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Select item 100369501.

Scleral Proteome in Noninfectious Scleritis Unravels Upregulation of Filaggrin-2 and Signs of Neovascularization

Daphne P. C. Vergouwen, Josianne C. Ten Berge, Coskun Guzel, Thierry P. P. van den Bosch, Robert M. Verdijk, Aniki Rothova, Theo M. Luider, Marco W. J. Schreurs

Invest Ophthalmol Vis Sci. 2023 Mar; 64(3): 27. Published online 2023 Mar 17. doi: 10.1167/iovs.64.3.27

PMCID:: PMC10036950

Abstract Article PDF–1.5M

Select item 66901372.

Highlight article: Whole-exome sequencing indicates FLG2 variant associated with leg ulcers in Brazilian sickle cell anemia patients

Gabriela Queila de Carvalho-Siqueira, Galina Ananina, Bruno Batista de Souza, Murilo Guimarães Borges, Mirta Tomie Ito, Sueli Matilde da Silva-Costa, Igor de Farias Domingos, Diego Arruda Falcão, Iscia Lopes-Cendes, Marcos André Cavalcanti Bezerra, Aderson da Silva Araújo, Antônio Roberto Lucena-Araújo, Marilda de Souza Gonçalves, Sara Teresinha Olalla Saad, Fernando Ferreira Costa, Mônica Barbosa de Melo

Exp Biol Med (Maywood) 2019 Aug; 244(11): 932–939. Published online 2019 May 12. doi: 10.1177/1535370219849592

PMCID:: PMC6690137

Abstract Article PDF–423K

Select item 62335983.

Soluble fibrinogen-like protein 2 levels in patients with hepatitis B virus-related liver diseases

Hoang Van Tong, Nguyen Van Ba, Nghiem Xuan Hoan, Mai Thanh Binh, Dao Thanh Quyen, Ho Anh Son, Hoang Van Luong, Do Quyet, Christian G. Meyer, Le Huu Song, Nguyen Linh Toan, Thirumalaisamy P. Velavan

BMC Infect Dis. 2018; 18: 553. Published online 2018 Nov 12. doi: 10.1186/s12879-018-3473-2

PMCID:: PMC6233598

Abstract Article PDF–904K

Select item 46698144.

In a three-dimensional reconstructed human epidermis filaggrin-2 is essential for proper cornification

V Pendaries, M Le Lamer, L Cau, B Hansmann, J Malaisse, S Kezic, G Serre, M Simon

Cell Death Dis. 2015 Feb; 6(2): e1656. Published online 2015 Feb 19. doi: 10.1038/cddis.2015.29

PMCID:: PMC4669814

Abstract Article PDF–2.3M

Select item 45707135.

Skin-Derived C-Terminal Filaggrin-2 Fragments Are Pseudomonas aeruginosa-Directed Antimicrobials Targeting Bacterial Replication

Britta Hansmann, Jens-Michael Schröder, Ulrich Gerstel

PLoS Pathog. 2015 Sep; 11(9): e1005159. Published online 2015 Sep 15. doi: 10.1371/journal.ppat.1005159

PMCID:: PMC4570713

Abstract Article PDF–6.3M

Select item 39435646.

Filaggrin-2 variation is associated with more persistent atopic dermatitis in African Americans

David J. Margolis, Jayanta Gupta, Andrea J. Apter, Tapan Ganguly, Ole Hoffstad, Maryte Papadopoulos, Tim R. Rebbeck, Nandita Mitra

J Allergy Clin Immunol. Author manuscript; available in PMC 2015 Mar 1.

Published in final edited form as: J Allergy Clin Immunol. 2014 Mar; 133(3): 784–789. Published online 2013 Nov 1. doi: 10.1016/j.jaci.2013.09.015

PMCID:: PMC3943564

Abstract Article PDF–585K

Select item 92509407.

Uncommon variants in FLG2 and TCHHL1 are associated with remission of atopic dermatitis in a large longitudinal US cohort

Ronald Berna, Nandita Mitra, Ole Hoffstad, Bradley Wubbenhorst, Katherine L. Nathanson, David J. Margolis

Arch Dermatol Res. Author manuscript; available in PMC 2023 Dec 1.

Published in final edited form as: Arch Dermatol Res. 2022 Dec; 314(10): 953–959. Published online 2022 Jan 4. doi: 10.1007/s00403-021-02319-7

PMCID:: PMC9250940

Abstract Article PDF–169K

Select item 60563318.

