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Select item 106663561.

circ-hnRNPU inhibits NONO-mediated c-Myc transactivation and mRNA stabilization essential for glycosylation and cancer progression

Hongjun Li, Wanju Jiao, Jiyu Song, Jianqun Wang, Guo Chen, Dan Li, Xiaojing Wang, Banghe Bao, Xinyi Du, Yang Cheng, Chunhui Yang, Qiangsong Tong, Liduan Zheng

J Exp Clin Cancer Res. 2023; 42: 313. Published online 2023 Nov 23. doi: 10.1186/s13046-023-02898-5

PMCID:: PMC10666356

Article PDF–8.2M

Select item 105813862.

Deficiency of the Heterogeneous Nuclear Ribonucleoprotein U locus leads to delayed hindbrain neurogenesis

Francesca Mastropasqua, Marika Oksanen, Cristina Soldini, Shemim Alatar, Abishek Arora, Roberto Ballarino, Maya Molinari, Federico Agostini, Axel Poulet, Michelle Watts, Ielyzaveta Rabkina, Martin Becker, Danyang Li, Britt-Marie Anderlid, Johan Isaksson, Karl Lundin Remnelius, Mohsen Moslem, Yannick Jacob, Anna Falk, Nicola Crosetto, Magda Bienko, Emanuela Santini, Anders Borgkvist, Sven Bölte, Kristiina Tammimies

Biol Open. 2023 Oct 15; 12(10): bio060113. Published online 2023 Oct 10. doi: 10.1242/bio.060113

PMCID:: PMC10581386

Article PDF–5.3M

Select item 104741283.

Germline pathogenic variants in HNRNPU are associated with alterations in blood methylome

Sunwoo Lee, Eguzkine Ochoa, Magdalena Badura-Stronka, Deirdre Donnelly, Damien Lederer, Sally A. Lynch, Alice Gardham, Jenny Morton, Helen Stewart, France Docquier, Fay Rodger, Ezequiel Martin, Ana Toribio, Eamonn R. Maher, Meena Balasubramanian

Eur J Hum Genet. 2023 Sep; 31(9): 1040–1047. Published online 2023 Jul 5. doi: 10.1038/s41431-023-01422-9

PMCID:: PMC10474128

Article PDF–1.5M

Select item 96434204.

HNRNPU promotes the progression of triple-negative breast cancer via RNA transcription and alternative splicing mechanisms

Bo-yue Han, Zhebin Liu, Xin Hu, Hong Ling

Cell Death Dis. 2022 Nov; 13(11): 940. Published online 2022 Nov 8. doi: 10.1038/s41419-022-05376-6

PMCID:: PMC9643420

Article PDF–7.0M

Select item 96134925.

hnRNP U在急性髓系白血病中临床意义及致病机制研究

徐春丽, 陈玙, 朱婷婷, 孙振江, 储剑虹

Zhonghua Xue Ye Xue Za Zhi. 2022 Sep; 43(9): 745–752. Chinese. doi: 10.3760/cma.j.issn.0253-2727.2022.09.006

PMCID:: PMC9613492

Article PDF–20M

Select item 92760356.

Heterogeneous nuclear ribonucleoprotein U-actin complex derived from extracellular vesicles facilitates proliferation and migration of human coronary artery endothelial cells by promoting RNA polymerase II transcription

Han Wang, Hengdao Liu, Xi Zhao, Xiaowei Chen

Bioengineered. 2022; 13(5): 11469–11486. Published online 2022 May 9. doi: 10.1080/21655979.2022.2066754

PMCID:: PMC9276035

Article PDF–8.6M

Select item 65559087.

De Novo Mutations in HNRNPU Result in a Neurodevelopmental Syndrome

T Michael Yates, Pradeep Vasudevan, Kate E Chandler, Deirdre E Donnelly, Zornitza Stark, Simon Sadedin, Josh Willoughby, Broad Center for Mendelian Genomics, DDD study, Meena Balasubramanian

Am J Med Genet A. Author manuscript; available in PMC 2019 Jun 8.

