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Select item 90986941.

Role of adenosine kinase in sphingosine-1-phosphate receptor 1-induced mechano-hypersensitivities

Filomena Lauro, Luigino Antonio Giancotti, Grant Kolar, Caron Mitsue Harada, Taylor A. Harmon, Timothy J Garrett, Daniela Salvemini

Cell Mol Neurobiol. Author manuscript; available in PMC 2023 Nov 1.

Published in final edited form as: Cell Mol Neurobiol. 2022 Nov; 42(8): 2909–2918. Published online 2021 Nov 13. doi: 10.1007/s10571-021-01162-8

PMCID:: PMC9098694

Abstract Article PDF–1015K

Select item 86057662.

In Vitro and In Vivo Investigation of S1PR1 Expression in the Central Nervous System Using [³H]CS1P1 and [¹¹C]CS1P1

Hao Jiang, Sumit Joshi, Hui Liu, Syahir Mansor, Lin Qiu, Haiyang Zhao, Timothy Whitehead, Robert J. Gropler, Gregory F. Wu, Anne H. Cross, Tammie L. S. Benzinger, Kooresh I. Shoghi, Joel S. Perlmutter, Zhude Tu

ACS Chem Neurosci. Author manuscript; available in PMC 2022 Oct 6.

Published in final edited form as: ACS Chem Neurosci. 2021 Oct 6; 12(19): 3733–3744. Published online 2021 Sep 13. doi: 10.1021/acschemneuro.1c00492

PMCID:: PMC8605766

Abstract Article PDF–2.5M

Select item 51534663.

Activation of Sphingosine 1-Phosphate Receptor 1 Enhances Hippocampus Neurogenesis in a Rat Model of Traumatic Brain Injury: An Involvement of MEK/Erk Signaling Pathway

Yuqin Ye, Zhenyu Zhao, Hongyu Xu, Xin Zhang, Xinhong Su, Yongxiang Yang, Xinguang Yu, Xiaosheng He

Neural Plast. 2016; 2016: 8072156. Published online 2016 Nov 29. doi: 10.1155/2016/8072156

PMCID:: PMC5153466

Abstract Article PDF–3.3M

Select item 41103124.

The Development and Maintenance of Paclitaxel-induced Neuropathic Pain Require Activation of the Sphingosine 1-Phosphate Receptor Subtype 1

Kali Janes, Joshua W. Little, Chao Li, Leesa Bryant, Collin Chen, Zhoumou Chen, Krzysztof Kamocki, Timothy Doyle, Ashley Snider, Emanuela Esposito, Salvatore Cuzzocrea, Erhard Bieberich, Lina Obeid, Irina Petrache, Grant Nicol, William L. Neumann, Daniela Salvemini

J Biol Chem. 2014 Jul 25; 289(30): 21082–21097. Published online 2014 May 29. doi: 10.1074/jbc.M114.569574

PMCID:: PMC4110312

Abstract Article PDF–3.9M

Select item 34724565.

Expression of sphingosine 1-phosphate receptors in the rat dorsal root ganglia and defined single isolated sensory neurons

J. S. Kays, Chao Li, G. D. Nicol

Physiol Genomics. 2012 Sep 15; 44(18): 889–901. Published online 2012 Jul 17. doi: 10.1152/physiolgenomics.00053.2012

PMCID:: PMC3472456

Abstract Article

Select item 33222676.

Knockdown of the sphingosine-1-phosphate receptor S1PR1 reduces pain behaviors induced by local inflammation of the rat sensory ganglion

Wenrui Xie, Judith A. Strong, Joanne Kays, Grant D. Nicol, Jun-Ming Zhang

Neurosci Lett. Author manuscript; available in PMC 2013 Apr 25.

Published in final edited form as: Neurosci Lett. 2012 Apr 25; 515(1): 61–65. Published online 2012 Mar 16. doi: 10.1016/j.neulet.2012.03.019

PMCID:: PMC3322267

Abstract Article PDF–849K

Select item 31197827.

Sphingosine-1-phosphate Acting via the S1P₁ Receptor is a Downstream Signaling Pathway in Ceramide-Induced Hyperalgesia

Tim Doyle, Zhoumou Chen, Lina M. Obeid, Daniela Salvemini

Neurosci Lett. Author manuscript; available in PMC 2012 Jul 15.

Published in final edited form as: Neurosci Lett. 2011 Jul 15; 499(1): 4–8. Published online 2011 May 13. doi: 10.1016/j.neulet.2011.05.018

PMCID:: PMC3119782

Abstract Article PDF–468K

Select item 29970358.

The Sphingosine 1-Phosphate Receptor, S1PR₁, Plays a Prominent But Not Exclusive Role in Enhancing the Excitability of Sensory Neurons

Xian Xuan Chi, G. D. Nicol

J Neurophysiol. 2010 Nov; 104(5): 2741–2748. Published online 2010 Sep 15. doi: 10.1152/jn.00709.2010

PMCID:: PMC2997035

Abstract Article

Select item 29932149.

