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Select item 85332691.

Inhibition of Astrocytic Histamine N-Methyltransferase as a Possible Target for the Treatment of Alzheimer’s Disease

Cecilia Flores-Clemente, María Inés Nicolás-Vázquez, Elvia Mera Jiménez, Maricarmen Hernández-Rodríguez

Biomolecules. 2021 Oct; 11(10): 1408. Published online 2021 Sep 26. doi: 10.3390/biom11101408

PMCID:: PMC8533269

Abstract Article PDF–2.1M

Select item 50588612.

Thr105Ile (rs11558538) polymorphism in the histamine N-methyltransferase (HNMT) gene and risk for Parkinson disease: A PRISMA-compliant systematic review and meta-analysis

Félix Javier Jiménez-Jiménez, Hortensia Alonso-Navarro, Elena García-Martín, José A.G. Agúndez

Medicine (Baltimore) 2016 Jul; 95(27): e4147. Published online 2016 Jul 8. doi: 10.1097/MD.0000000000004147

PMCID:: PMC5058861

Abstract Article PDF–576K

Select item 43590883.

Association of Histamine N-Methyltransferase Thr105Ile Polymorphism with Parkinson’s Disease and Schizophrenia in Han Chinese: A Case-Control Study

Xinglong Yang, Chuanxin Liu, Jinxiang Zhang, Hongying Han, Xiuyan Wang, Zhoulin Liu, Yanming Xu

PLoS One. 2015; 10(3): e0119692. Published online 2015 Mar 13. doi: 10.1371/journal.pone.0119692

PMCID:: PMC4359088

Abstract Article PDF–156K

Select item 41964224.

Altered Methylprednisolone Pharmacodynamics in Healthy Subjects With Histamine N-Methyltransferase C314T Genetic Polymorphism

Yuen Yi Hon, William J. Jusko, Vicky E. Spratlin, Michael W. Jann

J Clin Pharmacol. Author manuscript; available in PMC 2014 Oct 14.

Published in final edited form as: J Clin Pharmacol. 2006 Apr; 46(4): 408–417. doi: 10.1177/0091270006286434

PMCID:: PMC4196422

Abstract Article PDF–1.6M

Select item 41785295.

Endogenous Histamine and Cortisol Levels in Subjects with Different Histamine N-Methyltransferase C314T Genotypes: A Pilot Study

Yuen Yi Hon, William J. Jusko, Hong-Hao Zhou, Guo-Lin Chen, Dong Guo, Gan Zhou, Vicky E. Spratlin, Michael W. Jann

Mol Diagn Ther. Author manuscript; available in PMC 2014 Sep 29.

Published in final edited form as: Mol Diagn Ther. 2006; 10(2): 109–114. doi: 10.1007/BF03256450

PMCID:: PMC4178529

Abstract Article PDF–109K

Select item 88358566.

HNMT Upregulation Induces Cancer Stem Cell Formation and Confers Protection against Oxidative Stress through Interaction with HER2 in Non-Small-Cell Lung Cancer

Kuang-Tai Kuo, Cheng-Hsin Lin, Chun-Hua Wang, Narpati Wesa Pikatan, Vijesh Kumar Yadav, Iat-Hang Fong, Chi-Tai Yeh, Wei-Hwa Lee, Wen-Chien Huang

Int J Mol Sci. 2022 Feb; 23(3): 1663. Published online 2022 Jan 31. doi: 10.3390/ijms23031663

PMCID:: PMC8835856

Abstract Article PDF–5.9M

Select item 45816007.

