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Select item 98151101.

CARMA3: A potential therapeutic target in non-cancer diseases

Zhen Gui, Yan Zhang, Aihua Zhang, Weiwei Xia, Zhanjun Jia

Front Immunol. 2022; 13: 1057980. Published online 2022 Dec 22. doi: 10.3389/fimmu.2022.1057980

PMCID:: PMC9815110

Abstract Article PDF–3.3M

Select item 73316432.

Mutant CARD10 in a family with progressive immunodeficiency and autoimmunity

Dan-hui Yang, Ting Guo, Zhuang-zhuang Yuan, Cheng Lei, Shui-zi Ding, Yi-feng Yang, Zhi-ping Tan, Hong Luo

Cell Mol Immunol. 2020 Jul; 17(7): 782–784. Published online 2020 Apr 1. doi: 10.1038/s41423-020-0423-x

PMCID:: PMC7331643

Article PDF–955K

Select item 68963723.

CARD10 promotes the progression of renal cell carcinoma by regulating the NF-κB signaling pathway

Longfei Peng, Ke He, Zhangjun Cao, Liangkuan Bi, Dexin Yu, Qi Wang, Jinyou Wang

Mol Med Rep. 2020 Jan; 21(1): 329–337. Published online 2019 Nov 21. doi: 10.3892/mmr.2019.10840

PMCID:: PMC6896372

Abstract Article PDF–1.8M

Select item 67679884.

CARMA3/NF-κB signaling contributes to tumorigenesis of hepatocellular carcinoma and is inhibited by sodium aescinate

Hui Hou, Wei-Xiang Li, Xiao Cui, Da-Chen Zhou, Bin Zhang, Xiao-Ping Geng

World J Gastroenterol. 2019 Sep 28; 25(36): 5483–5493. Published online 2019 Sep 28. doi: 10.3748/wjg.v25.i36.5483

PMCID:: PMC6767988

Abstract Article PDF–16M

Select item 46770395.

Lack of association between the CARD10 rs6000782 polymorphism and type 1 autoimmune hepatitis in a Japanese population

Kiyoshi Migita, Yuka Jiuchi, Hiroshi Furukawa, Minoru Nakamura, Atsumasa Komori, Michio Yasunami, Hideko Kozuru, Seigo Abiru, Kazumi Yamasaki, Shinya Nagaoka, Satoru Hashimoto, Shigemune Bekki, Kaname Yoshizawa, Masaaki Shimada, Hiroshi Kouno, Hiroshi Kamitsukasa, Tatsuji Komatsu, Taizo Hijioka, Makoto Nakamuta, Atsushi Naganuma, Haruhiro Yamashita, Hideo Nishimura, Hajime Ohta, Yoko Nakamura, Keisuke Ario, Yukio Oohara, Kazuhiro Sugi, Minoru Tomizawa, Takeaki Sato, Hironao Takahashi, Toyokichi Muro, Fujio Makita, Eiji Mita, Hironori Sakai, Hiroshi Yatsuhashi

BMC Res Notes. 2015; 8: 777. Published online 2015 Dec 12. doi: 10.1186/s13104-015-1733-4

PMCID:: PMC4677039

Abstract Article PDF–941K

Select item 33528486.

Overexpression of CARMA3 in Non-Small-Cell Lung Cancer Is Linked for Tumor Progression

Zixuan Li, Lianyue Qu, Qianze Dong, Bo Huang, Haiying Li, Zhongping Tang, Ying Xu, Wenting Luo, Lifeng Liu, Xueshan Qiu, Enhua Wang

PLoS One. 2012; 7(5): e36903. Published online 2012 May 15. doi: 10.1371/journal.pone.0036903

PMCID:: PMC3352848

Abstract Article PDF–2.2M

Select item 82562547.

CARMA3 Transcriptional Regulation of STMN1 by NF-κB Promotes Renal Cell Carcinoma Proliferation and Invasion

Du Shi, Zhe Zhang, Chuize Kong

Technol Cancer Res Treat. 2021; 20: 15330338211027915. Published online 2021 Jun 30. doi: 10.1177/15330338211027915

PMCID:: PMC8256254

Abstract Article PDF–1.9M

Select item 68509328.