Filaggrin 2 Deficiency Results in Abnormal Cell-Cell Adhesion in the Cornified Cell Layers and Causes Peeling Skin Syndrome Type A

Janan Mohamad, Ofer Sarig, Lisa M. Godsel, Alon Peled, Natalia Malchin, Ron Bochner, Dan Vodo, Tom Rabinowitz, Mor Pavlovsky, Shahar Taiber, Maya Fried, Marina Eskin-Schwartz, Siwar Assi, Noam Shomron, Jouni Uitto, Jennifer L. Koetsier, Reuven Bergman, Kathleen J. Green, Eli Sprecher

J Invest Dermatol. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: J Invest Dermatol. 2018 Aug; 138(8): 1736–1743. Published online 2018 Jun 27. doi: 10.1016/j.jid.2018.04.032

PMCID:: PMC6056331

Abstract Article PDF–1.2M

Select item 26681859.

Molecular Identification and Expression Analysis of Filaggrin-2, a Member of the S100 Fused-Type Protein Family

Zhihong Wu, Britta Hansmann, Ulf Meyer-Hoffert, Regine Gläser, Jens-Michael Schröder

PLoS One. 2009; 4(4): e5227. Published online 2009 Apr 22. doi: 10.1371/journal.pone.0005227

PMCID:: PMC2668185

Abstract Article PDF–983K

Select item 724178510.

Filaggrin and filaggrin 2 processing are linked together through skin aspartic acid protease activation

Mark Donovan, Mélanie Salamito, Agnès Thomas-Collignon, Lucie Simonetti, Stephanie Desbouis, Jean-Christophe Rain, Etienne Formstecher, Dominique Bernard

PLoS One. 2020; 15(5): e0232679. Published online 2020 May 21. doi: 10.1371/journal.pone.0232679

PMCID:: PMC7241785

Abstract Article PDF–1.4M

Select item 560562811.

GATA3 regulates FLG and FLG2 expression in human primary keratinocytes

Jana Zeitvogel, Neele Jokmin, Samira Rieker, Ilona Klug, Christina Brandenberger, Thomas Werfel

Sci Rep. 2017; 7: 11847. Published online 2017 Sep 19. doi: 10.1038/s41598-017-10252-x

PMCID:: PMC5605628

Abstract Article PDF–6.6M

Select item 312308912.

Deimination of Human Filaggrin-2 Promotes Its Proteolysis by Calpain 1

Chiung-Yueh Hsu, Julie Henry, Anne-Aurélie Raymond, Marie-Claire Méchin, Valérie Pendaries, Dany Nassar, Britta Hansmann, Stéfana Balica, Odile Burlet-Schiltz, Anne-Marie Schmitt, Hidenari Takahara, Carle Paul, Guy Serre, Michel Simon

J Biol Chem. 2011 Jul 1; 286(26): 23222–23233. Published online 2011 Apr 29. doi: 10.1074/jbc.M110.197400

PMCID:: PMC3123089

Abstract Article PDF–2.3M

Select item 811178813.

Kir2.1 Interaction with Stk38 Promotes Invasion and Metastasis of Human Gastric Cancer by Enhancing MEKK2–MEK1/2–ERK1/2 Signaling

Cheng-Dong Ji, Yan-Xia Wang, Dong-Fang Xiang, Qiang Liu, Zhi-Hua Zhou, Feng Qian, Lang Yang, Yong Ren, Wei Cui, Sen-Lin Xu, Xi-Long Zhao, Xia Zhang, Yan Wang, Peng Zhang, Ji-Ming Wang, You-Hong Cui, Xiu-Wu Bian

Cancer Res. Author manuscript; available in PMC 2021 May 11.

Published in final edited form as: Cancer Res. 2018 Jun 1; 78(11): 3041–3053. Published online 2018 Mar 16. doi: 10.1158/0008-5472.CAN-17-3776

PMCID:: PMC8111788

Abstract Article PDF–2.1M

Select item 288344014.

FCHo Proteins are Nucleators of Clathrin-Mediated Endocytosis

William Mike Henne, Emmanuel Boucrot, Michael Meinecke, Emma Evergren, Yvonne Vallis, Rohit Mittal, Harvey T. McMahon

Science. Author manuscript; available in PMC 2010 Dec 7.

