PMC Links for Gene (Select 320910) - PMC

Result Filters

Links from Gene

Items: 1 to 20 of 59

<< First< Prev

Page of 3

Select item 43419741.

Selective Targeting of TGF-β Activation to Treat Fibroinflammatory Airway Disease

Shunsuke Minagawa, Jianlong Lou, Robert I. Seed, Anthony Cormier, Shenping Wu, Yifan Cheng, Lynne Murray, Ping Tsui, Jane Connor, Ronald Herbst, Cedric Govaerts, Tyren Barker, Stephanie Cambier, Haruhiko Yanagisawa, Amanda Goodsell, Mitsuo Hashimoto, Oliver J. Brand, Ran Cheng, Royce Ma, Kate J. McKnelly, Weihua Wen, Arthur Hill, David Jablons, Paul Wolters, Hideya Kitamura, Jun Araya, Andrea J. Barczak, David J. Erle, Louis F. Reichardt, James D. Marks, Jody L. Baron, Stephen L. Nishimura

Sci Transl Med. Author manuscript; available in PMC 2015 Feb 26.

Published in final edited form as: Sci Transl Med. 2014 Jun 18; 6(241): 241ra79. doi: 10.1126/scitranslmed.3008074

PMCID:: PMC4341974

Abstract Article PDF–2.1M

Select item 26946192.

β8 integrin regulates neurogenesis and neurovascular homeostasis in the adult brain

Aaron K. Mobley, Jeremy H. Tchaicha, Jaekyung Shin, Mohammad G. Hossain, Joseph H. McCarty

J Cell Sci. 2009 Jun 1; 122(11): 1842–1851. Published online 2009 May 20. doi: 10.1242/jcs.043257

Correction in:: J Cell Sci. 2009 Jul 1; 122(13): 2322.

PMCID:: PMC2694619

Abstract Article

Select item 83214143.

Integrin αvβ8 on T cells suppresses anti-tumor immunity in multiple models and is a promising target for tumor immunotherapy

Eswari Dodagatta-Marri, Hsiao-Yen Ma, Benjia Liang, John Li, Dominique S. Meyer, Szu-Ying Chen, Kai-Hui Sun, Xin Ren, Bahar Zivak, Michael D. Rosenblum, Mark B. Headley, Lauren Pinzas, Nilgun I. Reed, Joselyn S. Del Cid, Byron C. Hann, Sharon Yang, Anand Giddabasappa, Kavon Noorbehesht, Bing Yang, Joseph Dal Porto, Tatsuya Tsukui, Kyle Niessen, Amha Atakilit, Rosemary J. Akhurst, Dean Sheppard

Cell Rep. Author manuscript; available in PMC 2021 Jul 29.

Published in final edited form as: Cell Rep. 2021 Jul 6; 36(1): 109309. doi: 10.1016/j.celrep.2021.109309

PMCID:: PMC8321414

Abstract Article PDF–2.3M

Select item 69396084.

Migratory DCs activate TGF-β to precondition naive CD8⁺ T cells for tissue-resident memory fate

Vinidhra Mani, Shannon K. Bromley, Tarmo Äijö, Rut Mora-Buch, Esteban Carrizosa, Ross D. Warner, Moustafa Hamze, Debattama R. Sen, Alexandra Y. Chasse, Alina Lorant, Jason W. Griffith, Rod A. Rahimi, Craig P. McEntee, Kate L. Jeffrey, Francesco Marangoni, Mark A. Travis, Adam Lacy-Hulbert, Andrew D. Luster, Thorsten R. Mempel

Science. Author manuscript; available in PMC 2020 Apr 11.

Published in final edited form as: Science. 2019 Oct 11; 366(6462): eaav5728. doi: 10.1126/science.aav5728

PMCID:: PMC6939608

Abstract Article PDF–2.7M

Select item 63603545.