Sphingosine-1-phosphate prevents permeability increases via activation of endothelial sphingosine-1-phosphate receptor 1 in rat venules

Gengqian Zhang, Sulei Xu, Yan Qian, Pingnian He

Am J Physiol Heart Circ Physiol. 2010 Nov; 299(5): H1494–H1504. Published online 2010 Aug 20. doi: 10.1152/ajpheart.00462.2010

PMCID:: PMC2993214

Abstract Article

Select item 282542510.

Down-regulation of S1P₁ Receptor Surface Expression by Protein Kinase C Inhibition

Sven-Christian Sensken, Markus H. Gräler

J Biol Chem. 2010 Feb 26; 285(9): 6298–6307. Published online 2009 Dec 23. doi: 10.1074/jbc.M109.049692

PMCID:: PMC2825425

Abstract Article PDF–2.2M

Select item 275414811.

SPHINGOSINE-1-PHOSPHATE RECEPTORS MEDIATE NEUROMODULATORY FUNCTIONS IN THE CNS

Laura J. Sim-Selley, Paulette B. Goforth, Mba U. Mba, Timothy L. Macdonald, Kevin R. Lynch, Sheldon Milstien, Sarah Spiegel, Leslie S. Satin, Sandra P. Welch, Dana E. Selley

J Neurochem. Author manuscript; available in PMC 2010 Aug 1.

Published in final edited form as: J Neurochem. 2009 Aug; 110(4): 1191–1202. Published online 2009 May 31. doi: 10.1111/j.1471-4159.2009.06202.x

PMCID:: PMC2754148

Abstract Article PDF–1.1M

Select item 10218212.

Inhibitory Regulation of Rac Activation, Membrane Ruffling, and Cell Migration by the G Protein-Coupled Sphingosine-1-Phosphate Receptor EDG5 but Not EDG1 or EDG3

Hiroyuki Okamoto, Noriko Takuwa, Takehiko Yokomizo, Naotoshi Sugimoto, Soutaro Sakurada, Hiroshi Shigematsu, Yoh Takuwa

Mol Cell Biol. 2000 Dec; 20(24): 9247–9261. doi: 10.1128/mcb.20.24.9247-9261.2000

PMCID:: PMC102182

Abstract Article PDF–2.9M

Select item 1060013513.

The GPCR adaptor protein Norbin regulates S1PR1 trafficking and the morphology, cell cycle and survival of PC12 cells

Valdemar B. I. Johansen, Elizabeth Hampson, Elpida Tsonou, Chiara Pantarelli, Julia Y. Chu, Laraine Crossland, Hanneke Okkenhaug, Andrew J. Massey, David C. Hornigold, Heidi C. E. Welch, Stephen A. Chetwynd

Sci Rep. 2023; 13: 18237. Published online 2023 Oct 25. doi: 10.1038/s41598-023-45148-6

PMCID:: PMC10600135

Abstract Article PDF–4.2M

Select item 835431314.

Interference with the expression of S1PR1 or STAT3 attenuates valvular damage due to rheumatic heart disease

Shenglin Xian, Ang Chen, Yunjiao Wu, Hong Wen, Chuanghong Lu, Feng Huang, Zhiyu Zeng

Int J Mol Med. 2021 Sep; 48(3): 179. Published online 2021 Jul 21. doi: 10.3892/ijmm.2021.5012

PMCID:: PMC8354313

Abstract Article PDF–1.4M

Select item 542658815.

The effect of sphingosine-1-phosphate on colonic smooth muscle contractility: Modulation by TNBS-induced colitis

Aishah Al-Jarallah, Mabayoje Oriowo

PLoS One. 2017; 12(5): e0170792. Published online 2017 May 11. doi: 10.1371/journal.pone.0170792

PMCID:: PMC5426588

Abstract Article PDF–5.7M

Select item 333833616.

Crystal Structure of a Lipid G protein-Coupled Receptor

Michael A. Hanson, Christopher B. Roth, Euijung Jo, Mark T. Griffith, Fiona L. Scott, Greg Reinhart, Hans Desale, Bryan Clemons, Stuart M. Cahalan, Stephan C. Schuerer, M. Germana Sanna, Gye Won Han, Peter Kuhn, Hugh Rosen, Raymond C. Stevens

Science. Author manuscript; available in PMC 2013 Feb 17.

Published in final edited form as: Science. 2012 Feb 17; 335(6070): 851–855. doi: 10.1126/science.1215904

PMCID:: PMC3338336

Abstract Article PDF–4.0M

Select item 316241117.

FTY720 (Gilenya) Phosphate Selectivity of Sphingosine 1-Phosphate Receptor Subtype 1 (S1P₁) G Protein-coupled Receptor Requires Motifs in Intracellular Loop 1 and Transmembrane Domain 2

William J. Valentine, Virginia I. Godwin, Daniel A. Osborne, Jianxiong Liu, Yuko Fujiwara, James Van Brocklyn, Robert Bittman, Abby L. Parrill, Gabor Tigyi

J Biol Chem. 2011 Sep 2; 286(35): 30513–30525. Published online 2011 Jun 30. doi: 10.1074/jbc.M111.263442