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Select item 111847531.

CRISPR/Cas9-mediated knock out of ITGB6 in human OSCC cells reduced migration and proliferation ability

Maximilian Geyer, Fabian Geyer, Ute Reuning, Sarah Klapproth, Klaus-Dietrich Wolff, Markus Nieberler

Head Face Med. 2024; 20: 37. Published online 2024 Jun 18. doi: 10.1186/s13005-024-00437-x

PMCID:: PMC11184753

Abstract Article PDF–3.9M

Select item 49706762.

Expansion of the spectrum of ITGB6-related disorders to adolescent alopecia, dentogingival abnormalities and intellectual disability

Muhammad Ansar, Abid Jan, Regie Lyn P Santos-Cortez, Xin Wang, Muhammad Suliman, Anushree Acharya, Rabia Habib, Izoduwa Abbe, Ghazanfar Ali, Kwanghyuk Lee, Joshua D Smith, University of Washington Center for Mendelian Genomics, Deborah A Nickerson, Jay Shendure, Michael J Bamshad, Wasim Ahmad, Suzanne M Leal

Eur J Hum Genet. 2016 Aug; 24(8): 1223–1227. Published online 2015 Dec 23. doi: 10.1038/ejhg.2015.260

PMCID:: PMC4970676

Abstract Article PDF–1.6M

Select item 48736073.

High expression of integrin β6 in association with the Rho–Rac pathway identifies a poor prognostic subgroup within HER2 amplified breast cancers

Krisha Desai, Madhumathy G. Nair, Jyothi S. Prabhu, Anupama Vinod, Aruna Korlimarla, Savitha Rajarajan, Radhika Aiyappa, Rohini S. Kaluve, Annie Alexander, P. S. Hari, Geetashree Mukherjee, Rekha V. Kumar, Suraj Manjunath, Marjorrie Correa, B. S. Srinath, Shekhar Patil, M. S. N. Prasad, K. S. Gopinath, Raman N. Rao, Shelia M. Violette, Paul H. Weinreb, T. S. Sridhar

Cancer Med. 2016 Aug; 5(8): 2000–2011. Published online 2016 May 17. doi: 10.1002/cam4.756

PMCID:: PMC4873607

Abstract Article PDF–523K

Select item 44403864.

Novel ITGB6 mutation in autosomal recessive amelogenesis imperfecta

F Seymen, K-E Lee, M Koruyucu, K Gencay, M Bayram, EB Tuna, ZH Lee, J-W Kim

Oral Dis. 2015 May; 21(4): 456–461. Published online 2015 Jan 19. doi: 10.1111/odi.12303

PMCID:: PMC4440386

Abstract Article PDF–801K

Select item 43768835.

Cloning and Characterization of the Human Integrin β6 Gene Promoter

Mingyan Xu, Xihe Chen, Hao Yin, Liqin Yin, Fan Liu, Yucai Fu, Jiangwu Yao, Xiaoling Deng

PLoS One. 2015; 10(3): e0121439. Published online 2015 Mar 27. doi: 10.1371/journal.pone.0121439

PMCID:: PMC4376883

Abstract Article PDF–3.3M

Select item 29641296.

Skin wound healing in diabetic ß6 integrin deficient mice

Jasper N. Jacobsen, Bjørn Steffensen, Lari Hâkkinen, Karen A. Krogfelt, Hannu S. Larjava

APMIS. Author manuscript; available in PMC 2011 Oct 1.

Published in final edited form as: APMIS. 2010 Oct; 118(10): 753–764. Published online 2010 Aug 17. doi: 10.1111/j.1600-0463.2010.02654.x

PMCID:: PMC2964129

Abstract Article PDF–795K

Select item 17526037.

Expression of α and β subunits of the integrin superfamily in articular cartilage from macroscopically normal and osteoarthritic human femoral heads

K. Ostergaard, D. Salter, J. Petersen, K. Bendtzen, J. Hvolris, C. Andersen

Ann Rheum Dis. 1998 May; 57(5): 303–308. doi: 10.1136/ard.57.5.303

PMCID:: PMC1752603

Summary PDF–145K

Select item 110288138.

