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Items: 1 to 20 of 79

1.
Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression
Siddhant U. Jain, Sima Khazaei, Dylan M. Marchione, Stefan M. Lundgren, Xiaoshi Wang, Daniel N. Weinberg, Shriya Deshmukh, Nikoleta Juretic, Chao Lu, C. David Allis, Benjamin A. Garcia, Nada Jabado, Peter W. Lewis
Proc Natl Acad Sci U S A. 2020 Nov 3; 117(44): 27354–27364. Published online 2020 Oct 16. doi: 10.1073/pnas.2006076117
PMCID:
PMC7959516
AbstractArticlePDF–1.9M
2.
Validation of a microRNA target site polymorphism in H3F3B that is potentially associated with a broad schizophrenia phenotype
William Manley, Michael P. Moreau, Marco Azaro, Stephen K. Siecinski, Gillian Davis, Steven Buyske, Veronica Vieland, Anne S. Bassett, Linda Brzustowicz
PLoS One. 2018; 13(3): e0194233. Published online 2018 Mar 12. doi: 10.1371/journal.pone.0194233
PMCID:
PMC5847241
AbstractArticlePDF–1.1M
3.
Probe the function of histone lysine 36 methylation using histone H3 lysine 36 to methionine mutant transgene in mammalian cells
Dong Fang, Haiyun Gan, Heping Wang, Hui Zhou, Zhiguo Zhang
Cell Cycle. 2017; 16(19): 1781–1789. Published online 2017 Jan 27. doi: 10.1080/15384101.2017.1281483
PMCID:
PMC5628648
AbstractArticlePDF–846K
4.
Pediatric glioma histone H3.3 K27M/G34R mutations drive abnormalities in PML nuclear bodies
Hsiao P. J. Voon, Linda Hii, Andrew Garvie, Maheshi Udugama, Brian Krug, Caterina Russo, Anderly C. Chüeh, Roger J. Daly, Alison Morey, Toby D. M. Bell, Stephen J. Turner, Joseph Rosenbluh, Paul Daniel, Ron Firestein, Jeffrey R. Mann, Philippe Collas, Nada Jabado, Lee H. Wong
Genome Biol. 2023; 24: 284. Published online 2023 Dec 8. doi: 10.1186/s13059-023-03122-5
PMCID:
PMC10704828
AbstractArticlePDF–5.8M
5.
De novo variants in H3-3A and H3-3B are associated with neurodevelopmental delay, dysmorphic features, and structural brain abnormalities
Volkan Okur, Zefu Chen, Liesbeth Vossaert, Sandra Peacock, Jill Rosenfeld, Lina Zhao, Haowei Du, Emily Calamaro, Amanda Gerard, Sen Zhao, Jill Kelsay, Ashley Lahr, Chloe Mighton, Hillary M. Porter, Amy Siemon, Josh Silver, Shayna Svihovec, Chin-To Fong, Christina L. Grant, Jordan Lerner-Ellis, Kandamurugu Manickam, Suneeta Madan-Khetarpal, Shawn E. McCandless, Chantal F. Morel, G. Bradley Schaefer, Elizabeth M. Berry-Kravis, Ryan Gates, Natalia Gomez-Ospina, Guixing Qiu, Terry Jianguo Zhang, Zhihong Wu, Linyan Meng, Pengfei Liu, Daryl A. Scott, James R. Lupski, Christine M. Eng, Nan Wu, Bo Yuan
NPJ Genom Med. 2021; 6: 104. Published online 2021 Dec 7. doi: 10.1038/s41525-021-00268-8
PMCID:
PMC8651650
AbstractArticlePDF–1.7M
6.
RNF8 mediates histone H3 ubiquitylation and promotes glycolysis and tumorigenesis
Yan Xia, Weiwei Yang, Ming Fa, Xinjian Li, Yugang Wang, Yuhui Jiang, Yanhua Zheng, Jong-Ho Lee, Jing Li, Zhimin Lu
J Exp Med. 2017 Jun 5; 214(6): 1843–1855. doi: 10.1084/jem.20170015
PMCID:
PMC5461008
AbstractArticlePDF–1.6M
7.
