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Select item 110720081.

Artificial induction of circadian rhythm by combining exogenous BMAL1 expression and polycomb repressive complex 2 inhibition in human induced pluripotent stem cells

Hitomi Kaneko, Taku Kaitsuka, Kazuhito Tomizawa

Cell Mol Life Sci. 2023 Aug; 80(8): 200. Published online 2023 Jul 8. doi: 10.1007/s00018-023-04847-z

PMCID:: PMC11072008

Abstract Article PDF–2.5M

Select item 103823062.

Association of BMAL1 clock gene polymorphisms with fasting glucose in children

Yi-De Yang, Yuan Zeng, Jian Li, Jun-Hua Zhou, Quan-Yuan He, Chan-Juan Zheng, Christoph Reichetzeder, Bernhard K. Krämer, Berthold Hocher

Pediatr Res. 2023; 94(2): 653–659. Published online 2023 Feb 2. doi: 10.1038/s41390-023-02467-8

PMCID:: PMC10382306

Abstract Article PDF–908K

Select item 102731163.

Is BMAL1 Just One Song Impacting the Circadian Dance of Lung Injury?

Nancy H. Stewart, Isaac Kirubakaran Sundar

Am J Respir Crit Care Med. 2023 Jun 15; 207(12): 1642. Published online 2023 Feb 2. doi: 10.1164/rccm.202212-2311LE

PMCID:: PMC10273116

Article PDF–494K

Select item 98683884.

Bmal1 and Gut-lung axis in SARS-CoV-2 infection: New insight into the effects of melatonin on COVID-19 patients?

Mohammad Rafi Khezri, Reza Varzandeh, Morteza Ghasemnejad-Berenji

Biomed Pharmacother. 2023 Aug; 164: 114291. Published online 2023 Jan 23. doi: 10.1016/j.biopha.2023.114291

PMCID:: PMC9868388

Abstract Article PDF–844K

Select item 98475955.

Melatonin upregulates BMAL1 to attenuate chronic sleep deprivation‐related cognitive impairment by alleviating oxidative stress

Yujie Hu, Jierong Yin, Guoshuai Yang

Brain Behav. 2023 Jan; 13(1): e2836. Published online 2022 Dec 23. doi: 10.1002/brb3.2836

PMCID:: PMC9847595

Abstract Article PDF–974K

Select item 96828056.

Circadian clock gene Clock-Bmal1 regulates cellular senescence in Chronic obstructive pulmonary disease

Lingling Li, Min Zhang, Chunyang Zhao, Yusheng Cheng, Chuanmei Liu, Minhua Shi

BMC Pulm Med. 2022; 22: 435. Published online 2022 Nov 22. doi: 10.1186/s12890-022-02237-y

PMCID:: PMC9682805

Abstract Article PDF–5.5M

Select item 87439057.

Downregulation of Arntl mRNA Expression in Women with Hypertension: A Case-Control Study

Zhengmei Fang, Lijun Zhu, Yuelong Jin, Yan Chen, Weiwei Chang, Yingshui Yao

Kidney Blood Press Res. 2021 Dec; 46(6): 741–748. Published online 2021 Sep 3. doi: 10.1159/000518669

PMCID:: PMC8743905

Abstract Article

Select item 84435368.

The circadian clock component BMAL1 regulates SARS-CoV-2 entry and replication in lung epithelial cells

Xiaodong Zhuang, Senko Tsukuda, Florian Wrensch, Peter A.C. Wing, Mirjam Schilling, James M. Harris, Helene Borrmann, Sophie B. Morgan, Jennifer L. Cane, Laurent Mailly, Nazia Thakur, Carina Conceicao, Harshmeena Sanghani, Laura Heydmann, Charlotte Bach, Anna Ashton, Steven Walsh, Tiong Kit Tan, Lisa Schimanski, Kuan-Ying A. Huang, Catherine Schuster, Koichi Watashi, Timothy S.C. Hinks, Aarti Jagannath, Sridhar R. Vausdevan, Dalan Bailey, Thomas F. Baumert, Jane A. McKeating

iScience. 2021 Oct 22; 24(10): 103144. Published online 2021 Sep 16. doi: 10.1016/j.isci.2021.103144

PMCID:: PMC8443536

Abstract Article PDF–3.0M

Select item 81570269.