Loss of Integrin αvβ8 in Murine Hepatocytes Accelerates Liver Regeneration

Stephen N. Greenhalgh, Kylie P. Matchett, Richard S. Taylor, Katherine Huang, John T. Li, Koy Saeteurn, Mhairi C. Donnelly, Eilidh E.M. Simpson, Joshua L. Pollack, Amha Atakilit, Kenneth J. Simpson, Jacquelyn J. Maher, John P. Iredale, Dean Sheppard, Neil C. Henderson

Am J Pathol. 2019 Feb; 189(2): 258–271. doi: 10.1016/j.ajpath.2018.10.007

PMCID:: PMC6360354

Abstract Article

Select item 59735936.

Role of integrin alpha8 in murine model of lung fibrosis

Chi F. Hung, Carole L. Wilson, Yu-Hua Chow, Lynn M. Schnapp

PLoS One. 2018; 13(5): e0197937. Published online 2018 May 29. doi: 10.1371/journal.pone.0197937

PMCID:: PMC5973593

Abstract Article PDF–8.8M

Select item 50657817.

Integrin β8 Deletion Enhances Vascular Dysplasia and Hemorrhage in the Brain of Adult Alk1 Heterozygous Mice

Li Ma, Fanxia Shen, Kristine Jun, Chen Bao, Robert Kuo, William L. Young, Stephen L. Nishimura, Hua Su

Transl Stroke Res. Author manuscript; available in PMC 2017 Dec 1.

Published in final edited form as: Transl Stroke Res. 2016 Dec; 7(6): 488–496. Published online 2016 Jun 29. doi: 10.1007/s12975-016-0478-2

PMCID:: PMC5065781

Abstract Article PDF–1.0M

Select item 34133738.

An In Vivo Map of Bone Morphogenetic Protein 2 Post-transcriptional Repression in the Heart

Boudewijn P. T. Kruithof, Junwang Xu, David T. Fritz, Carolina S. Cabral, Vinciane Gaussin, Melissa B. Rogers

Genesis. Author manuscript; available in PMC 2012 Aug 7.

Published in final edited form as: Genesis. 2011 Nov; 49(11): 841–850. Published online 2011 Oct 14. doi: 10.1002/dvg.20757

PMCID:: PMC3413373

Abstract Article PDF–3.4M

Select item 29935959.

Expression of αvβ8 integrin on dendritic cells regulates Th17 cell development and experimental autoimmune encephalomyelitis in mice

Andrew C. Melton, Samantha L. Bailey-Bucktrout, Mark A. Travis, Brian T. Fife, Jeffrey A. Bluestone, Dean Sheppard

J Clin Invest. 2010 Dec 1; 120(12): 4436–4444. Published online 2010 Nov 22. doi: 10.1172/JCI43786

PMCID:: PMC2993595

Abstract Article PDF–1.2M

Select item 866356810.

αVβ8 integrin targeting to prevent posterior capsular opacification

Mahbubul H. Shihan, Samuel G. Novo, Yan Wang, Dean Sheppard, Amha Atakilit, Thomas D. Arnold, Nicole M. Rossi, Adam P. Faranda, Melinda K. Duncan

JCI Insight. 2021 Nov 8; 6(21): e145715. Published online 2021 Nov 8. doi: 10.1172/jci.insight.145715

PMCID:: PMC8663568

Abstract Article PDF–4.5M

Select item 855394211.

Regulatory T cells promote cancer immune-escape through integrin αvβ8-mediated TGF-β activation

Alexandra Lainé, Ossama Labiad, Hector Hernandez-Vargas, Sébastien This, Amélien Sanlaville, Sophie Léon, Stéphane Dalle, Dean Sheppard, Mark A. Travis, Helena Paidassi, Julien C. Marie

Nat Commun. 2021; 12: 6228. Published online 2021 Oct 28. doi: 10.1038/s41467-021-26352-2

PMCID:: PMC8553942

Abstract Article PDF–3.2M

Select item 549127312.

