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Select item 111598151.

Reza Behjati, Koji Kawai, Yukinori Inadome, Junko Kano, Hideyuki Akaza, Masayuki Noguchi

Cancer Sci. 2011 Jan; 102(1): 267–274. Published online 2010 Oct 26. doi: 10.1111/j.1349-7006.2010.01750.x

PMCID:: PMC11159815

Abstract Article PDF–896K

Select item 58560892.

Apoptosome formation upon overexpression of native and truncated Apaf-1 in cell-free and cell-based systems

Ali Reza Noori, Elaheh Sadat Hosseini, Maryam Nikkhah, Saman Hosseinkhani

Arch Biochem Biophys. 2018 Mar 15; 642: 46–51. doi: 10.1016/j.abb.2018.01.017

PMCID:: PMC5856089

Abstract Article

Select item 53566383.

Aberrant localization of apoptosis protease activating factor-1 in lipid raft sub-domains of diffuse large B cell lymphomas

Jayshree L. Hirpara, Thomas Loh, Siok Bian Ng, Wee Joo Chng, Shazib Pervaiz

Oncotarget. 2016 Dec 20; 7(51): 83964–83975. Published online 2016 Nov 14. doi: 10.18632/oncotarget.13336

PMCID:: PMC5356638

Abstract Article PDF–4.9M

Select item 44455274.

Modeling of interaction between cytochrome c and the WD domains of Apaf-1: bifurcated salt bridges underlying apoptosome assembly

Daria N. Shalaeva, Daria V. Dibrova, Michael Y. Galperin, Armen Y. Mulkidjanian

Biol Direct. 2015; 10: 29. Published online 2015 May 27. doi: 10.1186/s13062-015-0059-4

PMCID:: PMC4445527

Abstract Article PDF–2.7M

Select item 44346345.

Rationales for expression and altered expression of apoptotic protease activating factor-1 gene in gastric cancer

He-Ling Wang, Han Bai, Yan Li, Jun Sun, Xue-Qing Wang

World J Gastroenterol. 2007 Oct 14; 13(38): 5060–5064. Published online 2007 Oct 14. doi: 10.3748/wjg.v13.i38.5060

PMCID:: PMC4434634

Abstract Article PDF–1.0M

Select item 39670756.

High expression of APAF-1 elevates erythroid apoptosis in iron overload myelodysplastic syndrome

Shucheng Gu, Youshan Zhao, Juan Guo, Feng Xu, Chengming Fei, Xi Zhang, Chao Xiao, Chunkang Chang, Xiao Li

Tumour Biol. 2014 Mar; 35(3): 2211–2218. Published online 2013 Oct 19. doi: 10.1007/s13277-013-1294-x

PMCID:: PMC3967075

Abstract Article PDF–679K

Select item 37525177.

Modulating Roles of Amiloride in Irradiation-Induced Antiproliferative Effects in Glioblastoma Multiforme Cells Involving Akt Phosphorylation and the Alternative Splicing of Apoptotic Genes

Jen-Yang Tang, Hsueh-Wei Chang, Jan-Gowth Chang

DNA Cell Biol. 2013 Sep; 32(9): 504–510. doi: 10.1089/dna.2013.1998

PMCID:: PMC3752517

Abstract Article PDF–362K

Select item 36459208.

Changes in Apaf-1 conformation that drive apoptosome assembly

Shujun Yuan, Maya Topf, Thomas F. Reubold, Susanne Eschenburg, Christopher W. Akey

Biochemistry. Author manuscript; available in PMC 2014 Apr 2.

Published in final edited form as: Biochemistry. 2013 Apr 2; 52(13): 2319–2327. Published online 2013 Mar 22. doi: 10.1021/bi301721g

PMCID:: PMC3645920

Abstract Article PDF–8.4M

Select item 35801679.

A Sequencing-Based Survey of Functional APAF1 Alleles in a Large Sample of Individuals with Affective Illness and Population Controls

Zenab Amin, Katarzyna Kanarek, Evgeny Krupitsky, Espen Walderhaug, Risto Ilomäki, Hilary Blumberg, Lawrence H. Price, Zubin Bhagwagar, Linda L. Carpenter, Audrey R. Tyrka, Andres Magnusson, Nils Inge Landrø, Edwin Zvartau, Joel Gelernter, C. Neill Epperson, Pirkko Räsänen, Jari Siironen, Jaakko Lappalainen

Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2013 Feb 24.

Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2010 Jan 5; 153B(1): 332–335. doi: 10.1002/ajmg.b.30984

PMCID:: PMC3580167

Abstract Article PDF–284K

Select item 278168810.

A New Model for the Transition of APAF-1 from Inactive Monomer to Caspase-activating Apoptosome

Thomas F. Reubold, Sabine Wohlgemuth, Susanne Eschenburg

J Biol Chem. 2009 Nov 20; 284(47): 32717–32724. Published online 2009 Sep 30. doi: 10.1074/jbc.M109.014027

PMCID:: PMC2781688

Abstract Article PDF–1.3M

Select item 274770511.

Reduced Apaf-1 expression in human cutaneous melanomas

D L Dai, M Martinka, J A Bush, G Li

Br J Cancer. 2004 Sep 13; 91(6): 1089–1095. Published online 2004 Aug 10. doi: 10.1038/sj.bjc.6602092

PMCID:: PMC2747705

Abstract Article PDF–182K

Select item 236076212.

Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer

F Christoph, C Kempkensteffen, S Weikert, J Köllermann, H Krause, K Miller, M Schostak, M Schrader

Br J Cancer. 2006 Dec 18; 95(12): 1701–1707. Published online 2006 Nov 28. doi: 10.1038/sj.bjc.6603482

PMCID:: PMC2360762

Abstract Article PDF–114K

Select item 219382813.

The Apoptosome Pathway to Caspase Activation in Primary Human Neutrophils Exhibits Dramatically Reduced Requirements for Cytochrome c

Brona M. Murphy, Amanda J. O'Neill, Colin Adrain, R. William G. Watson, Seamus J. Martin

J Exp Med. 2003 Mar 3; 197(5): 625–632. doi: 10.1084/jem.20021862

PMCID:: PMC2193828

Abstract Article PDF–319K

Select item 117143714.

Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis.

Y Hu, M A Benedict, L Ding, G Núñez

EMBO J. 1999 Jul 1; 18(13): 3586–3595. doi: 10.1093/emboj/18.13.3586

PMCID:: PMC1171437

Summary PDF–290K

Select item 1013900615.

Upregulation of APAF1 and CSF1R in Peripheral Blood Mononuclear Cells of Parkinson’s Disease

Kuo-Hsuan Chang, Chia-Hsin Liu, Yi-Ru Wang, Yen-Shi Lo, Chun-Wei Chang, Hsiu-Chuan Wu, Chiung-Mei Chen

Int J Mol Sci. 2023 Apr; 24(8): 7095. Published online 2023 Apr 12. doi: 10.3390/ijms24087095

PMCID:: PMC10139006

Abstract Article PDF–621K

Select item 953496716.

APAF1‐Binding Long Noncoding RNA Promotes Tumor Growth and Multidrug Resistance in Gastric Cancer by Blocking Apoptosome Assembly

Qiang Wang, Chen Chen, Xiao Xu, Chuanjun Shu, Changchang Cao, Zhangding Wang, Yao Fu, Lei Xu, Kaiyue Xu, Jiawen Xu, Anliang Xia, Bo Wang, Guifang Xu, Xiaoping Zou, Ruibao Su, Wei Kang, Yuanchao Xue, Ran Mo, Beicheng Sun, Shouyu Wang

Adv Sci (Weinh) 2022 Oct; 9(28): 2201889. Published online 2022 Aug 17. doi: 10.1002/advs.202201889

PMCID:: PMC9534967

Abstract Article PDF–10M

Select item 880597017.

Exosomal microRNA⁃93⁃3p secreted by bone marrow mesenchymal stem cells downregulates apoptotic peptidase activating factor 1 to promote wound healing

Caiqi Shen, Changbo Tao, Aijun Zhang, Xueyang Li, Yanping Guo, Hanxiao Wei, Qichuan Yin, Qiang Li, Peisheng Jin

Bioengineered. 2022; 13(1): 27–37. Published online 2021 Dec 24. doi: 10.1080/21655979.2021.1997077

PMCID:: PMC8805970

Abstract Article PDF–3.0M

Select item 790459718.

Intracellular leucine-rich alpha-2-glycoprotein-1 competes with Apaf-1 for binding cytochrome c in protecting MCF-7 breast cancer cells from apoptosis

Ronald Jemmerson, Katherine Staskus, LeeAnn Higgins, Kathleen Conklin, Ameeta Kelekar

Apoptosis. Author manuscript; available in PMC 2022 Feb 1.

Published in final edited form as: Apoptosis. 2021 Feb; 26(1-2): 71–82. Published online 2021 Jan 1. doi: 10.1007/s10495-020-01647-9

PMCID:: PMC7904597

Abstract Article PDF–1.6M

Select item 710900319.

Hypoxia-induced up-regulation of miR-27a promotes paclitaxel resistance in ovarian cancer

Lanlan Feng, Fangrong Shen, Jinhua Zhou, Yan Li, Rong Jiang, Youguo Chen

Biosci Rep. 2020 Apr 30; 40(4): BSR20192457. Published online 2020 Mar 31. doi: 10.1042/BSR20192457

PMCID:: PMC7109003

Abstract Article PDF–1.4M

Select item 659984020.

Circular RNA Cdr1as sensitizes bladder cancer to cisplatin by upregulating APAF1 expression through miR‐1270 inhibition

Wenbo Yuan, Rui Zhou, Jingzi Wang, Jie Han, Xiao Yang, Hao Yu, Hongcheng Lu, Xiaolei Zhang, Pengchao Li, Jun Tao, Jifu Wei, Qiang Lu, Haiwei Yang, Min Gu

Mol Oncol. 2019 Jul; 13(7): 1559–1576. Published online 2019 Jun 9. doi: 10.1002/1878-0261.12523

PMCID:: PMC6599840

Abstract Article PDF–3.1M

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PMC Links for Gene (Select 317) (84)
PMC
Homo sapiens ubiquitin specific peptidase 36 (USP36), transcript variant 12, mRN...
Homo sapiens ubiquitin specific peptidase 36 (USP36), transcript variant 12, mRNA
gi|1867163781|ref|NM_001385179.1|

Nucleotide
PREDICTED: Homo sapiens jade family PHD finger 2 (JADE2), transcript variant X14...
PREDICTED: Homo sapiens jade family PHD finger 2 (JADE2), transcript variant X14, mRNA
gi|2462601788|ref|XM_054352232.1|

Nucleotide
APAF1[gene] (84)
ClinVar
60S acidic ribosomal protein P1 [Seriola dumerili]
60S acidic ribosomal protein P1 [Seriola dumerili]
gi|1250124253|ref|XP_022603461.1|

Protein

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