Distinct H3F3A and H3F3B driver variants define chondroblastoma and giant cell tumour of bone
Sam Behjati, Patrick S Tarpey, Nadège Presneau, Susanne Scheipl, Nischalan Pillay, Peter Van Loo, David C Wedge, Susanna L Cooke, Gunes Gundem, Helen Davies, Serena Nik-Zainal, Sancha Martin, Stuart McLaren, Victoria Goodie, Ben Robinson, Adam Butler, Jon W Teague, Dina Halai, Bhavisha Khatri, Ola Myklebost, Daniel Baumhoer, Gernot Jundt, Rifat Hamoudi, Roberto Tirabosco, M Fernanda Amary, P Andrew Futreal, Michael R Stratton, Peter J Campbell, Adrienne M Flanagan
Nat Genet. Author manuscript; available in PMC 2013 Dec 1.
Published in final edited form as: Nat Genet. 2013 Dec; 45(12): 10.1038/ng.2814. Published online 2013 Oct 27. doi: 10.1038/ng.2814
Correction in:
volume 46 on page 316
PMCID:
PMC3839851
AbstractArticlePDF–297K
8.
Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX–DNMT3–DNMT3L domain
Junji Otani, Toshiyuki Nankumo, Kyohei Arita, Susumu Inamoto, Mariko Ariyoshi, Masahiro Shirakawa
EMBO Rep. 2009 Nov; 10(11): 1235–1241. Published online 2009 Oct 16. doi: 10.1038/embor.2009.218
PMCID:
PMC2775176
AbstractArticlePDF–1.1M
9.
Histone H3.3 beyond cancer: Germline mutations in Histone 3 Family 3A and 3B cause a previously unidentified neurodegenerative disorder in 46 patients
Laura Bryant, Dong Li, Samuel G. Cox, Dylan Marchione, Evan F. Joiner, Khadija Wilson, Kevin Janssen, Pearl Lee, Michael E. March, Divya Nair, Elliott Sherr, Brieana Fregeau, Klaas J. Wierenga, Alexandrea Wadley, Grazia M. S. Mancini, Nina Powell-Hamilton, Jiddeke van de Kamp, Theresa Grebe, John Dean, Alison Ross, Heather P. Crawford, Zoe Powis, Megan T. Cho, Marcia C. Willing, Linda Manwaring, Rachel Schot, Caroline Nava, Alexandra Afenjar, Davor Lessel, Matias Wagner, Thomas Klopstock, Juliane Winkelmann, Claudia B. Catarino, Kyle Retterer, Jane L. Schuette, Jeffrey W. Innis, Amy Pizzino, Sabine Lüttgen, Jonas Denecke, Tim M. Strom, Kristin G. Monaghan, DDD Study, Zuo-Fei Yuan, Holly Dubbs, Renee Bend, Jennifer A. Lee, Michael J. Lyons, Julia Hoefele, Roman Günthner, Heiko Reutter, Boris Keren, Kelly Radtke, Omar Sherbini, Cameron Mrokse, Katherine L. Helbig, Sylvie Odent, Benjamin Cogne, Sandra Mercier, Stephane Bezieau, Thomas Besnard, Sebastien Kury, Richard Redon, Karit Reinson, Monica H. Wojcik, Katrin Õunap, Pilvi Ilves, A. Micheil Innes, Kristin D. Kernohan, Care4Rare Canada Consortium, Gregory Costain, M. Stephen Meyn, David Chitayat, Elaine Zackai, Anna Lehman, Hilary Kitson, CAUSES Study, Martin G. Martin, Julian A. Martinez-Agosto, Undiagnosed Diseases Network, Stan F. Nelson, Christina G. S. Palmer, Jeanette C. Papp, Neil H. Parker, Janet S. Sinsheimer, Eric Vilain, Jijun Wan, Amanda