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Select item 69432231.

GSTZ1‐1 downregulates Wnt/β‐catenin signalling in hepatocellular carcinoma cells

Chong Lei, Qiujie Wang, Ni Tang, Kai Wang

FEBS Open Bio. 2020 Jan; 10(1): 6–17. Published online 2019 Dec 10. doi: 10.1002/2211-5463.12769

PMCID:: PMC6943223

Article PDF–4.2M

Select item 67836482.

GSTZ1 genotypes correlate with dichloroacetate pharmacokinetics and chronic side effects in multiple myeloma patients in a pilot phase 2 clinical trial

Dan Dan Tian, Samuel K. Bennett, Lucy A. Coupland, Kathryn Forwood, Yadanar Lwin, Niloofar Pooryousef, Illa Tea, Thy T. Truong, Teresa Neeman, Philip Crispin, James D’Rozario, Anneke C. Blackburn

Pharmacol Res Perspect. 2019 Dec; 7(6): e00526. Published online 2019 Oct 8. doi: 10.1002/prp2.526

PMCID:: PMC6783648

Article PDF–2.1M

Select item 60380283.

Guo Zhong, Margaret O. James, Marci G. Smeltz, Stephan C. Jahn, Taimour Langaee, Pippa Simpson, Peter W. Stacpoole

Drug Metab Dispos. 2018 Aug; 46(8): 1118–1128. Published online 2018 Aug. doi: 10.1124/dmd.118.081810

PMCID:: PMC6038028

Article PDF–1.2M

Select item 43824404.

The influence of human GSTZ1 gene haplotype variations on GSTZ1 expression

Taimour Langaee, Guo Zhong, Wenjun Li, Issam Hamadeh, Mohamed Hassan M. Solayman, Caitrin W. McDonough, Peter W. Stacpoole, Margaret O. James

Pharmacogenet Genomics. Author manuscript; available in PMC 2016 May 1.

Published in final edited form as: Pharmacogenet Genomics. 2015 May; 25(5): 239–245. doi: 10.1097/FPC.0000000000000129

PMCID:: PMC4382440

Article PDF–243K

Select item 42764895.

Haplotype Variations in Glutathione Transferase Zeta 1 Influence the Kinetics and Dynamics of Chronic Dichloroacetate in Children

Shroads AL, Coats BS, McDonough CW, Langaee T, Stacpoole PW

J Clin Pharmacol. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: J Clin Pharmacol. 2015 Jan; 55(1): 50–55. Published online 2014 Aug 6. doi: 10.1002/jcph.371

PMCID:: PMC4276489

Article PDF–247K

Select item 32639396.

Prenatal and Postnatal Expression of Glutathione Transferase ζ 1 in Human Liver and the Roles of Haplotype and Subject Age in Determining Activity with Dichloroacetate

Wenjun Li, Yuan Gu, Margaret O. James, Ronald N. Hines, Pippa Simpson, Taimour Langaee, Peter W. Stacpoole

Drug Metab Dispos. 2012 Feb; 40(2): 232–239. doi: 10.1124/dmd.111.041533

PMCID:: PMC3263939

Article PDF–777K

Select item 12190067.

Zeta, a novel class of glutathione transferases in a range of species from plants to humans.

P G Board, R T Baker, G Chelvanayagam, L S Jermiin

Biochem J. 1997 Dec 15; 328(Pt 3): 929–935. doi: 10.1042/bj3280929

PMCID:: PMC1219006

Summary PDF–785K

Select item 648348.

Investigation of glutathione S-transferase zeta and the development of sporadic breast cancer

Robert A Smith, Joanne E Curran, Stephen R Weinstein, Lyn R Griffiths

Breast Cancer Res. 2001; 3(6): 409–411. Published online 2001 Oct 10. doi: 10.1186/bcr332

PMCID:: PMC64834

Article PDF–44K

Select item 80877049.

GSTZ1 sensitizes hepatocellular carcinoma cells to sorafenib-induced ferroptosis via inhibition of NRF2/GPX4 axis

Qiujie Wang, Cheng Bin, Qiang Xue, Qingzhu Gao, Ailong Huang, Kai Wang, Ni Tang

Cell Death Dis. 2021 May; 12(5): 426. Published online 2021 Apr 30. doi: 10.1038/s41419-021-03718-4

PMCID:: PMC8087704

Article PDF–4.9M

Select item 728904910.

Stephan C. Jahn, Lauren A. Gay, Claire J. Weaver, Rolf Renne, Taimour Y. Langaee, Peter W. Stacpoole, Margaret O. James

Drug Metab Dispos. 2020 Jul; 48(7): 563–569. Published online 2020 Jul. doi: 10.1124/dmd.120.090639

PMCID:: PMC7289049

Article PDF–686K

Select item 682248311.

GSTZ1 deficiency promotes hepatocellular carcinoma proliferation via activation of the KEAP1/NRF2 pathway

Jingjing Li, Qiujie Wang, Yi Yang, Chong Lei, Fan Yang, Li Liang, Chang Chen, Jie Xia, Kai Wang, Ni Tang

J Exp Clin Cancer Res. 2019; 38: 438. Published online 2019 Oct 30. doi: 10.1186/s13046-019-1459-6

PMCID:: PMC6822483

Article PDF–7.5M

Select item 666992312.

