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Items: 1 to 20 of 23

1.
APLP1 is endoproteolytically cleaved by γ-secretase without previous ectodomain shedding
Linda Schauenburg, Filip Liebsch, Murat Eravci, Magnus C. Mayer, Christoph Weise, Gerhard Multhaup
Sci Rep. 2018; 8: 1916. Published online 2018 Jan 30. doi: 10.1038/s41598-018-19530-8
PMCID:
PMC5789831
ArticlePDF–2.7M
2.
Direct evidence of amyloid precursor–like protein 1 trans interactions in cell–cell adhesion platforms investigated via fluorescence fluctuation spectroscopy
Valentin Dunsing, Magnus Mayer, Filip Liebsch, Gerhard Multhaup, Salvatore Chiantia
Mol Biol Cell. 2017 Dec 1; 28(25): 3609–3620. doi: 10.1091/mbc.E17-07-0459
PMCID:
PMC5706989
ArticlePDF–1.1M
3.
Interaction of the amyloid precursor protein-like protein 1 (APLP1) E2 domain with heparan sulfate involves two distinct binding modes
Sven O. Dahms, Magnus C. Mayer, Dirk Roeser, Gerd Multhaup, Manuel E. Than
Acta Crystallogr D Biol Crystallogr. 2015 Mar 1; 71(Pt 3): 494–504. Published online 2015 Feb 26. doi: 10.1107/S1399004714027114
PMCID:
PMC4356362
ArticlePDF–1.7M
4.
Turnover of Amyloid Precursor Protein Family Members Determines Their Nuclear Signaling Capability
Manuel T. Gersbacher, Zoë V. Goodger, Annette Trutzel, Diana Bundschuh, Roger M. Nitsch, Uwe Konietzko
PLoS One. 2013; 8(7): e69363. Published online 2013 Jul 18. doi: 10.1371/journal.pone.0069363
PMCID:
PMC3715505
ArticlePDF–1.6M
5.
The 28-amino acid form of an APLP1-derived Aβ-like peptide is a surrogate marker for Aβ42 production in the central nervous system
Kanta Yanagida, Masayasu Okochi, Shinji Tagami, Taisuke Nakayama, Takashi S Kodama, Kouhei Nishitomi, Jingwei Jiang, Kohji Mori, Shin-ichi Tatsumi, Tetsuaki Arai, Takeshi Ikeuchi, Kensaku Kasuga, Takahiko Tokuda, Masaki Kondo, Masaki Ikeda, Kentaro Deguchi, Hiroaki Kazui, Toshihisa Tanaka, Takashi Morihara, Ryota Hashimoto, Takashi Kudo, Harald Steiner, Christian Haass, Kuniaki Tsuchiya, Haruhiko Akiyama, Ryozo Kuwano, Masatoshi Takeda
EMBO Mol Med. 2009 Jul; 1(4): 223–235. doi: 10.1002/emmm.200900026
PMCID:
PMC3378133
ArticlePDF–1.0M
6.
Structural aspects and physiological consequences of APP/APLP trans-dimerization
Frederik Baumkötter, Katja Wagner, Simone Eggert, Klemens Wild, Stefan Kins
Exp Brain Res. 2012; 217(3): 389–395. Published online 2011 Sep 28. doi: 10.1007/s00221-011-2878-6
PMCID:
PMC3308009
ArticlePDF–246K
7.
Crystal structure of amyloid precursor-like protein 1 and heparin complex suggests a dual role of heparin in E2 dimerization
Yi Xue, Sangwon Lee, Ya Ha
Proc Natl Acad Sci U S A. 2011 Sep 27; 108(39): 16229-16234. Published online 2011 Sep 19. doi: 10.1073/pnas.1103407108
PMCID:
PMC3182750
ArticlePDF–1.3M
8.
The E2 domains of APP and APLP1 share a conserved mode of dimerization
Sangwon Lee, Yi Xue, Jian Hu, Yongcheng Wang, Xuying Liu, Borries Demeler, Ya Ha
Biochemistry. Author manuscript; available in PMC 2012 Jun 21.
