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Select item 91221941.

P2X4 receptors mediate induction of antioxidants, fibrogenic cytokines and ECM transcripts; in presence of replicating HCV in in vitro setting: An insight into role of P2X4 in fibrosis

Sobia Manzoor, Madiha Khalid, Muhammad Idrees

PLoS One. 2022; 17(5): e0259727. Published online 2022 May 20. doi: 10.1371/journal.pone.0259727

PMCID:: PMC9122194

Abstract Article PDF–2.0M

Select item 84109162.

Enhanced expression of P2X4 purinoceptors in pyramidal neurons of the rat hippocampal CA1 region may be involved ischemia-reperfusion injury

Zhenghua Xiang, Xin Jiang, Rihui Ji, Hongbin Yuan

Purinergic Signal. 2021 Sep; 17(3): 425–438. Published online 2021 May 9. doi: 10.1007/s11302-021-09780-z

PMCID:: PMC8410916

Abstract Article PDF–13M

Select item 78212273.

Electroacupuncture effects on the P2X4R pathway in microglia regulating the excitability of neurons in the substantia gelatinosa region of rats with spinal nerve ligation

Yuyin Zheng, Chengqian Jia, Xia Jiang, Jie Chen, Xiao-Long Chen, Xinwang Ying, Jiayu Wu, Mingchen Jiang, Guanhu Yang, Wenzhan Tu, Kecheng Zhou, Songhe Jiang

Mol Med Rep. 2021 Mar; 23(3): 175. Published online 2020 Dec 30. doi: 10.3892/mmr.2020.11814

PMCID:: PMC7821227

Abstract Article PDF–769K

Select item 73406854.

Overexpression of Purinergic P2X4 Receptors in Hippocampus Rescues Memory Impairment in Rats with Type 2 Diabetes

Ping-An Zhang, Qian Sun, Yong-Chang Li, Rui-Xia Weng, Rui Wu, Hong-Hong Zhang, Guang-Yin Xu

Neurosci Bull. 2020 Jul; 36(7): 719–732. Published online 2020 Mar 20. doi: 10.1007/s12264-020-00478-7

PMCID:: PMC7340685

Abstract Article PDF–4.5M

Select item 67577585.

P2X Receptor Trafficking in Neurons Is Subunit Specific

Laura K. Bobanovic, Stephen J. Royle, Ruth D. Murrell-Lagnado

J Neurosci. 2002 Jun 15; 22(12): 4814–4824. doi: 10.1523/JNEUROSCI.22-12-04814.2002

PMCID:: PMC6757758

Abstract Article PDF–836K

Select item 65786476.

A novel neuronal P2x ATP receptor ion channel with widespread distribution in the brain

P Seguela, A Haghighi, JJ Soghomonian, E Cooper

J Neurosci. 1996 Jan 15; 16(2): 448–455. doi: 10.1523/JNEUROSCI.16-02-00448.1996

PMCID:: PMC6578647

Abstract PDF–1.1M

Select item 41076537.

Conserved extracellular cysteines differentially regulate the potentiation produced by Zn²⁺ in rat P2X4 receptors

Chao-Ying Li, Ke-Ming Xiong, Yu-Xiang Wu, Yu-Wei Liu, Lin Chen, Randall R. Stewart, Robert W. Peoples, Chu-Li Yi

Eur J Pharmacol. Author manuscript; available in PMC 2014 Jul 23.

Published in final edited form as: Eur J Pharmacol. 2013 May 5; 707(0): 11–16. Published online 2013 Mar 22. doi: 10.1016/j.ejphar.2013.03.011

PMCID:: PMC4107653

Abstract Article PDF–240K

Select item 40119478.

Sensitization of Cutaneous, Neuronal Purinergic Receptors Contributes to Endothelin-1-Induced Mechanical Hypersensitivity

Travis P. Barr, Alen Hrnjic, Alla Khodorova, Jared M. Sprague, Gary R. Strichartz

Pain. Author manuscript; available in PMC 2015 Jun 1.

Published in final edited form as: Pain. 2014 Jun; 155(6): 1091–1101. Published online 2014 Feb 22. doi: 10.1016/j.pain.2014.02.014

PMCID:: PMC4011947

Abstract Article PDF–1.1M

Select item 36054399.

Multiple Roles of the Extracellular Vestibule Amino Acid Residues in the Function of the Rat P2X4 Receptor

Milos B. Rokic, Stanko S. Stojilkovic, Vojtech Vavra, Pavlo Kuzyk, Vendula Tvrdonova, Hana Zemkova

PLoS One. 2013; 8(3): e59411. Published online 2013 Mar 21. doi: 10.1371/journal.pone.0059411

PMCID:: PMC3605439

Abstract Article PDF–1.1M

Select item 323929310.

Hypoxia induced amoeboid microglial cell activation in postnatal rat brain is mediated by ATP receptor P2X4

Fan Li, Lei Wang, Ji-Wei Li, Min Gong, Liang He, Rui Feng, Zhen Dai, Shu-Qing Li

BMC Neurosci. 2011; 12: 111. Published online 2011 Nov 4. doi: 10.1186/1471-2202-12-111

PMCID:: PMC3239293

Abstract Article PDF–6.2M

Select item 317052411.

