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Items: 13

1.
TBK1 regulates regeneration of pancreatic β-cells
Yun-Fang Jia, Subbiah Jeeva, Jin Xu, Carrie Jo Heppelmann, Jin Sung Jang, Michael Q. Slama, Subhasish Tapadar, Adegboyega K. Oyelere, Sang-Moo Kang, Aleksey V. Matveyenko, Quinn P. Peterson, Chong Hyun Shin
Sci Rep. 2020; 10: 19374. Published online 2020 Nov 9. doi: 10.1038/s41598-020-76600-6
PMCID:
PMC7653919
AbstractArticlePDF–5.2M
2.
Mutant p53R211* ameliorates inflammatory arthritis in AIA rats via inhibition of TBK1-IRF3 innate immune response
Yaling Zeng, Jerome P. L. Ng, Linna Wang, Xiongfei Xu, Betty Yuen Kwan Law, Guobing Chen, Hang Hong Lo, Lijun Yang, Jiujie Yang, Lei Zhang, Liqun Qu, Xiaoyun Yun, Jing Zhong, Ruihong Chen, Dingqi Zhang, Yuping Wang, Weidan Luo, Congling Qiu, Baixiong Huang, Wenfeng liu, Liang Liu, Vincent Kam Wai Wong
Inflamm Res. 2023; 72(12): 2199–2219. Published online 2023 Nov 8. doi: 10.1007/s00011-023-01809-w
PMCID:
PMC10656327
AbstractArticlePDF–13M
3.
TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models
Ramanath Narayana Hegde, Anass Chiki, Lara Petricca, Paola Martufi, Nicolas Arbez, Laurent Mouchiroud, Johan Auwerx, Christian Landles, Gillian P Bates, Malvindar K Singh‐Bains, Mike Dragunow, Maurice A Curtis, Richard LM Faull, Christopher A Ross, Andrea Caricasole, Hilal A Lashuel
EMBO J. 2020 Sep 1; 39(17): e104671. Published online 2020 Aug 5. doi: 10.15252/embj.2020104671
PMCID:
PMC7459410
AbstractArticlePDF–3.0M
4.
Structural Insights into the Functions of TBK1 in Innate Antimicrobial Immunity
Chang Shu, Banumathi Sankaran, Catherine T. Chaton, Andrew B. Herr, Ashutosh Mishra, Junmin Peng, Pingwei Li
Structure. Author manuscript; available in PMC 2014 Jul 2.
Published in final edited form as: Structure. 2013 Jul 2; 21(7): 1137–1148. Published online 2013 Jun 6. doi: 10.1016/j.str.2013.04.025
PMCID:
PMC3702631
AbstractArticlePDF–4.3M
5.
Structure of STING bound to c-di-GMP Reveals the Mechanism of Cyclic Dinucleotide Recognition by the Immune System
Chang Shu, Guanghui Yi, Tylan Watts, C. Cheng Kao, Pingwei Li
Nat Struct Mol Biol. Author manuscript; available in PMC 2013 Jan 1.
Published in final edited form as: Nat Struct Mol Biol. 2012 Jul; 19(7): 722–724. Published online 2012 Jun 24. doi: 10.1038/nsmb.2331
PMCID:
PMC3392545
AbstractArticlePDF–667K
6.
Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism
Maroof Hasan, Vijay K. Gonugunta, Nicole Dobbs, Aktar Ali, Guillermo Palchik, Maria A. Calvaruso, Ralph J. DeBerardinis, Nan Yan
Proc Natl Acad Sci U S A. 2017 Jan 24; 114(4): 746–751. Published online 2017 Jan 9. doi: 10.1073/pnas.1611113114
PMCID:
PMC5278463
AbstractArticlePDF–1.3M
7.
Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes
Maroof Hasan, James Koch, Dinesh Rakheja, Asit K. Pattnaik, James Brugarolas, Igor Dozmorov, Beth Levine, Edward K. Wakeland, Min Ae Lee-kirsch, Nan Yan
Nat Immunol. Author manuscript; available in PMC 2013 Jul 1.
Published in final edited form as: Nat Immunol. 2013 Jan; 14(1): 61–71. Published online 2012 Nov 18. doi: 10.1038/ni.2475
PMCID:
PMC3522772
AbstractArticlePDF–1.5M
8.
LPS-induced down-regulation of signal regulatory protein α contributes to innate immune activation in macrophages
Xiao-Ni Kong, He-Xin Yan, Lei Chen, Li-Wei Dong, Wen Yang, Qiong Liu, Le-Xing Yu, Dan-Dan Huang, Shu-Qin Liu, Hui Liu, Meng-Chao Wu, Hong-Yang Wang
J Exp Med. 2007 Oct 29; 204(11): 2719–2731. doi: 10.1084/jem.20062611
PMCID:
PMC2118489
AbstractArticlePDF–4.1M
9.
Involvement of the ubiquitin-like domain of TBK1/IKK-i kinases in regulation of IFN-inducible genes
Fumiyo Ikeda, Christina Maria Hecker, Alexis Rozenknop, Rolf Dietrich Nordmeier, Vladimir Rogov, Kay Hofmann, Shizuo Akira, Volker Dötsch, Ivan Dikic
EMBO J. 2007 Jul 25; 26(14): 3451–3462. Published online 2007 Jun 28. doi: 10.1038/sj.emboj.7601773
PMCID:
PMC1933404
AbstractArticlePDF–379K
10.
The Type I Interferon-IRF7 Axis Mediates Transcriptional Expression of Usp25 Gene
Yujie Ren, Yin Zhao, Dandan Lin, Ximing Xu, Qiyun Zhu, Jing Yao, Hong-Bing Shu, Bo Zhong
J Biol Chem. 2016 Jun 17; 291(25): 13206–13215. Published online 2016 Apr 27. doi: 10.1074/jbc.M116.718080
PMCID:
PMC4933234
AbstractArticlePDF–3.7M
11.
Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth
Philipp Wild, Hesso Farhan, David G. McEwan, Sebastian Wagner, Vladimir V. Rogov, Nathan R. Brady, Benjamin Richter, Jelena Korac, Oliver Waidmann, Chunaram Choudhary, Volker Dötsch, Dirk Bumann, Ivan Dikic
Science. Author manuscript; available in PMC 2013 Jul 18.
Published in final edited form as: Science. 2011 Jul 8; 333(6039): 228–233. Published online 2011 May 26. doi: 10.1126/science.1205405
PMCID:
PMC3714538
AbstractArticlePDF–2.5M
12.
Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin‐2 to induce motor neuron dysfunction and cell death
Chantal Sellier, Maria‐Letizia Campanari, Camille Julie Corbier, Angeline Gaucherot, Isabelle Kolb‐Cheynel, Mustapha Oulad‐Abdelghani, Frank Ruffenach, Adeline Page, Sorana Ciura, Edor Kabashi, Nicolas Charlet‐Berguerand
EMBO J. 2016 Jun 15; 35(12): 1276–1297. Published online 2016 Apr 21. doi: 10.15252/embj.201593350
PMCID:
PMC4910533
AbstractArticlePDF–1.5M
13.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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