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Select item 99803021.

IL‐7 germline variant: setting the stage for immune‐related adverse events

Hussein Issaoui, Jean‐Ehrland Ricci

Mol Oncol. 2023 Mar; 17(3): 384–386. Published online 2023 Feb 24. doi: 10.1002/1878-0261.13392

PMCID:: PMC9980302

Abstract Article PDF–121K

Select item 98002752.

IL7 genetic variation and toxicity to immune checkpoint blockade in patients with melanoma

Chelsea A. Taylor, Robert A. Watson, Orion Tong, Weiyu Ye, Isar Nassiri, James J. Gilchrist, Alba Verge de los Aires, Piyush Kumar Sharma, Surya Koturan, Rosalin A. Cooper, Victoria K. Woodcock, Elsita Jungkurth, Brian Shine, Nicholas Coupe, Miranda J. Payne, David N. Church, Vivek Naranbhai, Stefan Groha, Paul Emery, Kulveer Mankia, Matthew L. Freedman, Toni K. Choueiri, Mark R. Middleton, Alexander Gusev, Benjamin P. Fairfax

Nat Med. 2022; 28(12): 2592–2600. Published online 2022 Dec 16. doi: 10.1038/s41591-022-02095-5

PMCID:: PMC9800275

Abstract Article PDF–16M

Select item 92954183.

Interleukin-7 regulates CD127 expression and promotes CD8⁺ T cell activity in patients with primary cutaneous melanoma

Hongxia He, Binjun Qiao, Shuping Guo, Hongzhou Cui, Ziyan Zhang, Junxia Qin

BMC Immunol. 2022; 23: 35. Published online 2022 Jul 18. doi: 10.1186/s12865-022-00509-0

PMCID:: PMC9295418

Abstract Article PDF–3.6M

Select item 85711374.

IL-7 coupled with IL-12 increases intratumoral T cell clonality, leading to complete regression of non-immunogenic tumors

Mamoru Tasaki, Midori Yamashita, Yukinori Arai, Takafumi Nakamura, Shinsuke Nakao

Cancer Immunol Immunother. 2021 Dec; 70(12): 3557–3571. Published online 2021 Apr 28. doi: 10.1007/s00262-021-02947-y

PMCID:: PMC8571137

Abstract Article PDF–3.9M

Select item 85240085.

Role of Interleukin-7 in the Development of and Recovery from Radiation-Induced Lymphopenia: A Post-hoc Analysis of a Prospective Cohort

Hwa Kyung Byun, Seung Yeun Chung, Kyoung-Jin Kim, Jinsil Seong

Cancer Res Treat. 2021 Oct; 53(4): 962–972. Published online 2021 Jan 26. doi: 10.4143/crt.2020.1053

PMCID:: PMC8524008

Abstract Article PDF–1.2M

Select item 82782886.

Internal Disulfide Bonding and Glycosylation of Interleukin-7 Protect Against Proteolytic Inactivation by Neutrophil Metalloproteinases and Serine Proteases

Jennifer Vandooren, Rafaela Vaz Sousa Pereira, Estefania Ugarte-Berzal, Vasily Rybakin, Sam Noppen, Melissa R. Stas, Eline Bernaerts, Eva Ganseman, Mieke Metzemaekers, Dominique Schols, Paul Proost, Ghislain Opdenakker

Front Immunol. 2021; 12: 701739. Published online 2021 Jun 30. doi: 10.3389/fimmu.2021.701739

PMCID:: PMC8278288

Abstract Article PDF–5.3M

Select item 80645177.

Gene fusion of IL7 involved in the regulation of idiopathic pulmonary fibrosis

Shixue Sun, Chen Huang, Dongliang Leng, Chang Chen, Teng Zhang, Kuan Cheok Lei, Xiaohua Douglas Zhang

Ther Adv Respir Dis. 2021 Jan-Dec; 15: 1753466621995045. Published online 2021 Apr 20. doi: 10.1177/1753466621995045

PMCID:: PMC8064517

Abstract Article PDF–1.8M

Select item 73377528.

