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Select item 112384871.

MicroRNA-21 modulates brown adipose tissue adipogenesis and thermogenesis in a mouse model of polycystic ovary syndrome

Samar Rezq, Alexandra M. Huffman, Jelina Basnet, Amira E. Alsemeh, Jussara M. do Carmo, Licy L. Yanes Cardozo, Damian G. Romero

Biol Sex Differ. 2024; 15: 53. Published online 2024 Jul 10. doi: 10.1186/s13293-024-00630-2

PMCID:: PMC11238487

Abstract Article PDF–2.7M

Select item 109962532.

The mechanisms of MicroRNA 21 in premature ovarian insufficiency mice with mesenchymal stem cells transplantation: The involved molecular and immunological mechanisms

Na Yin, Chao Luo, Lun Wei, Guangzhao Yang, Le Bo, Caiping Mao

J Ovarian Res. 2024; 17: 75. Published online 2024 Apr 4. doi: 10.1186/s13048-024-01390-8

PMCID:: PMC10996253

Abstract Article PDF–7.8M

Select item 109836593.

MicroRNA-21a-5p inhibition alleviates systemic sclerosis by targeting STAT3 signaling

Jin-Sil Park, Chongtae Kim, JeongWon Choi, Ha Yeon Jeong, Young-Mee Moon, Hoin Kang, Eun Kyung Lee, Mi-La Cho, Sung-Hwan Park

J Transl Med. 2024; 22: 323. Published online 2024 Apr 1. doi: 10.1186/s12967-024-05056-3

PMCID:: PMC10983659

Abstract Article PDF–18M

Select item 109198974.

Loss of MicroRNA-21 Protects Against Acetaminophen-Induced Hepatotoxicity in Mice

Alexandra M. Huffman, Maryam Syed, Samar Rezq, Christopher D. Anderson, Licy L. Yanes Cardozo, Damian G. Romero

Arch Toxicol. Author manuscript; available in PMC 2024 Jul 1.

Published in final edited form as: Arch Toxicol. 2023 Jul; 97(7): 1907–1925. Published online 2023 May 14. doi: 10.1007/s00204-023-03499-z

PMCID:: PMC10919897

Abstract Article PDF–2.4M

Select item 100531065.

MiR-21-5p regulates the dynamic of mitochondria network and rejuvenates the senile phenotype of bone marrow stromal cells (BMSCs) isolated from osteoporotic SAM/P6 mice

Mateusz Sikora, Agnieszka Śmieszek, Ariadna Pielok, Krzysztof Marycz

Stem Cell Res Ther. 2023; 14: 54. Published online 2023 Mar 29. doi: 10.1186/s13287-023-03271-1

PMCID:: PMC10053106

Abstract Article PDF–11M

Select item 97508766.

MicroRNA-21 guide and passenger strand regulation of adenylosuccinate lyase-mediated purine metabolism promotes transition to an EGFR-TKI-tolerant persister state

Wen Cai Zhang, Nicholas Skiados, Fareesa Aftab, Cerena Moreno, Luis Silva, Paul Joshua Anthony Corbilla, John M. Asara, Aaron N. Hata, Frank J. Slack

Cancer Gene Ther. 2022; 29(12): 1878–1894. Published online 2022 Jul 15. doi: 10.1038/s41417-022-00504-y

Correction in:: Cancer Gene Ther. 2022; 29(12): 2013.

PMCID:: PMC9750876

Abstract Article PDF–2.4M

Select item 95269717.

miR21 deletion in osteocytes has direct and indirect effects on skeletal muscle in a sex-dimorphic manner in mice

Alyson L. Essex, Padmini Deosthale, Joshua R. Huot, Hannah M. Davis, Nicholas Momeni, Andrea Bonetto, Lilian I. Plotkin

Biol Sex Differ. 2022; 13: 56. Published online 2022 Oct 1. doi: 10.1186/s13293-022-00465-9

PMCID:: PMC9526971

Abstract Article PDF–1.3M

Select item 86325428.

MicroRNA-21 Regulates Diametrically Opposed Biological Functions of Regulatory T Cells

Jijun Sun, Ruiling Liu, Xiaozhen He, Jiang Bian, Wenbo Zhao, Weiyun Shi, Qingguo Ruan

Front Immunol. 2021; 12: 766757. Published online 2021 Nov 11. doi: 10.3389/fimmu.2021.766757

PMCID:: PMC8632542

Abstract Article PDF–7.6M

Select item 83364899.

Platelet‐Like Fusogenic Liposome‐Mediated Targeting Delivery of miR‐21 Improves Myocardial Remodeling by Reprogramming Macrophages Post Myocardial Ischemia‐Reperfusion Injury

Haipeng Tan, Ya'nan Song, Jing Chen, Ning Zhang, Qiaozi Wang, Qiyu Li, Jinfeng Gao, Hongbo Yang, Zheng Dong, Xueyi Weng, Zhengmin Wang, Dili Sun, Wusiman Yakufu, Zhiqing Pang, Zheyong Huang, Junbo Ge

Adv Sci (Weinh) 2021 Aug; 8(15): 2100787. Published online 2021 Jun 17. doi: 10.1002/advs.202100787

PMCID:: PMC8336489

Abstract Article PDF–9.2M

Select item 832612210.

miR-21a-5p Promotes Inflammation following Traumatic Spinal Cord Injury through Upregulation of Neurotoxic Reactive Astrocyte (A1) Polarization by Inhibiting the CNTF/STAT3/Nkrf Pathway

Yining Zhang, Tingting Meng, Jianan Chen, Ying Zhang, Jianning Kang, Xinyu Li, Guilian Yu, Lige Tian, Zhengxin Jin, Hui Dong, Xiaodi Zhang, Bin Ning

Int J Biol Sci. 2021; 17(11): 2795–2810. Published online 2021 Jul 5. doi: 10.7150/ijbs.60509

PMCID:: PMC8326122

Abstract Article PDF–3.5M

Select item 832396811.

