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Select item 111049411.

Group 1 metabotropic glutamate receptors trigger glutamate-induced intracellular Ca²⁺ signals and nitric oxide release in human brain microvascular endothelial cells

Sharon Negri, Pawan Faris, Giorgia Pellavio, Laura Botta, Matteo Orgiu, Greta Forcaia, Giulio Sancini, Umberto Laforenza, Francesco Moccia

Cell Mol Life Sci. 2020 Jun; 77(11): 2235–2253. Published online 2019 Aug 31. doi: 10.1007/s00018-019-03284-1

PMCID:: PMC11104941

Abstract Article PDF–2.7M

Select item 98654162.

Genetic Variant in GRM1 Underlies Congenital Cerebellar Ataxia with No Obvious Intellectual Disability

Maria S. Protasova, Tatiana V. Andreeva, Sergey A. Klyushnikov, Sergey N. Illarioshkin, Evgeny I. Rogaev

Int J Mol Sci. 2023 Jan; 24(2): 1551. Published online 2023 Jan 12. doi: 10.3390/ijms24021551

PMCID:: PMC9865416

Abstract Article PDF–1.5M

Select item 94984003.

A Novel Nonsense Variant in GRM1 Causes Autosomal Recessive Spinocerebellar Ataxia 13 in a Consanguineous Pakistani Family

Hammad Yousaf, Ambrin Fatima, Zafar Ali, Shahid M. Baig, Mathias Toft, Zafar Iqbal

Genes (Basel) 2022 Sep; 13(9): 1667. Published online 2022 Sep 17. doi: 10.3390/genes13091667

PMCID:: PMC9498400

Abstract Article PDF–452K

Select item 83105414.

Structural insights into the activation initiation of full-length mGlu1

Jinyi Zhang, Lu Qu, Lijie Wu, Xiaomeng Tang, Feng Luo, Weixiu Xu, Yueming Xu, Zhi-Jie Liu, Tian Hua

Protein Cell. 2021 Aug; 12(8): 662–667. Published online 2020 Dec 5. doi: 10.1007/s13238-020-00808-5

PMCID:: PMC8310541

Article PDF–967K

Select item 77491225.

Metabotropic glutamate receptor 1 is associated with unfavorable prognosis in ER-negative and triple-negative breast cancer

Anna E. M. Bastiaansen, A. Mieke Timmermans, Marcel Smid, Carolien H. M. van Deurzen, Esther S. P. Hulsenboom, Wendy J. C. Prager-van der Smissen, Renée Foekens, Anita M. A. C. Trapman-Jansen, Peter A. E. Sillevis Smitt, Theo M. Luider, John W. M. Martens, Martijn M. vanDuijn

Sci Rep. 2020; 10: 22292. Published online 2020 Dec 18. doi: 10.1038/s41598-020-79248-4

PMCID:: PMC7749122

Abstract Article PDF–1.7M

Select item 67322186.

Developmental regulation of group I metabotropic glutamate receptors in the premature brain and their protective role in a rodent model of periventricular leukomalacia

LAUREN L. JANTZIE, DELIA M. TALOS, DEBRA B. SELIP, LI AN, MICHELE C. JACKSON, REBECCA D. FOLKERTH, WENBIN DENG, FRANCES E. JENSEN

Neuron Glia Biol. Author manuscript; available in PMC 2019 Sep 8.

Published in final edited form as: Neuron Glia Biol. 2010 Nov; 6(4): 277–288. Published online 2011 Dec 14. doi: 10.1017/S1740925X11000111

PMCID:: PMC6732218

Abstract Article PDF–2.0M

Select item 62077347.

Metabotropic glutamate receptor-1 regulates inflammation in triple negative breast cancer

Rachel E. Sexton, Ali H. Hachem, Ali A. Assi, Miriam A. Bukhsh, David H. Gorski, Cecilia L. Speyer

Sci Rep. 2018; 8: 16008. Published online 2018 Oct 30. doi: 10.1038/s41598-018-34502-8

PMCID:: PMC6207734

Abstract Article PDF–1.9M

Select item 51930078.