Mutations in the histamine N-methyltransferase gene, HNMT, are associated with nonsyndromic autosomal recessive intellectual disability

Abolfazl Heidari, Chanakan Tongsook, Reza Najafipour, Luciana Musante, Nasim Vasli, Masoud Garshasbi, Hao Hu, Kirti Mittal, Amy J. M. McNaughton, Kumudesh Sritharan, Melissa Hudson, Henning Stehr, Saeid Talebi, Mohammad Moradi, Hossein Darvish, Muhammad Arshad Rafiq, Hossein Mozhdehipanah, Ali Rashidinejad, Shahram Samiei, Mohsen Ghadami, Christian Windpassinger, Gabriele Gillessen-Kaesbach, Andreas Tzschach, Iltaf Ahmed, Anna Mikhailov, D. James Stavropoulos, Melissa T. Carter, Soraya Keshavarz, Muhammad Ayub, Hossein Najmabadi, Xudong Liu, Hans Hilger Ropers, Peter Macheroux, John B. Vincent

Hum Mol Genet. 2015 Oct 15; 24(20): 5697–5710. Published online 2015 Jul 23. doi: 10.1093/hmg/ddv286

PMCID:: PMC4581600

Abstract Article PDF–967K

Select item 40660978.

Severity of ulcerative colitis is associated with a polymorphism at diamine oxidase gene but not at histamine N-methyltransferase gene

Elena García-Martín, Juan L Mendoza, Carmen Martínez, Carlos Taxonera, Elena Urcelay, José M Ladero, Emilio G de la Concha, Manuel Díaz-Rubio, José AG Agúndez

World J Gastroenterol. 2006 Jan 28; 12(4): 615–620. Published online 2006 Jan 28. doi: 10.3748/wjg.v12.i4.615

PMCID:: PMC4066097

Abstract Article PDF–651K

Select item 40303769.

Two Polymorphic Forms of Human Histamine Methyltransferase: Structural, Thermal, and Kinetic Comparisons

John R. Horton, Ken Sawada, Masahiro Nishibori, Xing Zhang, Xiaodong Cheng

Structure. Author manuscript; available in PMC 2014 May 22.

Published in final edited form as: Structure. 2001 Sep; 9(9): 837–849. doi: 10.1016/s0969-2126(01)00643-8

PMCID:: PMC4030376

Abstract Article PDF–1.7M

Select item 284517510.

Histamine N-methyltransferase Thr105Ile is not associated with Parkinson’s disease or essential tremor

Brett H. Keeling, Carles Vilariño-Güell, Alexandra I. Soto-Ortolaza, Owen A. Ross, Ryan J. Uitti, Alex Rajput, Zbigniew K. Wszolek, Matthew J. Farrer

Parkinsonism Relat Disord. Author manuscript; available in PMC 2011 Feb 1.

Published in final edited form as: Parkinsonism Relat Disord. 2010 Feb; 16(2): 112–114. Published online 2009 Sep 20. doi: 10.1016/j.parkreldis.2009.08.011

PMCID:: PMC2845175

Abstract Article PDF–290K

Select item 264261211.

Association of the Histamine N-methyltransferase C314T (Thr105Ile) Polymorphism with Atopic Dermatitis in Caucasian Children

Mary Jayne Kennedy, Jennifer A. Loehle, Angela R. Griffin, Mark A. Doll, Gregory L. Kearns, Janice E. Sullivan, David W. Hein

Pharmacotherapy. Author manuscript; available in PMC 2009 Feb 13.

Published in final edited form as: Pharmacotherapy. 2008 Dec; 28(12): 1495–1501. doi: 10.1592/phco.28.12.1495

PMCID:: PMC2642612

Abstract Article PDF–56K

Select item 474294012.

Genetic Variation along the Histamine Pathway in Children with Allergic versus Nonallergic Asthma

Sara Anvari, Carrie A. Vyhlidal, Hongying Dai, Bridgette L. Jones

Am J Respir Cell Mol Biol. 2015 Dec; 53(6): 802–809. doi: 10.1165/rcmb.2014-0493OC

PMCID:: PMC4742940

Abstract Article PDF–645K

Select item 402395113.