Caspase recruitment domain family member 10 regulates carbamoyl phosphate synthase 1 and promotes cancer growth in bladder cancer cells

Xi Liu, Xiaotong Zhang, Jianbin Bi, Zhenhua Li, Zhe Zhang, Chuize Kong

J Cell Mol Med. 2019 Dec; 23(12): 8128–8138. Published online 2019 Sep 29. doi: 10.1111/jcmm.14683

PMCID:: PMC6850932

Abstract Article PDF–2.0M

Select item 45136719.

Protein kinase Cα-CARMA3 signaling axis links Ras to NF-κB for lysophosphatidic acid-induced urokinase plasminogen activator expression in ovarian cancer cells

C Mahanivong, HM Chen, SW Yee, ZK Pan, Z Dong, S Huang

Oncogene. Author manuscript; available in PMC 2015 Jul 24.

Published in final edited form as: Oncogene. 2008 Feb 21; 27(9): 1273–1280. Published online 2007 Aug 27. doi: 10.1038/sj.onc.1210746

PMCID:: PMC4513671

Abstract Article PDF–1.8M

Select item 377729410.

Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment

K Nho, JJ Corneveaux, S Kim, H Lin, SL Risacher, L Shen, S Swaminathan, VK Ramanan, Y Liu, T Foroud, MH Inlow, AL Siniard, RA Reiman, PS Aisen, RC Petersen, RC Green, CR Jack, MW Weiner, CT Baldwin, K Lunetta, LA Farrer, SJ Furney, S Lovestone, A Simmons, P Mecocci, B Vellas, M Tsolaki, I Kloszewska, H Soininen, BC McDonald, MR Farlow, B Ghetti, MJ Huentelman, AJ Saykin

Mol Psychiatry. Author manuscript; available in PMC 2014 Jul 1.

Published in final edited form as: Mol Psychiatry. 2013 Jul; 18(7): 781–787. Published online 2013 Apr 23. doi: 10.1038/mp.2013.24

PMCID:: PMC3777294

Abstract Article PDF–1.2M

Select item 643609411.

The CARMA3-Bcl10-MALT1 Signalosome Drives NF-κB Activation and Promotes Aggressiveness in Angiotensin II Receptor-positive Breast Cancer.

Prasanna Ekambaram, Jia-Ying (Lloyd) Lee, Nathaniel E. Hubel, Dong Hu, Saigopalakrishna Yerneni, Phil G. Campbell, Netanya Pollock, Linda R. Klei, Vincent J. Concel, Phillip C. Delekta, Arul M. Chinnaiyan, Scott A. Tomlins, Daniel R. Rhodes, Nolan Priedigkeit, Adrian V. Lee, Steffi Oesterreich, Linda M. McAllister-Lucas, Peter C. Lucas

Cancer Res. Author manuscript; available in PMC 2019 Mar 27.

Published in final edited form as: Cancer Res. 2018 Mar 1; 78(5): 1225–1240. Published online 2017 Dec 19. doi: 10.1158/0008-5472.CAN-17-1089

PMCID:: PMC6436094

Abstract Article PDF–2.4M

Select item 567659012.

The CARMA3-BCL10-MALT1 (CBM) complex contributes to DNA damage-induced NF-κB activation and cell survival

Shilei Zhang, Deng Pan, Xin-Ming Jia, Xin Lin, Xueqiang Zhao

Protein Cell. 2017 Nov; 8(11): 856–860. Published online 2017 Jul 17. doi: 10.1007/s13238-017-0441-3

PMCID:: PMC5676590

Article PDF–2.1M

Select item 305984613.

CARMA3 is crucial for EGFR-induced activation of NF-κB and tumor progression

Tang Jiang, Brian Grabiner, Yifan Zhu, Changying Jiang, Hongxiu Li, Yun You, Jingyu Lang, Mien-Chie Hung, Xin Lin

Cancer Res. Author manuscript; available in PMC 2012 Mar 15.

Published in final edited form as: Cancer Res. 2011 Mar 15; 71(6): 2183–2192. doi: 10.1158/0008-5472.CAN-10-3626

PMCID:: PMC3059846

Abstract Article PDF–1.1M

Select item 606803214.

