmr.3875
PMCID:
PMC7004081
AbstractArticlePDF–1.8M
2.
Smad9 is a new type of transcriptional regulator in bone morphogenetic protein signaling
S. Tsukamoto, T. Mizuta, M. Fujimoto, S. Ohte, K. Osawa, A. Miyamoto, K. Yoneyama, E. Murata, A. Machiya, E. Jimi, S. Kokabu, T. Katagiri
Sci Rep. 2014; 4: 7596. Published online 2014 Dec 23. doi: 10.1038/srep07596
PMCID:
PMC4274517
AbstractArticlePDF–1.3M
3.
Association of the gene polymorphisms of BMPR2, ACVRL1, SMAD9 and their interactions with the risk of essential hypertension in the Chinese Han population
Yunpeng Chen, Chenxi Ye, Jingwen Chen, Dongming Lin, Hao Wang, Shen Wang
Biosci Rep. 2019 Jan 31; 39(1): BSR20181217. Prepublished online 2019 Jan 7. Published online 2019 Jan 25. doi: 10.1042/BSR20181217
PMCID:
PMC6350070
AbstractArticlePDF–964K
4.
Differential expression of TGF-β superfamily members and role of Smad1/5/9-signalling in chondral versus endochondral chondrocyte differentiation
Verena Dexheimer, Jessica Gabler, Katharina Bomans, Tanja Sims, Georg Omlor, Wiltrud Richter
Sci Rep. 2016; 6: 36655. Published online 2016 Nov 16. doi: 10.1038/srep36655
PMCID:
PMC5111074
AbstractArticlePDF–1.9M
5.
Activated NF-κB in Bone Marrow Mesenchymal Stem Cells from Systemic Lupus Erythematosus Patients Inhibits Osteogenic Differentiation Through Downregulating Smad Signaling
Yu Tang, Hao Xie, Jinyun Chen, Linyu Geng, Haifeng Chen, Xia Li, Yayi Hou, Liwei Lu, Songtao Shi, Xiaofeng Zeng, Lingyun Sun
Stem Cells Dev. 2013 Feb 15; 22(4): 668–678. Published online 2012 Aug 16. doi: 10.1089/scd.2012.0226
PMCID:
PMC3564481
AbstractArticlePDF–710K
6.
Inhibition of mTORC1 Kinase Activates Smads 1 and 5 but not Smad8 in Human Prostate Cancer Cells, Mediating Cytostatic Response to Rapamycin
Reema S. Wahdan-Alaswad, Kara L. Bane, Kyung Song, Dorjee T.N. Shola, Jorge A. Garcia, David Danielpour
Mol Cancer Res. Author manuscript; available in PMC 2013 Jan 28.
Published in final edited form as: Mol Cancer Res. 2012 Jun; 10(6): 821–833. Published online 2012 Mar 27. doi: 10.1158/1541-7786.MCR-11-0615
Correction in:
Mol Cancer Res. 2017 Nov 30
PMCID:
PMC3557528
AbstractArticlePDF–3.3M
7.
Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells
Wei Wang, Francesca V. Mariani, Richard M. Harland, Kunxin Luo
Proc Natl Acad Sci U S A. 2000 Dec 19; 97(26): 14394–14399. doi: 10.1073/pnas.97.26.14394
PMCID:
PMC18929
AbstractArticlePDF–306K
8.
BMP4-Smad Signaling Pathway Mediates Adriamycin-induced Premature Senescence in Lung Cancer Cells
Dongmei Su, Shan Zhu, Xuefang Han, Yunpeng Feng, Hui Huang, Guoling Ren, Lina Pan, Yu Zhang, Jun Lu, Baiqu Huang
J Biol Chem. 2009 May 1; 284(18): 12153–12164. doi: 10.1074/jbc.M807930200
PMCID:
PMC2673284
AbstractArticlePDF–1.0M
9.
Nuclear Export of Smads by RanBP3L Regulates Bone Morphogenetic Protein Signaling and Mesenchymal Stem Cell Differentiation
Fenfang Chen, Xia Lin, Pinglong Xu, Zhengmao Zhang, Yanzhen Chen, Chao Wang, Jiahuai Han, Bin Zhao, Mu Xiao, Xin-Hua Feng
Mol Cell Biol. 2015 May; 35(10): 1700–1711. Prepublished online 2015 Mar 9. Published online 2015 Apr 21. doi: 10.1128/MCB.00121-15
Correction in:
Mol Cell Biol. 2017 Sep 1; 37(17): e00287-17.
PMCID:
PMC4405638
AbstractArticlePDF–3.6M
10.
Smad7 Protein Interacts with Receptor-regulated Smads (R-Smads) to Inhibit Transforming Growth Factor-β (TGF-β)/Smad Signaling
Xiaohua Yan, Hongwei Liao, Minzhang Cheng, Xiaojing Shi, Xia Lin, Xin-Hua Feng, Ye-Guang Chen
J Biol Chem. 2016 Jan 1; 291(1): 382–392. Published online 2015 Nov 10. doi: 10.1074/jbc.M115.694281
PMCID:
PMC4697173
AbstractArticlePDF–3.0M
11.