Serum Cytokine and Chemokine Profile in Relation to the Severity of Coronavirus Disease 2019 in China

Ying Chi, Yiyue Ge, Bin Wu, Wenshuai Zhang, Tao Wu, Tian Wen, Jingxian Liu, Xiling Guo, Chao Huang, Yongjun Jiao, Fengcai Zhu, Baoli Zhu, Lunbiao Cui

J Infect Dis. 2020 Sep 1; 222(5): 746–754. Published online 2020 Jun 21. doi: 10.1093/infdis/jiaa363

PMCID:: PMC7337752

Abstract Article PDF–2.5M

Select item 68185739.

Interleukin‐7 gene polymorphism rs766736182 associates with the risk of asthma in children

Junhua Cao, Lijun Tian, Zhenguang Li, Chonglin Zhang, Qiang Ji, Chuanling Zhang, Tong Qian

J Clin Lab Anal. 2019 Feb; 33(2): e22675. Published online 2018 Sep 21. doi: 10.1002/jcla.22675

PMCID:: PMC6818573

Abstract Article PDF–242K

Select item 669801010.

Genetic variation in interleukin-7 is associated with a reduced erythropoietic response in Kenyan children infected with Plasmodium falciparum

Lily E. Kisia, Prakasha Kempaiah, Samuel B. Anyona, Elly O. Munde, Angela O. Achieng, John M. Ong’echa, Christophe G. Lambert, Kiprotich Chelimo, Collins Ouma, Douglas J. Perkins , Evans Raballah

BMC Med Genet. 2019; 20: 140. Published online 2019 Aug 16. doi: 10.1186/s12881-019-0866-z

PMCID:: PMC6698010

Abstract Article PDF–646K

Select item 659784411.

Yi-qi-yang-yin-tian-sui-fang enhances cisplatin-induced tumor eradication and inhibits interleukin-7 reduction in non-small cell lung cancer

Bin Ke, Xinlin Wu, Qiong Yang, Yuanyuan Huang, Fang Wang, Yuxin Gong, Junfang Liu, Lin Shi

Biosci Rep. 2019 Jun 28; 39(6): BSR20190052. Prepublished online 2019 May 28. Published online 2019 Jun 28. doi: 10.1042/BSR20190052

PMCID:: PMC6597844

Abstract Article PDF–1.5M

Select item 650284512.

Interleukin-7 Contributes to the Invasiveness of Prostate Cancer Cells by Promoting Epithelial–Mesenchymal Transition

Min A. Seol, Jin-Hee Kim, Keunhee Oh, Gwanghun Kim, Myung Won Seo, Young-Kyoung Shin, Ji Hyun Sim, Hyun Mu Shin, Bo Yeon Seo, Dong-Sup Lee, Ja-Lok Ku, Ilkyu Han, Insoo Kang, Serk In Park, Hang-Rae Kim

Sci Rep. 2019; 9: 6917. Published online 2019 May 6. doi: 10.1038/s41598-019-43294-4

PMCID:: PMC6502845

Abstract Article PDF–4.0M

Select item 631962213.

The common γ-chain cytokine IL-7 promotes immunopathogenesis during fungal asthma

Kristen M. Reeder, Chad W. Dunaway, Jonathan P. Blackburn, Zhihong Yu, Sadis Matalon, Annette T. Hastie, Elizabeth J. Ampleford, Deborah A. Meyers, Chad Steele

Mucosal Immunol. Author manuscript; available in PMC 2019 Jan 4.

Published in final edited form as: Mucosal Immunol. 2018 Sep; 11(5): 1352–1362. Published online 2018 Jun 15. doi: 10.1038/s41385-018-0028-1

PMCID:: PMC6319622

Abstract Article PDF–859K

Select item 597259414.