Integrin alphavbeta6 promotes tumor tolerance in colorectal cancer

Shao-Bo Yang, Yun Du, Ben-Yan Wu, Shi-Ping Xu, Jun-Bao Wen, Min Zhu, Chang-Hao Cai, Ping-Chang Yang

Cancer Immunol Immunother. 2012 Mar; 61(3): 335–342. Published online 2011 Sep 13. doi: 10.1007/s00262-011-1108-1

PMCID:: PMC11028813

Abstract Article PDF–396K

Select item 90771409.

Extracellular vesicles rich in HAX1 promote angiogenesis by modulating ITGB6 translation

Bo You, Si Pan, Miao Gu, Kaiwen Zhang, Tian Xia, Siyu Zhang, Wenhui Chen, Haijing Xie, Yue Fan, Hui Yao, Tianyi Cheng, Panpan Zhang, Dong Liu, Yiwen You

J Extracell Vesicles. 2022 May; 11(5): e12221. Published online 2022 May 6. doi: 10.1002/jev2.12221

Correction in:: J Extracell Vesicles. 2022 Jun; 11(6): e12236.

PMCID:: PMC9077140

Abstract Article PDF–13M

Select item 823126610.

ITGB6-Knockout Suppresses Cholangiocarcinoma Cell Migration and Invasion with Declining PODXL2 Expression

Yurie Soejima, Miho Takeuchi, Nao Miyamoto, Motoji Sawabe, Toshio Fukusato

Int J Mol Sci. 2021 Jun; 22(12): 6303. Published online 2021 Jun 11. doi: 10.3390/ijms22126303

PMCID:: PMC8231266

Abstract Article PDF–7.4M

Select item 793393211.

Transgenic overexpression of ITGB6 in intestinal epithelial cells exacerbates dextran sulfate sodium‐induced colitis in mice

Haiyan Chen, Liubo Chen, Xin Wang, Xiaoxu Ge, Lifeng Sun, Zhanhuai Wang, Xiaoming Xu, Yongmao Song, Jing Chen, Qun Deng, Haiting Xie, Ting Chen, Yan Chen, Kefeng Ding, Jingjing Wu, Jian Wang

J Cell Mol Med. 2021 Mar; 25(5): 2679–2690. Published online 2021 Jan 24. doi: 10.1111/jcmm.16297

PMCID:: PMC7933932

Abstract Article PDF–2.1M

Select item 744303512.

Interleukin-6 Promotes Epithelial-Mesenchymal Transition and Cell Invasion through Integrin β6 Upregulation in Colorectal Cancer

Qi Sun, Yukui Shang, Fengkai Sun, Xiwen Dong, Jun Niu, Fanni Li

Oxid Med Cell Longev. 2020; 2020: 8032187. Published online 2020 Aug 13. doi: 10.1155/2020/8032187

PMCID:: PMC7443035

Abstract Article PDF–1.8M

Select item 704870813.

Integrin αvβ6 mediates epithelial-mesenchymal transition in human bronchial epithelial cells induced by lipopolysaccharides of Pseudomonas aeruginosa via TGF-β1-Smad2/3 signaling pathway

Weiming Liu, Tieying Sun, Yong Wang

Folia Microbiol (Praha) 2020; 65(2): 329–338. Published online 2019 Jun 26. doi: 10.1007/s12223-019-00728-w

PMCID:: PMC7048708

Abstract Article PDF–1.1M

Select item 685243414.

The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy

Claire S Reader, Sabari Vallath, Colin W Steele, Syed Haider, Adam Brentnall, Ami Desai, Kate M Moore, Nigel B Jamieson, David Chang, Peter Bailey, Aldo Scarpa, Rita Lawlor, Claude Chelala, Stephen M Keyse, Andrew Biankin, Jennifer P Morton, TR Jeffry Evans, Simon T Barry, Owen J Sansom, Hemant M Kocher, John F Marshall

J Pathol. 2019 Nov; 249(3): 332–342. Published online 2019 Jul 30. doi: 10.1002/path.5320

PMCID:: PMC6852434

Abstract Article PDF–4.8M

Select item 643551615.