Metabotropic glutamate receptor 1 disrupts mammary acinar architecture and initiates malignant transformation of mammary epithelial cells

Jessica L. F. Teh, Raj Shah, Stephanie La Cava, Sonia C. Dolfi, Madhura S. Mehta, Sameera Kongara, Sandy Price, Shridar Ganesan, Kenneth R. Reuhl, Kim M. Hirshfield, Vassiliki Karantza, Suzie Chen

Breast Cancer Res Treat. Author manuscript; available in PMC 2016 Dec 28.

Published in final edited form as: Breast Cancer Res Treat. 2015 May; 151(1): 57–73. Published online 2015 Apr 10. doi: 10.1007/s10549-015-3365-8

PMCID:: PMC5193007

Abstract Article PDF–1.1M

Select item 49836199.

Are Type 1 metabotropic glutamate receptors a viable therapeutic target for the treatment of cerebellar ataxia?

Emmet M. Power, Natalya A. English, Ruth M. Empson

J Physiol. 2016 Aug 15; 594(16): 4643–4652. Published online 2016 Feb 24. doi: 10.1113/JP271153

PMCID:: PMC4983619

Abstract Article PDF–631K

Select item 420133210.

Chemical Modulation of Mutant mGlu₁ Receptors Derived from Deleterious GRM1 Mutations Found in Schizophrenics

Hyekyung P. Cho, Pedro M. Garcia-Barrantes, John T. Brogan, Corey R. Hopkins, Colleen M. Niswender, Alice L. Rodriguez, Daryl F. Venable, Ryan D. Morrison, Michael Bubser, J. Scott Daniels, Carrie K. Jones, P. Jeffrey Conn, Craig W. Lindsley

ACS Chem Biol. 2014 Oct 17; 9(10): 2334–2346. Published online 2014 Aug 19. doi: 10.1021/cb500560h

PMCID:: PMC4201332

Abstract Article PDF–4.2M

Select item 411154611.

Identification of Novel GRM1 Mutations and Single Nucleotide Polymorphisms in Prostate Cancer Cell Lines and Tissues

Shafat Ali, Mojgan Shourideh, Shahriar Koochekpour

PLoS One. 2014; 9(7): e103204. Published online 2014 Jul 25. doi: 10.1371/journal.pone.0103204

PMCID:: PMC4111546

Abstract Article PDF–1.0M

Select item 400863812.

Activation of the Glutamate Receptor GRM1 Enhances Angiogenic Signaling to Drive Melanoma Progression

Yu Wen, Jiadong Li, Jasmine Koo, Seung-Shick Shin, Yong Lin, Byeong-Seon Jeong, Janice Mehnert, Suzie Chen, Karine Cohen-Solal, James S Goydos

Cancer Res. Author manuscript; available in PMC 2015 May 1.

Published in final edited form as: Cancer Res. 2014 May 1; 74(9): 2499–2509. Published online 2014 Feb 3. doi: 10.1158/0008-5472.CAN-13-1531

PMCID:: PMC4008638

Abstract Article PDF–1.9M

Select item 391016913.

Metabotropic Glutamate Receptor 1 (Grm1) Is An Oncogene In Epithelial Cells

Jeffrey J Martino, Brian A Wall, Elisa Mastrantoni, Barbara J Wilimczyk, Stephanie N La Cava, Kurt Degenhardt, E White, Suzie Chen

Oncogene. Author manuscript; available in PMC 2014 Mar 13.

Published in final edited form as: Oncogene. 2013 Sep 12; 32(37): 4366–4376. Published online 2012 Oct 22. doi: 10.1038/onc.2012.471

PMCID:: PMC3910169

Abstract Article PDF–3.1M

Select item 389817814.

Metabotropic Glutamate Receptor-1: A potential therapeutic target for the treatment of breast cancer

Cecilia L. Speyer, Jennifer S. Smith, Malathi Banda, John A. DeVries, Tassia Mekani, David H. Gorski

Breast Cancer Res Treat. Author manuscript; available in PMC 2014 Jan 22.

Published in final edited form as: Breast Cancer Res Treat. 2012 Apr; 132(2): 565–573. Published online 2011 Jun 17. doi: 10.1007/s10549-011-1624-x

PMCID:: PMC3898178

Article PDF–912K

Select item 389434415.