Interleukin-7 Unveils Pathogen-Specific T Cells by Enhancing Antigen-Recall Responses

Nadia Terrazzini, Paola Mantegani, Florian Kern, Claudio Fortis, Anna Mondino, Stefano Caserta

J Infect Dis. 2018 Jun 15; 217(12): 1997–2007. Published online 2018 Feb 28. doi: 10.1093/infdis/jiy096

PMCID:: PMC5972594

Abstract Article PDF–1.5M

Select item 566983015.

Constitutive signaling from an engineered IL-7 receptor promotes durable tumor elimination by tumor redirected T-cells

Thomas Shum, Bilal Omer, Haruko Tashiro, Robert L. Kruse, Dimitrios L. Wagner, Kathan Parikh, Zhongzhen Yi, Tim Sauer, Daofeng Liu, Robin Parihar, Paul Castillo, Hao Liu, Malcolm K. Brenner, Leonid S. Metelitsa, Stephen Gottschalk, Cliona M. Rooney

Cancer Discov. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: Cancer Discov. 2017 Nov; 7(11): 1238–1247. Published online 2017 Aug 22. doi: 10.1158/2159-8290.CD-17-0538

PMCID:: PMC5669830

Abstract Article PDF–1.2M

Select item 559395716.

IL-7 plays a critical role for the homeostasis of allergen-specific memory CD4 T cells in the lung and airways

Seung-min Yeon, Lea Halim, Anmol Chandele, Curtis J. Perry, Sang Hoon Kim, Sun-Uk Kim, Youngjoo Byun, Soon Hong Yuk, Susan M. Kaech, Yong Woo Jung

Sci Rep. 2017; 7: 11155. Published online 2017 Sep 11. doi: 10.1038/s41598-017-11492-7

PMCID:: PMC5593957

Abstract Article PDF–1.4M

Select item 528165317.

Elevated systemic interleukin-7 in patients with colorectal cancer and individuals at high risk of cancer: association with lymph node involvement and tumor location in the right colon

Malgorzata Krzystek-Korpacka, Marek Zawadzki, Katarzyna Neubauer, Iwona Bednarz-Misa, Sabina Górska, Jerzy Wiśniewski, Wojciech Witkiewicz, Andrzej Gamian

Cancer Immunol Immunother. 2017 Feb; 66(2): 171–179. Published online 2016 Nov 19. doi: 10.1007/s00262-016-1933-3

PMCID:: PMC5281653

Abstract Article PDF–726K

Select item 519894018.

IL-7 suppresses osteogenic differentiation of periodontal ligament stem cells through inactivation of mitogen-activated protein kinase pathway

Cong-Xiang Jian, Quan-Shui Fan, Yong-He Hu, Yong He, Ming-Zhe Li, Wei-Yin Zheng, Yu Ren, Chen-Jun Li

Organogenesis. 2016; 12(4): 183–193. Published online 2016 Aug 31. doi: 10.1080/15476278.2016.1229726

PMCID:: PMC5198940

Abstract Article PDF–491K

Select item 491427619.

Human naïve regulatory T-cells feature high steady-state turnover and are maintained by IL-7

Susana L. Silva, Adriana S. Albuquerque, Ana Serra-Caetano, Russell B. Foxall, Ana R. Pires, Paula Matoso, Susana M. Fernandes, João Ferreira, Rémi Cheynier, Rui M. M. Victorino, Iris Caramalho, João T. Barata, Ana E. Sousa

Oncotarget. 2016 Mar 15; 7(11): 12163–12175. Published online 2016 Feb 19. doi: 10.18632/oncotarget.7512

PMCID:: PMC4914276

Abstract Article PDF–3.0M

Select item 441745020.

Recycled interleukin-7 can be delivered to neighboring T cells

Douglas A. Bazdar, Magdalena Kalinowska, Soumya Panigrahi, Scott F. Sieg

J Immunol. Author manuscript; available in PMC 2016 May 15.

Published in final edited form as: J Immunol. 2015 May 15; 194(10): 4698–4704. Published online 2015 Apr 13. doi: 10.4049/jimmunol.1400560

PMCID:: PMC4417450

Abstract Article PDF–1.2M

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