Pharmacologic Blockade of αvβ1 Integrin Ameliorates Renal Failure and Fibrosis In Vivo

Yongen Chang, Wei Ling Lau, Hyunil Jo, Kazuyuki Tsujino, Leslie Gewin, Nilgun Isik Reed, Amha Atakilit, Ane Claudia Fernandes Nunes, William F. DeGrado, Dean Sheppard

J Am Soc Nephrol. 2017 Jul; 28(7): 1998–2005. Published online 2017 Feb 20. doi: 10.1681/ASN.2015050585

PMCID:: PMC5491273

Abstract Article

Select item 437270413.

Protein Tyrosine Phosphatase-PEST and β8 Integrin Regulate Spatiotemporal Patterns of RhoGDI1 Activation in Migrating Cells

Hye Shin Lee, Mujeeburahiman Cheerathodi, Sankar P. Chaki, Steve B. Reyes, Yanhua Zheng, Zhimin Lu, Helena Paidassi, Celine DerMardirossian, Adam Lacy-Hulbert, Gonzalo M. Rivera, Joseph H. McCarty

Mol Cell Biol. 2015 Apr; 35(8): 1401–1413. Prepublished online 2015 Feb 9. Published online 2015 Mar 24. doi: 10.1128/MCB.00112-15

PMCID:: PMC4372704

Abstract Article PDF–3.1M

Select item 405997414.

Mesangial cell α_vβ₈-integrin regulates glomerular capillary integrity and repair

Sujata Lakhe-Reddy, Vincent Li, Thomas D. Arnold, Shenaz Khan, Jeffrey R. Schelling

Am J Physiol Renal Physiol. 2014 Jun 15; 306(12): F1400–F1409. Published online 2014 Apr 16. doi: 10.1152/ajprenal.00624.2013

PMCID:: PMC4059974

Abstract Article

Select item 353784715.

Production of Gastrointestinal Tumors in Mice by Modulating Latent Transforming Growth Factor Beta 1 Activation

Kotaro Shibahara, Mitsuhiko Ota, Masahito Horiguchi, Keiji Yoshinaga, Jonathan Melamed, Daniel B Rifkin

Cancer Res. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: Cancer Res. 2013 Jan 1; 73(1): 459–468. Published online 2012 Nov 1. doi: 10.1158/0008-5472.CAN-12-3141

PMCID:: PMC3537847

Abstract Article PDF–2.1M

Select item 325303616.

The astrocyte-expressed integrin αvβ8 governs blood vessel sprouting in the developing retina

Shinya Hirota, Qian Liu, Hye Shin Lee, Mohammad G. Hossain, Adam Lacy-Hulbert, Joseph H. McCarty

Development. 2011 Dec 1; 138(23): 5157–5166. doi: 10.1242/dev.069153

PMCID:: PMC3253036

Abstract Article

Select item 303776717.

A Mosaic Mouse Model of Astrocytoma Identifies avß8 Integrin as an Essential Regulator of Tumor-Induced Angiogenesis

Jeremy H. Tchaicha, Aaron K. Mobley, Mohammad G. Hossain, Kenneth D. Aldape, Joseph H. McCarty

Oncogene. Author manuscript; available in PMC 2011 Feb 11.

Published in final edited form as: Oncogene. 2010 Aug 5; 29(31): 4460–4472. Published online 2010 Jun 7. doi: 10.1038/onc.2010.199

PMCID:: PMC3037767

Abstract Article PDF–1.8M

Select item 271189318.

β8 Integrin Binds Rho GDP Dissociation Inhibitor-1 and Activates Rac1 to Inhibit Mesangial Cell Myofibroblast Differentiation

Sujata Lakhe-Reddy, Shenaz Khan, Martha Konieczkowski, George Jarad, Karen L. Wu, Louis F. Reichardt, Yoshimi Takai, Leslie A. Bruggeman, Bingcheng Wang, John R. Sedor, Jeffrey R. Schelling

J Biol Chem. Author manuscript; available in PMC 2009 Jul 16.

Published in final edited form as: J Biol Chem. 2006 Jul 14; 281(28): 19688–19699. Published online 2006 May 11. doi: 10.1074/jbc.M601110200