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Select item 76433641.

TM4SF1 promotes EMT and cancer stemness via the Wnt/β-catenin/SOX2 pathway in colorectal cancer

Qiang Tang, Jinhuang Chen, Ziyang Di, Wenzheng Yuan, Zili Zhou, Zhengyi Liu, Shengbo Han, Yanwei Liu, Guoguang Ying, Xiaogang Shu, Maojun Di

J Exp Clin Cancer Res. 2020; 39: 232. Published online 2020 Nov 5. doi: 10.1186/s13046-020-01690-z

PMCID:: PMC7643364

Abstract Article PDF–5.5M

Select item 64198132.

TM4SF1 is a potential target for anti-invasion and metastasis in ovarian cancer

Caiyun Gao, Hongyu Yao, Huimin Liu, Yanying Feng, Zhijun Yang

BMC Cancer. 2019; 19: 237. Published online 2019 Mar 15. doi: 10.1186/s12885-019-5417-7

PMCID:: PMC6419813

Abstract Article PDF–5.9M

Select item 60107563.

Clinical significance of TM4SF1 as a tumor suppressor gene in gastric cancer

Xing‐Chun Peng, Zhi Zeng, Yu‐Ning Huang, Yun‐Chao Deng, Guo‐Hui Fu

Cancer Med. 2018 Jun; 7(6): 2592–2600. Published online 2018 Apr 17. doi: 10.1002/cam4.1494

PMCID:: PMC6010756

Abstract Article PDF–811K

Select item 46924384.

TM4SF1 Promotes Gemcitabine Resistance of Pancreatic Cancer In Vitro and In Vivo

Jia Cao, Jiachun Yang, Vijaya Ramachandran, Thiruvengadam Arumugam, Defeng Deng, Zhaoshen Li, Leiming Xu, Craig D. Logsdon

PLoS One. 2015; 10(12): e0144969. Published online 2015 Dec 28. doi: 10.1371/journal.pone.0144969

PMCID:: PMC4692438

Abstract Article PDF–1.3M

Select item 45838825.

Role of TM4SF1 in regulating breast cancer cell migration and apoptosis through PI3K/AKT/mTOR pathway

Yonghong Sun, Yahong Xu, Jie Xu, Dan Lu, Jianyu Wang

Int J Clin Exp Pathol. 2015; 8(8): 9081–9088. Published online 2015 Aug 1.

PMCID:: PMC4583882

Abstract Article PDF–618K

Select item 45790966.

Intracellular Distribution of TM4SF1 and Internalization of TM4SF1-antibody Complex in Vascular Endothelial Cells

Tracey E. Sciuto, Anne Merley, Chi-Iou Lin, Douglas Richardson, Yu Liu, Dan Li, Ann M. Dvorak, Harold F. Dvorak, Shou-Ching S. Jaminet

Biochem Biophys Res Commun. Author manuscript; available in PMC 2016 Sep 25.

Published in final edited form as: Biochem Biophys Res Commun. 2015 Sep 25; 465(3): 338–343. Published online 2015 Aug 1. doi: 10.1016/j.bbrc.2015.07.142

PMCID:: PMC4579096

Abstract Article PDF–1.9M

Select item 32987667.

TM4SF1: A tetraspanin-like protein necessary for nanopodia formation and endothelial cell migration

Andrew Zukauskas, Anne Merley, Dan Li, Lay-Hong Ang, Tracey E. Sciuto, Samantha Salman, Ann M. Dvorak, Harold F. Dvorak, Shou-Ching S. Jaminet

Angiogenesis. Author manuscript; available in PMC 2012 Mar 11.

Published in final edited form as: Angiogenesis. 2011 Sep; 14(3): 345–354. Published online 2011 May 29. doi: 10.1007/s10456-011-9218-0

PMCID:: PMC3298766

Abstract Article PDF–3.3M

Select item 23968508.

The tumour-associated antigen L6 (L6-Ag) is recruited to the tetraspanin-enriched microdomains: implication for tumour cell motility

Tamara Lekishvili, Elisa Fromm, Michelle Mujoomdar, Fedor Berditchevski

J Cell Sci. Author manuscript; available in PMC 2008 May 28.

Published in final edited form as: J Cell Sci. 2008 Mar 1; 121(Pt 5): 685–694. Published online 2008 Feb 12. doi: 10.1242/jcs.020347

PMCID:: PMC2396850

Abstract Article PDF–1.9M

Select item 488969.

Cloning and expression of the tumor-associated antigen L6.

J S Marken, G L Schieven, I Hellström, K E Hellström, A Aruffo

Proc Natl Acad Sci U S A. 1992 Apr 15; 89(8): 3503–3507. doi: 10.1073/pnas.89.8.3503

PMCID:: PMC48896

Summary Page Browse PDF–1.5M

Select item 1011242310.

Tm4sf1-marked Endothelial Subpopulation Is Dysregulated in Pulmonary Arterial Hypertension

Jason Hong, Brenda Wong, Caroline Huynh, Brian Tang, Gregoire Ruffenach, Min Li, Soban Umar, Xia Yang, Mansoureh Eghbali

Am J Respir Cell Mol Biol. 2023 Apr 1; 68(4): 381–394. Published online 2022 Oct 17. doi: 10.1165/rcmb.2022-0020OC

PMCID:: PMC10112423

Abstract Article PDF–3.9M

Select item 1011182911.

