PMC Links for Gene (Select 29702) - PMC

Baldwin C. Mak, Qin Wang, Carol Laschinger, Wilson Lee, David Ron, Heather P. Harding, Randal J. Kaufman, Donalyn Scheuner, Richard C. Austin, Christopher A. McCulloch

J Biol Chem. 2008 Aug 22; 283(34): 23462–23472. doi: 10.1074/jbc.M803194200

PMCID:: PMC2517009

Abstract Article PDF–814K

Select item 1338335.

The PERK Eukaryotic Initiation Factor 2α Kinase Is Required for the Development of the Skeletal System, Postnatal Growth, and the Function and Viability of the Pancreas

Peichuan Zhang, Barbara McGrath, Sheng'ai Li, Ami Frank, Frank Zambito, Jamie Reinert, Maureen Gannon, Kun Ma, Kelly McNaughton, Douglas R. Cavener

Mol Cell Biol. 2002 Jun; 22(11): 3864–3874. doi: 10.1128/MCB.22.11.3864-3874.2002

PMCID:: PMC133833

Abstract Article PDF–1.1M

Select item 93814926.

HIIT and MICT attenuate high-fat diet-induced hepatic lipid accumulation and ER stress via the PERK-ATF4-CHOP signaling pathway

Zhang Yuan, Liu Xiao-wei, Wei Juan, Liu Xiu-juan, Zhang Nian-yun, Sheng Lei

J Physiol Biochem. 2022; 78(3): 641–652. Published online 2022 Mar 22. doi: 10.1007/s13105-022-00884-7

PMCID:: PMC9381492

Abstract Article PDF–4.9M

Select item 41769987.

Protein kinase RNA- like endoplasmic reticulum kinase (PERK) signaling pathway plays a major role in reactive oxygen species (ROS)- mediated endoplasmic reticulum stress- induced apoptosis in diabetic cardiomyopathy

Zhong-Wei Liu, Hai-Tao Zhu, Kun-Lun Chen, Xin Dong, Jin Wei, Chuan Qiu, Jia-Hong Xue

Cardiovasc Diabetol. 2013; 12: 158. Published online 2013 Nov 2. doi: 10.1186/1475-2840-12-158

PMCID:: PMC4176998

Abstract Article PDF–1.7M

Select item 38371258.

Insulin Secretion and Ca²⁺ Dynamics in β-Cells Are Regulated by PERK (EIF2AK3) in Concert with Calcineurin

Rong Wang, Barbara C. McGrath, Richard F. Kopp, Michael W. Roe, Xin Tang, Gong Chen, Douglas R. Cavener

J Biol Chem. 2013 Nov 22; 288(47): 33824–33836. Published online 2013 Oct 10. doi: 10.1074/jbc.M113.503664

PMCID:: PMC3837125

Abstract Article PDF–2.1M

Select item 30702119.

PERK Activation at Low Glucose Concentration Is Mediated by SERCA Pump Inhibition and Confers Preemptive Cytoprotection to Pancreatic β-Cells

Claire E. Moore, Omotola Omikorede, Edith Gomez, Gary B. Willars, Terence P. Herbert

Mol Endocrinol. 2011 Feb; 25(2): 315–326. Published online 2010 Dec 30. doi: 10.1210/me.2010-0309

PMCID:: PMC3070211

Abstract Article

Select item 312206210.

Induction of ER stress in response to oxygen-glucose deprivation of cortical cultures involves the activation of the PERK and IRE-1 pathways and of caspase-12

N Badiola, C Penas, A Miñano-Molina, B Barneda-Zahonero, R Fadó, G Sánchez-Opazo, J X Comella, J Sabriá, C Zhu, K Blomgren, C Casas, J Rodríguez-Alvarez

Cell Death Dis. 2011 Apr; 2(4): e149. Published online 2011 Apr 28. doi: 10.1038/cddis.2011.31

PMCID:: PMC3122062

Abstract Article PDF–531K

Select item 257099511.

PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation

Ekaterina Bobrovnikova-Marjon, Georgia Hatzivassiliou, Christina Grigoriadou, Margarita Romero, Douglas R. Cavener, Craig B. Thompson, J. Alan Diehl

Proc Natl Acad Sci U S A. 2008 Oct 21; 105(42): 16314–16319. Published online 2008 Oct 13. doi: 10.1073/pnas.0808517105

PMCID:: PMC2570995

Abstract Article PDF–1.1M

Select item 217169612.

Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-γ

Wensheng Lin, Heather P. Harding, David Ron, Brian Popko

J Cell Biol. 2005 May 23; 169(4): 603–612. doi: 10.1083/jcb.200502086

PMCID:: PMC2171696

Abstract Article PDF–2.0M

Select item 122085213.

Pancreatic eukaryotic initiation factor-2alpha kinase (PEK) homologues in humans, Drosophila melanogaster and Caenorhabditis elegans that mediate translational control in response to endoplasmic reticulum stress.

R Sood, A C Porter, K Ma, L A Quilliam, R C Wek

Biochem J. 2000 Mar 1; 346(Pt 2): 281–293.

PMCID:: PMC1220852

Summary PDF–449K

Select item 374342514.

The Unfolded Protein Response Induces the Angiogenic Switch in Human Tumor Cells through the PERK/ATF4 Pathway

Yugang Wang, Goleeta N. Alam, Yu Ning, Fernanda Visioli, Zhihong Dong, Jacques E. Nör, Peter J. Polverini

Cancer Res. Author manuscript; available in PMC 2013 Oct 15.

Published in final edited form as: Cancer Res. 2012 Oct 15; 72(20): 5396–5406. Published online 2012 Aug 20. doi: 10.1158/0008-5472.CAN-12-0474

PMCID:: PMC3743425

Abstract Article PDF–6.1M

Select item 156619015.

The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response

Jiahai Zhou, Chuan Yin Liu, Sung Hoon Back, Robert L. Clark, Daniel Peisach, Zhaohui Xu, Randal J. Kaufman

Proc Natl Acad Sci U S A. 2006 Sep 26; 103(39): 14343–14348. Published online 2006 Sep 14. doi: 10.1073/pnas.0606480103

PMCID:: PMC1566190

Abstract Article PDF–1.9M

Select item 52496916.

Resistance to Vesicular Stomatitis Virus Infection Requires a Functional Cross Talk between the Eukaryotic Translation Initiation Factor 2α Kinases PERK and PKR

Dionissios Baltzis, Li-Ke Qu, Stavroula Papadopoulou, Jaime D. Blais, John C. Bell, Nahum Sonenberg, Antonis E. Koromilas

J Virol. 2004 Dec; 78(23): 12747–12761. doi: 10.1128/JVI.78.23.12747-12761.2004

PMCID:: PMC524969

Abstract Article PDF–1.0M

Select item 14950917.

Protein Synthesis and Endoplasmic Reticulum Stress Can Be Modulated by the Hepatitis C Virus Envelope Protein E2 through the Eukaryotic Initiation Factor 2α Kinase PERK

Nicole Pavio, Patrick R. Romano, Thomas M. Graczyk, Stephen M. Feinstone, Deborah R. Taylor

J Virol. 2003 Mar; 77(6): 3578–3585. doi: 10.1128/JVI.77.6.3578-3585.2003

PMCID:: PMC149509

Abstract Article PDF–580K

Select item 598621818.

Sirtuin-1 (SIRT1) stimulates growth-plate chondrogenesis by attenuating the PERK–eIF-2α–CHOP pathway in the unfolded protein response

Xiaomin Kang, Wei Yang, Ruiqi Wang, Tianping Xie, Huixia Li, Dongxu Feng, Xinxin Jin, Hongzhi Sun, Shufang Wu

J Biol Chem. 2018 Jun 1; 293(22): 8614–8625. Published online 2018 Apr 13. doi: 10.1074/jbc.M117.809822

PMCID:: PMC5986218

Abstract Article PDF–3.2M

Select item 349428419.

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK and IRE1a-mediated unfolded protein response

Miri Jwa, Paul Chang

Nat Cell Biol. Author manuscript; available in PMC 2013 May 1.

Published in final edited form as: Nat Cell Biol. 2012 Nov; 14(11): 1223–1230. Published online 2012 Oct 28. doi: 10.1038/ncb2593

Correction in:: volume 15 on page 123

PMCID:: PMC3494284

Abstract Article PDF–1.6M

Select item 332841120.

H₂S-induced sulfhydration of PTP1B and its role in the endoplasmic reticulum stress response

Navasona Krishnan, Cexiong Fu, Darryl Pappin, Nicholas K. Tonks

Sci Signal. Author manuscript; available in PMC 2012 Apr 17.

Published in final edited form as: Sci Signal. 2011 Dec 13; 4(203): ra86. Published online 2011 Dec 13. doi: 10.1126/scisignal.2002329

PMCID:: PMC3328411

Abstract Article PDF–1.1M

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