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Items: 1 to 20 of 54

1.
Mechanical stretch increases Kv1.5 current through an interaction between the S1–S2 linker and N-terminus of the channel
Alexandria O. Milton, Tingzhong Wang, Wentao Li, Jun Guo, Shetuan Zhang
J Biol Chem. 2020 Apr 3; 295(14): 4723–4732. Published online 2020 Mar 2. doi: 10.1074/jbc.RA119.011302
PMCID:
PMC7136002
AbstractArticlePDF–2.6M
2.
Challenges Faced with Small Molecular Modulators of Potassium Current Channel Isoform Kv1.5
Zefeng Zhao, Songsong Ruan, Xiaoming Ma, Qian Feng, Zhuosong Xie, Zhuang Nie, Peinan Fan, Mingcheng Qian, Xirui He, Shaoping Wu, Yongmin Zhang, Xiaohui Zheng
Biomolecules. 2020 Jan; 10(1): 10. Published online 2019 Dec 19. doi: 10.3390/biom10010010
PMCID:
PMC7022446
AbstractArticlePDF–18M
3.
The N terminus and transmembrane segment S1 of Kv1.5 can coassemble with the rest of the channel independently of the S1–S2 linkage
Shawn M. Lamothe, Aja E. Hogan-Cann, Wentao Li, Jun Guo, Tonghua Yang, Jared N. Tschirhart, Shetuan Zhang
J Biol Chem. 2018 Oct 5; 293(40): 15347–15358. Published online 2018 Aug 17. doi: 10.1074/jbc.RA118.004065
PMCID:
PMC6177590
AbstractArticlePDF–2.7M
4.
In silico assessment of genetic variation in KCNA5 reveals multiple mechanisms of human atrial arrhythmogenesis
Michael A. Colman, Haibo Ni, Bo Liang, Nicole Schmitt, Henggui Zhang
PLoS Comput Biol. 2017 Jun; 13(6): e1005587. Published online 2017 Jun 16. doi: 10.1371/journal.pcbi.1005587
PMCID:
PMC5493429
AbstractArticlePDF–13M
5.
Putative binding sites for arachidonic acid on the human cardiac Kv1.5 channel
Jia‐Yu Bai, Wei‐Guang Ding, Akiko Kojima, Tomoyoshi Seto, Hiroshi Matsuura
Br J Pharmacol. 2015 Nov; 172(22): 5281–5292. Published online 2015 Oct 22. doi: 10.1111/bph.13314
PMCID:
PMC5341216
AbstractArticlePDF–2.1M
6.
Promoter Methylation Analysis Reveals that KCNA5 Ion Channel Silencing Supports Ewing Sarcoma Cell Proliferation
Katherine E Ryland, Allegra G. Hawkins, Daniel J. Weisenberger, Vasu Punj, Scott C. Borinstein, Peter W. Laird, Jeffrey R. Martens, Elizabeth R. Lawlor
Mol Cancer Res. Author manuscript; available in PMC 2017 Jan 1.
Published in final edited form as: Mol Cancer Res. 2016 Jan; 14(1): 26–34. Published online 2015 Nov 16. doi: 10.1158/1541-7786.MCR-15-0343
PMCID:
PMC4716008
AbstractArticlePDF–1.3M
7.
Silencing of Kv1.5 Gene Inhibits Proliferation and Induces Apoptosis of Osteosarcoma Cells
Jin Wu, Zhida Chen, Qingjun Liu, Wenrong Zeng, Xinyu Wu, Bin Lin
Int J Mol Sci. 2015 Nov; 16(11): 26914–26926. Published online 2015 Nov 11. doi: 10.3390/ijms161126002
PMCID:
PMC4661860
AbstractArticlePDF–6.2M
8.
Polycomb-Dependent Repression of the Potassium Channel-Encoding Gene KCNA5 Promotes Cancer Cell Survival Under Conditions of Stress
Katherine E Ryland, Laurie K. Svoboda, Eileen D Vesely, Jeremy C. McIntyre, Lian Zhang, Jeffrey R. Martens, Elizabeth R. Lawlor
Oncogene. Author manuscript; available in PMC 2016 Feb 27.
Published in final edited form as: Oncogene. 2015 Aug 27; 34(35): 4591–4600. Published online 2014 Dec 1. doi: 10.1038/onc.2014.384
PMCID:
PMC4451446
AbstractArticlePDF–2.5M
9.
Remodeling of Kv1.5 Channel in Right Atria from Han Chinese Patients with Atrial Fibrillation
Xian-hong Ou, Miao-ling Li, Rui Liu, Xin-rong Fan, Liang Mao, Xue-hui Fan, Yan Yang, Xiao-rong Zeng
Med Sci Monit. 2015; 21: 1207–1213. Published online 2015 Apr 28. doi: 10.12659/MSM.893533
PMCID:
PMC4424910
AbstractArticlePDF–368K
10.
Improved Functional Expression of Human Cardiac Kv1.5 Channels and Trafficking-Defective Mutants by Low Temperature Treatment
Wei-Guang Ding, Yu Xie, Futoshi Toyoda, Hiroshi Matsuura
PLoS One. 2014; 9(3): e92923. Published online 2014 Mar 24. doi: 10.1371/journal.pone.0092923
PMCID:
PMC3963980
AbstractArticlePDF–1.4M
11.
