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Items: 1 to 20 of 61

1.
An in-vivo microfluidic assay reveals cardiac toxicity of heavy metals and the protective effect of metal responsive transcription factor (MTF-1) in Drosophila model
Alireza Zabihihesari, Shahrzad Parand, Alistair B. Coulthard, Alexander Molnar, Arthur J. Hilliker, Pouya Rezai
3 Biotech. 2022 Oct; 12(10): 279. Published online 2022 Sep 15. doi: 10.1007/s13205-022-03336-7
PMCID:
PMC9478020
AbstractArticlePDF–3.3M
2.
Gawky modulates MTF-1-mediated transcription activation and metal discrimination
Ruirui Jia, Zhenxing Song, Jiamei Lin, Zhengguo Li, Ge Shan, Chuan Huang
Nucleic Acids Res. 2021 Jun 21; 49(11): 6296–6314. Published online 2021 Jun 9. doi: 10.1093/nar/gkab474
PMCID:
PMC8216474
AbstractArticlePDF–2.2M
3.
Mottled Mice and Non-Mammalian Models of Menkes Disease
Małgorzata Lenartowicz, Wojciech Krzeptowski, Paweł Lipiński, Paweł Grzmil, Rafał Starzyński, Olga Pierzchała, Lisbeth Birk Møller
Front Mol Neurosci. 2015; 8: 72. Published online 2015 Dec 18. doi: 10.3389/fnmol.2015.00072
PMCID:
PMC4684000
AbstractArticlePDF–2.0M
4.
Copper sensing function of Drosophila metal-responsive transcription factor-1 is mediated by a tetranuclear Cu(I) cluster
Xiaohua Chen, Haiqing Hua, Kuppusamy Balamurugan, Xiangming Kong, Limei Zhang, Graham N. George, Oleg Georgiev, Walter Schaffner, David P. Giedroc
Nucleic Acids Res. 2008 May; 36(9): 3128–3138. Published online 2008 Apr 13. doi: 10.1093/nar/gkn103
PMCID:
PMC2396432
AbstractArticlePDF–624K
5.
Efficient metal-specific transcription activation by Drosophila MTF-1 requires conserved cysteine residues in the carboxy-terminal domain
Sharon K. Marr, Katie L. Pennington, Michael T. Marr
Biochim Biophys Acta. Author manuscript; available in PMC 2013 Aug 1.
Published in final edited form as: Biochim Biophys Acta. 2012 Aug; 1819(8): 902–912. Published online 2012 Mar 28. doi: 10.1016/j.bbagrm.2012.03.005
PMCID:
PMC3378919
AbstractArticlePDF–3.3M
6.
Single nucleotide in the MTF-1 binding site can determine metal-specific transcription activation
Hillel I. Sims, Gung-Wei Chirn, Michael T. Marr, II
Proc Natl Acad Sci U S A. 2012 Oct 9; 109(41): 16516–16521. Published online 2012 Sep 24. doi: 10.1073/pnas.1207737109
PMCID:
PMC3478646
AbstractArticlePDF–985K
7.
The parkin Mutant Phenotype in the Fly Is Largely Rescued by Metal-Responsive Transcription Factor (MTF-1)
Nidhi Saini, Oleg Georgiev, Walter Schaffner
Mol Cell Biol. 2011 May; 31(10): 2151–2161. doi: 10.1128/MCB.05207-11
PMCID:
PMC3133352
AbstractArticlePDF–2.5M
8.
Knockout of ‘metal-responsive transcription factor’ MTF-1 in Drosophila by homologous recombination reveals its central role in heavy metal homeostasis
Dieter Egli, Anand Selvaraj, Hasmik Yepiskoposyan, Bo Zhang, Ernst Hafen, Oleg Georgiev, Walter Schaffner
EMBO J. 2003 Jan 2; 22(1): 100–108. doi: 10.1093/emboj/cdg012
PMCID:
PMC140060
AbstractArticlePDF–322K
9.
The Drosophila Homolog of Mammalian Zinc Finger Factor MTF-1 Activates Transcription in Response to Heavy Metals
Bo Zhang, Dieter Egli, Oleg Georgiev, Walter Schaffner
Mol Cell Biol. 2001 Jul; 21(14): 4505–4514. doi: 10.1128/MCB.21.14.4505-4514.2001
PMCID:
PMC87110
AbstractArticlePDF–473K
10.
Copper homeostasis in Drosophila by complex interplay of import, storage and behavioral avoidance
Kuppusamy Balamurugan, Dieter Egli, Haiqing Hua, Rama Rajaram, Gerhard Seisenbacher, Oleg Georgiev, Walter Schaffner
EMBO J. 2007 Feb 21; 26(4): 1035–1044. Published online 2007 Feb 8. doi: 10.1038/sj.emboj.7601543
PMCID:
PMC1852831
AbstractArticlePDF–460K
11.
