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Select item 110275041.

ITGAL expression in non-small-cell lung cancer tissue and its association with immune infiltrates

Ruihao Zhang, Guangsheng Zhu, Zaishan Li, Zhenzhen Meng, Hua Huang, Chen Ding, Yanan Wang, Chen Chen, Yongwen Li, Hongyu Liu, Jun Chen

Front Immunol. 2024; 15: 1382231. Published online 2024 Apr 4. doi: 10.3389/fimmu.2024.1382231

Correction in:: Front Immunol. 2024; 15: 1415814.

PMCID:: PMC11027504

Abstract Article PDF–14M

Select item 107768562.

LFA-1 nanoclusters integrate TCR stimulation strength to tune T-cell cytotoxic activity

Claire Lacouture, Beatriz Chaves, Delphine Guipouy, Raïssa Houmadi, Valérie Duplan-Eche, Sophie Allart, Nicolas Destainville, Loïc Dupré

Nat Commun. 2024; 15: 407. Published online 2024 Jan 9. doi: 10.1038/s41467-024-44688-3

PMCID:: PMC10776856

Abstract Article PDF–4.6M

Select item 92463853.

LFA-1 activation enriches tumor-specific T cells in a cold tumor model and synergizes with CTLA-4 blockade

Amber Hickman, Joost Koetsier, Trevin Kurtanich, Michael C. Nielsen, Glenn Winn, Yunfei Wang, Salah-Eddine Bentebibel, Leilei Shi, Simone Punt, Leila Williams, Cara Haymaker, Charles B. Chesson, Faisal Fa’ak, Ana L. Dominguez, Richard Jones, Isere Kuiatse, Amy R. Caivano, Sayadeth Khounlo, Navin D. Warier, Upendra Marathi, Robert V. Market, Ronald J. Biediger, John W. Craft, Jr., Patrick Hwu, Michael A. Davies, Darren G. Woodside, Peter Vanderslice, Adi Diab, Willem W. Overwijk, Yared Hailemichael

J Clin Invest. 2022 Jul 1; 132(13): e154152. Published online 2022 Jul 1. doi: 10.1172/JCI154152

PMCID:: PMC9246385

Abstract Article PDF–11M

Select item 47300464.

Expression of CD11a in lymphocyte subpopulation in immune thrombocytopenia

Yan-Xia Liu, Feng Zhang, Qing-Min Yao, Ting Yuan, Jian Xu, Xiao-Juan Zhu

Int J Clin Exp Pathol. 2015; 8(12): 15642–15651. Published online 2015 Dec 1.

PMCID:: PMC4730046

Abstract Article PDF–600K

Select item 42792285.

FRET detection of lymphocyte function–associated antigen-1 conformational extension

Alexandre Chigaev, Yelena Smagley, Mark K. Haynes, Oleg Ursu, Cristian G. Bologa, Liliana Halip, Tudor Oprea, Anna Waller, Mark B. Carter, Yinan Zhang, Wei Wang, Tione Buranda, Larry A. Sklar

Mol Biol Cell. 2015 Jan 1; 26(1): 43–54. doi: 10.1091/mbc.E14-06-1050

PMCID:: PMC4279228

Abstract Article PDF–4.5M

Select item 42411106.

NMR characterization of the conformational fluctuations of the human lymphocyte function-associated antigen-1 I-domain

Hoi Tik Alvin Leung, Predrag Kukic, Carlo Camilloni, Francesco Bemporad, Alfonso De Simone, Francesco A Aprile, Janet R Kumita, Michele Vendruscolo

Protein Sci. 2014 Nov; 23(11): 1596–1606. Published online 2014 Sep 5. doi: 10.1002/pro.2538

PMCID:: PMC4241110

Abstract Article PDF–539K

Select item 35721387.

Suppression of LFA-1 Expression by Spermine Is Associated with Enhanced Methylation of ITGAL, the LFA-1 Promoter Area

Yoshihiko Kano, Kuniyasu Soda, Fumio Konishi

PLoS One. 2013; 8(2): e56056. Published online 2013 Feb 13. doi: 10.1371/journal.pone.0056056

PMCID:: PMC3572138

Abstract Article PDF–581K

Select item 33668138.

Leukotoxin (Leukothera®) Targets Active Leukocyte Function Antigen-1 (LFA-1) Protein and Triggers a Lysosomal Mediated Cell Death Pathway

Kristina M. DiFranco, Anukriti Gupta, Lindsey E. Galusha, Jarelys Perez, To-Vy K. Nguyen, Camille D. Fineza, Scott C. Kachlany

J Biol Chem. 2012 May 18; 287(21): 17618–17627. Published online 2012 Mar 30. doi: 10.1074/jbc.M111.314674

PMCID:: PMC3366813

Abstract Article PDF–2.4M

Select item 33239699.

Lateral mobility of individual integrin nanoclusters orchestrates the onset for leukocyte adhesion

Gert Jan Bakker, Christina Eich, Juan A. Torreno-Pina, Ruth Diez-Ahedo, Gemma Perez-Samper, Thomas S. van Zanten, Carl G. Figdor, Alessandra Cambi, Maria F. Garcia-Parajo

Proc Natl Acad Sci U S A. 2012 Mar 27; 109(13): 4869-4874. Published online 2012 Mar 12. doi: 10.1073/pnas.1116425109

PMCID:: PMC3323969

Abstract Article PDF–2.2M

Select item 317323810.