BMAL1 Knockdown Leans Epithelial–Mesenchymal Balance toward Epithelial Properties and Decreases the Chemoresistance of Colon Carcinoma Cells

Yuan Zhang, Aurore Devocelle, Christophe Desterke, Lucas Eduardo Botelho de Souza, Éva Hadadi, Hervé Acloque, Adlen Foudi, Yao Xiang, Annabelle Ballesta, Yunhua Chang, Julien Giron-Michel

Int J Mol Sci. 2021 May; 22(10): 5247. Published online 2021 May 16. doi: 10.3390/ijms22105247

PMCID:: PMC8157026

Abstract Article PDF–3.7M

Select item 806249610.

Circadian clock dysfunction in human omental fat links obesity to metabolic inflammation

Eleonore Maury, Benoit Navez, Sonia M. Brichard

Nat Commun. 2021; 12: 2388. Published online 2021 Apr 22. doi: 10.1038/s41467-021-22571-9

PMCID:: PMC8062496

Abstract Article PDF–2.7M

Select item 795511811.

Circadian control of hepatitis B virus replication

Xiaodong Zhuang, Donall Forde, Senko Tsukuda, Valentina D’Arienzo, Laurent Mailly, James M. Harris, Peter A. C. Wing, Helene Borrmann, Mirjam Schilling, Andrea Magri, Claudia Orbegozo Rubio, Robert J. Maidstone, Mudassar Iqbal, Miguel Garzon, Rosalba Minisini, Mario Pirisi, Sam Butterworth, Peter Balfe, David W. Ray, Koichi Watashi, Thomas F. Baumert, Jane A. McKeating

Nat Commun. 2021; 12: 1658. Published online 2021 Mar 12. doi: 10.1038/s41467-021-21821-0

PMCID:: PMC7955118

Abstract Article PDF–3.1M

Select item 779590812.

Proinflammatory Cytokines Perturb Mouse and Human Pancreatic Islet Circadian Rhythmicity and Induce Uncoordinated β-Cell Clock Gene Expression via Nitric Oxide, Lysine Deacetylases, and Immunoproteasomal Activity

Phillip Alexander Keller Andersen, Volodymyr Petrenko, Peter Horskjær Rose, Melissa Koomen, Nico Fischer, Seyed Mojtaba Ghiasi, Tina Dahlby, Charna Dibner, Thomas Mandrup-Poulsen

Int J Mol Sci. 2021 Jan; 22(1): 83. Published online 2020 Dec 23. doi: 10.3390/ijms22010083

PMCID:: PMC7795908

Abstract Article PDF–5.5M

Select item 722696613.

Extracellular Acidosis Promotes Metastatic Potency via Decrease of the BMAL1 Circadian Clock Gene in Breast Cancer

Yong-Jin Kwon, Eun-Bi Seo, Sun-Ho Kwon, Song-Hee Lee, Seul-Ki Kim, Sang Ki Park, Kyungjin Kim, SaeGwang Park, In-Chul Park, Jong-Wan Park, Sang-Kyu Ye

Cells. 2020 Apr; 9(4): 989. Published online 2020 Apr 16. doi: 10.3390/cells9040989

PMCID:: PMC7226966

Abstract Article PDF–4.3M

Select item 715628214.

BMAL1 coordinates energy metabolism and differentiation of pluripotent stem cells

Cristina Ameneiro, Tiago Moreira, Alejandro Fuentes-Iglesias, Alba Coego, Vera Garcia-Outeiral, Adriana Escudero, Daniel Torrecilla, Sonia Mulero-Navarro, Jose Maria Carvajal-Gonzalez, Diana Guallar, Miguel Fidalgo

Life Sci Alliance. 2020 May; 3(5): e201900534. Published online 2020 Apr 13. doi: 10.26508/lsa.201900534

PMCID:: PMC7156282

Abstract Article PDF–2.7M

Select item 665654615.

Clockophagy is a novel selective autophagy process favoring ferroptosis

Minghua Yang, Pan Chen, Jiao Liu, Shan Zhu, Guido Kroemer, Daniel J. Klionsky, Michael T. Lotze, Herbert J. Zeh, Rui Kang, Daolin Tang

Sci Adv. 2019 Jul; 5(7): eaaw2238. Published online 2019 Jul 24. doi: 10.1126/sciadv.aaw2238

PMCID:: PMC6656546

Abstract Article PDF–860K

Select item 628387716.