Integrin αvβ6 plays a bi-directional regulation role between colon cancer cells and cancer-associated fibroblasts

Cheng Peng, Xueqing Zou, Wanying Xia, Huijie Gao, Zequn Li, Naiqing Liu, Zongquan Xu, Chao Gao, Zhaobin He, Weibo Niu, Ruliang Fang, Siddhartha Biswas, Michael Agrez, Xuting Zhi, Jun Niu

Biosci Rep. 2018 Dec 21; 38(6): BSR20180243. Prepublished online 2018 Oct 24. Published online 2018 Dec 7. doi: 10.1042/BSR20180243

PMCID:: PMC6435516

Abstract Article PDF–1.3M

Select item 545752016.

Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus

Abhay Kotecha, Quan Wang, Xianchi Dong, Serban L. Ilca, Marina Ondiviela, Rao Zihe, Julian Seago, Bryan Charleston, Elizabeth E. Fry, Nicola G. A. Abrescia, Timothy A. Springer, Juha T. Huiskonen, David I. Stuart

Nat Commun. 2017; 8: 15408. Published online 2017 May 23. doi: 10.1038/ncomms15408

PMCID:: PMC5457520

Abstract Article PDF–4.1M

Select item 495499217.

Integrin β6 serves as an immunohistochemical marker for lymph node metastasis and promotes cell invasiveness in cholangiocarcinoma

Zequn Li, Siddhartha Biswas, Benjia Liang, Xueqing Zou, Liqun Shan, Yang Li, Ruliang Fang, Jun Niu

Sci Rep. 2016; 6: 30081. Published online 2016 Jul 21. doi: 10.1038/srep30081

PMCID:: PMC4954992

Abstract Article PDF–2.5M

Select item 395982018.

ITGB6 loss-of-function mutations cause autosomal recessive amelogenesis imperfecta

Shih-Kai Wang, Murim Choi, Amelia S. Richardson, Bryan M. Reid, Brent P. Lin, Susan J. Wang, Jung-Wook Kim, James P. Simmer, Jan C.-C. Hu

Hum Mol Genet. 2014 Apr 15; 23(8): 2157–2163. Published online 2013 Dec 4. doi: 10.1093/hmg/ddt611

PMCID:: PMC3959820

Abstract Article PDF–930K

Select item 288334519.

Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes

Lu Qi, Marilyn C. Cornelis, Peter Kraft, Kristopher J. Stanya, W.H. Linda Kao, James S. Pankow, Josée Dupuis, Jose C. Florez, Caroline S. Fox, Guillaume Paré, Qi Sun, Cynthia J. Girman, Cathy C. Laurie, Daniel B. Mirel, Teri A. Manolio, Daniel I. Chasman, Eric Boerwinkle, Paul M. Ridker, David J. Hunter, James B. Meigs, Chih-Hao Lee, Meta-Analysis of Glucose and Insulin-related traits Consortium (MAGIC), Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium, Rob M. van Dam, Frank B. Hu

Hum Mol Genet. 2010 Jul 1; 19(13): 2706–2715. Published online 2010 Apr 23. doi: 10.1093/hmg/ddq156

PMCID:: PMC2883345

Abstract Article PDF–328K

Select item 278716120.

Fusion of epithelial cells by Epstein–Barr virus proteins is triggered by binding of viral glycoproteins gHgL to integrins αvβ6 or αvβ8

Liudmila S. Chesnokova, Stephen L. Nishimura, Lindsey M. Hutt-Fletcher

Proc Natl Acad Sci U S A. 2009 Dec 1; 106(48): 20464–20469. Published online 2009 Nov 17. doi: 10.1073/pnas.0907508106

Correction in:: Proc Natl Acad Sci U S A. 2010 Feb 16; 107(7): 3275.

PMCID:: PMC2787161

Abstract Article PDF–1000K

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