Holding Their Own: The Noncanonical Roles of Smad Proteins
Loretta L. Hoover, Steven W. Kubalak
Sci Signal. Author manuscript; available in PMC 2010 Aug 2.
Published in final edited form as: Sci Signal. 2008 Nov 18; 1(46): pe48. Published online 2008 Nov 18. doi: 10.1126/scisignal.146pe48
PMCID:
PMC2913314
AbstractArticlePDF–385K
12.
Endoglin Promotes Transforming Growth Factor β-mediated Smad 1/5/8 Signaling and Inhibits Endothelial Cell Migration through Its Association with GIPC
Nam Y. Lee, Bridgette Ray, Tam How, Gerard C. Blobe
J Biol Chem. 2008 Nov 21; 283(47): 32527–32533. doi: 10.1074/jbc.M803059200
PMCID:
PMC2583306
AbstractArticlePDF–427K
13.
Vascular MADs: Two novel MAD-related genes selectively inducible by flow in human vascular endothelium
James N. Topper, Jiexing Cai, Yubin Qiu, Keith R. Anderson, Yong-Yao Xu, James D. Deeds, Roslyn Feeley, Carlos J. Gimeno, Elizabeth A. Woolf, Olga Tayber, Gail G. Mays, Barbara A. Sampson, Frederick J. Schoen, Michael A. Gimbrone, Jr., Dean Falb
Proc Natl Acad Sci U S A. 1997 Aug 19; 94(17): 9314–9319. doi: 10.1073/pnas.94.17.9314
PMCID:
PMC23174
AbstractArticlePDF–670K
14.
B-Cell Translocation Gene 2 (Btg2) Regulates Vertebral Patterning by Modulating Bone Morphogenetic Protein/Smad Signaling
Sean Park, Young Jae Lee, Ho-Jae Lee, Tsugio Seki, Kwon-Ho Hong, Joonil Park, Hideyuki Beppu, In Kyung Lim, Ji-Won Yoon, En Li, Seong-Jin Kim, S. Paul Oh
Mol Cell Biol. 2004 Dec; 24(23): 10256–10262. doi: 10.1128/MCB.24.23.10256-10262.2004
PMCID:
PMC529031
AbstractArticlePDF–430K
15.
Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor
Akiko Hata, Giorgio Lagna, Joan Massagué, Ali Hemmati-Brivanlou
Genes Dev. 1998 Jan 15; 12(2): 186–197. doi: 10.1101/gad.12.2.186
PMCID:
PMC316444
AbstractArticlePDF–831K
16.
Down-regulation of BMPR Axis during HIV-1 and Cocaine-mediated Pulmonary Smooth Muscle Hyperplasia: Implications for HRPAH
Pranjali Dalvi, Amy O’Brien-Ladner, Navneet K. Dhillon
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2014 Nov 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 Nov; 33(11): 10.1161/ATVBAHA.113.302054. Published online 2013 Sep 5. doi: 10.1161/ATVBAHA.113.302054
Correction in:
volume 34 on page e24
PMCID:
PMC3855352
AbstractArticlePDF–1.3M
17.
Dual role of the Smad4/DPC4 tumor suppressor in TGFβ-inducible transcriptional complexes
Fang Liu, Celio Pouponnot, Joan Massagué
Genes Dev. 1997 Dec 1; 11(23): 3157–3167. doi: 10.1101/gad.11.23.3157
PMCID:
PMC316747
AbstractArticlePDF–1.1M
18.
Computational modelling of Smad-mediated negative feedback and crosstalk in the TGF-β superfamily network
Daniel Nicklas, Leonor Saiz
J R Soc Interface. 2013 Sep 6; 10(86): 20130363. doi: 10.1098/rsif.2013.0363
PMCID:
PMC3730684
AbstractArticlePDF–875K
19.
Quantitative Proteomics of the SMAD (Suppressor of Mothers against Decapentaplegic) Transcription Factor Family Identifies Importin 5 as a Bone Morphogenic Protein Receptor SMAD-specific Importin
Roy Baas, Ayestha Sijm, Hetty A. A. M. van Teeffelen, Robert van Es, Harmjan R. Vos, H. Th. Marc Timmers
J Biol Chem. 2016 Nov 11; 291(46): 24121–24132. Published online 2016 Oct 4. doi: 10.1074/jbc.M116.748582
PMCID:
PMC5104937
AbstractArticlePDF–4.4M
20.
A Massively Parallel Pipeline to Clone DNA Variants and Examine Molecular Phenotypes of Human Disease Mutations
Xiaomu Wei, Jishnu Das, Robert Fragoza, Jin Liang, Francisco M. Bastos de Oliveira, Hao Ran Lee, Xiujuan Wang, Matthew Mort, Peter D. Stenson, David N. Cooper, Steven M. Lipkin, Marcus B. Smolka, Haiyuan Yu
PLoS Genet. 2014 Dec; 10(12): e1004819. Published online 2014 Dec 11. doi: 10.1371/journal.pgen.1004819
PMCID:
PMC4263371
AbstractArticlePDF–7.6M

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