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Select item 80024961.

Interferon Regulatory Factor 5 (IRF5) Gene Haplotypes Are Associated with Premature Coronary Artery Disease. Association of the IRF5 Polymorphisms with Cardiometabolic Parameters. The Genetics of Atherosclerotic Disease (GEA) Mexican Study

Rosalinda Posadas-Sánchez, Guillermo Cardoso-Saldaña, José Manuel Fragoso, Gilberto Vargas-Alarcón

Biomolecules. 2021 Mar; 11(3): 443. Published online 2021 Mar 17. doi: 10.3390/biom11030443

PMCID:: PMC8002496

Article PDF–1.1M

Select item 71406732.

Enhanced Adipose Expression of Interferon Regulatory Factor (IRF)-5 Associates with the Signatures of Metabolic Inflammation in Diabetic Obese Patients

Sardar Sindhu, Shihab Kochumon, Reeby Thomas, Abdullah Bennakhi, Fahd Al-Mulla, Rasheed Ahmad

Cells. 2020 Mar; 9(3): 730. Published online 2020 Mar 16. doi: 10.3390/cells9030730

PMCID:: PMC7140673

Article PDF–3.0M

Select item 70987223.

IRF5 genetic risk variants drive myeloid-specific IRF5 hyperactivation and presymptomatic SLE

Dan Li, Bharati Matta, Su Song, Victoria Nelson, Kirsten Diggins, Kim R. Simpfendorfer, Peter K. Gregersen, Peter Linsley, Betsy J. Barnes

JCI Insight. 2020 Jan 30; 5(2): e124020. Published online 2020 Jan 30. doi: 10.1172/jci.insight.124020

PMCID:: PMC7098722

Article PDF–5.2M

Select item 69126764.

Increased Adipose Tissue Expression of Interferon Regulatory Factor (IRF)-5 in Obesity: Association with Metabolic Inflammation

Sardar Sindhu, Reeby Thomas, Shihab Kochumon, Ajit Wilson, Mohamed Abu-Farha, Abdullah Bennakhi, Fahd Al-Mulla, Rasheed Ahmad

Cells. 2019 Nov; 8(11): 1418. Published online 2019 Nov 11. doi: 10.3390/cells8111418

PMCID:: PMC6912676

Article PDF–5.3M

Select item 65854315.

IRF5 is required for Bacterial Clearance in Human M1-Polarized Macrophages and IRF5 Immune-Mediated Disease Risk Variants Modulate This Outcome

Matija Hedl, Jie Yan, Heiko Witt, Clara Abraham

J Immunol. Author manuscript; available in PMC 2020 Feb 1.

Published in final edited form as: J Immunol. 2019 Feb 1; 202(3): 920–930. Published online 2018 Dec 28. doi: 10.4049/jimmunol.1800226

PMCID:: PMC6585431

Article PDF–1.8M

Select item 65634456.

Advances and challenges in targeting IRF5, a key regulator of inflammation

Hannah Almuttaqi, Irina A. Udalova

FEBS J. 2019 May; 286(9): 1624–1637. Published online 2018 Sep 21. doi: 10.1111/febs.14654

PMCID:: PMC6563445

Article PDF–677K

Select item 64640317.

FcγR-TLR Cross-Talk Enhances TNF Production by Human Monocyte-Derived DCs via IRF5-Dependent Gene Transcription and Glycolytic Reprogramming

Willianne Hoepel, Melissa Newling, Lisa T. C. Vogelpoel, Lathees Sritharan, Ivo S. Hansen, Martien L. Kapsenberg, Dominique L. P. Baeten, Bart Everts, Jeroen den Dunnen

Front Immunol. 2019; 10: 739. Published online 2019 Apr 8. doi: 10.3389/fimmu.2019.00739

PMCID:: PMC6464031

Article PDF–5.1M

Select item 61181518.

The IRF5 rs2004640 (G/T) polymorphism is not a genetic risk factor for systemic lupus erythematosus in population from south India

Panneer Devaraju, Sonal Mehra, Reena Gulati, Paul T. Antony, Vikramraj K. Jain, Durga Prasanna Misra, Vir Singh Negi

Indian J Med Res. 2018 Jun; 147(6): 560–566. doi: 10.4103/ijmr.IJMR_2025_16

PMCID:: PMC6118151

Article PDF–342K

Select item 59495279.

Lineage-Specific Functionality of an Interferon Regulatory Factor 5 Lupus Risk Haplotype: Lack of B Cell Intrinsic Effects

Justine Calise, Susana Marquez Renteria, Peter K. Gregersen, Betty Diamond

Front Immunol. 2018; 9: 996. Published online 2018 May 7. doi: 10.3389/fimmu.2018.00996

PMCID:: PMC5949527

Article PDF–3.9M

Select item 576894310.

Genetic variants of interferon regulatory factor 5 associated with chronic hepatitis B infection

Bui Tien Sy, Nghiem Xuan Hoan, Hoang Van Tong, Christian G Meyer, Nguyen Linh Toan, Le Huu Song, Claus-Thomas Bock, Thirumalaisamy P Velavan

World J Gastroenterol. 2018 Jan 14; 24(2): 248–256. Published online 2018 Jan 14. doi: 10.3748/wjg.v24.i2.248

PMCID:: PMC5768943

Article PDF–7.7M

Select item 576693311.

Interferon regulatory factor 5 (IRF5) suppresses hepatitis C virus (HCV) replication and HCV-associated hepatocellular carcinoma

Ozge Cevik, Dan Li, Erdene Baljinnyam, Dinesh Manvar, Erica M. Pimenta, Gulam Waris, Betsy J. Barnes, Neerja Kaushik-Basu

J Biol Chem. 2017 Dec 29; 292(52): 21676–21689. Published online 2017 Oct 27. doi: 10.1074/jbc.M117.792721

PMCID:: PMC5766933

Article PDF–2.7M

Select item 575174912.