Published in final edited form as: Am J Med Genet A. 2017 Nov; 173(11): 3003–3012. Published online 2017 Sep 25. doi: 10.1002/ajmg.a.38492

PMCID:: PMC6555908

Article PDF–616K

Select item 71302768.

Author Index

FEBS Lett. 2007; 581: 1–46. Published online 2007 Dec 24. doi: 10.1016/S0014-5793(07)01283-5

PMCID:: PMC7130276

Abstract PDF–627K

Select item 64962179.

Protein phosphatase 4 plays dual roles during cell proliferation

Xiuqing Huang, Jin Liu, Tao Shen, Xiangyu Meng, Lin Dou, Yajun Lin, Jian Li

Cell Prolif. 2016 Apr; 49(2): 219–235. Published online 2016 Apr 3. doi: 10.1111/cpr.12249

PMCID:: PMC6496217

Article PDF–2.7M

Select item 547394010.

SAF-A Regulates Interphase Chromosome Structure through Oligomerization with Chromatin-Associated RNAs

Ryu-Suke Nozawa, Lora Boteva, Dinesh C. Soares, Catherine Naughton, Alison R. Dun, Adam Buckle, Bernard Ramsahoye, Peter C. Bruton, Rebecca S. Saleeb, Maria Arnedo, Bill Hill, Rory R. Duncan, Sutherland K. Maciver, Nick Gilbert

Cell. 2017 Jun 15; 169(7): 1214–1227.e18. doi: 10.1016/j.cell.2017.05.029

PMCID:: PMC5473940

Article

Select item 536084411.

Genetic and phenotypic dissection of 1q43q44 microdeletion syndrome and neurodevelopmental phenotypes associated with mutations in ZBTB18 and HNRNPU

Christel Depienne, Caroline Nava, Boris Keren, Solveig Heide, Agnès Rastetter, Sandrine Passemard, Sandra Chantot-Bastaraud, Marie-Laure Moutard, Pankaj B. Agrawal, Grace VanNoy, Joan M. Stoler, David J. Amor, Thierry Billette de Villemeur, Diane Doummar, Caroline Alby, Valérie Cormier-Daire, Catherine Garel, Pauline Marzin, Sophie Scheidecker, Anne de Saint-Martin, Edouard Hirsch, Christian Korff, Armand Bottani, Laurence Faivre, Alain Verloes, Christine Orzechowski, Lydie Burglen, Bruno Leheup, Joelle Roume, Joris Andrieux, Frenny Sheth, Chaitanya Datar, Michael J. Parker, Laurent Pasquier, Sylvie Odent, Sophie Naudion, Marie-Ange Delrue, Cédric Le Caignec, Marie Vincent, Bertrand Isidor, Florence Renaldo, Fiona Stewart, Annick Toutain, Udo Koehler, Birgit Häckl, Celina von Stülpnagel, Gerhard Kluger, Rikke S. Møller, Deb Pal, Tord Jonson, Maria Soller, Nienke E. Verbeek, Mieke M. van Haelst, Carolien de Kovel, Bobby Koeleman, Glen Monroe, Gijs van Haaften, DDD Study, Tania Attié-Bitach, Lucile Boutaud, Delphine Héron, Cyril Mignot

Hum Genet. 2017; 136(4): 463–479. Published online 2017 Mar 10. doi: 10.1007/s00439-017-1772-0

PMCID:: PMC5360844

Article PDF–2.3M

Select item 534235312.

Scaffold attachment factor A (SAF-A) and Ku temporally regulate repair of radiation-induced clustered genome lesions

Muralidhar L. Hegde, Arijit Dutta, Chunying Yang, Anil K. Mantha, Pavana M. Hegde, Arvind Pandey, Shiladitya Sengupta, Yaping Yu, Patrick Calsou, David Chen, Susan P. Lees-Miller, Sankar Mitra

Oncotarget. 2016 Aug 23; 7(34): 54430–54444. Published online 2016 Jun 9. doi: 10.18632/oncotarget.9914

PMCID:: PMC5342353

Article PDF–7.0M

Select item 475554313.