Published in final edited form as: Science. 2010 Jun 4; 328(5983): 1281–1284. Published online 2010 May 6. doi: 10.1126/science.1188462

PMCID:: PMC2883440

Abstract Article PDF–1.7M

Select item 605336415.

Armadillo repeat containing 12 promotes neuroblastoma progression through interaction with retinoblastoma binding protein 4

Dan Li, Huajie Song, Hong Mei, Erhu Fang, Xiaojing Wang, Feng Yang, Huanhuan Li, Yajun Chen, Kai Huang, Liduan Zheng, Qiangsong Tong

Nat Commun. 2018; 9: 2829. Published online 2018 Jul 19. doi: 10.1038/s41467-018-05286-2

PMCID:: PMC6053364

Abstract Article PDF–4.3M

Select item 952752016.

EGFR suppresses p53 function by promoting p53 binding to DNA-PKcs: a noncanonical regulatory axis between EGFR and wild-type p53 in glioblastoma

Jie Ding, Xiaolong Li, Sabbir Khan, Chen Zhang, Feng Gao, Shayak Sen, Amanda R Wasylishen, Yang Zhao, Guillermina Lozano, Dimpy Koul, W K Alfred Yung

Neuro Oncol. 2022 Oct; 24(10): 1712–1725. Published online 2022 Apr 26. doi: 10.1093/neuonc/noac105

PMCID:: PMC9527520

Abstract Article PDF–12M

Select item 714045017.

Hypermethylation of UCHL1 Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing Degradation of Cortactin (CTTN)

Yin Zhao, Yuan Lei, Shi-Wei He, Ying-Qin Li, Ya-Qin Wang, Xiao-Hong Hong, Ye-Lin Liang, Jun-Yan Li, Yang Chen, Wei-Jie Luo, Pan-Pan Zhang, Xiao-Jing Yang, Qing-Mei He, Jun Ma, Na Liu, Ling-Long Tang

Cells. 2020 Mar; 9(3): 559. Published online 2020 Feb 27. doi: 10.3390/cells9030559

Correction in:: Cells. 2024 May; 13(10): 816.

PMCID:: PMC7140450

Abstract Article PDF–4.3M

Select item 983165418.

Sleeve gastrectomy improves lipid dysmetabolism by downregulating the USP20-HSPA2 axis in diet-induced obese mice

Wenjie Zhang, Bowen Shi, Shirui Li, Zenglin Liu, Songhan Li, Shuohui Dong, Yugang Cheng, Jiankang Zhu, Guangyong Zhang, Mingwei Zhong

Front Endocrinol (Lausanne) 2022; 13: 1041027. Published online 2022 Dec 27. doi: 10.3389/fendo.2022.1041027

PMCID:: PMC9831654

Abstract Article PDF–25M

Select item 602600519.

Destabilizing NEK2 overcomes resistance to proteasome inhibition in multiple myeloma

Reinaldo Franqui-Machin, Mu Hao, Hua Bai, Zhimin Gu, Xin Zhan, Hasem Habelhah, Yogesh Jethava, Lugui Qiu, Ivana Frech, Guido Tricot, Fenghuang Zhan

J Clin Invest. 2018 Jul 2; 128(7): 2877–2893. Published online 2018 Jun 4. doi: 10.1172/JCI98765

PMCID:: PMC6026005

Abstract Article PDF–13M

Select item 949923820.

SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein

Marius Walter, Irene P. Chen, Albert Vallejo-Gracia, Ik-Jung Kim, Olga Bielska, Victor L. Lam, Jennifer M. Hayashi, Andrew Cruz, Samah Shah, Frank W. Soveg, John D. Gross, Nevan J. Krogan, Keith R. Jerome, Birgit Schilling, Melanie Ott, Eric Verdin

PLoS Pathog. 2022 Sep; 18(9): e1010811. Published online 2022 Sep 12. doi: 10.1371/journal.ppat.1010811

PMCID:: PMC9499238

Abstract Article PDF–3.7M

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PMC Links for Gene (Select 388698) (70)
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PAS domain-containing methyl-accepting chemotaxis protein [Bordetella bronchisep...
PAS domain-containing methyl-accepting chemotaxis protein [Bordetella bronchiseptica]
gi|489908444|ref|WP_003811863.1|

Protein
RecName: Full=Renal cancer differentiation gene 1 protein
RecName: Full=Renal cancer differentiation gene 1 protein
gi|74740214|sp|Q504U0.1|CD046_HUMAN

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