TM4SF1 upregulates MYH9 to activate the NOTCH pathway to promote cancer stemness and lenvatinib resistance in HCC

Si-bo Yang, Zi-han Zhou, Jin Lei, Xiao-wen Li, Qian Chen, Bo Li, Ye-wei Zhang, Yu-zhen Ge, Shi Zuo

Biol Direct. 2023; 18: 18. Published online 2023 Apr 17. doi: 10.1186/s13062-023-00376-8

PMCID:: PMC10111829

Abstract Article PDF–8.1M

Select item 928345612.

TM4SF1 promotes esophageal squamous cell carcinoma metastasis by interacting with integrin α6

Sicong Hou, Xin Hao, Jiajia Li, Siwei Weng, Jiaxin Wang, Tiantian Zhao, Wenqian Li, Xiaolin Hu, Bing Deng, Jianguo Gu, Qinglei Hang

Cell Death Dis. 2022 Jul; 13(7): 609. Published online 2022 Jul 14. doi: 10.1038/s41419-022-05067-2

PMCID:: PMC9283456

Abstract Article PDF–4.1M

Select item 920676113.

Long Noncoding RNA BCYRN1 Recruits BATF to Promote TM4SF1 Upregulation and Enhance HCC Cell Proliferation and Invasion

Ya Liu, Meng-jie Liu, Min Jiao, Li-li Jiang, Xiao Fu, Wen-juan Wang

Dis Markers. 2022; 2022: 1561607. Published online 2022 Jun 11. doi: 10.1155/2022/1561607

PMCID:: PMC9206761

Abstract Article PDF–2.0M

Select item 793392514.

TM4SF1, a binding protein of DVL2 in hepatocellular carcinoma, positively regulates beta‐catenin/TCF signalling

ChuanrRong Zhu, XiaoLing Luo, JinSheng Wu, YuTing Liu, Lei Liu, ShiJie Ma, Rui Xie, ShaoChuang Wang, Wu Ji

J Cell Mol Med. 2021 Mar; 25(5): 2356–2364. Published online 2019 Dec 26. doi: 10.1111/jcmm.14787

PMCID:: PMC7933925

Abstract Article PDF–1.3M

Select item 627753715.

miR-30 Family Reduction Maintains Self-Renewal and Promotes Tumorigenesis in NSCLC-Initiating Cells by Targeting Oncogene TM4SF1

Yu-Shui Ma, Fei Yu, Xiao-Ming Zhong, Gai-Xia Lu, Xian-Ling Cong, Shao-Bo Xue, Wen-Ting Xie, Li-Kun Hou, Li-Juan Pang, Wei Wu, Wei Zhang, Le-Le Cong, Tie Liu, Hui-Deng Long, Ran Sun, Hong-Yan Sun, Zhong-Wei Lv, Chun-Yan Wu, Da Fu

Mol Ther. 2018 Dec 5; 26(12): 2751–2765. Published online 2018 Sep 13. doi: 10.1016/j.ymthe.2018.09.006

PMCID:: PMC6277537

Abstract Article PDF–4.2M

Select item 614629216.

MiRNA-206 suppresses PGE2-induced colorectal cancer cell proliferation, migration, and invasion by targetting TM4SF1

Young Ran Park, Seung Young Seo, Se Lim Kim, Shi Mao Zhu, Sungkun Chun, Jung-Mi Oh, Min Ro Lee, Seong Hun Kim, In Hee Kim, Seung Ok Lee, Soo Teik Lee, Sang Wook Kim

Biosci Rep. 2018 Oct 31; 38(5): BSR20180664. Prepublished online 2018 Aug 22. Published online 2018 Sep 19. doi: 10.1042/BSR20180664

PMCID:: PMC6146292

Abstract Article PDF–1.5M

Select item 538668317.

TM4SF1 promotes the self-renewal of esophageal cancer stem-like cells and is regulated by miR-141

Lei Xue, Xiying Yu, Xingran Jiang, Xin Deng, Linlin Mao, Liping Guo, Jinhu Fan, Qinqxia Fan, Liuxing Wang, Shih-Hsin Lu

Oncotarget. 2017 Mar 21; 8(12): 19274–19284. Published online 2016 Dec 10. doi: 10.18632/oncotarget.13866

PMCID:: PMC5386683

Abstract Article PDF–4.9M

Select item 417728818.

TM4SF1: a new vascular therapeutic target in cancer

Chi-Iou Lin, Anne Merley, Tracey E. Sciuto, Dan Li, Ann M. Dvorak, Juan M. Melero-Martin, Harold F. Dvorak, Shou-Ching S. Jaminet

Angiogenesis. Author manuscript; available in PMC 2015 Oct 1.

Published in final edited form as: Angiogenesis. 2014 Oct; 17(4): 897–907. Published online 2014 Jul 2. doi: 10.1007/s10456-014-9437-2

PMCID:: PMC4177288

Abstract Article PDF–734K

Select item 535509519.

Differential regulation of cellular functions by the C-termini of transmembrane 4 L six family proteins in 2- or 3-dimensional environment

Jin-Gyu Cheong, Dae-Geun Song, Haeng Eun Song, Fedor Berditchevski, Seo Hee Nam, Jae Woo Jung, Hye-Jin Kim, Ji Eon Kim, Somi Kim, Jihye Ryu, Chang Yun Cho, Kyung-Min Lee, Jung Weon Lee

Oncotarget. 2017 Feb 21; 8(8): 13277–13292. Published online 2017 Jan 25. doi: 10.18632/oncotarget.14809