Centromere Protein (CENP)-W Interacts with Heterogeneous Nuclear Ribonucleoprotein (hnRNP) U and May Contribute to Kinetochore-Microtubule Attachment in Mitotic Cells

Younghwa Chun, Raehyung Kim, Soojin Lee

PLoS One. 2016; 11(2): e0149127. Published online 2016 Feb 16. doi: 10.1371/journal.pone.0149127

PMCID:: PMC4755543

Article PDF–4.5M

Select item 346452814.

Enhancement of NEIL1 Protein-initiated Oxidized DNA Base Excision Repair by Heterogeneous Nuclear Ribonucleoprotein U (hnRNP-U) via Direct Interaction

Muralidhar L. Hegde, Srijita Banerjee, Pavana M. Hegde, Larry J. Bellot, Tapas K. Hazra, Istvan Boldogh, Sankar Mitra

J Biol Chem. 2012 Oct 5; 287(41): 34202–34211. Published online 2012 Aug 17. doi: 10.1074/jbc.M112.384032

PMCID:: PMC3464528

Article PDF–1.5M

Select item 329990515.

Nuclear Matrix Factor hnRNP U/SAF-A Exerts a Global Control of Alternative Splicing by Regulating U2 snRNP Maturation

Rui Xiao, Peng Tang, Bo Yang, Jie Huang, Yu Zhou, Changwei Shao, Hairi Li, Hui Sun, Yi Zhang, Xiang-Dong Fu

Mol Cell. Author manuscript; available in PMC 2013 Mar 9.

Published in final edited form as: Mol Cell. 2012 Mar 9; 45(5): 656–668. Published online 2012 Feb 9. doi: 10.1016/j.molcel.2012.01.009

PMCID:: PMC3299905

Article PDF–2.3M

Select item 283446116.

The Trithorax group protein Ash2l and Saf-A are recruited to the inactive X chromosome at the onset of stable X inactivation

Dieter Pullirsch, Renate Härtel, Hiroyuki Kishimoto, Martin Leeb, Günter Steiner, Anton Wutz

Development. 2010 Mar 15; 137(6): 935–943. doi: 10.1242/dev.035956

PMCID:: PMC2834461

Article

Select item 117033617.

The novel SAR-binding domain of scaffold attachment factor A (SAF-A) is a target in apoptotic nuclear breakdown.

F Göhring, B L Schwab, P Nicotera, M Leist, F O Fackelmayer

EMBO J. 1997 Dec 15; 16(24): 7361–7371. doi: 10.1093/emboj/16.24.7361

PMCID:: PMC1170336

Summary PDF–480K

Select item 55674118.

Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box.

M Kiledjian, G Dreyfuss

EMBO J. 1992 Jul; 11(7): 2655–2664. doi: 10.1002/j.1460-2075.1992.tb05331.x

PMCID:: PMC556741

Summary Page Browse PDF–3.1M

Select item 8630119.

SAF-Box, a Conserved Protein Domain That Specifically Recognizes Scaffold Attachment Region DNA

Michael Kipp, Frank Göhring, Thorsten Ostendorp, Cornelis M. van Drunen, Roel van Driel, Michael Przybylski, Frank O. Fackelmayer

Mol Cell Biol. 2000 Oct; 20(20): 7480–7489. doi: 10.1128/mcb.20.20.7480-7489.2000

PMCID:: PMC86301

Article PDF–2.1M

Select item 1031807020.

piRNA-1742 promotes renal cell carcinoma malignancy by regulating USP8 stability through binding to hnRNPU and thereby inhibiting MUC12 ubiquitination

Wentao Zhang, Zongtai Zheng, Keyi Wang, Weipu Mao, Xue Li, Guangchun Wang, Yuanyuan Zhang, Jianhua Huang, Ning Zhang, Pengfei Wu, Ji Liu, Haimin Zhang, Jianping Che, Bo Peng, Junhua Zheng, Wei Li, Xudong Yao

Exp Mol Med. 2023 Jun; 55(6): 1258–1271. Published online 2023 Jun 19. doi: 10.1038/s12276-023-01010-3

PMCID:: PMC10318070

Article PDF–8.1M

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