Extracellular Calcium Modulates Actions of Orthosteric and Allosteric Ligands on Metabotropic Glutamate Receptor 1α

Jason Y. Jiang, Mulpuri Nagaraju, Rebecca C. Meyer, Li Zhang, Donald Hamelberg, Randy A. Hall, Edward M. Brown, P. Jeffrey Conn, Jenny J. Yang

J Biol Chem. 2014 Jan 17; 289(3): 1649–1661. Published online 2013 Nov 26. doi: 10.1074/jbc.M113.507665

PMCID:: PMC3894344

Abstract Article PDF–2.5M

Select item 388025616.

Metabotropic Glutamate Receptor-1 Contributes to Progression in Triple Negative Breast Cancer

Malathi Banda, Cecilia L. Speyer, Sara N. Semma, Kingsley O. Osuala, Nicole Kounalakis, Keila E. Torres Torres, Nicola J. Barnard, Hyunjin J. Kim, Bonnie F. Sloane, Fred R. Miller, James S. Goydos, David H. Gorski

PLoS One. 2014; 9(1): e81126. Published online 2014 Jan 3. doi: 10.1371/journal.pone.0081126

PMCID:: PMC3880256

Abstract Article PDF–1.4M

Select item 372911417.

Two newly identified exons in human GRM1 express a novel splice variant of metabotropic glutamate 1 receptor

John O. DiRaddo, Sergey Pshenichkin, Tara Gelb, Jarda T. Wroblewski

Gene. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Gene. 2013 May 1; 519(2): 367–373. Published online 2013 Feb 24. doi: 10.1016/j.gene.2013.02.009

PMCID:: PMC3729114

Abstract Article PDF–694K

Select item 372488318.

Metabotropic Glutamate Receptor 1 Expression and Its Polymorphic Variants Associate with Breast Cancer Phenotypes

Madhura S. Mehta, Sonia C. Dolfi, Roman Bronfenbrener, Erhan Bilal, Chunxia Chen, Dirk Moore, Yong Lin, Hussein Rahim, Seena Aisner, Romona D. Kersellius, Jessica Teh, Suzie Chen, Deborah L. Toppmeyer, Dan J. Medina, Shridar Ganesan, Alexei Vazquez, Kim M. Hirshfield

PLoS One. 2013; 8(7): e69851. Published online 2013 Jul 26. doi: 10.1371/journal.pone.0069851

PMCID:: PMC3724883

Abstract Article PDF–1.0M

Select item 363120519.

Human Synaptic Plasticity Gene Expression Profile and Dendritic Spine Density Changes in HIV-Infected Human CNS Cells: Role in HIV-Associated Neurocognitive Disorders (HAND)

Venkata Subba Rao Atluri, Sudheesh P. Kanthikeel, Pichili V. B. Reddy, Adriana Yndart, Madhavan P. N. Nair

PLoS One. 2013; 8(4): e61399. Published online 2013 Apr 19. doi: 10.1371/journal.pone.0061399

PMCID:: PMC3631205

Abstract Article PDF–3.2M

Select item 351198220.

Autosomal-Recessive Congenital Cerebellar Ataxia Is Caused by Mutations in Metabotropic Glutamate Receptor 1

Velina Guergueltcheva, Dimitar N. Azmanov, Dora Angelicheva, Katherine R. Smith, Teodora Chamova, Laura Florez, Michael Bynevelt, Thai Nguyen, Sylvia Cherninkova, Veneta Bojinova, Ara Kaprelyan, Lyudmila Angelova, Bharti Morar, David Chandler, Radka Kaneva, Melanie Bahlo, Ivailo Tournev, Luba Kalaydjieva

Am J Hum Genet. 2012 Sep 7; 91(3): 553–564. doi: 10.1016/j.ajhg.2012.07.019

PMCID:: PMC3511982

Abstract Article PDF–1.3M

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Synthetic construct Homo sapiens clone IMAGE:100061789, MGC:190101 phosphoglycol...
Synthetic construct Homo sapiens clone IMAGE:100061789, MGC:190101 phosphoglycolate phosphatase (PGP) mRNA, encodes complete protein
gi|162318525|gb|BC156305.1|

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