Published in final edited form as: Biochemistry. 2011 Jun 21; 50(24): 5453–5464. Published online 2011 May 26. doi: 10.1021/bi101846x
PMCID:
PMC3120129
ArticlePDF–2.3M
9.
Mediator is a transducer of amyloid-precursor-protein-dependent nuclear signalling
Xuan Xu, Haiying Zhou, Thomas G Boyer
EMBO Rep. 2011 Mar 3; 12(3): 216–222. Published online 2011 Feb 4. doi: 10.1038/embor.2010.210
PMCID:
PMC3059912
ArticlePDF–758K
10.
Binding of F-spondin to amyloid-β precursor protein: A candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage
Angela Ho, Thomas C. Südhof
Proc Natl Acad Sci U S A. 2004 Feb 24; 101(8): 2548–2553. Published online 2004 Feb 17. doi: 10.1073/pnas.0308655100
PMCID:
PMC356987
ArticlePDF–452K
11.
Amyolid precursor protein mediates presynaptic localization and activity of the high-affinity choline transporter
Baiping Wang, Li Yang, Zilai Wang, Hui Zheng
Proc Natl Acad Sci U S A. 2007 Aug 28; 104(35): 14140–14145. Published online 2007 Aug 20. doi: 10.1073/pnas.0704070104
PMCID:
PMC1955810
ArticlePDF–443K
12.
Disabled-1 Binds to the Cytoplasmic Domain of Amyloid Precursor-Like Protein 1
Ramin Homayouni, Dennis S. Rice, Michael Sheldon, Tom Curran
J Neurosci. 1999 Sep 1; 19(17): 7507–7515. doi: 10.1523/JNEUROSCI.19-17-07507.1999
PMCID:
PMC6782519
ArticlePDF–633K
13.
Homo- and heterodimerization of APP family members promotes intercellular adhesion
Peter Soba, Simone Eggert, Katja Wagner, Hanswalter Zentgraf, Katjuscha Siehl, Sylvia Kreger, Alexander Löwer, Andreas Langer, Gunter Merdes, Renato Paro, Colin L Masters, Ulrike Müller, Stefan Kins, Konrad Beyreuther
EMBO J. 2005 Oct 19; 24(20): 3624–3634. Published online 2005 Sep 29. doi: 10.1038/sj.emboj.7600824
Correction in:
EMBO J. 2006 Feb 8; 25(3): 653.
PMCID:
PMC1276707
ArticlePDF–645K
14.
The Identification of Novel Proteins That Interact With the GLP-1 Receptor and Restrain its Activity
X. Huang, F. F. Dai, G. Gaisano, K. Giglou, J. Han, M. Zhang, S. Kittanakom, V. Wong, L. Wei, A. D. Showalter, K. W. Sloop, I. Stagljar, M. B. Wheeler
Mol Endocrinol. September 1, 2013; 27(9): 1550–1563. Published online 2013 Jul 17. doi: 10.1210/me.2013-1047
PMCID:
PMC5415235
Article
15.
Functional specialization of β-arrestin interactions revealed by proteomic analysis
Kunhong Xiao, Daniel B. McClatchy, Arun K. Shukla, Yang Zhao, Minyong Chen, Sudha K. Shenoy, John R. Yates, III, Robert J. Lefkowitz
Proc Natl Acad Sci U S A. 2007 Jul 17; 104(29): 12011–12016. Published online 2007 Jul 9. doi: 10.1073/pnas.0704849104
PMCID:
PMC1913545
ArticlePDF–712K
16.
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch
Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9
PMCID:
PMC6981206
ArticlePDF–3.7M
17.
Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes
Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano
Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406
PMCID:
PMC1356129
ArticlePDF–438K
18.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
ArticlePDF–2.2M
19.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
ArticlePDF–2.7M
20.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
ArticlePDF–2.2M

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