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Select item 104173021.

The mRNA and protein levels of the glycolytic enzymes lactate dehydrogenase A (LDHA) and phosphofructokinase platelet (PFKP) are good predictors of survival time, recurrence, and risk of death in cervical cancer patients

Verónica Bolaños‐Suárez, Ana Alfaro, Ana María Espinosa, Ingrid Medina‐Martínez, Eligia Juárez, Nicolás Villegas‐Sepúlveda, Marco Gudiño‐Zayas, América Gutiérrez‐Castro, Edgar Román‐Bassaure, María Eugenia Salinas‐Nieves, Sergio Bruno‐Muñoz, Carlos Aranda, Oscar Flores‐Herrera, Jaime Berumen

Cancer Med. 2023 Jul; 12(14): 15632–15649. Published online 2023 Jun 16. doi: 10.1002/cam4.6123

PMCID:: PMC10417302

Abstract Article PDF–12M

Select item 98918652.

Circular RNA, circular RARS, promotes aerobic glycolysis of non‐small‐cell lung cancer by binding with LDHA

Haoran Li, Qi Huang, Haifa Guo, Xiuyuan Chen, Xiao Li, Mantang Qiu

Thorac Cancer. 2023 Feb; 14(4): 389–398. Published online 2023 Jan 11. doi: 10.1111/1759-7714.14758

PMCID:: PMC9891865

Abstract Article PDF–6.9M

Select item 97850693.

Effect of LDHA Inhibition on TNF-α-Induced Cell Migration in Esophageal Cancers

Agata Forkasiewicz, Wojciech Stach, Jaroslaw Wierzbicki, Kamilla Stach, Renata Tabola, Anita Hryniewicz-Jankowska, Katarzyna Augoff

Int J Mol Sci. 2022 Dec; 23(24): 16062. Published online 2022 Dec 16. doi: 10.3390/ijms232416062

PMCID:: PMC9785069

Abstract Article PDF–4.6M

Select item 96016874.

Clinical, Biochemical, and Molecular Characterization of Two Families with Novel Mutations in the LDHA Gene (GSD XI)

Pablo Serrano-Lorenzo, María Rabasa, Jesús Esteban, Irene Hidalgo Mayoral, Cristina Domínguez-González, Agustín Blanco-Echevarría, Rocío Garrido-Moraga, Alejandro Lucia, Alberto Blázquez, Juan C. Rubio, Carmen Palma-Milla, Joaquín Arenas, Miguel A. Martín

Genes (Basel) 2022 Oct; 13(10): 1835. Published online 2022 Oct 11. doi: 10.3390/genes13101835

PMCID:: PMC9601687

Abstract Article PDF–1.6M

Select item 93098565.

High Expression of Lactate Dehydrogenase A is a Potential Promoter of Malignant Behaviour in Extramammary Paget’s Disease

Kohei OGAWA, Keiji SHIMADA, Toshihiro TAKAI, Yasuhiro MITSUI, Masamitsu KUWAHARA, Hideo ASADA

Acta Derm Venereol. 2021; 101(1): 1499. Published online 2021 Jan 25. doi: 10.2340/00015555-3744

PMCID:: PMC9309856

Article PDF–1.1M

Select item 92542456.

N⁶-methyladenosine-mediated LDHA induction potentiates chemoresistance of colorectal cancer cells through metabolic reprogramming

Kun Zhang, Tao Zhang, Yuhan Yang, Wenling Tu, Hongbin Huang, Yujun Wang, Yuzhuo Chen, Kejian Pan, Zhuojia Chen

Theranostics. 2022; 12(10): 4802–4817. Published online 2022 Jun 13. doi: 10.7150/thno.73746

PMCID:: PMC9254245

Abstract Article PDF–3.2M

Select item 89821367.

Clinical Significance and Prognostic Value of Lactate Dehydrogenase Expression in Cervical Cancer

Yuping Ye, Min Chen, Xinyan Chen, Jingyu Xiao, Lin Liao, Faquan Lin

Genet Test Mol Biomarkers. March 2022; 26(3): 107–117. Published online 2022 Mar 29. doi: 10.1089/gtmb.2021.0006

PMCID:: PMC8982136

Abstract Article PDF–970K

Select item 88926078.

Inhibition of LDHA suppresses cell proliferation and increases mitochondrial apoptosis via the JNK signaling pathway in cervical cancer cells

Wenjing Zhang, Cui Wang, Xiaomei Hu, Yanzhen Lian, Caili Ding, Liang Ming

Oncol Rep. 2022 Apr; 47(4): 77. Published online 2022 Feb 18. doi: 10.3892/or.2022.8288

PMCID:: PMC8892607

Abstract Article PDF–4.2M

Select item 84576129.