KCNA5 gene is not confirmed as a systemic sclerosis-related pulmonary arterial hypertension genetic susceptibility factor
Lara Bossini-Castillo, Carmen P Simeon, Lorenzo Beretta, Jasper Broen, Madelon C Vonk, José Luis Callejas, Patricia Carreira, Luis Rodríguez-Rodríguez, Rosa García-Portales, Miguel A González-Gay, Ivan Castellví, María Teresa Camps, Carlos Tolosa, Esther Vicente-Rabaneda, María Victoria Egurbide, Annemie J Schuerwegh, Roger Hesselstrand, Claudio Lunardi, Jacob M van Laar, Paul Shiels, Ariane Herrick, Jane Worthington, Christopher Denton, Timothy RDJ Radstake, Carmen Fonseca, Javier Martin
Arthritis Res Ther. 2012; 14(6): R273. Published online 2012 Dec 27. doi: 10.1186/ar4124
PMCID:
PMC3674598
AbstractArticlePDF–209K
12.
Kinetic analysis of the effects of H+ or Ni2+ on Kv1.5 current shows that both ions enhance slow inactivation and induce resting inactivation
Yen May Cheng, David Fedida, Steven J Kehl
J Physiol. 2010 Aug 15; 588(Pt 16): 3011–3030. Published online 2010 Jun 25. doi: 10.1113/jphysiol.2010.191544
PMCID:
PMC2956942
AbstractArticlePDF–944K
13.
A novel KCNA5 Mutation Implicates Tyrosine Kinase Signaling in Human Atrial Fibrillation
Tao Yang, Ping Yang, Dan M. Roden, Dawood Darbar
Heart Rhythm. Author manuscript; available in PMC 2010 Sep 3.
Published in final edited form as: Heart Rhythm. 2010 Sep; 7(9): 1246–1252. Published online 2010 Jun 1. doi: 10.1016/j.hrthm.2010.05.032
PMCID:
PMC2932792
AbstractArticlePDF–1007K
14.
Tetramerization domain mutations in KCNA5 affect channel kinetics and cause abnormal trafficking patterns
Elyssa D. Burg, Oleksandr Platoshyn, Igor F. Tsigelny, Beatriz Lozano-Ruiz, Brinda K. Rana, Jason X.-J. Yuan
Am J Physiol Cell Physiol. 2010 Mar; 298(3): C496–C509. Published online 2009 Dec 16. doi: 10.1152/ajpcell.00464.2009
PMCID:
PMC2838577
AbstractArticle
15.
A pilot study to estimate the feasibility of assessing the relationships between polymorphisms in hKv1.5 and atrial fibrillation in patients following coronary artery bypass graft surgery
Isabelle Plante, Dominique Fournier, Patrick Mathieu, Pascal Daleau
Can J Cardiol. 2008 Jan; 24(1): 41–44. doi: 10.1016/s0828-282x(08)70546-4
PMCID:
PMC2631247
AbstractArticlePDF–160K
16.
Kv Channel Gating Requires a Compatible S4-S5 Linker and Bottom Part of S6, Constrained by Non-interacting Residues
Alain J. Labro, Adam L. Raes, Alessandro Grottesi, Diane Van Hoorick, Mark S.P. Sansom, Dirk J. Snyders
J Gen Physiol. 2008 Dec; 132(6): 667–680. doi: 10.1085/jgp.200810048
PMCID:
PMC2585865
AbstractArticlePDF–3.5M
17.
Coupling of Voltage Sensing to Channel Opening Reflects Intrasubunit Interactions in Kv Channels
Alain J. Labro, Adam L. Raes, Dirk J. Snyders
J Gen Physiol. 2005 Jan; 125(1): 71–80. doi: 10.1085/jgp.200409194
PMCID:
PMC2217479
AbstractArticlePDF–1.9M
18.
Rapid Induction of P/C-type Inactivation Is the Mechanism for Acid-induced K+ Current Inhibition
Shetuan Zhang, Harley T. Kurata, Steven J. Kehl, David Fedida
J Gen Physiol. 2003 Mar; 121(3): 215–225. doi: 10.1085/jgp.20028760
PMCID:
PMC2217332
AbstractArticlePDF–1.0M
19.
KV1.5–KVβ1.3 Recycling Is PKC-Dependent
Alvaro Macias, Alicia de la Cruz, Diego A. Peraza, Angela de Benito-Bueno, Teresa Gonzalez, Carmen Valenzuela
Int J Mol Sci. 2021 Feb; 22(3): 1336. Published online 2021 Jan 29. doi: 10.3390/ijms22031336
PMCID:
PMC7866247
AbstractArticlePDF–2.1M
20.
Selective expression of KCNA5 and KCNB1 genes in gastric and colorectal carcinoma
Azer Farah, Maria Kabbage, Salsabil Atafi, Amira Jaballah Gabteni, Mouadh Barbirou, Mouna Madhioub, Lamine Hamzaoui, Mousadak Azzouz Mohamed, Hassen Touinsi, Asma Ouakaa Kchaou, Emna Chelbi, Samir Boubaker, Rahma Ben Abderrazek, Balkiss Bouhaouala-Zahar
BMC Cancer. 2020; 20: 1179. Published online 2020 Dec 2. doi: 10.1186/s12885-020-07647-x
PMCID:
PMC7709444
AbstractArticlePDF–1.3M

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