A splice variant of human Bmal1 acts as a negative regulator of the molecular circadian clock

Jiwon Lee, Eonyoung Park, Ga Hye Kim, Ilmin Kwon, Kyungjin Kim

Exp Mol Med. 2018 Dec; 50(12): 159. Published online 2018 Dec 6. doi: 10.1038/s12276-018-0187-x

PMCID:: PMC6283877

Abstract Article PDF–2.2M

Select item 620778317.

Opposite Carcinogenic Effects of Circadian Clock Gene BMAL1

Tuba Korkmaz, Fatih Aygenli, Handan Emisoglu, Gozde Ozcelik, Asena Canturk, Secil Yilmaz, Nuri Ozturk

Sci Rep. 2018; 8: 16023. Published online 2018 Oct 30. doi: 10.1038/s41598-018-34433-4

PMCID:: PMC6207783

Abstract Article PDF–1.5M

Select item 617379418.

Variation in cell associated unspliced HIV RNA on antiretroviral therapy is associated with the circadian regulator BMAL-1

Christina C CHANG, Vivek NARANBHAI, Jared STERN, Michael ROCHE, Ashanti DANTANARAYANA, Ruian KE, Surekha TENNAKOON, Ajantha SOLOMON, Rebecca HOH, Wendy HARTOGENSIS, Frederick M HECHT, Ken SIKARIS, David J PRICE, Julian H ELLIOTT, Steven G DEEKS, Melissa CHURCHILL, Paul U CAMERON, Nicolas HENGARTNER, Alan S. PERELSON, Sharon R LEWIN

AIDS. Author manuscript; available in PMC 2019 Sep 24.

Published in final edited form as: AIDS. 2018 Sep 24; 32(15): 2119–2128. doi: 10.1097/QAD.0000000000001937

Correction in:: AIDS. 2018 Nov 13; 32(17): 2643–2647.

PMCID:: PMC6173794

Abstract Article PDF–1.0M

Select item 578592919.

Circadian alterations during early stages of Alzheimer’s disease are associated with aberrant cycles of DNA methylation in BMAL1

Peter Cronin, Michael J. McCarthy, Andrew S.P. Lim, David P. Salmon, Douglas Galasko, Eliezer Masliah, Philip L. De Jager, David A. Bennett, Paula Desplats

Alzheimers Dement. Author manuscript; available in PMC 2018 Jun 1.

Published in final edited form as: Alzheimers Dement. 2017 Jun; 13(6): 689–700. Published online 2016 Nov 22. doi: 10.1016/j.jalz.2016.10.003

PMCID:: PMC5785929

Abstract Article PDF–1.7M

Select item 543793820.

Epigenetic regulation of the circadian clock: role of 5-aza-2′-deoxycytidine

Tatsunosuke Tomita, Ryoji Kurita, Yoshiaki Onishi

Biosci Rep. 2017 Jun 30; 37(3): BSR20170053. Prepublished online 2017 May 9. Published online 2017 May 19. doi: 10.1042/BSR20170053

PMCID:: PMC5437938

Abstract Article PDF–675K

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PMC Links for Gene (Select 406) (149)
PMC
G protein-coupled receptor kinase 4 isoform X18 [Homo sapiens]
G protein-coupled receptor kinase 4 isoform X18 [Homo sapiens]
gi|2462596755|ref|XP_054205787.1|

Protein
PREDICTED: Homo sapiens G protein-coupled receptor kinase 4 (GRK4), transcript v...
PREDICTED: Homo sapiens G protein-coupled receptor kinase 4 (GRK4), transcript variant X10, mRNA
gi|2217350331|ref|XM_011513453.3|

Nucleotide
PREDICTED: Homo sapiens G protein-coupled receptor kinase 4 (GRK4), transcript v...
PREDICTED: Homo sapiens G protein-coupled receptor kinase 4 (GRK4), transcript variant X24, mRNA
gi|2217350349|ref|XM_047450128.1|

Nucleotide
basic helix-loop-helix ARNT-like protein 1 isoform g [Homo sapiens]
basic helix-loop-helix ARNT-like protein 1 isoform g [Homo sapiens]
gi|1198817734|ref|NP_001338734.1|

Protein

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