The Bordetella pertussis adenylate cyclase toxin binds to T cells via LFA-1 and induces its disengagement from the immune synapse

Silvia Rossi Paccani, Francesca Finetti, Marilyne Davi, Laura Patrussi, Mario M. D'Elios, Daniel Ladant, Cosima T. Baldari

J Exp Med. 2011 Jun 6; 208(6): 1317–1330. doi: 10.1084/jem.20101558

PMCID:: PMC3173238

Abstract Article PDF–2.5M

Select item 280310511.

Lymphocyte Crawling and Transendothelial Migration Require Chemokine Triggering of High-Affinity LFA-1 Integrin

Ziv Shulman, Vera Shinder, Eugenia Klein, Valentin Grabovsky, Orna Yeger, Erez Geron, Alessio Montresor, Matteo Bolomini-Vittori, Sara W. Feigelson, Tomas Kirchhausen, Carlo Laudanna, Guy Shakhar, Ronen Alon

Immunity. Author manuscript; available in PMC 2010 Jan 7.

Published in final edited form as: Immunity. 2009 Mar 20; 30(3): 384–396. Published online 2009 Mar 5. doi: 10.1016/j.immuni.2008.12.020

PMCID:: PMC2803105

Abstract Article PDF–1.5M

Select item 266811512.

Enhancement of LFA-1-Mediated T Cell Adhesion by Human T Lymphotropic Virus Type 1 p12^I

Seung-jae Kim, Amrithraj M. Nair, Soledad Fernandez, Lawrence Mathes, Michael D. Lairmore

J Immunol. Author manuscript; available in PMC 2009 Apr 13.

Published in final edited form as: J Immunol. 2006 May 1; 176(9): 5463–5470. doi: 10.4049/jimmunol.176.9.5463

PMCID:: PMC2668115

Abstract Article PDF–3.1M

Select item 217156813.

Specific integrin α and β chain phosphorylations regulate LFA-1 activation through affinity-dependent and -independent mechanisms

Susanna C. Fagerholm, Tiina J. Hilden, Susanna M. Nurmi, Carl G. Gahmberg

J Cell Biol. 2005 Nov 21; 171(4): 705–715. doi: 10.1083/jcb.200504016

PMCID:: PMC2171568

Abstract Article PDF–2.2M

Select item 214799914.

Intermediate-affinity LFA-1 binds α-actinin-1 to control migration at the leading edge of the T cell

Paula Stanley, Andrew Smith, Alison McDowall, Alastair Nicol, Daniel Zicha, Nancy Hogg

EMBO J. 2008 Jan 9; 27(1): 62–75. Published online 2007 Dec 13. doi: 10.1038/sj.emboj.7601959

PMCID:: PMC2147999

Abstract Article PDF–641K

Select item 211543015.

Primary structure of the leukocyte function-associated molecule-1 alpha subunit: an integrin with an embedded domain defining a protein superfamily

J Cell Biol. 1989 Feb 1; 108(2): 703–712. doi: 10.1083/jcb.108.2.703

PMCID:: PMC2115430

Summary PDF–1.3M

Select item 190627716.

Differential expression of β1 and β2 integrins and L-selectin on CD4⁺ and CD8⁺ T lymphocytes in human blood: comparative analysis between isolated cells, whole blood samples and cryopreserved preparations

M Cavers, B Afzali Khoshkbijari, M Macey, D A Mccarthy, S Irshad, K A Brown

Clin Exp Immunol. 2002 Jan; 127(1): 60–65. doi: 10.1046/j.1365-2249.2002.01711.x

Correction in:: Clin Exp Immunol. 2005 Jul; 141(1): 189–190.

PMCID:: PMC1906277

Abstract Article PDF–149K

Select item 163535717.

Organization of the Integrin LFA-1 in Nanoclusters Regulates Its Activity

Alessandra Cambi, Ben Joosten, Marjolein Koopman, Frank de Lange, Inge Beeren, Ruurd Torensma, Jack A. Fransen, Maria Garcia-Parajó, Frank N. van Leeuwen, Carl G. Figdor

Mol Biol Cell. 2006 Oct; 17(10): 4270–4281. doi: 10.1091/mbc.E05-12-1098

PMCID:: PMC1635357

Abstract Article PDF–1.9M

Select item 159990118.

AL-57, a ligand-mimetic antibody to integrin LFA-1, reveals chemokine-induced affinity up-regulation in lymphocytes

Motomu Shimaoka, Minsoo Kim, Edward H. Cohen, Wei Yang, Nathan Astrof, Dan Peer, Azucena Salas, Audrey Ferrand, Timothy A. Springer

Proc Natl Acad Sci U S A. 2006 Sep 19; 103(38): 13991–13996. Published online 2006 Sep 8. doi: 10.1073/pnas.0605716103

PMCID:: PMC1599901

Abstract Article PDF–458K

Select item 155975319.

Regulation of outside-in signaling and affinity by the β₂ I domain of integrin α_Lβ₂

JianFeng Chen, Wei Yang, Minsoo Kim, Christopher V. Carman, Timothy A. Springer

Proc Natl Acad Sci U S A. 2006 Aug 29; 103(35): 13062–13067. Published online 2006 Aug 18. doi: 10.1073/pnas.0605666103

PMCID:: PMC1559753

Abstract Article PDF–584K

Select item 145340520.

Differential function of LFA-1 family molecules (CD11 and CD18) in adhesion of human monocytes to melanoma and endothelial cells.

A A te Velde, G D Keizer, C G Figdor

Immunology. 1987 Jul; 61(3): 261–267.

PMCID:: PMC1453405

Summary Page Browse PDF–1.0M

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