Associations of Polymorphisms in Histidine Decarboxylase, Histamine N-Methyltransferase and Histamine Receptor H₃ Genes with Breast Cancer

Gong-Hao He, Jia-Ji Lin, Wen-Ke Cai, Wen-Mang Xu, Zheng-Ping Yu, Sun-Jun Yin, Can-Hu Zhao, Gui-Li Xu

PLoS One. 2014; 9(5): e97728. Published online 2014 May 16. doi: 10.1371/journal.pone.0097728

PMCID:: PMC4023951

Abstract Article PDF–244K

Select item 299072614.

Polymorphisms of two histamine-metabolizing enzymes genes and childhood allergic asthma: a case control study

Aleksandra Szczepankiewicz, Anna Bręborowicz, Paulina Sobkowiak, Anna Popiel

Clin Mol Allergy. 2010; 8: 14. Published online 2010 Nov 1. doi: 10.1186/1476-7961-8-14

PMCID:: PMC2990726

Abstract Article PDF–224K

Select item 477351815.

Associations of Polymorphisms in HRH2, HRH3, DAO, and HNMT Genes with Risk of Chronic Heart Failure

Gong-Hao He, Wen-Ke Cai, Jia-Bin Zhang, Chao-Yu Ma, Feng Yan, Jun Lu, Gui-Li Xu

Biomed Res Int. 2016; 2016: 1208476. Published online 2016 Feb 17. doi: 10.1155/2016/1208476

PMCID:: PMC4773518

Abstract Article PDF–530K

Select item 278218816.

Polymorphisms of High-Affinity IgE Receptor and Histamine-Related Genes in Patients with ASA-Induced Urticaria/Angioedema

Jeong-Hee Choi, Seung-Hyun Kim, Chang-Hee Suh, Dong-Ho Nahm, Hae-Sim Park

J Korean Med Sci. 2005 Jun; 20(3): 367–372. Published online 2005 Jun 30. doi: 10.3346/jkms.2005.20.3.367

PMCID:: PMC2782188

Abstract Article PDF–94K

Select item 227084517.

Physiogenomic comparison of human fat loss in response to diets restrictive of carbohydrate or fat

Richard L Seip, Jeff S Volek, Andreas Windemuth, Mohan Kocherla, Maria Luz Fernandez, William J Kraemer, Gualberto Ruaño

Nutr Metab (Lond) 2008; 5: 4. Published online 2008 Feb 6. doi: 10.1186/1743-7075-5-4

PMCID:: PMC2270845

Abstract Article PDF–397K

Select item 298649918.

Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis

Anna C Need, Richard SE Keefe, Dongliang Ge, Iris Grossman, Sam Dickson, Joseph P McEvoy, David B Goldstein

Eur J Hum Genet. 2009 Jul; 17(7): 946–957. Published online 2009 Jan 21. doi: 10.1038/ejhg.2008.264

PMCID:: PMC2986499

Abstract Article PDF–172K

Select item 584108619.

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy

Samuel A. Hasson, Lesley A. Kane, Koji Yamano, Chiu-Hui Huang, Danielle A. Sliter, Eugen Buehler, Chunxin Wang, Sabrina M. Heman-Ackah, Tara Hessa, Rajarshi Guha, Scott E. Martin, Richard J. Youle

Nature. Author manuscript; available in PMC 2018 Mar 7.

Published in final edited form as: Nature. 2013 Dec 12; 504(7479): 291–295. Published online 2013 Nov 24. doi: 10.1038/nature12748

PMCID:: PMC5841086

Abstract Article PDF–5.3M

Select item 292192020.

Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?

Gualberto Ruaño, Paul D Thompson, John P Kane, Clive R Pullinger, Andreas Windemuth, Richard L Seip, Mohan Kocherla, Theodore R Holford, Alan HB Wu

Pharmacogenomics. Author manuscript; available in PMC 2011 May 1.

Published in final edited form as: Pharmacogenomics. 2010 Jul; 11(7): 959–971. doi: 10.2217/pgs.10.58

PMCID:: PMC2921920

Abstract Article PDF–1.4M

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