Prognostic value of neutrophil-to-lymphocyte ratio, lactate dehydrogenase, D-dimer, and computed tomography score in patients with coronavirus disease 2019

Yu-Qing Cai, Xiao-Bin Zhang, Hui-Qing Zeng, Xiao-Jie Wei, Lan Hu, Zhen-Yu Zhang, Quan Ming, Qiu-Ping Peng, Li-Da Chen

Aging (Albany NY) 2021 Sep 15; 13(17): 20896–20905. Published online 2021 Sep 8. doi: 10.18632/aging.203501

PMCID:: PMC8457612

Abstract Article PDF–546K

Select item 836449910.

LDHA is enriched in human islet alpha cells and upregulated in type 2 diabetes

Paulina Karen Mendoza Sanchez, Mona Khazaei, Eva Gatineau, Shirin Geravandi, Blaz Lupse, Huan Liu, Ralf Dringen, Anne Wojtusciszyn, Patrick Gilon, Kathrin Maedler, Amin Ardestani

Biochem Biophys Res Commun. Author manuscript; available in PMC 2022 Sep 3.

Published in final edited form as: Biochem Biophys Res Commun. 2021 Sep 3; 568: 158–166. Published online 2021 Jul 1. doi: 10.1016/j.bbrc.2021.06.065

PMCID:: PMC8364499

Abstract Article PDF–1.1M

Select item 835389811.

LDH‐A negatively regulates dMMR in colorectal cancer

Yongjie Zhang, Juan Li, Bo Wang, Ting Chen, Yun Chen, Wen Ma

Cancer Sci. 2021 Aug; 112(8): 3050–3063. Published online 2021 Jul 4. doi: 10.1111/cas.15020

PMCID:: PMC8353898

Abstract Article PDF–1.9M

Select item 828128512.

Hypoxia-induced lactate dehydrogenase A protects cells from apoptosis in endometriosis

Jinyan Zheng, Yongdong Dai, Xiang Lin, Qianmeng Huang, Libing Shi, Xiaoying Jin, Na Liu, Feng Zhou, Songying Zhang

Mol Med Rep. 2021 Sep; 24(3): 637. Published online 2021 Jul 6. doi: 10.3892/mmr.2021.12276

PMCID:: PMC8281285

Abstract Article PDF–4.2M

Select item 823892013.

Functional inhibition of lactate dehydrogenase suppresses pancreatic adenocarcinoma progression

Chien‐shan Cheng, Hor‐Yue Tan, Ning Wang, Lianyu Chen, Zhiqiang Meng, Zhen Chen, Yibin Feng

Clin Transl Med. 2021 Jun; 11(6): e467. Published online 2021 Jun 28. doi: 10.1002/ctm2.467

PMCID:: PMC8238920

Abstract Article PDF–18M

Select item 793785214.

Lactate Dehydrogenase A as a Potential New Biomarker for Thyroid Cancer

Eun Jeong Ban, Daham Kim, Jin Kyong Kim, Sang-Wook Kang, Jandee Lee, Jong Ju Jeong, Kee-Hyun Nam, Woong Youn Chung, Kunhong Kim

Endocrinol Metab (Seoul) 2021 Feb; 36(1): 96–105. Published online 2021 Feb 24. doi: 10.3803/EnM.2020.819

PMCID:: PMC7937852

Abstract Article PDF–759K

Select item 639111215.

Stress-induced epinephrine enhances lactate dehydrogenase A and promotes breast cancer stem-like cells

Bai Cui, Yuanyuan Luo, Pengfei Tian, Fei Peng, Jinxin Lu, Yongliang Yang, Qitong Su, Bing Liu, Jiachuan Yu, Xi Luo, Liu Yin, Wei Cheng, Fan An, Bin He, Dapeng Liang, Sijin Wu, Peng Chu, Luyao Song, Xinyu Liu, Huandong Luo, Jie Xu, Yujia Pan, Yang Wang, Dangsheng Li, Peng Huang, Qingkai Yang, Lingqiang Zhang, Binhua P. Zhou, Suling Liu, Guowang Xu, Eric W.-F. Lam, Keith W. Kelley, Quentin Liu

J Clin Invest. 2019 Mar 1; 129(3): 1030–1046. Published online 2019 Jan 28. doi: 10.1172/JCI121685