J. Yoon, Allison Zheng, Elise Brimble, Giovanni Battista Ferrero, Francesca Clementina Radio, Diana Carli, Sabina Barresi, Alfredo Brusco, Marco Tartaglia, Jennifer Muncy Thomas, Luis Umana, Marjan M. Weiss, Garrett Gotway, K. E. Stuurman, Michelle L. Thompson, Kirsty McWalter, Constance T. R. M. Stumpel, Servi J. C. Stevens, Alexander P. A. Stegmann, Kristian Tveten, Arve Vøllo, Trine Prescott, Christina Fagerberg, Lone Walentin Laulund, Martin J. Larsen, Melissa Byler, Robert Roger Lebel, Anna C. Hurst, Joy Dean, Samantha A. Schrier Vergano, Jennifer Norman, Saadet Mercimek-Andrews, Juanita Neira, Margot I. Van Allen, Nicola Longo, Elizabeth Sellars, Raymond J. Louie, Sara S. Cathey, Elly Brokamp, Delphine Heron, Molly Snyder, Adeline Vanderver, Celeste Simon, Xavier de la Cruz, Natália Padilla, J. Gage Crump, Wendy Chung, Benjamin Garcia, Hakon H. Hakonarson, Elizabeth J. Bhoj
Sci Adv. 2020 Dec; 6(49): eabc9207. Published online 2020 Dec 2. doi: 10.1126/sciadv.abc9207
PMCID:
PMC7821880
AbstractArticlePDF–709K
10.
H3.3/H2A.Z double variant-containing nucleosomes mark ‘nucleosome-free regions’ of active promoters and other regulatory regions in the human genome
Chunyuan Jin, Chongzhi Zang, Gang Wei, Kairong Cui, Weiqun Peng, Keji Zhao, Gary Felsenfeld
Nat Genet. Author manuscript; available in PMC 2011 Jun 29.
Published in final edited form as: Nat Genet. 2009 Aug; 41(8): 941–945. Published online 2009 Jul 26. doi: 10.1038/ng.409
PMCID:
PMC3125718
AbstractArticlePDF–984K
11.
The PZP domain of AF10 senses unmodified H3K27 to regulate DOT1L-mediated methylation of H3K79
Shoudeng Chen, Ze Yang, Alex W. Wilkinson, Aniruddha J. Deshpande, Simone Sidoli, Krzysztof Krajewski, Brian D. Strahl, Benjamin A. Garcia, Scott A. Armstrong, Dinshaw J. Patel, Or Gozani
Mol Cell. Author manuscript; available in PMC 2016 Oct 15.
Published in final edited form as: Mol Cell. 2015 Oct 15; 60(2): 319–327. Published online 2015 Oct 1. doi: 10.1016/j.molcel.2015.08.019
PMCID:
PMC4609290
AbstractArticlePDF–1.3M
12.
PELP1 is a reader of histone H3 methylation that facilitates oestrogen receptor-α target gene activation by regulating lysine demethylase 1 specificity
Sujit S Nair, Binoj C Nair, Valerie Cortez, Dimple Chakravarty, Eric Metzger, Roland Schüle, Darrell W Brann, Rajeshwar R Tekmal, Ratna K Vadlamudi
EMBO Rep. 2010 Jun; 11(6): 438–444. Published online 2010 May 7. doi: 10.1038/embor.2010.62
PMCID:
PMC2892318
AbstractArticlePDF–614K
13.
Methylation at arginine 17 of histone H3 is linked to gene activation
Uta-Maria Bauer, Sylvain Daujat, Søren J. Nielsen, Karl Nightingale, Tony Kouzarides
EMBO Rep. 2002 Jan 15; 3(1): 39–44. doi: 10.1093/embo-reports/kvf013
PMCID:
PMC1083932
AbstractArticlePDF–326K
14.
Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres
Peter W. Lewis, Simon J. Elsaesser, Kyung-Min Noh, Sonja C. Stadler, C. David Allis
Proc Natl Acad Sci U S A. 2010 Aug 10; 107(32): 14075–14080. Published online 2010 Jul 22. doi: 10.1073/pnas.1008850107
PMCID:
PMC2922592
AbstractArticlePDF–1.3M
15.
Distinct factors control histone variant H3.3 localization at specific genomic regions
Aaron D. Goldberg, Laura A. Banaszynski, Kyung-Min Noh, Peter W. Lewis, Simon J. Elsaesser, Sonja Stadler, Scott Dewell, Martin Law, Xingyi Guo, Xuan Li, Duancheng Wen, Ariane Chapgier, Russell C. DeKelver, Jeffrey C. Miller, Ya-Li Lee, Elizabeth A. Boydston, Michael C. Holmes, Philip D. Gregory, John M. Greally, Shahin Rafii, Chingwen Yang, Peter J. Scambler, David Garrick, Richard J. Gibbons, Douglas R. Higgs, Ileana M. Cristea, Fyodor D. Urnov, Deyou Zheng, C. David Allis
Cell. Author manuscript; available in PMC 2011 Mar 5.
Published in final edited form as: Cell. 2010 Mar 5; 140(5): 678–691. doi: 10.1016/j.cell.2010.01.003
PMCID:
PMC2885838
AbstractArticlePDF–3.6M
16.
ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells
Lee H. Wong, James D. McGhie, Marcus Sim, Melissa A. Anderson, Soyeon Ahn, Ross D. Hannan, Amee J. George, Kylie A. Morgan, Jeffrey R. Mann, K.H. Andy Choo
Genome Res. 2010 Mar; 20(3): 351–360. doi: 10.1101/gr.101477.109
PMCID:
PMC2840985
AbstractArticlePDF–1.4M
17.
A phospho/methyl switch at histone H3 regulates TFIID association with mitotic chromosomes
Radhika A Varier, Nikolay S Outchkourov, Petra de Graaf, Frederik M A van Schaik, Henk Jan L Ensing, Fangwei Wang, Jonathan M G Higgins, Geert J P L Kops, HTh Marc Timmers
EMBO J. 2010 Dec 1; 29(23): 3967–3978. Published online 2010 Oct 15. doi: 10.1038/emboj.2010.261
PMCID:
PMC3020634
AbstractArticlePDF–1.1M
18.
Histone modifications defining active genes persist after transcriptional and mitotic inactivation
Antigone Kouskouti, Iannis Talianidis
EMBO J. 2005 Jan 26; 24(2): 347–357. Published online 2004 Dec 16. doi: 10.1038/sj.emboj.7600516
PMCID:
PMC545808
AbstractArticlePDF–448K
19.
ZMYND11 links histone H3.3 K36 trimethylation to transcription elongation and tumor suppression
Hong Wen, Yuanyuan Li, Yuanxin Xi, Shiming Jiang, Sabrina Stratton, Danni Peng, Kaori Tanaka, Yongfeng Ren, Zheng Xia, Jun Wu, Bing Li, Michelle C. Barton, Wei Li, Haitao Li, Xiaobing Shi
Nature. Author manuscript; available in PMC 2014 Oct 10.
Published in final edited form as: Nature. 2014 Apr 10; 508(7495): 263–268. Published online 2014 Mar 2. doi: 10.1038/nature13045
PMCID:
PMC4142212
AbstractArticlePDF–2.5M
20.
A Cul4 E3 ubiquitin ligase regulates histone hand-off during nucleosome assembly
Junhong Han, Hui Zhang, Honglian Zhang, Zhiquan Wang, Hui Zhou, Zhiguo Zhang
Cell. Author manuscript; available in PMC 2014 Nov 7.
Published in final edited form as: Cell. 2013 Nov 7; 155(4): 817–829. doi: 10.1016/j.cell.2013.10.014
PMCID:
PMC3994564
AbstractArticlePDF–2.2M

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