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Select item 34081361.

The Actin Regulatory Protein HS1 Interacts with Arp2/3 and Mediates Efficient Neutrophil Chemotaxis

Peter J. Cavnar, Kevin Mogen, Erwin Berthier, David J. Beebe, Anna Huttenlocher

J Biol Chem. 2012 Jul 20; 287(30): 25466–25477. Published online 2012 Jun 7. doi: 10.1074/jbc.M112.364562

PMCID:: PMC3408136

Abstract Article PDF–2.5M

Select item 33872322.

HS1, a Lyn Kinase Substrate, Is Abnormally Expressed in B-Chronic Lymphocytic Leukemia and Correlates with Response to Fludarabine-Based Regimen

Federica Frezzato, Cristina Gattazzo, Veronica Martini, Valentina Trimarco, Antonella Teramo, Samuela Carraro, Anna Cabrelle, Elisa Ave, Monica Facco, Renato Zambello, Elena Tibaldi, Anna Maria Brunati, Gianpietro Semenzato, Livio Trentin

PLoS One. 2012; 7(6): e39902. Published online 2012 Jun 29. doi: 10.1371/journal.pone.0039902

PMCID:: PMC3387232

Abstract Article PDF–661K

Select item 3351383.

Isolation and characterization of a novel human gene expressed specifically in the cells of hematopoietic lineage.

D Kitamura, H Kaneko, Y Miyagoe, T Ariyasu, T Watanabe

Nucleic Acids Res. 1989 Nov 25; 17(22): 9367–9379.

PMCID:: PMC335138

Summary Page Browse PDF–1.7M

Select item 5541004.

Comparative genome analysis of cortactin and HS1: the significance of the F-actin binding repeat domain

Agnes GSH van Rossum, Ellen Schuuring-Scholtes, Vera van Buuren-van Seggelen, Philip M Kluin, Ed Schuuring

BMC Genomics. 2005; 6: 15. Published online 2005 Feb 14. doi: 10.1186/1471-2164-6-15

PMCID:: PMC554100

Abstract Article PDF–395K

Select item 56700285.

Wnt5a induces ROR1 to complex with HS1 to enhance migration of chronic lymphocytic leukemia cells

M K Hasan, J Yu, L Chen, Bing Cui, G F Widhopf II, L Rassenti, Z Shen, S P Briggs, T J Kipps

Leukemia. 2017 Dec; 31(12): 2615–2622. Prepublished online 2017 May 3. Published online 2017 Jun 16. doi: 10.1038/leu.2017.133

PMCID:: PMC5670028

Abstract Article PDF–1.3M

Select item 44367766.

The C-terminus SH3-binding domain of Kv1.3 is required for the actin-mediated immobilization of the channel via cortactin

Peter Hajdu, Geoffrey V. Martin, Ameet A. Chimote, Orsolya Szilagyi, Koichi Takimoto, Laura Conforti

Mol Biol Cell. 2015 May 1; 26(9): 1640–1651. doi: 10.1091/mbc.E14-07-1195

PMCID:: PMC4436776

Abstract Article PDF–4.9M

Select item 21962527.

Role of Tyrosine Phosphorylation of HS1 in B Cell Antigen Receptor-mediated Apoptosis

Yuji Yamanashi, Takahiro Fukuda, Hirofumi Nishizumi, Tetsuya Inazu, Ken-ichi Higashi, Daisuke Kitamura, Takaomi Ishida, Hirohei Yamamura, Takeshi Watanabe, Tadashi Yamamoto

J Exp Med. 1997 Apr 7; 185(7): 1387–1392. doi: 10.1084/jem.185.7.1387

PMCID:: PMC2196252

Abstract Article PDF–150K

Select item 12225438.

Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells.

Maria Ruzzene, Daniele Penzo, Lorenzo A Pinna

Biochem J. 2002 May 15; 364(Pt 1): 41–47. doi: 10.1042/bj3640041

PMCID:: PMC1222543

Summary PDF–180K

Select item 463559.

Identification of HS1 protein as a major substrate of protein-tyrosine kinase(s) upon B-cell antigen receptor-mediated signaling.

Y Yamanashi, M Okada, T Semba, T Yamori, H Umemori, S Tsunasawa, K Toyoshima, D Kitamura, T Watanabe, T Yamamoto

Proc Natl Acad Sci U S A. 1993 Apr 15; 90(8): 3631–3635. doi: 10.1073/pnas.90.8.3631

PMCID:: PMC46355

Summary Page Browse PDF–1.5M

Select item 346710610.

Hematopoietic Lineage Cell-Specific Protein 1 Functions in Concert with the Wiskott–Aldrich Syndrome Protein To Promote Podosome Array Organization and Chemotaxis in Dendritic Cells

Deborah A. Klos Dehring, Fiona Clarke, Brendon G. Ricart, Yanping Huang, Timothy S. Gomez, Edward K. Williamson, Daniel A. Hammer, Daniel D. Billadeau, Yair Argon, Janis K. Burkhardt

J Immunol. Author manuscript; available in PMC 2012 Oct 9.

Published in final edited form as: J Immunol. 2011 Apr 15; 186(8): 4805–4818. Published online 2011 Mar 11. doi: 10.4049/jimmunol.1003102

PMCID:: PMC3467106

Abstract Article PDF–2.8M

Select item 122330911.

Haematopoietic lineage cell-specific protein 1 (HS1) promotes actin-related protein (Arp) 2/3 complex-mediated actin polymerization.