Assessment of DNA methylation at the interferon regulatory factor 5 (IRF5) promoter region in inflammatory bowel diseases

Alfred Balasa, Grace Gathungu, Peter Kisfali, E O'Brian Smith, Judy H. Cho, Bela Melegh, Richard Kellermayer

Int J Colorectal Dis. Author manuscript; available in PMC 2018 Jan 3.

Published in final edited form as: Int J Colorectal Dis. 2010 May; 25(5): 553–556. Published online 2010 Feb 2. doi: 10.1007/s00384-010-0874-0

PMCID:: PMC5751749

Article PDF–318K

Select item 554647213.

IRF5 is associated with adverse postoperative prognosis of patients with non-metastatic clear cell renal cell carcinoma

Qi Bai, Li Liu, Yu Xia, Jiajun Wang, Wei Xi, Yang Qu, Ying Xiong, Qilai Long, Jiejie Xu, Jianming Guo

Oncotarget. 2017 Jul 4; 8(27): 44186–44194. Published online 2017 May 11. doi: 10.18632/oncotarget.17777

PMCID:: PMC5546472

Article PDF–8.1M

Select item 483671114.

A Combination of CD28 (rs1980422) and IRF5 (rs10488631) Polymorphisms Is Associated with Seropositivity in Rheumatoid Arthritis: A Case Control Study

Lucia Vernerova, Frantisek Spoutil, Miroslav Vlcek, Katarina Krskova, Adela Penesova, Milada Meskova, Andrea Marko, Katarina Raslova, Branislav Vohnout, Jozef Rovensky, Zdenko Killinger, Ivana Jochmanova, Ivica Lazurova, Guenter Steiner, Josef Smolen, Richard Imrich

PLoS One. 2016; 11(4): e0153316. Published online 2016 Apr 19. doi: 10.1371/journal.pone.0153316

PMCID:: PMC4836711

Article PDF–628K

Select item 473372615.

Variants of Interferon Regulatory Factor 5 are Associated with Neither Neuromyelitis Optica Nor Multiple Sclerosis in the Southeastern Han Chinese Population

Qi-Bing Liu, Lei Wu, Gui-Xian Zhao, Ping-Ping Cai, Zhen-Xin Li, Zhi-Ying Wu

Chin Med J (Engl) 2015 Jul 5; 128(13): 1743–1747. doi: 10.4103/0366-6999.159347

PMCID:: PMC4733726

Article PDF–318K

Select item 465423116.

Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women

Morgane Griesbeck, Susanne Ziegler, Sophie Laffont, Nikaïa Smith, Lise Chauveau, Phillip Tomezsko, Armon Sharei, Georgio Kourjian, Filippos Porichis, Meghan Hart, Christine D. Palmer, Michael Sirignano, Claudia Beisel, Heike Hildebrandt, Claire Cénac, Alexandra-Chloé Villani, Thomas J. Diefenbach, Sylvie Le Gall, Olivier Schwartz, Jean-Philippe Herbeuval, Brigitte Autran, Jean-Charles Guéry, J. Judy Chang, Marcus Altfeld

J Immunol. 2015 Dec 1; 195(11): 5327–5336. Published online 2015 Oct 30. doi: 10.4049/jimmunol.1501684

PMCID:: PMC4654231

Article PDF–857K

Select item 432637117.

A conserved region within interferon regulatory factor 5 controls breast cancer cell migration through a cytoplasmic and transcription-independent mechanism

Erica Maria Pimenta, Betsy J Barnes

Mol Cancer. 2015; 14(1): 32. Published online 2015 Feb 4. doi: 10.1186/s12943-015-0305-5

PMCID:: PMC4326371

Article PDF–1.9M

Select item 422704118.

Interferon regulatory factor 5 genetic variants are associated with cardiovascular disease in patients with rheumatoid arthritis

Mercedes García-Bermúdez, Raquel López-Mejías, Fernanda Genre, Santos Castañeda, Javier Llorca, Carlos González-Juanatey, Alfonso Corrales, Begoña Ubilla, José A Miranda-Filloy, Trinitario Pina, Carmen Gómez-Vaquero, Luis Rodríguez-Rodríguez, Benjamín Fernández-Gutiérrez, Alejandro Balsa, Dora Pascual-Salcedo, Francisco J López-Longo, Patricia Carreira, Ricardo Blanco, Javier Martín, Miguel A González-Gay

Arthritis Res Ther. 2014; 16(4): R146. Published online 2014 Jul 10. doi: 10.1186/ar4608

PMCID:: PMC4227041

Article PDF–194K

Select item 397892119.

Identification of three new cis-regulatory IRF5 polymorphisms: in vitro studies

Elisa Alonso-Perez, Romina Fernandez-Poceiro, Emilie Lalonde, Tony Kwan, Manuel Calaza, Juan J Gomez-Reino, Jacek Majewski, Antonio Gonzalez

Arthritis Res Ther. 2013; 15(4): R82. Published online 2013 Aug 13. doi: 10.1186/ar4262

PMCID:: PMC3978921

Article PDF–1.4M

Select item 380999020.

A two-marker haplotype in the IRF5 gene is associated with inflammatory bowel disease in a North American cohort

G Gathungu, CK Zhang, W Zhang, JH Cho

Genes Immun. Author manuscript; available in PMC 2013 Oct 28.

Published in final edited form as: Genes Immun. 2012 Jun; 13(4): 10.1038/gene.2011.90. Published online 2012 Jan 19. doi: 10.1038/gene.2011.90

PMCID:: PMC3809990

Article PDF–227K

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