Roles of Conserved Ectodomain Cysteines of the Rat P2X4 Purinoreceptor in Agonist Binding and Channel Gating

Milos Rokic, Vendula Tvrdonova, Vojtech Vavra, Marie Jindrichova, Tomas Obsil, Stanko S. Stojilkovic, Hana Zemkova

Physiol Res. Author manuscript; available in PMC 2011 Sep 10.

Published in final edited form as: Physiol Res. 2010; 59(6): 927–935. Published online 2010 Apr 20. doi: 10.33549/physiolres.931979

PMCID:: PMC3170524

Abstract Article PDF–1.3M

Select item 316753712.

Fusion-activated Ca²⁺ entry via vesicular P2X₄ receptors promotes fusion pore opening and exocytotic content release in pneumocytes

Pika Miklavc, Norbert Mair, Oliver H. Wittekindt, Thomas Haller, Paul Dietl, Edward Felder, Melanie Timmler, Manfred Frick

Proc Natl Acad Sci U S A. 2011 Aug 30; 108(35): 14503–14508. Published online 2011 Aug 15. doi: 10.1073/pnas.1101039108

PMCID:: PMC3167537

Abstract Article PDF–578K

Select item 284420413.

P2X4 Activation Modulates Volume-sensitive Outwardly Rectifying Chloride Channels in Rat Hepatoma Cells

Diego Varela, Antonello Penna, Felipe Simon, Ana Luisa Eguiguren, Elías Leiva-Salcedo, Oscar Cerda, Francisco Sala, Andrés Stutzin

J Biol Chem. 2010 Mar 5; 285(10): 7566–7574. Published online 2010 Jan 7. doi: 10.1074/jbc.M109.063693

PMCID:: PMC2844204

Abstract Article PDF–4.6M

Select item 283852214.

Characterization of purinergic P2X₄ receptor channels expressed in anterior pituitary cells

Hana Zemkova, Marek Kucka, Shuo Li, Arturo E. Gonzalez-Iglesias, Melanija Tomic, Stanko S. Stojilkovic

Am J Physiol Endocrinol Metab. 2010 Mar; 298(3): E644–E651. Published online 2009 Dec 15. doi: 10.1152/ajpendo.00558.2009

PMCID:: PMC2838522

Abstract Article

Select item 267590815.

Direct Observation of ATP-Induced Conformational Changes in Single P2X₄ Receptors

Youichi Shinozaki, Koji Sumitomo, Makoto Tsuda, Schuichi Koizumi, Kazuhide Inoue, Keiichi Torimitsu

PLoS Biol. 2009 May; 7(5): e1000103. Published online 2009 May 5. doi: 10.1371/journal.pbio.1000103

PMCID:: PMC2675908

Abstract Article PDF–748K

Select item 221751216.

Secondary Structure and Gating Rearrangements of Transmembrane Segments in Rat P2X₄ Receptor Channels

Shai D. Silberberg, Tsg-Hui Chang, Kenton J. Swartz

J Gen Physiol. 2005 Apr; 125(4): 347–359. doi: 10.1085/jgp.200409221

PMCID:: PMC2217512

Abstract Article PDF–2.1M

Select item 44991717.

An antagonist-insensitive P2X receptor expressed in epithelia and brain.

G Buell, C Lewis, G Collo, R A North, A Surprenant

EMBO J. 1996 Jan 2; 15(1): 55–62.

PMCID:: PMC449917

Summary Page Browse PDF–1.7M

Select item 3967218.

P2X4: an ATP-activated ionotropic receptor cloned from rat brain.

F Soto, M Garcia-Guzman, J M Gomez-Hernandez, M Hollmann, C Karschin, W Stühmer

Proc Natl Acad Sci U S A. 1996 Apr 16; 93(8): 3684–3688. doi: 10.1073/pnas.93.8.3684

PMCID:: PMC39672

Summary Page Browse PDF–1.8M

Select item 998466219.

Dorsal root ganglia P2X4 and P2X7 receptors contribute to diabetes-induced hyperalgesia and the downregulation of electroacupuncture on P2X4 and P2X7

Qun-qi Hu, Xiao-fen He, Yi-qi Ma, Li-qian Ma, Si-ying Qu, Han-zhi Wang, Yu-rong Kang, Lu-hang Chen, Xiang Li, Bo-yu Liu, Xiao-mei Shao, Jun-fan Fang, Yi Liang, Jian-qiao Fang, Yong-liang Jiang

Purinergic Signal. 2023 Mar; 19(1): 29–41. Published online 2022 Feb 26. doi: 10.1007/s11302-022-09844-8

PMCID:: PMC9984662

Abstract Article PDF–2.9M

Select item 667534120.

Altered Hippocampal Synaptic Potentiation in P2X₄ Knock-Out Mice

Joan A. Sim, Séverine Chaumont, Jihoon Jo, Lauriane Ulmann, Mark T. Young, Kwangwook Cho, Gary Buell, R. Alan North, Francois Rassendren

J Neurosci. 2006 Aug 30; 26(35): 9006–9009. doi: 10.1523/JNEUROSCI.2370-06.2006

PMCID:: PMC6675341

Abstract Article PDF–337K

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PMC Links for Gene (Select 29659) (44)
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P2X purinoceptor 4 [Rattus norvegicus]
P2X purinoceptor 4 [Rattus norvegicus]
gi|1937369509|ref|NP_113782.2|

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