CARD10, a CEBPE target involved in granulocytic differentiation

Pavithra Shyamsunder, Haresh Sankar, Anand Mayakonda, Lin Han, Hazimah Binte Mohd Nordin, Teoh Weoi Woon, Mahalakshmi Shanmugasundaram, Pushkar Dakle, Vikas Madan, H. Phillip Koeffler

Haematologica. 2018 Aug; 103(8): 1269–1277. Prepublished online 2018 May 17. doi: 10.3324/haematol.2018.190280

PMCID:: PMC6068032

Abstract Article PDF–1.9M

Select item 427742515.

The Dishevelled, EGL-10 and Pleckstrin (DEP) Domain-Containing Protein DEPDC7 Binds to CARMA2 and CARMA3 Proteins, and Regulates NF-κB Activation

Egildo Luca D′ Andrea, Angela Ferravante, Ivan Scudiero, Tiziana Zotti, Carla Reale, Maddalena Pizzulo, Luigi Regenburgh De La Motte, Chiara De Maio, Pellegrino Mazzone, Gianluca Telesio, Pasquale Vito, Romania Stilo

PLoS One. 2014; 9(12): e116062. Published online 2014 Dec 26. doi: 10.1371/journal.pone.0116062

PMCID:: PMC4277425

Abstract Article PDF–1.3M

Select item 351550516.

microRNA-146a inhibits G protein-coupled receptor-mediated activation of NF-κB by targeting CARD10 and COPS8 in gastric cancer

Stephanie Geisler Crone, Anders Jacobsen, Birgitte Federspiel, Linda Bardram, Anders Krogh, Anders H Lund, Lennart Friis-Hansen

Mol Cancer. 2012; 11: 71. Published online 2012 Sep 20. doi: 10.1186/1476-4598-11-71

PMCID:: PMC3515505

Abstract Article PDF–3.3M

Select item 347558517.

CXCL12/SDF-1α Activates NF-κB and Promotes Oral Cancer Invasion through the Carma3/Bcl10/Malt1 Complex

Aasia O Rehman, Cun-yu Wang

Int J Oral Sci. 2009 Sep; 1(3): 105–118. doi: 10.4248/IJOS.09059

PMCID:: PMC3475585

Summary PDF–846K

Select item 264552618.

CARMA3 Mediates Lysophosphatidic Acid–Stimulated Cytokine Secretion by Bronchial Epithelial Cells

Benjamin D. Medoff, Aimee L. Landry, Kelley A. Wittbold, Barry P. Sandall, Merran C. Derby, Zhifang Cao, Joe C. Adams, Ramnik J. Xavier

Am J Respir Cell Mol Biol. 2009 Mar; 40(3): 286–294. Published online 2008 Aug 28. doi: 10.1165/rcmb.2008-0129OC

PMCID:: PMC2645526

Abstract Article PDF–713K

Select item 176631719.

CARMA3/Bcl10/MALT1-dependent NF-κB activation mediates angiotensin II-responsive inflammatory signaling in nonimmune cells

Linda M. McAllister-Lucas, Jürgen Ruland, Katy Siu, Xiaohong Jin, Shufang Gu, David S. L. Kim, Peter Kuffa, Dawn Kohrt, Tak W. Mak, Gabriel Nuñez, Peter C. Lucas

Proc Natl Acad Sci U S A. 2007 Jan 2; 104(1): 139–144. Published online 2006 Nov 13. doi: 10.1073/pnas.0601947103

PMCID:: PMC1766317

Abstract Article PDF–1.0M

Select item 264910320.

CXCL8/IL8 Stimulates Vascular Endothelial Growth Factor (VEGF) Expression and the Autocrine Activation of VEGFR2 in Endothelial Cells by Activating NFκB through the CBM (Carma3/Bcl10/Malt1) Complex

Daniel Martin, Rebeca Galisteo, J. Silvio Gutkind

J Biol Chem. 2009 Mar 6; 284(10): 6038–6042. doi: 10.1074/jbc.C800207200

PMCID:: PMC2649103

Abstract Article PDF–650K

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