GSTZ1‐1 Deficiency Activates NRF2/IGF1R Axis in HCC via Accumulation of Oncometabolite Succinylacetone

Fan Yang, Jingjing Li, Haijun Deng, Yihao Wang, Chong Lei, Qiujie Wang, Jin Xiang, Li Liang, Jie Xia, Xuanming Pan, Xiaosong Li, Quanxin Long, Lei Chang, Ping Xu, Ailong Huang, Kai Wang, Ni Tang

EMBO J. 2019 Aug 1; 38(15): e101964. Published online 2019 Jun 28. doi: 10.15252/embj.2019101964

PMCID:: PMC6669923

Article PDF–3.8M

Select item 370509613.

MAP3K7 and GSTZ1 are associated with human longevity: a two-stage case–control study using a multilocus genotyping

Fausta Di Cianni, Daniele Campa, Federica Tallaro, Cosmeri Rizzato, Francesco De Rango, Roberto Barale, Giuseppe Passarino, Federico Canzian, Federica Gemignani, Alberto Montesanto, Stefano Landi, Giuseppina Rose

Age (Dordr) 2013 Aug; 35(4): 1357–1366. Published online 2012 May 11. doi: 10.1007/s11357-012-9416-8

PMCID:: PMC3705096

Article PDF–253K

Select item 121936314.

Glutathione transferase zeta catalyses the oxygenation of the carcinogen dichloroacetic acid to glyoxylic acid.

Z Tong, P G Board, M W Anders

Biochem J. 1998 Apr 15; 331(Pt 2): 371–374. doi: 10.1042/bj3310371

PMCID:: PMC1219363

Summary PDF–231K

Select item 332134915.

Preliminary Examination of Polymorphisms of GSTM1, GSTT1, and GSTZ1 in Relation to Semen Quality

Andrew F. Olshan, Thomas J. Luben, Nancy M. Hanley, Sally D. Perreault, Ronna L. Chan, Amy H. Herring, Patricia V. Basta, David M. DeMarini

Mutat Res. Author manuscript; available in PMC 2012 Apr 8.

Published in final edited form as: Mutat Res. 2010 Jun 1; 688(1-2): 41–46. Published online 2010 Mar 7. doi: 10.1016/j.mrfmmm.2010.03.002

PMCID:: PMC3321349

Article PDF–318K

Select item 297469116.

Polymorphisms in GSTT1, GSTZ1, and CYP2E1, Disinfection By-products, and Risk of Bladder Cancer in Spain

Kenneth P. Cantor, Cristina M. Villanueva, Debra T. Silverman, Jonine D. Figueroa, Francisco X. Real, Monserrat Garcia-Closas, Nuria Malats, Stephen Chanock, Meredith Yeager, Adonina Tardon, Reina Garcia-Closas, Consol Serra, Alfredo Carrato, Gemma Castaño-Vinyals, Claudine Samanic, Nathaniel Rothman, Manolis Kogevinas

Environ Health Perspect. 2010 Nov; 118(11): 1545–1550. Published online 2010 Sep 12. doi: 10.1289/ehp.1002206

PMCID:: PMC2974691

Article PDF–754K

Select item 258179617.

Susceptibility genes for gentamicin-induced vestibular dysfunction

Stephen M. Roth, Scott M. Williams, Lan Jiang, Kalapurakkal S. Menon, John J. Jeka

J Vestib Res. Author manuscript; available in PMC 2008 Nov 10.

Published in final edited form as: J Vestib Res. 2008; 18(1): 59–68.

PMCID:: PMC2581796

Article PDF–397K

Select item 114261018.

Intronic CA-repeat and CA-rich elements: a new class of regulators of mammalian alternative splicing

Jingyi Hui, Lee-Hsueh Hung, Monika Heiner, Silke Schreiner, Norma Neumüller, Gregor Reither, Stefan A Haas, Albrecht Bindereif

EMBO J. 2005 Jun 1; 24(11): 1988–1998. Published online 2005 May 12. doi: 10.1038/sj.emboj.7600677

PMCID:: PMC1142610

Article PDF–497K

Select item 283736719.

Glutathione Pathway Genetic Polymorphisms and Lung Cancer Survival After Platinum-Based Chemotherapy

Ann M. Moyer, Zhifu Sun, Anthony J. Batzler, Liang Li, Daniel J. Schaid, Ping Yang, Richard M. Weinshilboum

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2011 Mar 3.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2010 Mar; 19(3): 811–821. Published online 2010 Mar 3. doi: 10.1158/1055-9965.EPI-09-0871

PMCID:: PMC2837367

Article PDF–1.5M

Select item 322884520.

A whole genome screen for HIV restriction factors

Li Liu, Nidia MM Oliveira, Kelly M Cheney, Corinna Pade, Hanna Dreja, Ann-Marie H Bergin, Viola Borgdorff, David H Beach, Cleo L Bishop, Matthias T Dittmar, Áine McKnight

Retrovirology. 2011; 8: 94. Published online 2011 Nov 14. doi: 10.1186/1742-4690-8-94