Takehito Uruno, Peijun Zhang, Jiali Liu, Jian-Jiang Hao, Xi Zhan

Biochem J. 2003 Apr 15; 371(Pt 2): 485–493. doi: 10.1042/BJ20021791

PMCID:: PMC1223309

Summary PDF–304K

Select item 394191812.

Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF–triggered granulopoiesis

Julia Skokowa, Maxim Klimiankou, Olga Klimenkova, Dan Lan, Kshama Gupta, Kais Hussein, Esteban Carrizosa, Inna Kusnetsova, Zhixiong Li, Claudio Sustmann, Arnold Ganser, Cornelia Zeidler, Hans-Heinrich Kreipe, Janis Burkhardt, Rudolf Grosschedl, Karl Welte

Nat Med. Author manuscript; available in PMC 2014 Mar 4.

Published in final edited form as: Nat Med. 2012 Oct; 18(10): 1550–1559. Published online 2012 Sep 23. doi: 10.1038/nm.2958

PMCID:: PMC3941918

Abstract Article PDF–2.6M

Select item 14101413.

Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry

Arthur R. Salomon, Scott B. Ficarro, Laurence M. Brill, Achim Brinker, Qui T. Phung, Christer Ericson, Karsten Sauer, Ansgar Brock, David M. Horn, Peter G. Schultz, Eric C. Peters

Proc Natl Acad Sci U S A. 2003 Jan 21; 100(2): 443–448. Published online 2003 Jan 9. doi: 10.1073/pnas.2436191100

PMCID:: PMC141014

Abstract Article PDF–152K

Select item 389378314.

Identification of proteins that interact with alpha A-crystallin using a human proteome microarray

Qi Fan, Lv-Zhen Huang, Xiang-Jia Zhu, Ke-Ke Zhang, Hong-Fei Ye, Yi Luo, Xing-Huai Sun, Peng Zhou, Yi Lu

Mol Vis. 2014; 20: 117–124. Published online 2014 Jan 14.

PMCID:: PMC3893783

Abstract Article PDF–1024K

Select item 359599015.

NOTCH1 Nuclear Interactome Reveals Key Regulators of Its Transcriptional Activity and Oncogenic Function

Ahmad Yatim, Clarisse Benne, Bijan Sobhian, Sabine Laurent-Chabalier, Olivier Deas, Jean-Gabriel Judde, Jean-Daniel Lelievre, Yves Levy, Monsef Benkirane

Mol Cell. Author manuscript; available in PMC 2013 Mar 13.

Published in final edited form as: Mol Cell. 2012 Nov 9; 48(3): 445–458. Published online 2012 Sep 27. doi: 10.1016/j.molcel.2012.08.022

PMCID:: PMC3595990

Abstract Article PDF–3.9M

Select item 671971816.

Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens

Michael S. Haney, Christopher J. Bohlen, David W Morgens, James A. Ousey, Amira A. Barkal, C. Kimberly Tsui, Braeden Ego, Roni Levin, Roarke Kamber, Hannah Collins, Andrew Tucker, Amy Li, Daan Vorselen, Lorenzo Labitigan, Emily Crane, Evan Boyle, Lihua Jiang, Joanne Chan, Esther Rincón, William J. Greenleaf, Billy Li, Michael P. Snyder, Irving L. Weissman, Julie A. Theriot, Sean R. Collins, Ben A. Barres, Michael C. Bassik

Nat Genet. Author manuscript; available in PMC 2019 Sep 3.

Published in final edited form as: Nat Genet. 2018 Dec; 50(12): 1716–1727. Published online 2018 Nov 5. doi: 10.1038/s41588-018-0254-1

PMCID:: PMC6719718

Abstract Article PDF–1.3M

Select item 676993017.

Endoglin Protein Interactome Profiling Identifies TRIM21 and Galectin-3 as New Binding Partners

Eunate Gallardo-Vara, Lidia Ruiz-Llorente, Juan Casado-Vela, María J. Ruiz-Rodríguez, Natalia López-Andrés, Asit K. Pattnaik, Miguel Quintanilla, Carmelo Bernabeu

Cells. 2019 Sep; 8(9): 1082. Published online 2019 Sep 13. doi: 10.3390/cells8091082

PMCID:: PMC6769930

Abstract Article PDF–4.3M

Select item 603071918.

CRISPR/Cas9-mediated Genomic Editing of Cluap1/IFT38 Reveals a New Role in Actin Arrangement

Tina Beyer, Sylvia Bolz, Katrin Junger, Nicola Horn, Muhammad Moniruzzaman, Yasmin Wissinger, Marius Ueffing, Karsten Boldt

Mol Cell Proteomics. 2018 Jul; 17(7): 1285–1294. Published online 2018 Apr 3. doi: 10.1074/mcp.RA117.000487

PMCID:: PMC6030719

Abstract Article PDF–2.7M

Select item 671347519.

Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance

Matthew F Pech, Linda E Fong, Jacqueline E Villalta, Leanne JG Chan, Samir Kharbanda, Jonathon J O'Brien, Fiona E McAllister, Ari J Firestone, Calvin H Jan, Jeffrey Settleman

eLife. 2019; 8: e47362. Published online 2019 Aug 27. doi: 10.7554/eLife.47362

PMCID:: PMC6713475

Abstract Article PDF–4.6M

Select item 467168320.

The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells

Thomas C. Whisenant, Eigen R. Peralta, Lauren D. Aarreberg, Nina J. Gao, Steven R. Head, Phillip Ordoukhanian, Jamie R. Williamson, Daniel R. Salomon

PLoS One. 2015; 10(12): e0144409. Published online 2015 Dec 7. doi: 10.1371/journal.pone.0144409

PMCID:: PMC4671683

Abstract Article PDF–6.2M

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