Macrophage-derived microRNA-21 drives overwhelming glycolytic and inflammatory response during sepsis via repression of the PGE₂/IL-10 axis.

Paulo De Melo, Annie Rocio Pineros Alvarez, Xiang Ye, Amondrea Blackman, Jose Carlos Alves-Filho, Alexandra I. Medeiros, Jeffrey Rathmell, Heather Pua, C. Henrique Serezani

J Immunol. Author manuscript; available in PMC 2022 Aug 1.

Published in final edited form as: J Immunol. 2021 Aug 1; 207(3): 902–912. Published online 2021 Jul 23. doi: 10.4049/jimmunol.2001251

PMCID:: PMC8323968

Abstract Article PDF–1.6M

Select item 818484312.

Improvement of hyperlipidemia by aerobic exercise in mice through a regulatory effect of miR-21a-5p on its target genes

Jinfeng Zhao, Yicun Song, Yu Zeng, Longchang Chen, Feng Yan, Anping Chen, Baoai Wu, Yaxin Wang

Sci Rep. 2021; 11: 11966. Published online 2021 Jun 7. doi: 10.1038/s41598-021-91583-8

PMCID:: PMC8184843

Abstract Article PDF–8.0M

Select item 813741513.

MicroRNA-21 inhibition attenuates airway inflammation and remodelling by modulating the transforming growth factor β–Smad7 pathway

Jung Hur, Chin Kook Rhee, Sook Young Lee, Young Kyoon Kim, Ji Young Kang

Korean J Intern Med. 2021 May; 36(3): 706–720. Published online 2021 Feb 18. doi: 10.3904/kjim.2020.132

PMCID:: PMC8137415

Abstract Article PDF–8.7M

Select item 803221414.

MicroRNA-21–Dependent Macrophage-to-Fibroblast Signaling Determines the Cardiac Response to Pressure Overload

Deepak Ramanujam, Anna Patricia Schön, Christina Beck, Paula Vaccarello, Giulia Felician, Anne Dueck, Dena Esfandyari, Gunter Meister, Thomas Meitinger, Christian Schulz, Stefan Engelhardt

Circulation. 2021 Apr 13; 143(15): 1513–1525. Published online 2021 Feb 8. doi: 10.1161/CIRCULATIONAHA.120.050682

PMCID:: PMC8032214

Abstract Article PDF–3.1M

Select item 795039015.

MicroRNA signature in diabetic wound healing: promotive role of miR‐21 in fibroblast migration

R Madhyastha, H Madhyastha, Y Nakajima, S Omura, M Maruyama

Int Wound J. 2012 Aug; 9(4): 355–361. Published online 2011 Nov 9. doi: 10.1111/j.1742-481X.2011.00890.x

PMCID:: PMC7950390

Abstract Article PDF–828K

Select item 793767616.

Photoreceptor protection by mesenchymal stem cell transplantation identifies exosomal MiR-21 as a therapeutic for retinal degeneration

Chun-Lei Deng, Cheng-Biao Hu, Sheng-Tao Ling, Na Zhao, Li-Hui Bao, Feng Zhou, Ye-Cheng Xiong, Tao Chen, Bing-Dong Sui, Xiao-Rui Yu, Cheng-Hu Hu

Cell Death Differ. 2021 Mar; 28(3): 1041–1061. Published online 2020 Oct 20. doi: 10.1038/s41418-020-00636-4

PMCID:: PMC7937676

Abstract Article PDF–8.1M

Select item 790532817.

Size changes in miR-21 knockout mice: Geometric morphometrics on teeth, alveolar bone and mandible

Uwe Yacine Schwarze, Yuxin Ni, Yanmin Zhou, Lucia Terlecki-Zaniewicz, Markus Schosserer, Matthias Hackl, Johannes Grillari, Reinhard Gruber

Mol Med Rep. 2021 Apr; 23(4): 285. Published online 2021 Feb 18. doi: 10.3892/mmr.2021.11924

PMCID:: PMC7905328

Abstract Article PDF–1.4M

Select item 784956318.

MicroRNA-21 maintains hematopoietic stem cell homeostasis through sustaining the nuclear factor-B signaling pathway in mice

Mengjia Hu, Yukai Lu, Hao Zeng, Zihao Zhang, Shilei Chen, Yan Qi, Yang Xu, Fang Chen, Yong Tang, Mo Chen, Changhong Du, Mingqiang Shen, Fengchao Wang, Yongping Su, Song Wang, Junping Wang

Haematologica. 2021 Feb 1; 106(2): 412–423. Published online 2020 Jan 23. doi: 10.3324/haematol.2019.236927