Diverse families of transposable elements affect the transcriptional regulation of stress-response genes in Drosophila melanogaster
José Luis Villanueva-Cañas, Vivien Horvath, Laura Aguilera, Josefa González
Nucleic Acids Res. 2019 Jul 26; 47(13): 6842–6857. Published online 2019 Jun 8. doi: 10.1093/nar/gkz490
PMCID:
PMC6649756
AbstractArticlePDF–2.5M
12.
A Cell Density-Dependent Reporter in the Drosophila S2 Cells
Matthew L. Romine, Mo Li, Kevin Jiayang Liu, Sapna K. Patel, Julie G. Nelson, Ping Shen, Haini N. Cai
Sci Rep. 2019; 9: 11868. Published online 2019 Aug 14. doi: 10.1038/s41598-019-47652-0
PMCID:
PMC6694118
AbstractArticlePDF–2.5M
13.
RNA-binding profiles of Drosophila CPEB proteins Orb and Orb2
Barbara Krystyna Stepien, Cornelia Oppitz, Daniel Gerlach, Ugur Dag, Maria Novatchkova, Sebastian Krüttner, Alexander Stark, Krystyna Keleman
Proc Natl Acad Sci U S A. 2016 Nov 8; 113(45): E7030–E7038. Published online 2016 Oct 24. doi: 10.1073/pnas.1603715113
PMCID:
PMC5111685
AbstractArticlePDF–1.3M
14.
Dumpy-30 family members as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila
Alla Vardanyan, Lilit Atanesyan, Dieter Egli, Sunil Jayaramaiah Raja, Monica Steinmann-Zwicky, Renate Renkawitz-Pohl, Oleg Georgiev, Walter Schaffner
BMC Dev Biol. 2008; 8: 68. Published online 2008 Jun 27. doi: 10.1186/1471-213X-8-68
PMCID:
PMC2478662
AbstractArticlePDF–1.7M
15.
Metal-responsive transcription factor (MTF-1) handles both extremes, copper load and copper starvation, by activating different genes
Anand Selvaraj, Kuppusamy Balamurugan, Hasmik Yepiskoposyan, Hao Zhou, Dieter Egli, Oleg Georgiev, Dennis J. Thiele, Walter Schaffner
Genes Dev. 2005 Apr 15; 19(8): 891–896. doi: 10.1101/gad.1301805
PMCID:
PMC1080128
AbstractArticlePDF–435K
16.
Copper homoeostasis in Drosophila melanogaster S2 cells
Adam Southon, Richard Burke, Melanie Norgate, Philip Batterham, James Camakaris
Biochem J. 2004 Oct 15; 383(Pt 2): 303–309. Prepublished online 2004 Jul 7. Published online 2004 Oct 8. doi: 10.1042/BJ20040745
PMCID:
PMC1134071
AbstractArticlePDF–132K
17.
A Family Knockout of All Four Drosophila Metallothioneins Reveals a Central Role in Copper Homeostasis and Detoxification
Dieter Egli, Hasmik Yepiskoposyan, Anand Selvaraj, Kuppusamy Balamurugan, Rama Rajaram, Andreas Simons, Gerd Multhaup, Simone Mettler, Alla Vardanyan, Oleg Georgiev, Walter Schaffner
Mol Cell Biol. 2006 Mar; 26(6): 2286–2296. doi: 10.1128/MCB.26.6.2286-2296.2006
PMCID:
PMC1430275
AbstractArticlePDF–623K
18.
Genetic Screen for Regulators of Lymph Gland Homeostasis and Hemocyte Maturation in Drosophila
Kai Li Tan, Siow Chong Goh, Svetlana Minakhina
G3 (Bethesda) 2012 Mar; 2(3): 393–405. Published online 2012 Mar 1. doi: 10.1534/g3.111.001693
PMCID:
PMC3291509
AbstractArticlePDF–3.3M
19.
Genome-wide identification of hypoxia-induced enhancer regions
Nick Kamps-Hughes, Jessica L. Preston, Melissa A. Randel, Eric A. Johnson
PeerJ. 2015; 3: e1527. Published online 2015 Dec 21. doi: 10.7717/peerj.1527
PMCID:
PMC4690393
AbstractArticlePDF–4.8M
20.
Genome-Wide Association Analysis of Tolerance to Methylmercury Toxicity in Drosophila Implicates Myogenic and Neuromuscular Developmental Pathways
Sara L. Montgomery, Daria Vorojeikina, Wen Huang, Trudy F. C. Mackay, Robert R. H. Anholt, Matthew D. Rand
PLoS One. 2014; 9(10): e110375. Published online 2014 Oct 31. doi: 10.1371/journal.pone.0110375
PMCID:
PMC4215868
AbstractArticlePDF–1.5M

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